A new organic π-conjugated quinolinium derivative was designed and synthesized in order to investigate the influence of the anion structure on characteristics of the crystal. The quinolinium derivative consists of a 2-(4-hydroxy-3-methoxystyryl)-1-methylquinolinium (HMQ) cation and a 4-vinylben...

A novel molecular design strategy for the synthesis of three A-D-A type 2, 3, 3, 8-tetramethyl-3H-pyrrolo [2, 3-f] quinoline-based semisquaraines, denoted as HSQ 1, HSQ 2 and HSQ 3 were developed to investigate the effect of additional pyridine acceptor on photophysical properties of these dyes....

4- and 5-((1-Methylquinolinium-3-yl)ethynyl)thiophene-2-carboxylates were prepared starting from 3-ethynylquinoline which was subjected to a Sonogashira-Hagihara coupling with ethyl 4- and 5-bromothiophenecarboxylates, respectively. Methylation to give the corresponding quinolinium salts, saponi...

Substitution around 5-methyl benzothieno[3,2-b]quinolinium (2) ring system was explored in order to identify positions of substitution that could improve its antifungal profile. The 3-methoxy (10b) was active against C. albicans, C. neoformans, and A. fumigatus and the 4-chloro (10f) analog show...

An organic quinolinium derivative nonlinear optical (NLO) crystal, 1-ethyl-2-[2-(4-nitro-phenyl)-vinyl]-quinolinium iodide (PNQI) was synthesized and successfully grown by slow evaporation solution growth technique. Formation of a crystalline compound was confirmed by single crystal X-ray diffra...

To develop new anti-inflammatory and DNA cleavage agent with improved pharmaceutical profile, five quilinium salt based compounds have been synthesized and x-ray characterization of these quinolinium salts have been reported here. These quinolinium salts have potential to show the better anti-in...

3-Ethynyl-1-methylpyridinium- and 3-ethynyl-1-methyl-quinolinium triflates were prepared by methylation of 3-ethynylpyridine and 3-ethynylquinoline with methyl triflate, respectively. Whereas deprotonation of the former mentioned salt gave no stable product, sodium hydroxide in methanol formed 1...

Filamenting temperature-sensitive mutant Z (FtsZ) is recognized as a promising target for new antibiotics development because of its high conservatism and pivotal role in the bacteria cell division. The aromatic heterocyclic scaffold of indole is known showing merit medical functions in antivira...

A series of π-conjugated vinyl N-methylated quinolinium salts (3) and their precursor's N-alkylated quinolinium salts (2) were prepared and characterized by NMR, IR, UV–Vis and MS spectroscopy. It was confirmed that the hydroxyl and amino derivatives of vinyl N-methylated quinolinium salt...

The title compound 9,9′-(4,4′-(silinane-1,1-diyl)bis(4,1-phenylene))bis(9H-carbazole) (6-bisCz) has been designed and prepared to investigate its crystal structure and photophysical and electrochemical properties. 6-bisCz is crystallized in the centrosymmetric space group P−1. Interestingly, t...

This paper reports on a new microporous composite silica membrane prepared via acid-catalyzed polymeric route of sol-gel method with tetraethylorthosilicate (TEOS) and a bridged silsesquioxane [1, 2-bis(triethoxysilyl)ethane, BTESE] as precursors. A stable nano-sized composite silica sol with a ...

Periodic mesoporous organosilica (PMO) have been prepared from bis(triethoxysilyl)methane (BTM) and cetyltrimethylammonium chloride (C16TAC). A large range of synthesis conditions (pH, C16TAC/BTM ratio, post-treatment and concentration) were used to study their effects on the structure of the as...

Bis(triethoxysilyl) methane (BTESM), which consists of Si–C–Si bonds, was used as a membrane precursor in the control of amorphous silica network size for separation of C3H6 and C3H8 molecules. Single and binary-component gas permeation/separation characteristics were examined at temperatures ...

Syntheses of new poly(trifunctional-silyl)alkanes, which are potent coupling agents of hybrid organic–inorganic materials have been thoroughly examined. Optimization of the Benkeser reaction using chloroform, trichlorosilane and tri-n-butylamine (respective ratios 1:4.5:3) afforded bis(trichlor...

Sol-gel urea functionalized-[bis(hydroxyethyl)amine] terminated polydimethylsiloxane coating was developed for capillary microextraction-high performance liquid chromatographic analysis from aqueous samples. A fused silica capillary is coated from the inside with surface bonded coating material ...

A highly enantioselective preparation (92–99% enantiomeric excess, 100% conversion) of various 4-aryl-2-hydroxy but-3-enoic carboxylic acid esters from the corresponding 4-phenyl-2-keto but-3-enoic acid esters mediated by plant cell cultures of Daucus carota under mild and environmentally benig...

Enantioselective, homogeneous hydrogenation of 3-phenyl-3-butenoic acid (1) has extensively been examined in the presence of the rhodium(I)/4,5-bis[(diphenylphosphino)methyl]-2,2-dimethyldioxolane (DIOP) catalyst systems. Optimization of the reaction conditions was undertaken mainly by controlli...

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) induced DNA strand-breakage (measured by fluorometric analysis of DNA unwinding) in human white blood cells at sub-cytotoxic doses (1.0–1000 μM; 60 min exposure). Although a dose-dependent decrease in glutathione levels was observed wit...

The oxidative decarboxylation of α-trifluoromethyl-α-hydroxy acids to trifluoromethyl ketones is carried out under mild catalytic aerobic conditions using a cobalt(III) complex in the presence of pivalaldehyde.

A controversy exists with respect to the mechanism of l-2-hydroxy acid oxidation by members of a family of FMN-dependent enzymes. A so-called carbanion mechanism was initially proposed, in which the active site histidine abstracts the substrate α-hydrogen as a proton, followed by electron trans...