AimsIncreasing nicotinamide adenine dinucleotide (NAD+) by Nicotinamide riboside (NR) provides protective benefits in multiple disorders. However, the role of NR on liver fibrosis is unclear. We performed in vivo and in vitro experiments to test the hepatic protective effects of NR against liver...

AimsNicotinamide Riboside (NR) is a NAD+ booster with wide physiological repercussion including the improvement on glucose and lipid homeostasis, increasing the life expectancy in mammals. However, the effects of NR on metabolism are only partially known. Here, we evaluated the effects of NR on ...

Nicotinamide riboside, the most recently discovered form of vitamin B3, and its phosphorylated form nicotinamide mononucleotide, have been shown to be potent supplements boosting intracellular nicotinamide adenine dinucleotide (NAD) levels, thus preventing or ameliorating metabolic and mitochond...

ObjectiveAugmenting nicotinamide adenine dinucleotide (NAD+) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD+. Here ...

AimsSepsis-caused multiple organ failure remains the major cause of morbidity and mortality in intensive care units. Nicotinamide riboside (NR) is a precursor of nicotinamide adenine dinucleotide (NAD+), which is important in regulating oxidative stress. This study investigated whether administr...

ObjectiveLiver fibrosis is part of the non-alcoholic fatty liver disease (NAFLD) spectrum, which currently has no approved pharmacological treatment. In this study, we investigated whether supplementation of nicotinamide riboside (NR), a nicotinamide adenine dinucleotide (NAD+) precursor, can re...

Extraction of Prussian Blue into chloroform in the presence of ajatin (dimethyl-lauryl-benzylammonium bromide) is proposed for the concentration and determination of ferrocyanide ion. Optimum concentrations of sulphuric acid and of ajatin have been established and the selectivity of the extracti...

A gas-liquid chromatographic study of the adsorption properties of a stationary phase containing a mixture of squalane and Bentone 34Activity coefficients of n-alkanes and aromatic hydrocarbons such as toluene and xylenes solutions in a mixture of squalane and Bentone 34 are determined by gas-li...

Gels of Bentone 38—Celite (I:I) in toluence canb e spread on glass plates in the usual way for thin-layer chromatography. After evaporation of the solvent, they form very thin lipophilic films which are suitable for the separation of isomeric polyphenyls.The following compounds were chromatogra...

RésuméLes possibilités de séparation d'une phase stationnaire constituée par le mélange de Bentone 34 et de graisse de silicones ont été déterminées.Ainse, non seulement les isomères des xylènes, des dichlorobenzènes ou des diéthylbenzènes peuvent être séparés, mais aussi ...

Gas chromatographic retention ratios are reported for 49 compounds in the thiophene, benzo(b)thiophene, pyridine, quinoline, isoquinoline, and thienopyridine ring systems, variously substituted with alkyl and halo groups. Stationary phases of Silicone DC 710 and of Bentone 34-Silicone DC 710 on ...

Gas chromatographic retention data are reported for sixteen alkenyl- and cycloalkenylnaphthalenes with stationary phases of Bentone 34; silicone fluid DC 550, and Apiezon L at 200°C. Retention data with the silicone and apiezon phases are interpreted in terms of volatility of the solute, which ...

The gelation process of industrial organo-bentone in organic solvents is a complex phenomenon due to various parameters, such as, the crystallographic nature of the clay, the nature of adsorbed surfactant, the dielectric constant of medium. Sol-gel phase diagrams have been established by varying...

SummaryThe motility of bovine sperm in undiluted semen ceased within 30 seconds after the addition of 0.5 per cent Amphyl, a disinfectant containing synthetic organic compounds.Indications are that sperm, suspended in an egg yolk-phosphate buffer dilution medium containing from 0.2 to 0.5 per ce...

The reaction of urea with K2PtCl4 and the formation of a non-stoichiometric olive green complex is reported. The complex has been studied by infrared, Raman, UV and 195Pt NMR spectroscopy and by chemical methods.

1.1. Seven hundred and ninety-three kala-azar patients in North-west China were treated with urea stibamine during July, 1944, and June, 1946, and the period of observation extended to June, 1947:Of this total, 449 patients received the treatment once a week, and 344 twice a week.2.2. While the ...

The antileishmanial antimonial drug urea stibamine was encapsulated in mannosylated and nonmannosylated liposomes and was tested against experimental leishmanial infection in hamsters. The study demonstrated that liposome encapsulation of urea stibamine enhanced its effectiveness, an effect whic...

An improved method for preparation of urea stibamine was developed. The crude p-acetylaminophenyl stibonic acid (II) prepared was purified by dissolving it in Na2CO3 solution, whererin acid (II) dissolved leaving behind the impurities. Acid (II) was directly combined with urea without hydrolyzin...

3-Carboxy-4-methyl-5-propyl-2-furanpropionic acid, 3-carboxy-4-methyl-5-pentyl-2-furanpropionic acid, 3-carboxy-4-methyl-5-ethyl-2-furanpropionic acid and 3-carboxy-5-propyl-2-furanpropionic acid were detected in uremic serum using gas chromatography-mass spectrometry. Mass chromatography reveal...

Derivatives of 2- and 3-benzo[b]furancarboxylic acids were prepared and evaluated for their cytotoxic potential in the National Cancer Institute, Bethesda, USA. Six compounds: 7-acetyl-6-hydroxy-3-methyl-2-benzofurancarboxylic acid (2), 6-hydroxy-7-(p-methoxycinnamoyl)-3-methyl-2-benzofurancarbo...