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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Boc-3-piperidone Manufacturer/High quality/Best price/In stock

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1-(tert-Butoxycarbonyl)-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. Product quality, process, price and service 1-Boc-3-piperidone CAS 98977-36-7 IN Stock tert-Butyl 3-oxopiperidine-1-carboxylate CAS 98977-36-7 98977-36-7 CAS 98977-36-7 hig

1-Boc-3-piperidone CAS 98977-36-7 IN Stock tert-Butyl 3-oxopiperidine-1-carboxylate CAS 98977-36-7

Cas:98977-36-7

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

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Ality Chemical Corporation

1-Boc-3-piperidone Basic information Product Name: 1-Boc-3-piperidone Synonyms: T-BUTYL-3-PIPERIDONE-1-CARBOXYLATE;TERT-BUTYL 3-OXOPIPERIDINE-1-CARBOXYLATE;N-Boc-3-piperidone;N-BOC-3-PIPERIDINONE;3-OXOPIPERIDINE, N-BOC PROTECTED;3-OXO-PIPERIDIN

Factory Supply 1-Boc-3-Piperidone

Cas:98977-36-7

Min.Order:1 Gram

Negotiable

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

1-Boc-3-piperidone -

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Gram

FOB Price: $12.0 / 15.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer CAS 98977-36-7 with fast shipping

Cas:98977-36-7

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 1-Boc-3-piperidone Synonyms: tert-butyl-3-oxopiperidine-1-carboxylate CAS: 98977-36-7 MF: C10H17NO3 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:APIs Transportation:By sea or

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:colorless liquid Storage: 2-8°C Package:200kg/Drum Application:1-Boc-3-piperidone, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. Transportation:Express/Sea/

1-Boc-3-piperidone with high quality

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Boc-3-piperidone 98977-36-7

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1-Boc-3-piperidone CAS: 98977-36-7 MF: C10H17NO3 MW: 199.25 EINECS: 629-575-1 Mol File: 98977-36-7.mol 1-Boc-3-piperidone Structure 1-Boc-3-piperidone Chemical Properties Melting point 35-40 °C (lit.) Boiling

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $47.0 / 50.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

1-Boc-3-piperidone CAS:98977-36-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

1-Boc-3-piperidone CAS:98977-36-7

Cas:98977-36-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:98977-36-7

Cas:98977-36-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Triumph International Development Limilted

Appearance:White to yellow semisolid or solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Avarofloxacin intermediate Transportation:Common products:Sea/Air/Co

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhengzhou Yuanli Biological Technology Co., Ltd.

Product Name: 1-Boc-3-piperidone CAS No.:98977-36-7 Molecular Formula:C10H17NO3 Molecular Weight:199.25 Assay: 98% Place of Origin: CN EINECS NO : 629-575-1 We could give you: 1.Fast response to customer within 6 hours 2.Lower Price with hi

98% 1-Boc-3-piperidone factory supply;98977-36-7

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-tert-butoxycarbonyl-3-piperidone

Cas:98977-36-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

1-Boc-3-piperidone CAS 98977-36-7 Description Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict

1-Boc-3-piperidone CAS 98977-36-7

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Boc-3-piperidinone

Cas:98977-36-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Best price/In stock 1-Boc-3-piperidone 98977-36-7

Cas:98977-36-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage: 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good quali

1-Boc-3-Piperidinone

Cas:98977-36-7

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-(tert-Butoxycarbonyl)-3-piperidone

Cas:98977-36-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:White to yellow low melting solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Interm

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: N-Boc-3-Piperidone CAS No.:98977-36-7 Molecule Formula:C10H17NO3 Molecule Weight:199.25 Purity: 97.0% Package: 25kg/drum Description:White or yellow powder Manufacture Standards:Enterprise Standard TE

High Quality N-Boc-3-Piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Boc-3-piperidone

Cas:98977-36-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

N-tert-butoxycarbonyl-3-piperidinol
85275-45-2

N-tert-butoxycarbonyl-3-piperidinol

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sodium hypochlorite solution; sodium hydrogencarbonate; potassium bromide In dichloromethane at 5 - 10℃; pH=8.5; Reagent/catalyst;99.4%
With Dess-Martin periodane In dichloromethane at 20℃; for 22h; Inert atmosphere;97%
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide In diethyl ether; water; toluene at 0 - 4℃;95%
1-benzyl-piperidin-3-one hydrochloride hydrate

1-benzyl-piperidin-3-one hydrochloride hydrate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With hydrogen; palladium dihydroxide In methanol; dichloromethane97%
1-benzyl-3-piperidone
40114-49-6

1-benzyl-3-piperidone

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 1-benzyl-3-piperidone With hydrogenchloride; palladium 10% on activated carbon; hydrogen In methanol; water at 20℃; for 2h;
Stage #2: With N-ethyl-N,N-diisopropylamine In methanol; water for 0.5h;
Stage #3: di-tert-butyl dicarbonate In methanol; water at 20℃; for 5h; Concentration; Reagent/catalyst;
84.2%
C12H23NO4S
1179348-67-4

C12H23NO4S

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)diiridium(I) dichloride In 1,2-dichloro-ethane at 70℃;82%
With bis(1,5-cyclooctadiene)diiridium(I) dichloride In 1,2-dichloro-ethane at 70℃; for 18h; Inert atmosphere;82%
oxalyl dichloride
79-37-8

oxalyl dichloride

N-tert-butoxycarbonyl-3-piperidinol
85275-45-2

N-tert-butoxycarbonyl-3-piperidinol

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With ammonium chloride; trimethylamine In dichloromethane; dimethyl sulfoxide78%
tert-butyl 3-methylidenepiperidine-1-carboxylate
276872-89-0

tert-butyl 3-methylidenepiperidine-1-carboxylate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With 2,6-dimethylpyridine; sodium periodate; ruthenium(III) chloride trihydrate In dichloromethane; water; acetonitrile at 20℃; for 1h; Inert atmosphere;68%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0℃; for 2h; Yield given;
With sodium hydrogencarbonate In tetrahydrofuran for 4h;2.93 g
With sodium hydrogencarbonate In tetrahydrofuran; water for 4h;
C12H24NO3S(1+)*Cl(1-)

C12H24NO3S(1+)*Cl(1-)

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; for 1h; Swern oxidation;
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

1-benzyl-3-piperidone monohydrochloride monohydrate

1-benzyl-3-piperidone monohydrochloride monohydrate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 1-benzyl-3-piperidone monohydrochloride monohydrate With hydrogen; palladium on activated charcoal In methanol under 2844.31 Torr;
Stage #2: di-tert-butyl dicarbonate With sodium hydrogencarbonate In tetrahydrofuran for 48h;
56.6 g
3-hydroxypiperazine
6859-99-0

3-hydroxypiperazine

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / tetrahydrofuran; H2O / 1 h / 20 °C
2: triethylamine; SO3*NMe3; DMSO / 18 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaOH / H2O; tetrahydrofuran / 1 h / 20 °C
2: 15.6 g / triethylamine; trioxide-trimethylamine complex / dimethylsulfoxide / 18 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaOH / tetrahydrofuran; H2O / 1 h / 20 °C
2: 15.6 g / DMSO; SO3*Me3N; triethylamine / 18 h / 20 °C
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / tetrahydrofuran; H2O / 1 h / 20 °C
2: triethylamine; SO3*NMe3; DMSO / 18 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaOH / H2O; tetrahydrofuran / 1 h / 20 °C
2: 15.6 g / triethylamine; trioxide-trimethylamine complex / dimethylsulfoxide / 18 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 90 percent / NaHCO3 / tetrahydrofuran / 14 h
2: tetrapropylammonium perruthenate; NMO; 4A molecular sieves / CH2Cl2; acetonitrile / 1 h
View Scheme
N-benzyl-3-piperidinone hydrochloride
50606-58-1

N-benzyl-3-piperidinone hydrochloride

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / Pd/C / methanol; H2O / 16 h / 2844.31 Torr
2: 2.93 g / aq. NaHCO3 / tetrahydrofuran / 4 h
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

1.) NaH; 2.) SOCl2

1.) NaH; 2.) SOCl2

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / tetrahydrofuran; H2O / 1 h / 20 °C
2: 15.6 g / DMSO; SO3*Me3N; triethylamine / 18 h / 20 °C
View Scheme
3-hydroxypiperazine
6859-99-0

3-hydroxypiperazine

A

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

B

p-F-C6H4-Hal

p-F-C6H4-Hal

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CH2Cl2
2: SO3*pyridine; Et3N / CH2Cl2
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

A

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

B

p-F-C6H4-Hal

p-F-C6H4-Hal

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CH2Cl2
2: SO3*pyridine; Et3N / CH2Cl2
View Scheme
3-hydroxypiperazine
6859-99-0

3-hydroxypiperazine

paraformaldehyde

paraformaldehyde

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: Cr2O3, Ac2O, Py / CH2Cl2
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

pentacarbonyl<1-<<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl>oxy>-(E)-3-phenyl-2-propenylidene>chromium

pentacarbonyl<1-<<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl>oxy>-(E)-3-phenyl-2-propenylidene>chromium

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: Cr2O3, Ac2O, Py / CH2Cl2
View Scheme
1-Benzyl-3,3-dihydroxypiperidine hydrobromide
61995-16-2

1-Benzyl-3,3-dihydroxypiperidine hydrobromide

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / 10percent Pd/C / ethanol; H2O / 2205.2 Torr
2: triethylamine / tetrahydrofuran / 2 h / 0 °C
View Scheme
1-benzyl-3-piperidone
40114-49-6

1-benzyl-3-piperidone

tert-butyldicarbonate
34619-03-9

tert-butyldicarbonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With hydrogen; triethylamine; 20% palladium hydroxide on carbon In methanol at 50℃; under 3102.97 Torr; for 0.666667h;
3-hydroxypiperazine
6859-99-0

3-hydroxypiperazine

aqueous sodium hypochlorite

aqueous sodium hypochlorite

aqueous sodium bisulphite

aqueous sodium bisulphite

TEMPO
5132-07-0

TEMPO

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium bromide; sodium chloride; sodium hydrogencarbonate In dichloromethane; water
tetrapropylammonium perruthennate
114615-82-6

tetrapropylammonium perruthennate

4-methylmorpholine N-oxide
7529-22-8

4-methylmorpholine N-oxide

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
molecular sieves In dichloromethane
N-tert-butoxycarbonyl-3-piperidinol
85275-45-2

N-tert-butoxycarbonyl-3-piperidinol

Dess-Martin periodane
87413-09-0

Dess-Martin periodane

sodium thiosulfate

sodium thiosulfate

A

(1H-Benzoimidazol-2-ylmethyl)-(2-piperidin-3-ylidene-ethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine (hydrobromide salt)

(1H-Benzoimidazol-2-ylmethyl)-(2-piperidin-3-ylidene-ethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine (hydrobromide salt)

B

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With NaHCO3 In dichloromethaneA 1.80 g (95%)
B n/a
tert‐butyl 3‐aminopiperidine‐1‐carboxylate
144243-24-3

tert‐butyl 3‐aminopiperidine‐1‐carboxylate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With recombinant Rhodobacter sphaeroides amine-transaminase In dimethyl sulfoxide at 20℃; pH=7.5; aq. buffer; Enzymatic reaction;
tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
143900-43-0

tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene In dichloromethane at 20℃;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

piperidin-3-one hydrochloride

piperidin-3-one hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In dichloromethane; ethyl acetate at 20℃; for 1.5h;100%
With hydrogenchloride In water at 20℃;63%
With hydrogenchloride In 1,4-dioxane; dichloromethane at 20℃; for 3h;
With hydrogenchloride In diethyl ether; dichloromethane at 20℃; for 3h;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

toluene-4-sulfonic acid hydrazide
1576-35-8

toluene-4-sulfonic acid hydrazide

1,1-dimethylethyl 3-[2-[(4-methylphenyl)sulphonyl]hydrazono]-1-piperidinecarboxylate
396730-46-4

1,1-dimethylethyl 3-[2-[(4-methylphenyl)sulphonyl]hydrazono]-1-piperidinecarboxylate

Conditions
ConditionsYield
In dichloromethane for 2h;100%
methylmagnesium bromide
75-16-1

methylmagnesium bromide

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-hydroxy-3-methylpiperidine-1-carboxylate
1104083-27-3

tert-butyl 3-hydroxy-3-methylpiperidine-1-carboxylate

Conditions
ConditionsYield
With ammonium chloride In tetrahydrofuran; diethyl ether at 0 - 20℃; for 18h; Inert atmosphere;100%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

3-amino-piperidin-3-yl-phosphonic acid

3-amino-piperidin-3-yl-phosphonic acid

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With acetamide; acetic acid; acetyl chloride at 20℃; Cooling with ice;
Stage #2: With phosphorus trichloride at 75℃; Cooling with ice;
Stage #3: With hydrogenchloride In water for 8h; Reflux;
100%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl (3S)-3-aminopiperidine-1-carboxylate
625471-18-3

tert-butyl (3S)-3-aminopiperidine-1-carboxylate

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; isopropylamine In dimethyl sulfoxide at 50℃; for 50h; pH=7.5; Reagent/catalyst; Temperature; Enzymatic reaction; enantioselective reaction;99%
With pyridoxal 5'-phosphate; transaminase pQR2189; isopropylamine In aq. phosphate buffer; dimethyl sulfoxide at 35℃; for 18h; pH=7.5; Kinetics; Reagent/catalyst;60 %Chromat.
7-chloroisoquinolin-5-amine

7-chloroisoquinolin-5-amine

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-((7-chloroisoquinolin-5-yl)amino)piperidine-1-carboxylate

tert-butyl 3-((7-chloroisoquinolin-5-yl)amino)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 7-chloroisoquinolin-5-amine; 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With acetic acid at 20℃; for 0.5h;
Stage #2: With sodium tris(acetoxy)borohydride at 20℃; for 18h;
99%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
143900-44-1

tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate

Conditions
ConditionsYield
With rac-octan-2-ol In aq. buffer at 35℃; for 12h; pH=8; Reagent/catalyst; pH-value; Temperature; Enzymatic reaction; enantioselective reaction;98.08%
With D-glucose; NADP In aq. phosphate buffer; ethanol at 30℃; for 4h; pH=6; enantioselective reaction;96%
With recombinant Rhodococcus erythropolis DSM 43297 ketoredutase; nicotinamide adenine dinucleotide In aq. phosphate buffer; isopropyl alcohol at 50℃; for 0.5h; pH=7.0; Enzymatic reaction; stereoselective reaction;95%
N,N-phenylbistrifluoromethane-sulfonimide
37595-74-7

N,N-phenylbistrifluoromethane-sulfonimide

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

5-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
149108-74-7

5-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78 - 0℃; for 3.25h;
98%
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 2h;
Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78 - 20℃;
85%
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at 20℃; Inert atmosphere;
44%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

5-phenyl-1,2,3,6-tetrahydropyridine

5-phenyl-1,2,3,6-tetrahydropyridine

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester; phenylmagnesium bromide In tetrahydrofuran at 0℃; for 1.5h; Inert atmosphere;
Stage #2: With trifluoroacetic acid at 22 - 75℃;
98%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

tert-butyl 3-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester In tetrahydrofuran at 20℃; for 5h; Horner-Wadsworth-Emmons Olefination;
98%
t-butoxycarbonylhydrazine
870-46-2

t-butoxycarbonylhydrazine

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl (3E)-3-[(tert-butoxycarbonyl)hydrazono]piperidine-1-carboxylate
1305274-91-2

tert-butyl (3E)-3-[(tert-butoxycarbonyl)hydrazono]piperidine-1-carboxylate

Conditions
ConditionsYield
In toluene at 60℃; for 4h;95%
2-aminoacetophenone
551-93-9

2-aminoacetophenone

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

C18H22N2O2
1347747-90-3

C18H22N2O2

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate; N,N-dimethyl-formamide at 90℃; Friedlaender reaction;95%
(S)-cyclopentyl 2-amino-4-methylpentanoate 4-methylbenzenesulfonate
914382-66-4

(S)-cyclopentyl 2-amino-4-methylpentanoate 4-methylbenzenesulfonate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

cyclopentyl N-[1-(tert-butoxycarbonyl)piperidin-3-yl]-L-leucinate
1351815-36-5

cyclopentyl N-[1-(tert-butoxycarbonyl)piperidin-3-yl]-L-leucinate

Conditions
ConditionsYield
Stage #1: (S)-cyclopentyl 2-amino-4-methylpentanoate 4-methylbenzenesulfonate; 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With sodium tris(acetoxy)borohydride In 1,1-dichloroethane at 20℃; for 18h;
Stage #2: With sodium hydrogencarbonate In 1,1-dichloroethane; water at 20℃; for 0.333333h;
95%
5-amino-3,4-dimethylisoxazol
19947-75-2

5-amino-3,4-dimethylisoxazol

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-[(3,4-dimethyl-1,2-oxazol-5-yl)amino]piperidine-1-carboxylate

tert-butyl 3-[(3,4-dimethyl-1,2-oxazol-5-yl)amino]piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 5-amino-3,4-dimethylisoxazol; 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With acetic acid In 1,2-dichloro-ethane at 25℃; for 1h;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 0 - 25℃; for 48h;
95%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

acetylenemagnesium bromide
4301-14-8

acetylenemagnesium bromide

tert-butyl 3-ethynyl-3-hydroxypiperidine-1-carboxylate
287192-85-2

tert-butyl 3-ethynyl-3-hydroxypiperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester; acetylenemagnesium bromide In tetrahydrofuran at 0℃; for 4h;
Stage #2: With ammonium chloride In tetrahydrofuran; water
94%
In tetrahydrofuran at 0 - 20℃; for 12h;80%
N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

4-((dimethylamino)methylene)-3-oxopiperidine-1-carboxylic acid tert-butyl ester
871726-72-6

4-((dimethylamino)methylene)-3-oxopiperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
at 100℃; for 2h;94%
In N,N-dimethyl-formamide at 80℃; for 12h;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

C10H18N2O2

C10H18N2O2

Conditions
ConditionsYield
With ammonium acetate In ethanol for 7h; Reflux; Large scale;93.7%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
143900-43-0

tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate

Conditions
ConditionsYield
With recombinant Chryseobacterium sp. CA 49 ketoreductase; nicotinamide adenine dinucleotide In aq. phosphate buffer; isopropyl alcohol at 40℃; for 6h; pH=7.0; Enzymatic reaction; stereoselective reaction;93%
With SmADH31 Kinetics; Enzymatic reaction; stereoselective reaction;89%
5-bromo-3-methyl-6-oxo-1,6-dihydropyridine-2-carboxamide

5-bromo-3-methyl-6-oxo-1,6-dihydropyridine-2-carboxamide

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

6-bromo-8-methyl-2H-spiro[imidazo[1,5-a]pyridine-3,3'-piperidine]-1,5-dione hydrochloride

6-bromo-8-methyl-2H-spiro[imidazo[1,5-a]pyridine-3,3'-piperidine]-1,5-dione hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane at 110℃; for 16h; Sealed tube;93%
1-(5-Amino-1H-indazol-1-yl)-2,2-dimethylpropan-1-one Maleate
1035096-74-2

1-(5-Amino-1H-indazol-1-yl)-2,2-dimethylpropan-1-one Maleate

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(1-pivaloyl-1H-indazol-5-ylamino)piperidine-1-carboxylate
1035096-75-3

tert-butyl 3-(1-pivaloyl-1H-indazol-5-ylamino)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 1-(5-Amino-1H-indazol-1-yl)-2,2-dimethylpropan-1-one Maleate; 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 1h;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane
91%
Stage #1: 1-(5-Amino-1H-indazol-1-yl)-2,2-dimethylpropan-1-one Maleate; 3-oxo-piperidine-1-carboxylic acid tert-butyl ester In 1,2-dichloro-ethane at 20℃; for 1h; Inert atmosphere;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane
Stage #3: With sodium hydrogencarbonate In 1,2-dichloro-ethane
(4-fluorobenzyl)magnesium chloride
1643-73-8

(4-fluorobenzyl)magnesium chloride

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(4-fluorobenzyi)-3-hydroxypiperidine-1-carboxylate

tert-butyl 3-(4-fluorobenzyi)-3-hydroxypiperidine-1-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 3h;90%
In tetrahydrofuran at 20℃; for 3h;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

2-nitrobenzyl chloride
610-14-0

2-nitrobenzyl chloride

tert-butyl 4-(2-nitrobenzoyl)-3-carbonylpiperidine-1-carboxylate

tert-butyl 4-(2-nitrobenzoyl)-3-carbonylpiperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78 - -40℃; for 1h; Inert atmosphere;
Stage #2: 2-nitrobenzyl chloride In tetrahydrofuran at -40 - 30℃; for 3h; Inert atmosphere;
90%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-yl)-2H-pyran-3-carbonitrile
518308-79-7

6-(4-chlorophenyl)-2-oxo-4-(piperidin-1-yl)-2H-pyran-3-carbonitrile

tertbutyl 8-(4-chlorophenyl)−5-cyano-6-(piperidin-1-yl)−3,4-dihydroquinoline-1(2H)-carboxylate

tertbutyl 8-(4-chlorophenyl)−5-cyano-6-(piperidin-1-yl)−3,4-dihydroquinoline-1(2H)-carboxylate

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.8h; Irradiation; Sonication; Green chemistry;89%
With sodium amide; dimethyl sulfoxide at 25 - 35℃; for 3h; regioselective reaction;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

6-(4-chloro-phenyl)-2-oxo-4-(4-phenyl-piperazin-1-yl)-2H-pyran-3-carbonitrile
388573-73-7

6-(4-chloro-phenyl)-2-oxo-4-(4-phenyl-piperazin-1-yl)-2H-pyran-3-carbonitrile

tertbutyl 8-(4-chlorophenyl)−5-cyano-6-(4-phenylpiperazin-1-yl)−3,4-dihydroquinoline-1(2H)-carboxylate

tertbutyl 8-(4-chlorophenyl)−5-cyano-6-(4-phenylpiperazin-1-yl)−3,4-dihydroquinoline-1(2H)-carboxylate

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.833333h; Irradiation; Sonication; Green chemistry;89%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(dimethylamino)piperidinyl-1-carboxylate
1000576-83-9

tert-butyl 3-(dimethylamino)piperidinyl-1-carboxylate

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃;
Stage #2: With sodium hydrogencarbonate In water; 1,2-dichloro-ethane
88%
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

dimethyl amine
124-40-3

dimethyl amine

tert-butyl 3-(dimethylamino)piperidinyl-1-carboxylate
1000576-83-9

tert-butyl 3-(dimethylamino)piperidinyl-1-carboxylate

Conditions
ConditionsYield
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester; dimethyl amine In tetrahydrofuran; dichloromethane at 20℃; for 0.0833333h;
Stage #2: With sodium tris(acetoxy)borohydride In tetrahydrofuran; dichloromethane at 20℃;
88%
Stage #1: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester; dimethyl amine In ethanol at 0 - 20℃; for 2h;
Stage #2: With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; for 16h;
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

C10H19NO3

C10H19NO3

Conditions
ConditionsYield
With NAD; isopropyl alcohol In aq. phosphate buffer at 30℃; for 12h; pH=7; Reagent/catalyst; Microbiological reaction; Green chemistry; Enzymatic reaction; stereoselective reaction;88%
6-azaindole
271-29-4

6-azaindole

3-oxo-piperidine-1-carboxylic acid tert-butyl ester
98977-36-7

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

tert-butyl 5-(1H-pyrrolo[2,3-c]pyridin-3-yl)-3,4-dihydropyridine-1(2H)-carboxylate

tert-butyl 5-(1H-pyrrolo[2,3-c]pyridin-3-yl)-3,4-dihydropyridine-1(2H)-carboxylate

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 75℃; for 48h;87%
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