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Jinan Finer Chemical Co., Ltd

Product Description Product Name 4'-Methyl-2-cyanobiphenyl CAS No. 114772-53-1 Appearance White crystalline powder Assay ≥99% Capacity 300mt/year Min.packi

4'-Methyl-2-cyanobiphenyl

Cas:114772-53-1

Min.Order:1 Gram

FOB Price: $22.0

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4'-Methyl-2-cyanobiphenyl Manufacturer/High quality/Best price/In stock

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4'-Methyl-2-cyanobiphenyl supplier in China

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 99.9%min 99.9% Hangzhou Dingyan Chem is a leading manufacturer and supplier of che

High quality 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High quality 2-Cyano-4'-methylbiphenyl

Cas:114772-53-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Off-white crystalline powder Storage:2-8°C Package:25kg/drum

Sartan intermediate 2-Cyano-4-Methylbiphenyl (OTBN) CAS 114772-53-1 with best price

Cas:114772-53-1

Min.Order:25 Kilogram

FOB Price: $15.0 / 25.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of custom Application:intermediate Transportation:According to the demand of custom Port:shanghai

114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-cyano-4'-methylbiphenyl

Cas:114772-53-1

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Cyano-4'-Methylbiphenyl

Cas:114772-53-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

4'-Methyl-2-cyanobiphenyl CAS 114772-53-1 In stock

Cas:114772-53-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details Item Specification Test Results Appearance White crystalline powder Conform

China Biggest factory Supply High Quality 4'-Methyl-2-cyanobiphenyl 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM-- 114772-53-1--High purity 4'-Methyl-2-cyanobiphenyl in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established s

TIANFUCHEM-- 114772-53-1--High purity 4'-Methyl-2-cyanobiphenyl in stock

Cas:114772-53-1

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

4′ -Methyl-2-Cyanobiphenyl CAS 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Discount price CAS 114772-53-1 with best quality

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4'-Methyl-2-cyanobiphenyl/ LIDE PHARMA- Factory supply / Best price

Cas:114772-53-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name: 2-Cyano-4'-methylbiphenyl (4'-Methyl-2-biphenylcarbonitrile) Reference: OTBN CAS RN: 114772-53-1 Assay: ≥99.0%(HPLC) MF: C1

4'-Methyl-2-cyanobiphenyl CAS: 114772-53-1

Cas:114772-53-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

CAS 114772-53-1 Pharma Pharmaceutical Intermediate 4'-Methyl-2-cyanobiphenyl

Cas:114772-53-1

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4'-Methyl-2-cyanobiphenyl 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

2-Cyano-4'-methylbiphenyl

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Product Name: 4'-Methyl-2-cyanobiphenyl CAS: 114772-53-1 MF: C14H11N MW: 193.24 EINECS: 422-310-9 Mol File: 114772-53-1.mol 4'-Methyl-2-cyanobiphenyl Structure 4'-Methyl-2-cyanobiphenyl Chemical Properties Melting poin

4'-Methyl-2-cyanobiphenyl

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4'-Methyl-2-cyanobiphenyl CAS:114772-53-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

4'-Methyl-2-cyanobiphenyl CAS:114772-53-1

Cas:114772-53-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Cyano-4'-methylbiphenyl

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

High quality 2-Cyano-4'-methylbiphenyl CAS NO.114772-53-1

Cas:114772-53-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 114772-53-1 4'-Methyl-2-cyanobiphenyl

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo

Factory Price 4 -Methyl-2-Cyanobiphenyl CAS 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4'-Methyl-2-cyanobiphenyl

Cas:114772-53-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting4'-Methyl-2-cyanobiphenyl 99% (OTBN) CAS:114772-53-1, Please contact us by email freely. We are leading exporter in China. If y

4'-Methyl-2-cyanobiphenyl 99% (OTBN) CAS:114772-53-1 from FandaChem

Cas:114772-53-1

Min.Order:1 Metric Ton

Negotiable

Type:Other

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Cyano-4’-Methyl Biphenyl

Cas:114772-53-1

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA

93717-55-6 cas 99% OTBN 4'-Methyl-2-cyanobiphenyl cas 114772-53-1

Cas:114772-53-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Synthetic route

2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With potassium carbonate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate In n-heptane; water at 60℃; for 1.66667h; Suzuki Coupling; Inert atmosphere;100%
With potassium carbonate In water; isopropyl alcohol at 100℃; for 7h; Catalytic behavior; Suzuki-Miyaura Coupling; Inert atmosphere;100%
With bis({5-chloro-2-[(4-chlorophenyl)(hydroxyimino)methyl]phenyl})cyclodipalladachl-orane-1,3,4-tris(ylium)-2-uide; tetra(n-butyl)ammonium hydroxide; potassium carbonate; tri tert-butylphosphoniumtetrafluoroborate In N,N-dimethyl-formamide at 130℃; for 0.666667h; Suzuki-Miyaura coupling; Microwave irradiation;99%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate In 1,4-dioxane; water at 50℃; for 5h; Suzuki-Miyaura Coupling; Inert atmosphere;100%
With potassium carbonate; [1-cyclohexyl-3-(di-pyridin-2-yl-methyl)-urea][PdCl2] In water at 100℃; for 1h; Suzuki-Miyaura coupling;99%
With potassium carbonate; palladium dichloride In water; N,N-dimethyl-formamide at 20℃; for 0.0833333h; Suzuki cross-coupling reaction;99%
4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; TPGS-750-M; triethylamine In water at 40℃; Inert atmosphere;99%
With potassium carbonate In ethanol; water at 120℃; for 2.5h; Suzuki-Miyaura reaction; continuous flow reactor;54%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

para-methylphenylmagnesium bromide
4294-57-9

para-methylphenylmagnesium bromide

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With C35H31BrN4NiP In tetrahydrofuran at 25℃; for 17h; Schlenk technique; Inert atmosphere;98%
Stage #1: para-methylphenylmagnesium bromide With zinc(II) chloride In tetrahydrofuran at 20℃; for 0.333333h;
Stage #2: 2-Chlorobenzonitrile With bis(tri-t-butylphosphine)palladium(0) In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 100℃; for 24h; Negishi reaction; Further stages.;
97%
With chloro(1,3-bis(pyridin-2-ylmethyl)imidazolylidene)nickel(II) hexafluorophosphate In tetrahydrofuran at 20℃; for 12h; Kumada-Corriu coupling reaction; Inert atmosphere;85%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4'-methyl-2-acetyl-1,1'-biphenyl
16927-79-0

4'-methyl-2-acetyl-1,1'-biphenyl

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With cesium fluoride; Pd(dba)2 In 1,4-dioxane98%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

di(p-tolyl)borinic acid
66117-64-4

di(p-tolyl)borinic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With NiCl2(Tris-(4-methoxy-phenyl)-phosphin)2; potassium phosphate tribasic trihydrate; P(p-CH3OC6H4)3 In toluene at 110℃; for 5h; Reagent/catalyst; Inert atmosphere;98%
With triphenyl phosphite; potassium phosphate tribasic trihydrate; N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene hydrochloride; palladium diacetate In tert-butyl alcohol at 80℃; for 16h; Inert atmosphere;97%
With bis(triphenylphosphine)nickel(II) chloride; potassium phosphate tribasic trihydrate; 1-n-butyl-3-methylimidazolim bromide In toluene at 110℃; for 6h; Inert atmosphere;97%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

potassium (4-methylphenyl)trifluoroborate

potassium (4-methylphenyl)trifluoroborate

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With 5%-palladium/activated carbon; oxygen; potassium carbonate In ethanol; water at 80℃; for 0.416667h; Suzuki-Miyaura Coupling;97%
With palladium diacetate; potassium carbonate In ethanol; water at 25℃; for 2h; Suzuki-Miyaura Coupling;95%
4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole
84392-32-5

4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With pyridine; trichlorophosphate at 100℃; for 3h;96%
With pyridine; trichlorophosphate at 10 - 100℃; for 3h;
Multi-step reaction with 2 steps
1: hydrogenchloride
2: thionyl chloride / water; toluene
View Scheme
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With 1,2-dimethoxyethane; Cl4Li2Pd; 1,3-bis-(diphenylphosphino)propane95%
With 1,2-dimethoxyethane; lithium chloride; manganese(ll) chloride; 1,3-bis-(diphenylphosphino)propane; palladium dichloride In tetrahydrofuran at 20℃; for 1 - 3.5h;95%
With 1,2-dimethoxyethane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate94%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With palladium diacetate; XPhos In toluene at 120℃; for 40h; Inert atmosphere; Sealed tube;95%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

p-tolylzinc(II) chloride
90252-89-4

p-tolylzinc(II) chloride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With tetrakis(triphenylphosphine)nickel(0) Negishi-like coupling reaction;94%
With C26H24ClN2NiP*0.1C7H8 In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Negishi Coupling; Schlenk technique; Inert atmosphere;92%
tris(dibenzylideneacetone)dipalladium (0); tris[tert-butyl]phosphonium tetrafluoroborate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 175℃; for 0.166667h; Negishi cross-coupling; microwave irradiation;90%
With C21H18N8Ni2O(2+)*2F6P(1-) In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20 - 80℃; Negishi coupling reaction;88%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

para-chlorotoluene
106-43-4

para-chlorotoluene

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
Stage #1: para-chlorotoluene With magnesium In tetrahydrofuran at 50 - 70℃; Inert atmosphere;
Stage #2: 2-Chlorobenzonitrile With magnesium chloride In tetrahydrofuran at 5 - 10℃; Inert atmosphere;
93.6%
PdCl2/dppp

PdCl2/dppp

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; 1,2-dimethoxyethane93%
p-toluidine
106-49-0

p-toluidine

benzonitrile
100-47-0

benzonitrile

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
Stage #1: p-toluidine With toluene-4-sulfonic acid; sodium nitrite In water at 25℃;
Stage #2: benzonitrile With copper(l) iodide; sodium acetate In water at 80℃; Solvent; Temperature; Reagent/catalyst;
92.1%
Stage #1: p-toluidine With tetrafluoroboric acid; sodium nitrite In water at 0 - 5℃; for 0.5h; Inert atmosphere;
Stage #2: benzonitrile With Tetrakis(dimethylamino)ethylen; 9-methylamino-1-ethoxyphenalenium tetrafluoroborate In dimethyl sulfoxide at 20℃; for 12h; Glovebox; Inert atmosphere; regioselective reaction;
50%
4'-methylbiphenyl-2-carboxime

4'-methylbiphenyl-2-carboxime

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With phosphorus pentoxide In tetrahydrofuran at 20℃; for 1h;92%
4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; TPGS-750-M; triethylamine In water at 20℃; Inert atmosphere;92%
With Pd/Nb2O5; potassium carbonate In ethanol; water at 120℃; for 2h; Suzuki-Miyaura cross-coupling; Microwave irradiation;
2-cyanophenyl 1H-imidazole-1-sulfonate

2-cyanophenyl 1H-imidazole-1-sulfonate

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With C26H16Cl6N2O2Pd2; tetrabutylammomium bromide; potassium hydroxide In methanol; water at 110℃; for 0.333333h; Suzuki coupling; Microwave irradiation;92%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

tributyl(p-tolyl)stannane
31614-66-1

tributyl(p-tolyl)stannane

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; lithium chloride In N,N-dimethyl-formamide Inert atmosphere;92%
4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

4-methyl-8-(4-methylphenyl)-2,6-dioxotetrahydro[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-4-ium-8-uide

2-cyanobenzene-1-sulfonyl fluoride
395-46-0

2-cyanobenzene-1-sulfonyl fluoride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; diisopropylamine In ethanol; water at 25℃; for 4h;92%
o-(p-tolyl)benzaldoxime

o-(p-tolyl)benzaldoxime

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With formic acid91%
2-iodobenzonitrile
4387-36-4

2-iodobenzonitrile

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With potassium phosphate Reflux;90.4%
With sodium carbonate In water; ethyl acetate; isopropyl alcohol at 50℃; for 0.00111111h; Suzuki-Miyaura coupling; Microchannel flow reactor;99 %Chromat.
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In N,N-dimethyl-formamide for 6h; Suzuki Coupling; Inert atmosphere; Reflux;
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
Stage #1: 2-Chlorobenzonitrile With bis(triphenylphosphine)nickel(II) chloride; methoxydichlorozinc acid In tetrahydrofuran at 20℃; for 0.25h;
Stage #2: 4-tolylmagnesium chloride In tetrahydrofuran at 28 - 32℃; Inert atmosphere;
90%
Stage #1: 2-Chlorobenzonitrile With chloro-trimethyl-silane; manganese(ll) chloride In tetrahydrofuran at -5 - 0℃; Inert atmosphere; Green chemistry;
Stage #2: 4-tolylmagnesium chloride In tetrahydrofuran at -5 - 25℃; for 9h; Inert atmosphere; Green chemistry;
86%
With nickel; zinc(II) chloride In tetrahydrofuran at 50 - 60℃; Product distribution; various double metal catalysts, various yield of products;
With iron(III) chloride In tetrahydrofuran at 0 - 130℃; for 3h; Temperature; Grignard Reaction; Large scale;6.93 kg
sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

2-<(trifluoromethanesulfonyl)oxy>benzonitrile
138313-23-2

2-<(trifluoromethanesulfonyl)oxy>benzonitrile

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With palladium diacetate; XPhos In toluene at 120℃; for 24h; Sealed tube; Inert atmosphere;90%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With palladium diacetate; XPhos In toluene at 120℃; for 40h; Inert atmosphere; Sealed tube;90%
With caesium carbonate; palladium dichloride In N,N-dimethyl-formamide at 185℃; for 20h; Inert atmosphere; Sealed tube;54%
4-tolyl iodide
624-31-7

4-tolyl iodide

2-Cyanophenylboronic acid
138642-62-3

2-Cyanophenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With Ti0.97Pd0.03O1.97; potassium carbonate In water at 100℃; for 6h; Suzuki-Miyaura Coupling;89%
NiCl2 (Ph3 P)2

NiCl2 (Ph3 P)2

ethyl acetate n-hexane

ethyl acetate n-hexane

para-bromotoluene
106-38-7

para-bromotoluene

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; pentane88%
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; pentane88%
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; pentane88%
NiCl2 (Ph3 P)2

NiCl2 (Ph3 P)2

para-bromotoluene
106-38-7

para-bromotoluene

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; pentane88%
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; hexane; ethyl acetate; pentane
With hydrogenchloride; tert.-butyl lithium; zinc(II) chloride In tetrahydrofuran; hexane; ethyl acetate; pentane
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

palladium dichloride

palladium dichloride

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With triphenylphosphine In tetrahydrofuran; water; toluene88%
para-bromotoluene
106-38-7

para-bromotoluene

2-(cyano)halobenzene

2-(cyano)halobenzene

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
Stage #1: para-bromotoluene With chloro-trimethyl-silane; ethylene dibromide; lithium chloride; zinc In tetrahydrofuran at 25℃; for 24h; Knochel Zinc Vinyl Coupling; Inert atmosphere;
Stage #2: 2-(cyano)halobenzene With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride In tetrahydrofuran at 25℃; for 1h; Knochel Zinc Vinyl Coupling; Inert atmosphere; Schlenk technique;
88%
Pd2 (dba)3

Pd2 (dba)3

2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
ConditionsYield
With cesium fluoride In 1,4-dioxane87%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl
120568-11-8

2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl

Conditions
ConditionsYield
With trimethylsilylazide; tetrabutyl ammonium fluoride at 120℃; for 36h;97%
With sodium azide; zinc(II) chloride In N,N-dimethyl-formamide for 36h; Heating;96%
With sodium azide; triethylamine hydrochloride In N,N-dimethyl-formamide at 35℃; for 3h; Temperature; Sonication;96%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

methyl 2-diazo-2-(fluorosulfonyl)acetate

methyl 2-diazo-2-(fluorosulfonyl)acetate

5-methoxy-2-(4'-methyl-[1,1'-biphenyl]-2-yl)oxazole-4-sulfonyl fluoride

5-methoxy-2-(4'-methyl-[1,1'-biphenyl]-2-yl)oxazole-4-sulfonyl fluoride

Conditions
ConditionsYield
Stage #1: 2-Cyano-4'-methylbiphenyl With dirhodium tetraacetate In chloroform at 70℃;
Stage #2: methyl 2-diazo-2-(fluorosulfonyl)acetate In chloroform at 70℃; for 12h;
97%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane96%
With bromine In water; 1,2-dichloro-ethane at 84℃; for 0.25h; Temperature; Solvent; Irradiation; Flow reactor;96.3%
With bromine In 1,2-dichloro-ethane at 70℃; for 0.5h; Reagent/catalyst; Temperature; Time; Irradiation;94%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

5-<4'-Methyl-1,1'-biphenyl-2-yl>-1H-tetrazole
120568-11-8

5-<4'-Methyl-1,1'-biphenyl-2-yl>-1H-tetrazole

Conditions
ConditionsYield
Stage #1: 2-Cyano-4'-methylbiphenyl With sodium azide; zinc(II) chloride In N,N-dimethyl-formamide for 36h; Heating;
Stage #2: With hydrogenchloride In N,N-dimethyl-formamide for 1h; cooling; Further stages.;
96%
With hydrogenchloride; sodium azide; triethylamine hydrochloride In 5,5-dimethyl-1,3-cyclohexadiene at 28 - 142℃; for 29h;87%
Stage #1: 2-Cyano-4'-methylbiphenyl With sodium azide In N,N-dimethyl-formamide at 135℃; for 37h;
Stage #2: With hydrogenchloride In water; ethyl acetate; N,N-dimethyl-formamide
82%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4-Methylbiphenyl-2'-carboxamidoxime
147403-93-8

4-Methylbiphenyl-2'-carboxamidoxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride In methanol; dimethyl sulfoxide96%
With hydroxylamine hydrochloride; triethylamine In dimethyl sulfoxide at 80 - 85℃; for 24h; Reagent/catalyst; Solvent;89.6%
aqueous hydrochloric acid(pH 1)

aqueous hydrochloric acid(pH 1)

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl
120568-11-8

2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl

Conditions
ConditionsYield
Zinc chloride In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; N,N-dimethyl-formamide94%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

o-(p-tolyl)-benzylamine hydrochloride
1536169-09-1

o-(p-tolyl)-benzylamine hydrochloride

Conditions
ConditionsYield
Stage #1: 2-Cyano-4'-methylbiphenyl With C46H178O41Si42; titanium(IV)isopropoxide In toluene at 60℃; for 9h; Inert atmosphere;
Stage #2: With hydrogenchloride; water In toluene at 20℃; for 9h; Inert atmosphere;
94%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

o-tolylbenzoic acid
7148-03-0

o-tolylbenzoic acid

Conditions
ConditionsYield
With potassium hydroxide In ethylene glycol at 170℃; for 48h;93%
With sodium hydroxide In methanol; water at 80℃; for 10h; Temperature; Large scale;91.06%
Stage #1: 2-Cyano-4'-methylbiphenyl With sodium hydroxide In ethylene glycol at 170℃; for 8h;
Stage #2: With hydrogenchloride In water; toluene
90.4%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4-methyl-2'-thiocarboxamido-1,1'-biphenyl
162356-74-3

4-methyl-2'-thiocarboxamido-1,1'-biphenyl

Conditions
ConditionsYield
With hydrogenchloride In methanol92%
Stage #1: 2-Cyano-4'-methylbiphenyl With magnesium(II) chloride hexahydrate; sodium monohydrogensulphide hydrate In water; N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: With hydrogenchloride In water for 0.333333h;
92.1%
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