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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Manufacturer/High quality/Best price/In stock

Cas:114772-40-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 4'-Bromomethyl Biphenyl-2-Carboxylic Acid tert-butyl ester 114772-40-6 Producer

Cas:114772-40-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

α-Bromo-2-(p-tolyl)-benzoic acid tert-butyl ester

Cas:114772-40-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Basic information Product Name: tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Synonyms: 4'-BROMOME

TIANFU-CHEM tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate 114772-40-6

Cas:114772-40-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate CAS 114772-40-6

Cas:114772-40-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 114772-40-6 with best quality

Cas:114772-40-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

[1,1'-Biphenyl]-2-carboxylicacid, 4'-(bromomethyl)-, 1,1-dimethylethyl ester 114772-40-6

Cas:114772-40-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate CAS:114772-40-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, special

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate CAS:114772-40-6

Cas:114772-40-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylat

Cas:114772-40-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

[1,1'-Biphenyl]-2-carboxylicacid, 4'-(bromomethyl)-, 1,1-dimethylethyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

TERT-BUTYL 4'-(BROMOMETHYL)BIPHENYL-2-CARBOXYLATE CAS 114772-40-6

Cas:114772-40-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

[1,1'-Biphenyl]-2-carboxylicacid, 4'-(bromomethyl)-, 1,1-dimethylethyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colorless liquid Storage:Well-sealed and put in dry and cool conditions. Protected from direct sunlight or high temperature. Package:as per your request Application:Used as Pha

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Telmisartan EP Impurity H (Telmisartan Bromo t-Butyl Ester)

Cas:114772-40-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Basic information Product Name: tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Synonyms: 4'-BROMOMETHYL-BIPHENYL-2-CARBOXYLIC ACID TERT-BUTYL ESTER;4-BROMOMETHYL BIPHENYL-2-CARBO

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Tert-butyl-4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Luyunjia Chemistry Xiamen Limited

Luyunjia Chemistry Xiamen Limited is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic drug. and has a h

hight quality Tertiary Butyl-4-(Bromo Methyl )-2-Bi Phenyl Carboxylate

Cas:114772-40-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

4'-Bromomethyl Biphenyl-2-Carboxylic Acid tert-butyl esterAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

4'-Bromomethyl Biphenyl-2-Carboxylic Acid tert-butyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Tert-Butyl-4'-bromomethyl-2-biphenylcarboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4'-Bromomethyl Biphenyl-2-Carboxylic Acid tert-butyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

tert-Butyl 4'-(broMoMethyl)-[1,1'-biphenyl]-2-carboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Tert-Butyl 4'-(Bromomethyl)Biphenyl-2-Carboxylate

Cas:114772-40-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

4'-Bromomethyl Biphenyl-2-Carboxylic Acid tert-butyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Koning Pharmchem Co., Ltd.

KONING PHARMCHEM CO., LTD. has committed itself to a strategy of providing a unique service for companies involved in the manufacture of pharmaceuticals, healthcare products, food, cosmetics and other fine chemicals. Our products including but not li

4'-Bromomethyl Biphenyl-2-Carboxyli Acid tert-butyl ester

Cas:114772-40-6

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

tert-butyl 4'-methyl-2-biphenylcarboxylate
114772-36-0

tert-butyl 4'-methyl-2-biphenylcarboxylate

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With azobisisobutyronitrile; sodium acetate In acetic acid methyl ester; water; isopropyl alcohol; acetone85%
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 4.5h; Heating;82%
With N-Bromosuccinimide; azobisisobutyronitrile; sodium acetate In acetic acid methyl ester; water; isopropyl alcohol80%
biphenyl-2-carboxylic acid tert-butyl ester

biphenyl-2-carboxylic acid tert-butyl ester

formaldehyd
50-00-0

formaldehyd

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: biphenyl-2-carboxylic acid tert-butyl ester; formaldehyd With zinc dibromide In dichloromethane at 30 - 35℃; for 0.333333h;
Stage #2: With phosphorus pentabromide In tetrachloromethane; dichloromethane
81.9%
tert-butyl 2-bromobenzoate
55666-42-7

tert-butyl 2-bromobenzoate

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / tetrakis(triphenylphosphine)palladium, 2M aq. sodium carbonate / toluene; ethanol / 4 h / Heating
2: 82 percent / NBS, AIBN / CCl4 / 4.5 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 0.67 h / 100 °C / Sealed vial
2: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 2 h / 100 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium carbonate / isopropyl alcohol / 0.5 h / Inert atmosphere
1.2: 40 h / 90 °C / Inert atmosphere
2.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / Reflux
View Scheme
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane; water / 0.75 h / 100 °C / Sealed tube
2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 2 h / 100 °C
View Scheme
4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / tetrakis(triphenylphosphine)palladium, 2M aq. sodium carbonate / toluene; ethanol / 4 h / Heating
2: 82 percent / NBS, AIBN / CCl4 / 4.5 h / Heating
View Scheme
2-bromobenzoic-acid
88-65-3

2-bromobenzoic-acid

copper powder

copper powder

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) N,N'-carbonyldiimidazole, 2.) DBU / 1.) DMF, 40 deg C, 1 h, 2.) DMF, a) 40 deg C, 24 h, b) 50 deg C, 16 h
2: 95 percent / tetrakis(triphenylphosphine)palladium, 2M aq. sodium carbonate / toluene; ethanol / 4 h / Heating
3: 82 percent / NBS, AIBN / CCl4 / 4.5 h / Heating
View Scheme
o-tolylbenzoic acid
7148-03-0

o-tolylbenzoic acid

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 94 percent / sulfuric acid / diethyl ether / 25 °C
2: NBS, AIBN / CCl4 / Heating
View Scheme
Multi-step reaction with 3 steps
1: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
2: tetrahydrofuran / 1 h / 25 °C
3: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: thionyl chloride / 5.5 h / 20 °C / Inert atmosphere
2: tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere
3: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 6 h / Inert atmosphere; Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: oxalyl dichloride / dichloromethane / 3 h / 0 - 20 °C
1.2: 1 h / 10 - 20 °C
2.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / Reflux
View Scheme
methyl 4'-methylbiphenyl-2-carboxylate
114772-34-8

methyl 4'-methylbiphenyl-2-carboxylate

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / NaOH / H2O; methanol / Heating
2: 94 percent / sulfuric acid / diethyl ether / 25 °C
3: NBS, AIBN / CCl4 / Heating
View Scheme
2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
57598-33-1

2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: tetrahydrofuran / 2 h / 20 °C
2: 88 percent / 4.5 N aq. HCl / 12 h / Heating
3: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
4: tetrahydrofuran / 1 h / 25 °C
5: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
4'-methylbiphenyl-2-carboxylic acid chloride
114772-35-9

4'-methylbiphenyl-2-carboxylic acid chloride

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran / 1 h / 25 °C
2: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere
2: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 6 h / Inert atmosphere; Reflux
View Scheme
N-(2-hydroxy-1,1-dimethyl)-2-methoxybenzamide
74201-13-1

N-(2-hydroxy-1,1-dimethyl)-2-methoxybenzamide

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: thionyl chloride / 1 h / 25 °C
2: tetrahydrofuran / 2 h / 20 °C
3: 88 percent / 4.5 N aq. HCl / 12 h / Heating
4: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
5: tetrahydrofuran / 1 h / 25 °C
6: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole
84392-32-5

4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 88 percent / 4.5 N aq. HCl / 12 h / Heating
2: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
3: tetrahydrofuran / 1 h / 25 °C
4: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
2-Methoxybenzoic acid
579-75-9

2-Methoxybenzoic acid

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 95 percent / thionyl chloride / 18 h / 20 °C
2: CH2Cl2 / 2 h / 20 °C
3: thionyl chloride / 1 h / 25 °C
4: tetrahydrofuran / 2 h / 20 °C
5: 88 percent / 4.5 N aq. HCl / 12 h / Heating
6: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
7: tetrahydrofuran / 1 h / 25 °C
8: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
2-Methoxybenzoyl chloride
21615-34-9

2-Methoxybenzoyl chloride

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: CH2Cl2 / 2 h / 20 °C
2: thionyl chloride / 1 h / 25 °C
3: tetrahydrofuran / 2 h / 20 °C
4: 88 percent / 4.5 N aq. HCl / 12 h / Heating
5: oxalyl chloride / CH2Cl2 / 3 h / 25 °C
6: tetrahydrofuran / 1 h / 25 °C
7: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
C18H20O3
145319-09-1

C18H20O3

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With N-Bromosuccinimide; triphenylphosphine In dichloromethane at -78 - 20℃;
tert-butyl 4'-methyl-2-biphenylcarboxylate
114772-36-0

tert-butyl 4'-methyl-2-biphenylcarboxylate

A

4'-dibromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
901768-33-0

4'-dibromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

B

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 5h; Reflux; Inert atmosphere;
benzonitrile
100-47-0

benzonitrile

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: n-butyllithium; 2,2,6,6-tetramethylpiperidinyl-lithium / tetrahydrofuran; hexane / 0.08 h / -78 - -10 °C / Inert atmosphere
1.2: 5 h / -78 - 20 °C / Inert atmosphere
2.1: toluene / 20 °C
3.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; toluene / 4 h / 100 °C / Inert atmosphere
4.1: hydrogenchloride; water / 12 h / Reflux
5.1: oxalyl dichloride / dichloromethane / 3 h / 0 - 20 °C
5.2: 1 h / 10 - 20 °C
6.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / Reflux
View Scheme
C13H18BNO2

C13H18BNO2

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: toluene / 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; toluene / 4 h / 100 °C / Inert atmosphere
3.1: hydrogenchloride; water / 12 h / Reflux
4.1: oxalyl dichloride / dichloromethane / 3 h / 0 - 20 °C
4.2: 1 h / 10 - 20 °C
5.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / Reflux
View Scheme
2-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-benzonitrile
214360-47-1

2-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-benzonitrile

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; toluene / 4 h / 100 °C / Inert atmosphere
2.1: hydrogenchloride; water / 12 h / Reflux
3.1: oxalyl dichloride / dichloromethane / 3 h / 0 - 20 °C
3.2: 1 h / 10 - 20 °C
4.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / Reflux
View Scheme
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogenchloride; water / 12 h / Reflux
2.1: oxalyl dichloride / dichloromethane / 3 h / 0 - 20 °C
2.2: 1 h / 10 - 20 °C
3.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / Reflux
View Scheme
2-bromobenzoic-acid
88-65-3

2-bromobenzoic-acid

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dicyclohexyl-carbodiimide / dmap / dichloromethane / 20 h / 20 °C / Inert atmosphere
2: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 0.67 h / 100 °C / Sealed vial
3: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 2 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 6 h / 0 - 20 °C
2.1: sodium carbonate / isopropyl alcohol / 0.5 h / Inert atmosphere
2.2: 40 h / 90 °C / Inert atmosphere
3.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / Reflux
View Scheme
Multi-step reaction with 3 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 h / 20 °C / Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane; water / 0.75 h / 100 °C / Sealed tube
3: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 2 h / 100 °C
View Scheme
2-Biphenylcarboxylic acid
947-84-2

2-Biphenylcarboxylic acid

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid / 6 h / Reflux
2: zinc dibromide / dichloromethane / 0.33 h / 30 - 35 °C
View Scheme
para-bromotoluene
106-38-7

para-bromotoluene

tert-butyl 2-iodobenzoate
110349-26-3

tert-butyl 2-iodobenzoate

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride; tert.-butyl lithium / zinc(II) chloride / tetrahydrofuran; hexane; ethyl acetate; pentane
View Scheme
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4'-(Azidomethyl)[1,1'-biphenyl]-2-carboxylic acid,1,1-dimethylethyl ester
139476-12-3

4'-(Azidomethyl)[1,1'-biphenyl]-2-carboxylic acid,1,1-dimethylethyl ester

Conditions
ConditionsYield
With sodium azide In N,N-dimethyl-formamide for 24h; Ambient temperature;100%
With sodium azide In N,N-dimethyl-formamide at 100℃; for 1.5h; Inert atmosphere;100%
In N-methyl-acetamide; water
N-BOC-1,2-diaminoethane
57260-73-8

N-BOC-1,2-diaminoethane

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4'-[(2-t-butoxycarbonylaminoethylamino)methyl]biphenyl-2-carboxylic acid t-butyl ester
1043607-99-3

4'-[(2-t-butoxycarbonylaminoethylamino)methyl]biphenyl-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃;98.4%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

3-[2(R)-benzyloxypropyl]amino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(R)-yl]-butanamide
145486-47-1

3-[2(R)-benzyloxypropyl]amino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(R)-yl]-butanamide

t-Butyl 4'-[[3(R)-[[3-[2(R)-benzyloxypropyl]amino-3-methyl-1-oxobutyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl]methyl][1,1'-biphenyl]-2-carboxylate
170277-86-8

t-Butyl 4'-[[3(R)-[[3-[2(R)-benzyloxypropyl]amino-3-methyl-1-oxobutyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl]methyl][1,1'-biphenyl]-2-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 1.5h; Ambient temperature;92%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

6-butyl-4-chloro-1,2-dihydro-2,2-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester
142385-38-4

6-butyl-4-chloro-1,2-dihydro-2,2-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester

2-butyl-1-<2'-<(1,1-dimethylethoxy)carbonyl><1,1'-biphenyl>-4-yl>-6-chloro-1,4-dihydro-4,4-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester
142385-39-5

2-butyl-1-<2'-<(1,1-dimethylethoxy)carbonyl><1,1'-biphenyl>-4-yl>-6-chloro-1,4-dihydro-4,4-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide for 5h; Ambient temperature;91.1%
allyl 2,3-dimethyl-1H-indole-5-carboxylate
1266458-65-4

allyl 2,3-dimethyl-1H-indole-5-carboxylate

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

allyl 1-((2'-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylate

allyl 1-((2'-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylate

Conditions
ConditionsYield
Stage #1: allyl 2,3-dimethyl-1H-indole-5-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere;
Stage #2: 4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester In N,N-dimethyl-formamide; mineral oil at 20℃; Inert atmosphere;
90%
2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde
83857-96-9

2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4’-(2-butyl-4-chloro-5-formylimidazol-1-ylmethyl)biphenyl-2-carboxylic acid t-butyl ester
133694-34-5

4’-(2-butyl-4-chloro-5-formylimidazol-1-ylmethyl)biphenyl-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere;89%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;
2-methylthioquinazolin-4(3H)-one
54855-81-1

2-methylthioquinazolin-4(3H)-one

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4'-(2-methylsulfanyl-4-oxo-4H-quinazolin-3-ylmethyl)biphenyl-2-carboxylic acid tert-butyl ester

4'-(2-methylsulfanyl-4-oxo-4H-quinazolin-3-ylmethyl)biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 2-methylthioquinazolin-4(3H)-one With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: 4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester In dimethyl sulfoxide at 20℃; for 19h;
88%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride

2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride

tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate
138401-20-4

tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 0.0180556h; microwave irradiation;88%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

3-butyl-1,2,4-oxadiazol-5(4H)-one
150694-23-8

3-butyl-1,2,4-oxadiazol-5(4H)-one

4'-<<3-butyl-5-oxo-1,2,4-oxadiazol-4(5H)-yl>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester
150694-24-9

4'-<<3-butyl-5-oxo-1,2,4-oxadiazol-4(5H)-yl>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 17h;87%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4-butyl-1-<<2-(trimethylsilyl)ethoxy>methyl>imidazole

4-butyl-1-<<2-(trimethylsilyl)ethoxy>methyl>imidazole

5-butyl-1-[[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl]-3-[(2-(trimethylsilyl)ethoxy)methyl]-1H-imidazolium bromide
1400934-15-7

5-butyl-1-[[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl]-3-[(2-(trimethylsilyl)ethoxy)methyl]-1H-imidazolium bromide

Conditions
ConditionsYield
In acetonitrile for 3h; Reflux; Inert atmosphere;87%
2-butyl-1H-imidazole
50790-93-7

2-butyl-1H-imidazole

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

1-<<2'-(tert-butoxycarbonyl)biphenyl-4-yl>methyl>-2-butylimidazole

1-<<2'-(tert-butoxycarbonyl)biphenyl-4-yl>methyl>-2-butylimidazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide 1.) RT, 30 min, 2.) RT, overnight;86%
With sodium hydride In N,N-dimethyl-formamide86%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole
152628-02-9

2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole

tert-butyl 4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate
144702-26-1

tert-butyl 4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate

Conditions
ConditionsYield
With potassium tert-butylate In 1-methyl-pyrrolidin-2-one at 10℃; for 4h;86%
With sodium In methanol at 70℃; Reagent/catalyst; Temperature; Solvent;71%
With potassium tert-butylate In N,N-dimethyl acetamide at 75 - 80℃; for 3h; Inert atmosphere;70%
With potassium tert-butylate 1.) DMSO, RT, 30 min, 2.) DMSO, 14 h; Multistep reaction;
With potassium tert-butylate In dimethyl sulfoxide at 25 - 30℃; for 3.5h; Product distribution / selectivity;
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate
177478-49-8

methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate

methyl 1-((2'-(tert-butoxycarbonyl)-[1,1'-biphenyl]-4-yl)methyl)-1,2,3,4-tetrahydroquinoline-6-carboxylate

methyl 1-((2'-(tert-butoxycarbonyl)-[1,1'-biphenyl]-4-yl)methyl)-1,2,3,4-tetrahydroquinoline-6-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 12h;85%
2-butyl-1H-imidazole
50790-93-7

2-butyl-1H-imidazole

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

2-butyl-N,N'-bis{[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl}imidazolium bromide
1431152-75-8

2-butyl-N,N'-bis{[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl}imidazolium bromide

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h; Inert atmosphere;84%
potassium phtalimide
1074-82-4

potassium phtalimide

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

N-[[2'-(t-Butoxycarbonyl)biphenyl-4-yl]-methyl]phthalimide
133690-72-9

N-[[2'-(t-Butoxycarbonyl)biphenyl-4-yl]-methyl]phthalimide

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 7h; Ambient temperature;82%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4-n-Butyl-imidazole
146953-86-8

4-n-Butyl-imidazole

4-butyl-N,N'-bis{[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl}imidazolium bromide
1431152-06-5

4-butyl-N,N'-bis{[2'-(tert-butoxycarbonyl)biphenyl-4-yl]methyl}imidazolium bromide

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 8h; Inert atmosphere;82%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

3-butyl-6-(phenylethyl)-4H-1,2,4-oxadiazin-5(6H)-one
150694-39-6

3-butyl-6-(phenylethyl)-4H-1,2,4-oxadiazin-5(6H)-one

4'-<<3-butyl-5,6-dihydro-5-oxo-6-(phenylethyl)-4H-1,2,4-oxadiazin-4-yl>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester
150694-40-9

4'-<<3-butyl-5,6-dihydro-5-oxo-6-(phenylethyl)-4H-1,2,4-oxadiazin-4-yl>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 19h;81%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4-<2'-<(1,1-dimethylethoxy)carbonyl>phenyl>benzaldehyde
145319-08-0

4-<2'-<(1,1-dimethylethoxy)carbonyl>phenyl>benzaldehyde

Conditions
ConditionsYield
With hexamethylenetetramine; water; sodium dodecyl-sulfate; lanthanum(lll) triflate at 100℃; for 4.5h; Sommelet Aldehyde Synthesis; Green chemistry;80%
With silver tetrafluoroborate; chromium chlorochromate; sodium hydrogencarbonate 1.) dimethyl sulfoxide, RT, 6 h 2.) dichloromethane, RT, 1 h; Yield given. Multistep reaction;
3-(2-butyl-1H-imidazol-4-yl)propan-1-ol

3-(2-butyl-1H-imidazol-4-yl)propan-1-ol

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

A

4'-[2-butyl-4-(3-hydroxypropyl)imidazol-1-ylmethyl]biphenyl-2-carboxylic acid tert-butyl ester

4'-[2-butyl-4-(3-hydroxypropyl)imidazol-1-ylmethyl]biphenyl-2-carboxylic acid tert-butyl ester

B

4'-[2-butyl-5-(3-hydroxypropyl)imidazol-1-ylmethyl]biphenyl-2-carboxylic acid tert-butyl ester

4'-[2-butyl-5-(3-hydroxypropyl)imidazol-1-ylmethyl]biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 18h; Inert atmosphere;A 80%
B 6%
8-Butyl-1,3-dimethyl-1,2,3,6-tetrahydro-2,6-dioxopurine
35873-40-6

8-Butyl-1,3-dimethyl-1,2,3,6-tetrahydro-2,6-dioxopurine

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

7-(2'-t-butoxycarbonylbiphenyl-4-yl)methyl-8-n-butyl-1,3-dimethylxanthine

7-(2'-t-butoxycarbonylbiphenyl-4-yl)methyl-8-n-butyl-1,3-dimethylxanthine

Conditions
ConditionsYield
In N,N-dimethyl-formamide; mineral oil78.7%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

3-butyl-6-methyl-4H-1,2,4-oxadiazin-5(6H)-one
150694-19-2

3-butyl-6-methyl-4H-1,2,4-oxadiazin-5(6H)-one

4'-<(3-butyl-5,6-dihydro-6-methyl-5-oxo-4H-1,2,4-oxadiazin-4-yl)methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester
150694-20-5

4'-<(3-butyl-5,6-dihydro-6-methyl-5-oxo-4H-1,2,4-oxadiazin-4-yl)methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 19h;78%
sodium cyanide
143-33-9

sodium cyanide

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4-<2'-(tert-butoxycarbonyl)phenyl>benzyl cyanide
150871-50-4

4-<2'-(tert-butoxycarbonyl)phenyl>benzyl cyanide

Conditions
ConditionsYield
In dimethyl sulfoxide 1.) 45-50 deg C, 30 min, 2.) RT, 2.5 h;76%
2-hydroxymethyl-2,5,7,8-tetramethyl-chroman-6-ol
79907-49-6

2-hydroxymethyl-2,5,7,8-tetramethyl-chroman-6-ol

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4'-(2-hydroxymethyl-2,5,7,8-tetramethylchroman-6-yloxymethyl)biphenyl-2-carboxylic acid tert-butyl ester

4'-(2-hydroxymethyl-2,5,7,8-tetramethylchroman-6-yloxymethyl)biphenyl-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 48h; Inert atmosphere;76%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

3-butyl-6-phenyl-4H-1,2,4-oxadiazin-5(6H)-one
150758-58-0

3-butyl-6-phenyl-4H-1,2,4-oxadiazin-5(6H)-one

4'-<<(oxophenylacetyl)amino>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester

4'-<<(oxophenylacetyl)amino>methyl><1,1'-biphenyl>-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 25℃; for 1h;75%
6-hydroxymethyl-4-methyl-2-propyl-1H-benzimidazole
1092951-05-7

6-hydroxymethyl-4-methyl-2-propyl-1H-benzimidazole

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

4'-(6-hydroxymethyl-4-methyl-2-propyl-1H-benzimidazol-1-ylmethyl)biphenyl-2-carboxylic acid t-butyl ester
1190092-28-4

4'-(6-hydroxymethyl-4-methyl-2-propyl-1H-benzimidazol-1-ylmethyl)biphenyl-2-carboxylic acid t-butyl ester

Conditions
ConditionsYield
With potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate In acetonitrile at 55℃; for 5h; Inert atmosphere;73.5%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;10.61g
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole
152628-02-9

2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole

tert butyl 4'-[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-ylmethyl]biphenyl-2-carboxylate hydrochloride
921208-39-1

tert butyl 4'-[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-ylmethyl]biphenyl-2-carboxylate hydrochloride

Conditions
ConditionsYield
Stage #1: 4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester; 2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole With potassium hydroxide In water; acetone at 0 - 30℃; for 6.5h;
Stage #2: With hydrogenchloride In dichloromethane; water at 20 - 25℃; pH=1.8;
73%
4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester
114772-40-6

4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester

2-butyl-1,6-dihydro-4,6-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester
142385-35-1

2-butyl-1,6-dihydro-4,6-dimethyl-5-pyrimidinecarboxylic acid, ethyl ester

2-butyl-1-<2'-<(1,1'-dimethylethoxy)carbonyl><1,1'-biphenyl>-4-yl>-1,6-dihydro-4,6-dimethyl-5-pyrimidinecarboxylic acid
142385-36-2

2-butyl-1-<2'-<(1,1'-dimethylethoxy)carbonyl><1,1'-biphenyl>-4-yl>-1,6-dihydro-4,6-dimethyl-5-pyrimidinecarboxylic acid

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide Ambient temperature;72.5%

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