Products

Refine

Country

Business Type

Certificate

Display

AstaTech ( Chengdu) BioPharmaceutical Corp.

Chengdu AstaTech Chemical Technology Co., Ltd. is a wholly-owned subsidiary of AstaTech (Chengdu) BioPharmaceutical Co., Ltd. It has overall accountability for AstaTech’s product list and sales and promotion of chemical reagents in China. The company

4-(Bromomethyl)-2′-cyanobiphenyl

Cas:114772-54-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Bromomethyl-2-cyanobiphenyl Manufacturer/High quality/Best price/In stock

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Bromomethyl-2-Cyanobiphenyl supplier in China

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications 4'-bromomethyl-2-cyanobiphenyl CAS:114772-54-2

Cas:114772-54-2

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product Name 4-Bromomethyl-2-cyanobiphenyl CAS No. 114772-54-2 Appearance White powder Assay ≥99% Capacity 200mt/year Min.packing 100g

4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Gram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Think Chemical Co. Ltd

4-Bromomethyl-2-cyanobiphenyl CAS No.:114772-54-2 Name 4-Bromomethyl-2-cyanobiphenyl Synonyms 4'-Bromomethyl-2-biphenylcarbonitrile Molecular Structure Molecular Formula C14H

4-Bromomethyl-2-cyanobiphenyl CAS No.:114772-54-2

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

114772-54-24-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4'-Bromomethylbiphenyl-2-carbonitrile

Cas:114772-54-2

Min.Order:1

Negotiable

Type:Other

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Bromomethyl-2'-Cyanobiphene

Cas:114772-54-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

4-Bromomethyl-2-cyanobiphenyl Manufacturer/High quality/Best price/In stock CAS NO.114772-54-2

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Bromomethyl)-2'-cyanobiphenyl

Cas:114772-54-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 4-Bromomethyl-2-cyanobiphenyl Synonyms: 4-BroMoMethyl-2-cyanophenyl;4-BroMoMethyl-2-cyanobiphenyl, 98% 5GR;4-(2-Cyanophenyl)benzyl BroMide;4'-Bromomethylbiphenyl-2-carbonitrile 2-Cyano-4'-bromomethylbiphenyl;Br-OT

114772-54-2 4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

4-Bromomethyl-2-Cyanobiphenyl CAS 114772-54-2

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 114772-54-2 with best quality

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

4-Bromomethyl-2-cyanobiphenyl CAS114772-54-2

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4-Bromomethyl-2-cyanobiphenyl/ LIDE PHARMA- Factory supply / Best price

Cas:114772-54-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Name: 4-Bromomethyl-2-Cyanobiphenyl Synonyms: 4-Bromomethyl-2-Biphenylcarbonitrile CAS:114772-54-2 MF: C14H10BrN Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Pharmaceutical in

4-Bromomethyl-2-Cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystalline powder Storage:Room temperature Package:25kg/drum Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in china

4-Bromomethyl-2-cyanobiphenyl Sartan intermediates

Cas:114772-54-2

Min.Order:25 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

[1,1'-Biphenyl]-2-carbonitrile,4'-(bromomethyl)- 114772-54-2

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

Hangzhou Maytime Bio-Tech Co.,Ltd.

Product :4-Bromomethyl-2-cyanobiphenyl CAS No. 114772-54-2 !--?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /--> Storage:store in sealed container Package:25kgs/fiber drum Application:As sartan intermediate Port:sh

4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $40.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

4-Bromomethyl-2-cyanobiphenyl CAS:114772-54-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

4-Bromomethyl-2-cyanobiphenyl CAS:114772-54-2

Cas:114772-54-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

[1,1'-Biphenyl]-2-carbonitrile,4'-(bromomethyl)-

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

4-Bromomethyl-2-cyanobiphenyl CAS: 114772-54-2 Specification product name 4-bromomethyl-2-cyanobiphenyl cas no. 114772-54-2 appearance white powder assay ≥99% capacity 200mt/yea

Factory supply 4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

[1,1'-Biphenyl]-2-carbonitrile,4'-(bromomethyl)-

Cas:114772-54-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-Bromomethyl-2'-cyanobiphene CAS114772-54-2

Cas:114772-54-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c

4'-bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

4-Bromomethyl-2-cyanobiphenyl

Cas:114772-54-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

inquiry

Synthetic route

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane96%
With bromine In water; 1,2-dichloro-ethane at 84℃; for 0.25h; Temperature; Solvent; Irradiation; Flow reactor;96.3%
With bromine In 1,2-dichloro-ethane at 70℃; for 0.5h; Reagent/catalyst; Temperature; Time; Irradiation;94%
2-cyano-4-methylbiphenyl
64113-85-5

2-cyano-4-methylbiphenyl

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With 5,5-dibromohydantoin In dichloromethane at 50℃; for 0.5h; Temperature; Reagent/catalyst; Irradiation;94%
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane at 100℃; for 2h;
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

2,2'-azobis-(4-methoxy-2,4-dimethylvaleronitrile)

2,2'-azobis-(4-methoxy-2,4-dimethylvaleronitrile)

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With bromine In water89.4%
With N-Bromosuccinimide In water79.6%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

A

2-(4,4-dibromomethylphenyl)benzonitrile
209911-63-7

2-(4,4-dibromomethylphenyl)benzonitrile

B

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide; Azo-bis(2,4-dimethyl-valeronitril) In dichloromethane at 45 - 50℃; for 2 - 5h; Industry scale;A n/a
B 82%
With sodium bromate; hydrogen bromide In dichloromethane; water at 0 - 20℃; UV-irradiation;A 10%
B 80%
With sodium bromate; azobis(2-cyanobutane); bromine In water; chlorobenzene at 70 - 80℃; for 6h;A n/a
B 69%
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

2,2'-azobis (2,4-dimethyl valeronitrile)
4419-11-8, 108346-39-0, 108346-40-3

2,2'-azobis (2,4-dimethyl valeronitrile)

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide In dichloromethane; water80.5%
2,2'-azobis(2-methylbutyronitrile)

2,2'-azobis(2-methylbutyronitrile)

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

chlorobenzene
108-90-7

chlorobenzene

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With bromine75%
2-cyanobenzoic acid
3839-22-3

2-cyanobenzoic acid

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 71 percent / copper(II) oxide; potassium carbonate; potassium fluoride / palladium(II) bromide; 1,10-phenanthroline / quinoline / 24 h / 170 °C
2: 45 percent / N-bromosuccinimide; azobis(isobutyronitrile) / CCl4; cyclohexane / 18 h / 75 °C
View Scheme
ammonium 2-(aminocarbonyl)benzoate
131-63-5

ammonium 2-(aminocarbonyl)benzoate

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 72 percent / acetic anhydride; pyridine
2: 71 percent / copper(II) oxide; potassium carbonate; potassium fluoride / palladium(II) bromide; 1,10-phenanthroline / quinoline / 24 h / 170 °C
3: 45 percent / N-bromosuccinimide; azobis(isobutyronitrile) / CCl4; cyclohexane / 18 h / 75 °C
View Scheme
2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
57598-33-1

2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetrahydrofuran / 2 h / 20 °C
2: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
3: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: magnesium / tetrahydrofuran
2: hydrogenchloride
3: thionyl chloride / water; toluene
4: dibenzoyl peroxide
View Scheme
N-(2-hydroxy-1,1-dimethyl)-2-methoxybenzamide
74201-13-1

N-(2-hydroxy-1,1-dimethyl)-2-methoxybenzamide

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: thionyl chloride / 1 h / 25 °C
2: tetrahydrofuran / 2 h / 20 °C
3: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
4: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole
84392-32-5

4,4-dimethyl-2-(4'-methyl-biphenyl-2-yl)-4,5-dihydrooxazole

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
2: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride
2: thionyl chloride / water; toluene
3: dibenzoyl peroxide
View Scheme
2-Methoxybenzoic acid
579-75-9

2-Methoxybenzoic acid

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 95 percent / thionyl chloride / 18 h / 20 °C
2: CH2Cl2 / 2 h / 20 °C
3: thionyl chloride / 1 h / 25 °C
4: tetrahydrofuran / 2 h / 20 °C
5: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
6: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
2-Methoxybenzoyl chloride
21615-34-9

2-Methoxybenzoyl chloride

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: CH2Cl2 / 2 h / 20 °C
2: thionyl chloride / 1 h / 25 °C
3: tetrahydrofuran / 2 h / 20 °C
4: 96 percent / pyridine, phosphorus oxychloride / 3 h / 100 °C
5: N-bromosuccinimide, dibenzoyl peroxide / CCl4 / 3 h / Heating
View Scheme
chlorobenzene
108-90-7

chlorobenzene

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
In water
sodium bromate

sodium bromate

2,2'-azobis(2-methylbutyronitrile)

2,2'-azobis(2-methylbutyronitrile)

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
In water; chlorobenzene
In water; chlorobenzene
2,2'-azobis(2,4-dimethylvaleronitrile)

2,2'-azobis(2,4-dimethylvaleronitrile)

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

tetrachloromethane
56-23-5

tetrachloromethane

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

dibenzoyl peroxide
94-36-0

dibenzoyl peroxide

A

4'-bromornethyl-2-cyanobiphenyl

4'-bromornethyl-2-cyanobiphenyl

B

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

azobisisobutyronitrile
34241-39-9

azobisisobutyronitrile

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide In water; chlorobenzene
With N-Bromosuccinimide In water; chlorobenzene
With N-Bromosuccinimide In tetrachloromethane
With N-Bromosuccinimide In tetrachloromethane
With N-Bromosuccinimide In tetrachloromethane
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

dibenzoyl peroxide
94-36-0

dibenzoyl peroxide

A

Losartan ›DUP[753]

Losartan ›DUP[753]

B

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide In tetrachloromethane
2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

dibenzoyl peroxide
94-36-0

dibenzoyl peroxide

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With N-Bromosuccinimide In tetrachloromethane
With N-Bromosuccinimide In tetrachloromethane
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 80 °C / Inert atmosphere
2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 40 h / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / N,N-dimethyl-formamide / Inert atmosphere
2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane
View Scheme
Multi-step reaction with 2 steps
1.1: palladium dichloride / methanol; toluene / 0.17 h / 20 °C / Inert atmosphere
1.2: 12 h / 110 °C / Inert atmosphere
2.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / chlorobenzene / 6 h / 70 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / toluene / 6 h / 110 °C / Inert atmosphere
2: sodium bromate; sodium metabisulfite / ethyl acetate; water / 5 h / 0 - 25 °C
View Scheme
4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 80 °C / Inert atmosphere
2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 40 h / 80 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: palladium dichloride / methanol; toluene / 0.17 h / 20 °C / Inert atmosphere
1.2: 12 h / 110 °C / Inert atmosphere
2.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / chlorobenzene / 6 h / 70 °C / Inert atmosphere
View Scheme
benzaldehyde N,N-dimethylhydrazone
1075-70-3

benzaldehyde N,N-dimethylhydrazone

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 4-(dimethylamino)picolinaldehyde N,N-dibenzylhydrazone; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tetrahydrofuran / 24 h / 80 °C / Inert atmosphere
2: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium phosphate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
3: magnesium bis(monoperoxyphthalate)hexahydrate / methanol / 0 h / 20 °C
4: sodium metabisulfite; sodium bromate / water; ethyl acetate / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: 4-(dimethylamino)picolinaldehyde N,N-dibenzylhydrazone; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tetrahydrofuran / 24 h / 80 °C / Inert atmosphere
2: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium phosphate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
3: magnesium bis(monoperoxyphthalate)hexahydrate / methanol / 0 h / 20 °C
4: sodium metabisulfite; sodium bromate / water; ethyl acetate / 20 °C
View Scheme
2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde N,N-dimethylhydrazone
1360607-13-1

2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde N,N-dimethylhydrazone

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium phosphate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere
2: magnesium bis(monoperoxyphthalate)hexahydrate / methanol / 0 h / 20 °C
3: sodium metabisulfite; sodium bromate / water; ethyl acetate / 20 °C
View Scheme
4′-methyl-[1,1′-biphenyl]-2-carbaldehyde N,N-dimethylhydrazone
1404116-53-5

4′-methyl-[1,1′-biphenyl]-2-carbaldehyde N,N-dimethylhydrazone

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: magnesium bis(monoperoxyphthalate)hexahydrate / methanol / 0 h / 20 °C
2: sodium metabisulfite; sodium bromate / water; ethyl acetate / 20 °C
View Scheme
tributyl(p-tolyl)stannane
31614-66-1

tributyl(p-tolyl)stannane

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / N,N-dimethyl-formamide / Inert atmosphere
2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane
View Scheme
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: manganese(ll) chloride; chloro-trimethyl-silane / tetrahydrofuran / -5 - 0 °C / Inert atmosphere; Green chemistry
1.2: 9 h / -5 - 25 °C / Inert atmosphere; Green chemistry
2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 3 h / 80 °C / Green chemistry
View Scheme
4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: manganese(ll) chloride; chloro-trimethyl-silane / tetrahydrofuran / -5 - 0 °C / Inert atmosphere; Green chemistry
1.2: 9 h / -5 - 25 °C / Inert atmosphere; Green chemistry
2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 3 h / 80 °C / Green chemistry
View Scheme
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

Methyl 3-nitro-4-valerylaminobenzoate
127007-35-6

Methyl 3-nitro-4-valerylaminobenzoate

4-[(2'-Cyano-biphenyl-4-ylmethyl)-pentanoyl-amino]-3-nitro-benzoic acid methyl ester
136285-45-5

4-[(2'-Cyano-biphenyl-4-ylmethyl)-pentanoyl-amino]-3-nitro-benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 15h; Ambient temperature;100%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

ethyl butyroyl acetate
3249-68-1

ethyl butyroyl acetate

ethyl 2-<(2'-cyanobiphenyl-4-yl)methyl>-3-oxohexanoate
137860-26-5

ethyl 2-<(2'-cyanobiphenyl-4-yl)methyl>-3-oxohexanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating;98%
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating;
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating; Yield given;
L-valine benzyl ester p-toluenesulfonate salt
16652-76-9

L-valine benzyl ester p-toluenesulfonate salt

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

(S)-2-[(2'-cyanobiphenyl-4-ylmethyl)amino]-3-methylbutyric acid benzyl ester hydrochloride
137864-24-5

(S)-2-[(2'-cyanobiphenyl-4-ylmethyl)amino]-3-methylbutyric acid benzyl ester hydrochloride

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester p-toluenesulfonate salt With sodium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene; water at 20℃; pH=< 8.5 - 9; Large scale;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In 5,5-dimethyl-1,3-cyclohexadiene at 60℃; for 3.41667h; Large scale;
Stage #3: With hydrogenchloride In 5,5-dimethyl-1,3-cyclohexadiene; water at 72℃; for 2h; Dean-Stark; Large scale;
98%
Stage #1: L-valine benzyl ester p-toluenesulfonate salt; 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile With tetrabutylammomium bromide; potassium carbonate; potassium iodide In water; toluene at 50 - 55℃; for 25h;
Stage #2: With hydrogenchloride In water; toluene pH=1 - 2; Product distribution / selectivity;
90%
Stage #1: L-valine benzyl ester p-toluenesulfonate salt; 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile With tetrabutylammomium bromide; potassium carbonate; potassium iodide In water; toluene
Stage #2: With hydrogenchloride In water; toluene pH=1 - 2; Product distribution / selectivity;
90%
N-phenylpentanamide
10264-18-3

N-phenylpentanamide

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

N-((2′-cyano[1,1′-biphenyl]-4-yl)methyl)-N-phenylpentanamide

N-((2′-cyano[1,1′-biphenyl]-4-yl)methyl)-N-phenylpentanamide

Conditions
ConditionsYield
Stage #1: N-phenylpentanamide With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;
98%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

N-(2'-cyanobiphenyl-4-ylmethyl)-N-propyl-amine
143096-18-8

N-(2'-cyanobiphenyl-4-ylmethyl)-N-propyl-amine

Conditions
ConditionsYield
96%
methyl 4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylate hydrochloride
1206680-19-4

methyl 4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylate hydrochloride

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-cyano-4'-[2"-n-propyl-4"-methyl-6"-methylcarboxylate-benzimidazole-1"-ylmethyl]biphenyl
1098100-86-7

2-cyano-4'-[2"-n-propyl-4"-methyl-6"-methylcarboxylate-benzimidazole-1"-ylmethyl]biphenyl

Conditions
ConditionsYield
Stage #1: methyl 4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylate hydrochloride With sodium carbonate; sodium iodide In acetone
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In acetone for 15h; Product distribution / selectivity; Reflux;
95%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

4'-(benzothiazol-2-ylsulfanylmethyl)-biphenyl-2-carbonitrile
721970-96-3

4'-(benzothiazol-2-ylsulfanylmethyl)-biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In acetonitrile at 20℃; for 1.33333h;94.7%
2-(4-fluoro-benzylsulfanyl)-3H-quinazolin-4-thione
1429045-74-8

2-(4-fluoro-benzylsulfanyl)-3H-quinazolin-4-thione

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

C29H20FN3S2
1429045-99-7

C29H20FN3S2

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;94%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

methyl 4-hydroxylbenzoate
99-76-3

methyl 4-hydroxylbenzoate

methyl 4-[(2'-cyanobiphenyl-4-yl)methoxy]benzoate

methyl 4-[(2'-cyanobiphenyl-4-yl)methoxy]benzoate

Conditions
ConditionsYield
With potassium carbonate In butanone at 78 - 80℃; for 2h;93.5%
2-butyl-4-(4-fluorophenyl)-1H-imidazole-5-carbaldehyde
1313233-70-3

2-butyl-4-(4-fluorophenyl)-1H-imidazole-5-carbaldehyde

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4'-[{2-butyl-4-(4-fluorophenyl)-5-formyl-1H-imidazol-1-yl}methyl]biphenyl-2-carbonitrile
1313233-71-4

4'-[{2-butyl-4-(4-fluorophenyl)-5-formyl-1H-imidazol-1-yl}methyl]biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 4h;93.2%
Ethyl 3-oxoheptanoate
7737-62-4

Ethyl 3-oxoheptanoate

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-(2'-Cyano-biphenyl-4-ylmethyl)-3-oxo-heptanoic acid ethyl ester
137860-02-7

2-(2'-Cyano-biphenyl-4-ylmethyl)-3-oxo-heptanoic acid ethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating;93%
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating;
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating; Yield given;
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

(6-Butyl-2-oxo-1,2-dihydro-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester
147876-57-1

(6-Butyl-2-oxo-1,2-dihydro-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester

6-butyl-1-(2'-cyanobiphenyl-4-ylmethyl)-1,2-dihydro-2-oxo-3-tert-butoxycarbonylaminomethyl pyridine
147876-52-6

6-butyl-1-(2'-cyanobiphenyl-4-ylmethyl)-1,2-dihydro-2-oxo-3-tert-butoxycarbonylaminomethyl pyridine

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane for 72h; Heating;92%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

dimethyl amine
124-40-3

dimethyl amine

4'-((dimethylamino)methyl)-[1,1'-biphenyl]-2-carbonitrile
1000930-96-0

4'-((dimethylamino)methyl)-[1,1'-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
In diethyl ether; water at 20℃;92%
8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,,6-dihydro-1H-purine-2,6-dione
666816-98-4

8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,,6-dihydro-1H-purine-2,6-dione

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4'-((8-bromo-7-(but-2-ynyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)biphenyl-2-carbonitrile

4'-((8-bromo-7-(but-2-ynyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 55℃; for 6h;92%
benzoimidazole
51-17-2

benzoimidazole

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4′-((1H-benzo[d]imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-carbonitrile
136285-25-1

4′-((1H-benzo[d]imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
Stage #1: benzoimidazole With potassium hydroxide In dimethyl sulfoxide at 100℃; for 2h;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In dimethyl sulfoxide for 12h;
92%
5-methyl-3-oxo-hexanoic acid ethyl ester
34036-16-3

5-methyl-3-oxo-hexanoic acid ethyl ester

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-(2'-Cyano-biphenyl-4-ylmethyl)-5-methyl-3-oxo-hexanoic acid ethyl ester
137860-48-1

2-(2'-Cyano-biphenyl-4-ylmethyl)-5-methyl-3-oxo-hexanoic acid ethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; lithium chloride In tetrahydrofuran for 15h; Heating;91%
2-propyl-1H-benzimidazole
5465-29-2

2-propyl-1H-benzimidazole

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile
136285-23-9

4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
Stage #1: 2-propyl-1H-benzimidazole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In N,N-dimethyl-formamide at 0 - 20℃;
91%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 3h; Cooling with ice;70%
Stage #1: 2-propyl-1H-benzimidazole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
quinazoline-4(3H)-thione
3337-86-8

quinazoline-4(3H)-thione

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

C22H15N3S
1429045-94-2

C22H15N3S

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;91%
1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole

1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

hydrobromide 4'-(3,4-dihydropyrimido[1,2-a]benzimidazole-10(2H)-ylmethyl) biphenyl-2-carbonitrile

hydrobromide 4'-(3,4-dihydropyrimido[1,2-a]benzimidazole-10(2H)-ylmethyl) biphenyl-2-carbonitrile

Conditions
ConditionsYield
In nitromethane for 7.5h; Heating;91%
7-amino-4-(azidomethyl)-2H-chromen-2-one
1186293-68-4

7-amino-4-(azidomethyl)-2H-chromen-2-one

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

C24H17N5O2

C24H17N5O2

Conditions
ConditionsYield
With sodium carbonate In acetone for 6h; Reflux;90.5%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride

2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride

4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
138401-24-8

4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 0.0208333h; microwave irradiation;90%
Stage #1: 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride With potassium carbonate; tetrabutylammomium bromide In water at 25 - 30℃; for 2h; Inert atmosphere;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In water at 55 - 60℃; Product distribution / selectivity;
84.2%
With tetrabutylammomium bromide; sodium hydroxide In Isopropyl acetate at 0 - 30℃; for 12h; Solvent;39%
4-amino-phenol
123-30-8

4-amino-phenol

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4'-((4-hydroxyphenylamino)methyl)biphenyl-2-carbonitrile

4'-((4-hydroxyphenylamino)methyl)biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide Reflux;90%
4-trifluoromethylphenylamine
455-14-1

4-trifluoromethylphenylamine

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

4'-((4-(trifluoromethyl)phenylamino)methyl)biphenyl-2-carbonitrile

4'-((4-(trifluoromethyl)phenylamino)methyl)biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide Reflux;90%
5-chloro-1,7’-dimethyl-2’-propyl-1H,3’H-2,5’-bibenzo[d]imidazole

5-chloro-1,7’-dimethyl-2’-propyl-1H,3’H-2,5’-bibenzo[d]imidazole

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

C33H28ClN5

C33H28ClN5

Conditions
ConditionsYield
Stage #1: 5-chloro-1,7’-dimethyl-2’-propyl-1H,3’H-2,5’-bibenzo[d]imidazole With sodium hydroxide In water; acetone for 0.5h;
Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In water; acetone at 25℃;
90%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

(Z)-4'-(bromomethyl)-N'-hydroxy-[1,1'-biphenyl]-2-carboxamidine

(Z)-4'-(bromomethyl)-N'-hydroxy-[1,1'-biphenyl]-2-carboxamidine

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium methylate In tetrahydrofuran; methanol at 20 - 30℃; Solvent; Reagent/catalyst; Temperature;89.9%
With hydroxylamine hydrochloride; sodium carbonate In dimethyl sulfoxide at 25 - 80℃; Reagent/catalyst; Solvent; Temperature;85.4%
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
114772-54-2

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

2-nitro-aniline
88-74-4

2-nitro-aniline

4'-((2-nitrophenylamino)methyl)biphenyl-2-carbonitrile

4'-((2-nitrophenylamino)methyl)biphenyl-2-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide Reflux;89%
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View