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Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

factory supply Fenofibrate API Raw Material Fenofibrate Powder CAS 49562-28-9

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $5.6 / 5.8

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Fenofibrate Manufacturer/High quality/Best price/In stock

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

factory supply 99% API Raw Material Fenofibrate Powder

Cas:49562-28-9

Min.Order:1 Metric Ton

FOB Price: $25.0 / 500.0

Type:Trading Company

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Kono Chem Co.,Ltd

Superiority KONO is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in

High quality fenofibrate 49562-28-9 with best price

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Fenofibrate Cas 49562-28-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:25kg/drum

High quality Fenofibrate Cas 49562-28-9 with cheap price and fast delivery

Cas:49562-28-9

Min.Order:25 Kilogram

FOB Price: $30.0 / 36.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Fast Shipping API Hypolipidemic Raw Materials Fenofibrate Powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives

Fast Shipping API Hypolipidemic Raw Materials Fenofibrate Powder

Cas:49562-28-9

Min.Order:500 Kilogram

FOB Price: $54.0 / 56.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

APIs Appearance:Crystalline Solid Storage:Store at RT Package:25kg/drum or acc to customers' request Application:antihyperlipidemic Transportation:acc to customers' request Port:Shanghai Port

Fenofibrate

Cas:49562-28-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Fenofibrate manufacturer with low price

Cas:49562-28-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Fenofibrate

Cas:49562-28-9

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Fenofibrate 49562-28-9 ISO Producer

Cas:49562-28-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Fenofibrate

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Fenofibrate

Cas:49562-28-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Fenofibrate

Cas:49562-28-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

1 Factory price 2 High quality 3 Good service Appearance:Powder Storage:Dry and cold condition Package:25KG, 500KG and1000KG, seaworthy and suitable for container transportation. Application:coatings, printing ink, rubber, glass, leather, cos

49562-28-9 Chemicals Pharmaceutical Raw Materials CAS49562-28-9/ Fenofibrate

Cas:49562-28-9

Min.Order:20 Metric Ton

FOB Price: $2100.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Fenofibrate Powder CAS 49562-28-9

Cas:49562-28-9

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 49562-28-9 with best quality

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Fenofibrate 49562-28-9

Cas:49562-28-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Fenofibrate/ LIDE PHARMA- Factory supply / Best price

Cas:49562-28-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product name Fenofibrate CAS NO. 49562-28-9 Synonyms Fenofibrate Category Pharmaceutical Raw Materials,Active Pharmaceutical Ing

Fenofibrate

Cas:49562-28-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystalline powder Storage:Room temperature Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in china

High Quality Manufacturer Fenofibrate API

Cas:49562-28-9

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

CAS 49562-28-9 Fenofibrate Elasterin Powder for Antilipemic

Cas:49562-28-9

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

Hangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in y

fenofibrate

Cas:49562-28-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Fenofibrate Molecular Structure: Formula: C20H21ClO4 Molecular Weight : 360.83 Synonyms: 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci1-methylethyle

Factory Supply Fenofibrate

Cas:49562-28-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White powder Storage:storage in a dr

99%Fenofibrate with high quality

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Antilipemic drugs Fenofibrate/CAS:49562-28-9

Cas:49562-28-9

Min.Order:1 Kilogram

FOB Price: $82.0 / 94.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Fenofibrate CAS: 49562-28-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

Fenofibrate CAS: 49562-28-9

Cas:49562-28-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

CAS 49562-28-9 Fenofibrate

Cas:49562-28-9

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Fenofibrate

Cas:49562-28-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:49562-28-9

Cas:49562-28-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

fenofibric acid
42017-89-0

fenofibric acid

isopropyl alcohol
67-63-0

isopropyl alcohol

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With magneticnanosolidsuperacid In cyclohexane; water at 83 - 85℃; Reagent/catalyst; Temperature;97%
Stage #1: fenofibric acid; isopropyl alcohol With thionyl chloride for 7h; Reflux;
Stage #2: With potassium carbonate In water at 60 - 65℃;
96.6%
With macroporous strong acid cation exchange resin D001 In water; toluene at 110℃;92.4%
fenofibric acid
42017-89-0

fenofibric acid

isopropyl bromide
75-26-3

isopropyl bromide

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Stage #1: fenofibric acid With potassium carbonate In Isopropyl acetate; dimethyl sulfoxide at 20 - 90℃; for 0.75h; Industry scale; Inert atmosphere;
Stage #2: isopropyl bromide In Isopropyl acetate; dimethyl sulfoxide at 80 - 95℃; for 5.83333h;
94.9%
isopropyl 2-(4-(1-(4-chlorophenyl)-2-methoxyvinyl)phenoxy)-2-methylpropanoate

isopropyl 2-(4-(1-(4-chlorophenyl)-2-methoxyvinyl)phenoxy)-2-methylpropanoate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; copper (II) carbonate hydroxide; TPGS-750-M In water at 20℃; Green chemistry;91%
isopropyl 2-bromo-2‑methylpropanoate
51368-55-9

isopropyl 2-bromo-2‑methylpropanoate

4-chloro-4'-hydroxybenzophenone
42019-78-3

4-chloro-4'-hydroxybenzophenone

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With potassium hydrogencarbonate In isopropyl alcohol for 48h; Reflux;90%
Stage #1: 4-chloro-4'-hydroxybenzophenone With sodium hydroxide In butanone for 1h; Reflux;
Stage #2: isopropyl 2-bromo-2‑methylpropanoate In butanone for 8h; Reflux;
90%
Stage #1: 4-chloro-4'-hydroxybenzophenone With potassium hydrogencarbonate In isopropyl alcohol at 25℃; for 0.166667h;
Stage #2: isopropyl 2-bromo-2‑methylpropanoate In isopropyl alcohol at 90℃; for 48h;
90%
isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

molybdenum hexacarbonyl
13939-06-5, 199620-15-0

molybdenum hexacarbonyl

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With potassium phosphate; palladium(II) trifluoroacetate In water; acetonitrile at 50℃; for 6h; Suzuki Coupling; Inert atmosphere; Sealed tube;90%
carbon monoxide
201230-82-2

carbon monoxide

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With potassium carbonate; palladium dichloride at 80℃; for 16h; Sealed tube;89%
With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; triethylamine In 1,4-dioxane at 80℃; for 20h; Inert atmosphere; Sealed tube; Cooling with ice;80%
With potassium carbonate; triphenylphosphine; palladium dichloride at 80℃; for 18h;65 %Chromat.
isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

9-methyl-9H-fluorene-9-carbonyl chloride
82102-37-2

9-methyl-9H-fluorene-9-carbonyl chloride

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Stage #1: 9-methyl-9H-fluorene-9-carbonyl chloride With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); tri tert-butylphosphoniumtetrafluoroborate at 80℃;
Stage #2: isopropyl 2-(4-iodophenoxy)-2-methylpropanoate; 4-Chlorophenylboronic acid With potassium carbonate; palladium dichloride at 80℃;
84%
isopropyl 2-(4-bromophenoxy)-2-methylpropanoate
1581307-35-8

isopropyl 2-(4-bromophenoxy)-2-methylpropanoate

2-(4-chloro-phenyl)-[1,3,6,2]dioxazaborocane
5123-08-0

2-(4-chloro-phenyl)-[1,3,6,2]dioxazaborocane

9-methyl-9H-fluorene-9-carbonyl chloride
82102-37-2

9-methyl-9H-fluorene-9-carbonyl chloride

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With palladium(II) acetylacetonate; N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); tri tert-butylphosphoniumtetrafluoroborate; di(1-adamantyl)-N-butylphosphine hydroiodide In water; N,N-dimethyl-formamide; toluene at 80℃; for 16h; Suzuki-Miyaura Coupling; Inert atmosphere; Glovebox;83%
1-Chloro-4-iodobenzene
637-87-6

1-Chloro-4-iodobenzene

carbon monoxide
201230-82-2

carbon monoxide

C13H18O3

C13H18O3

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With 2,6-di-tert-butyl-pyridine; bis(η3-allyl-μ-chloropalladium(II)); silver(I) triflimide In 1,2-dichloro-ethane at 65℃; under 22801.5 Torr; for 24h; Reagent/catalyst; Inert atmosphere; Sealed tube; Glovebox; Schlenk technique;83%
4-((4-chlorophenyl)(hydroxy)methyl)phenol
61001-99-8

4-((4-chlorophenyl)(hydroxy)methyl)phenol

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With oxygen; Langlois reagent In acetonitrile at 25℃; under 760.051 Torr; for 12h; Irradiation;83%
carbon monoxide
201230-82-2

carbon monoxide

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

potassium (4-chlorophenyl)trifluoroborate

potassium (4-chlorophenyl)trifluoroborate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With sodium carbonate; Trimethylacetic acid at 120℃; under 760.051 Torr; for 12h; Suzuki Coupling;80%
C14H20O3

C14H20O3

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With palladium diacetate; N-picolinoylcyclohexylamine; potassium hydrogencarbonate In tert-Amyl alcohol at 150℃; for 24h;75%
isopropyl 2-(4-(1-(4-chlorophenyl)vinyl)phenoxy)-2-methylpropaoate

isopropyl 2-(4-(1-(4-chlorophenyl)vinyl)phenoxy)-2-methylpropaoate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With 1-hydroxy-pyrrolidine-2,5-dione; graphitic carbon nitride; oxygen In acetonitrile at 20℃; Inert atmosphere; Irradiation;75%
With 1,1'-bis-(diphenylphosphino)ferrocene; oxygen; 2,5-Dimercapto-1,3,4-thiadiazole In acetonitrile at 20 - 80℃; under 760.051 Torr; for 15h; Schlenk technique;67%
1-Chloro-4-iodobenzene
637-87-6

1-Chloro-4-iodobenzene

2-(4-((1-isopropoxy-2-methyl-1-oxopropan-2-yl)oxy)phenyl)-2-oxoacetic acid

2-(4-((1-isopropoxy-2-methyl-1-oxopropan-2-yl)oxy)phenyl)-2-oxoacetic acid

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With (1,2-dimethoxyethane)dichloronickel(II); [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; lithium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine In water; N,N-dimethyl-formamide for 96h; Inert atmosphere; Irradiation;71%
With [nickel(II)dichloride(dimethoxyethane)]; Ir[dF(CF3)ppy]2(dtbbpy)PF6; lithium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine In water; N,N-dimethyl-formamide for 96h; Inert atmosphere; Sealed tube; Microwave irradiation;71%
3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide
50978-45-5

3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With potassium phosphate; sodium carbonate; N-ethyl-N,N-diisopropylamine at 120℃; for 48h;69%
C13H17O3(1-)*C5H9O2(1-)*Zn(2+)

C13H17O3(1-)*C5H9O2(1-)*Zn(2+)

S-(2-pyridinyl) 4-chlorobenzenecarbothioate
74032-43-2

S-(2-pyridinyl) 4-chlorobenzenecarbothioate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With 4,4'-di-tert-butyl-2,2'-bipyridine; cobalt(II) chloride In tetrahydrofuran at 25℃; for 4h;65%
bromochlorobenzene
106-39-8

bromochlorobenzene

ethylene glycol dimethyl ether nickel bromide

ethylene glycol dimethyl ether nickel bromide

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With nickel(II) bromide dimethoxyethane; potassium phosphate; Ir(dFCF3(ppy))2(4,4’-ditert-butyl-2,2’-bipyrididyl)PF6; caesium carbonate; triphenylphosphine; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl-formamide; acetonitrile at 25℃; for 20h; Inert atmosphere;65%
isopropyl 2-(4-iodophenoxy)-2-methylpropanoate
1375008-18-6

isopropyl 2-(4-iodophenoxy)-2-methylpropanoate

para-Chlorobenzyl alcohol
873-76-7

para-Chlorobenzyl alcohol

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; palladium diacetate; silver(l) oxide In water at 120℃; for 24h; Schlenk technique; Inert atmosphere;52%
(p-chlorophenyl)triethoxysilane
21700-74-3

(p-chlorophenyl)triethoxysilane

isopropyl 2-(4-(2,6-dioxopiperidine-1-carbonyl)phenoxy)-2-methylpropanoate

isopropyl 2-(4-(2,6-dioxopiperidine-1-carbonyl)phenoxy)-2-methylpropanoate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With lithium acetate; palladium diacetate; triethylamine tris(hydrogen fluoride); tricyclohexylphosphine In 1,4-dioxane; water at 90℃; for 6h; Hiyama Coupling;45%
chloroform
67-66-3

chloroform

4-chloro-4'-hydroxybenzophenone
42019-78-3

4-chloro-4'-hydroxybenzophenone

isopropyl alcohol
67-63-0

isopropyl alcohol

acetone
67-64-1

acetone

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
(i) KOH, (ii) /BRN= 1731042/, (iii) /BRN= 635639/, H2SO4, benzene; Multistep reaction;
4-chloro-4'-hydroxybenzophenone
42019-78-3

4-chloro-4'-hydroxybenzophenone

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With potassium carbonate In water
Multi-step reaction with 2 steps
1: sodium hydroxide
2: sulfuric acid
View Scheme
2-(4-chlorophenyl)-1,3-dithiane
10359-09-8

2-(4-chlorophenyl)-1,3-dithiane

isopropyl 2-(4-bromophenoxy)-2-methylpropanoate
1581307-35-8

isopropyl 2-(4-bromophenoxy)-2-methylpropanoate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bis(η3-allyl-μ-chloropalladium(II)); lithium hexamethyldisilazane; nixantphos / 3 h / 20 °C / Schlenk technique; Sealed tube; Inert atmosphere
2: N-Bromosuccinimide; water / 1.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: nixantphos; bis(η3-allyl-μ-chloropalladium(II)); lithium hexamethyldisilazane / tetrahydrofuran / 3 h / 24 °C / Sealed tube; Inert atmosphere; Schlenk technique
2: N-Bromosuccinimide; water / tetrahydrofuran / 1.5 h / 24 °C
View Scheme
C23H27ClO3S2

C23H27ClO3S2

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
With N-Bromosuccinimide; water at 20℃; for 1.5h;3.1 g
With N-Bromosuccinimide; water In tetrahydrofuran at 24℃; for 1.5h;3.1 g
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 12 h / 90 °C
2: selenium(IV) oxide; pyridine / 14 h / 110 °C
3: (1,2-dimethoxyethane)dichloronickel(II); [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; lithium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine / N,N-dimethyl-formamide; water / 96 h / Inert atmosphere; Irradiation
View Scheme
isopropyl 2-bromo-2‑methylpropanoate
51368-55-9

isopropyl 2-bromo-2‑methylpropanoate

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 12 h / 90 °C
2: selenium(IV) oxide; pyridine / 14 h / 110 °C
3: (1,2-dimethoxyethane)dichloronickel(II); [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; lithium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine / N,N-dimethyl-formamide; water / 96 h / Inert atmosphere; Irradiation
View Scheme
C19H23ClO2Si

C19H23ClO2Si

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere; Schlenk technique
2: potassium carbonate / acetonitrile / 18 h / Inert atmosphere; Schlenk technique; Reflux
View Scheme
4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: C42H36ClFeN2O4PPdS*C6H15N; sodium carbonate / water; toluene / 1 h / 50 °C / Inert atmosphere; Schlenk technique
2: sodium hydroxide / water; dimethyl sulfoxide / 16 h / 120 °C / Inert atmosphere; Schlenk technique
3: potassium carbonate / acetonitrile / 18 h / Inert atmosphere; Schlenk technique; Reflux
View Scheme
4-fluorobenzoyl chloride
403-43-0

4-fluorobenzoyl chloride

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: C42H36ClFeN2O4PPdS*C6H15N; sodium carbonate / water; toluene / 1 h / 50 °C / Inert atmosphere; Schlenk technique
2: sodium hydroxide / water; dimethyl sulfoxide / 16 h / 120 °C / Inert atmosphere; Schlenk technique
3: potassium carbonate / acetonitrile / 18 h / Inert atmosphere; Schlenk technique; Reflux
View Scheme
4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

fenofibrate
49562-28-9

fenofibrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: C42H36ClFeN2O4PPdS*C6H15N; sodium carbonate / water; toluene / 1 h / 50 °C / Inert atmosphere; Schlenk technique
2: sodium hydroxide / water; dimethyl sulfoxide / 16 h / 120 °C / Inert atmosphere; Schlenk technique
3: potassium carbonate / acetonitrile / 18 h / Inert atmosphere; Schlenk technique; Reflux
View Scheme
fenofibrate
49562-28-9

fenofibrate

cholin hydroxide
123-41-1

cholin hydroxide

choline fenofibrate
856676-23-8

choline fenofibrate

Conditions
ConditionsYield
In ethanol at 80℃; for 5h; Solvent; Large scale;100%
fenofibrate
49562-28-9

fenofibrate

fenofibric acid
42017-89-0

fenofibric acid

Conditions
ConditionsYield
With water; triethylamine; lithium bromide In acetonitrile for 7h; Heating;99%
With iodine; aluminium In acetonitrile at 80℃; for 18h;97%
With sodium hydroxide In methanol at 69.85℃; for 4h;85%
Dibenzothiophene sulfoxide
1013-23-6

Dibenzothiophene sulfoxide

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

fenofibrate
49562-28-9

fenofibrate

C32H28ClO4S(1+)*CF3O3S(1-)

C32H28ClO4S(1+)*CF3O3S(1-)

Conditions
ConditionsYield
In dichloromethane at -40 - 25℃; for 0.5h; Schlenk technique; Inert atmosphere; Glovebox;98%
fenofibrate
49562-28-9

fenofibrate

C20H17(2)H4ClO4

C20H17(2)H4ClO4

Conditions
ConditionsYield
With silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; 2-methyl-3-trifluoromethylaniline; water-d2; para-chlorobenzoic acid In 1,2-dichloro-ethane at 120℃; for 16h; Schlenk technique; Inert atmosphere;98%
fenofibrate
49562-28-9

fenofibrate

4-((4-chlorophenyl)(hydroxy)methyl)phenol
61001-99-8

4-((4-chlorophenyl)(hydroxy)methyl)phenol

Conditions
ConditionsYield
With C28H35ClCoN5(1+)*Cl(1-); potassium tert-butylate; hydrogen In tetrahydrofuran at 20℃; under 37503.8 Torr; for 16h; Pressure; Temperature; Autoclave;97%
With potassium borohydride
fenofibrate
49562-28-9

fenofibrate

isopropyl 2-(4-(4-deuteriobenzoyl)phenoxy)-2-methylpropanoate
1610958-42-3

isopropyl 2-(4-(4-deuteriobenzoyl)phenoxy)-2-methylpropanoate

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); 1-deuteriodiphenylmethanol; 3-(2,6-dibenzhydryl-4-methylphenyl)-4,5-dimethyl-1-(2,4,6-trimethylbenzyl)imidazolium chloride; caesium carbonate In toluene at 90℃; for 16h; Inert atmosphere;95%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; d8-isopropanol; potassium carbonate; bis(dibenzylideneacetone)-palladium(0) In acetonitrile at 100℃; for 2.5h; Inert atmosphere; Microwave irradiation;90%
fenofibrate
49562-28-9

fenofibrate

isopropyl 2-(4-((4-chlorophenyl)(imino)methyl)phenoxy)-2-methylpropanoate

isopropyl 2-(4-((4-chlorophenyl)(imino)methyl)phenoxy)-2-methylpropanoate

Conditions
ConditionsYield
With 1,1,1,3,3,3-hexamethyl-disilazane; scandium tris(trifluoromethanesulfonate) In chlorobenzene at 90℃; for 24h; Inert atmosphere;93%
fenofibrate
49562-28-9

fenofibrate

cyclopropylboronic acid
411235-57-9

cyclopropylboronic acid

C23H26O4

C23H26O4

Conditions
ConditionsYield
With potassium phosphate monohydrate; tris(1-adamantyl)phosphine; C28H26N2O8Pd2S2 In tetrahydrofuran; toluene at 100℃; for 5h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;92%
With potassium phosphate monohydrate; tris(1-adamantyl)phosphine; {2-[((acetyl-κO)amino)phenyl-κC](tri-1-adamantylphosphine)palladium}(p-toluenesulfonate) In tetrahydrofuran; toluene at 100℃; for 5h; Suzuki-Miyaura Coupling; Inert atmosphere;92%
fenofibrate
49562-28-9

fenofibrate

2,4-dimethylbenzeneboronic acid
55499-44-0

2,4-dimethylbenzeneboronic acid

C28H30O4

C28H30O4

Conditions
ConditionsYield
With potassium phosphate monohydrate; palladium diacetate; N2Phos In water; toluene at 45℃; for 16h; Suzuki-Miyaura Coupling;92%
With C35H47O3P*C15H16N(1-)*CH3O3S(1-)*Pd(2+); triethylamine In tetrahydrofuran; water at 45℃; for 24h; Suzuki-Miyaura Coupling;91%
fenofibrate
49562-28-9

fenofibrate

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

isopropyl 2-methyl-2-(4-(4-((3-(trifluoromethyl)phenyl)amino)benzoyl)phenoxy)propanoate

isopropyl 2-methyl-2-(4-(4-((3-(trifluoromethyl)phenyl)amino)benzoyl)phenoxy)propanoate

Conditions
ConditionsYield
With methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II); potassium hydroxide In water; toluene at 110℃; Flow reactor;91%
2-(2-methylphenyl)pyridine
10273-89-9

2-(2-methylphenyl)pyridine

fenofibrate
49562-28-9

fenofibrate

C32H31NO4

C32H31NO4

Conditions
ConditionsYield
With C17H24N5Ru(1+)*F6P(1-); potassium acetate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 35℃; for 24h; Inert atmosphere;90%
With C17H24N5Ru(1+)*F6P(1-); potassium acetate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 35℃; for 24h; Inert atmosphere; Glovebox;90%
fenofibrate
49562-28-9

fenofibrate

1-phenyl-2-bromoethane
103-63-9

1-phenyl-2-bromoethane

isopropyl 2-methyl-2-(4-(4-(1-phenylethyl)benzoyl)phenoxy)propanoate

isopropyl 2-methyl-2-(4-(4-(1-phenylethyl)benzoyl)phenoxy)propanoate

Conditions
ConditionsYield
With 2.9-dimethyl-1,10-phenanthroline; nickel(II) perchlorate hexahydrate; tetrabutylammomium bromide In N,N-dimethyl acetamide at 20℃; for 10h; Glovebox; Sealed tube; Electrochemical reaction; Inert atmosphere; regioselective reaction;90%
fenofibrate
49562-28-9

fenofibrate

4-fluoroaniline
371-40-4

4-fluoroaniline

isopropyl 2-(4-(4-((4-fluorophenyl)amino)benzoyl)phenoxy)-2-methylpropanoate

isopropyl 2-(4-(4-((4-fluorophenyl)amino)benzoyl)phenoxy)-2-methylpropanoate

Conditions
ConditionsYield
With Pd(PAd3)(4-FC6H4)Br; triethylamine In water; toluene at 100℃; for 36h; Solvent; Temperature; Inert atmosphere; Glovebox;90%
2-methyl-4,5-dihydro-1,3-oxazole
1120-64-5

2-methyl-4,5-dihydro-1,3-oxazole

fenofibrate
49562-28-9

fenofibrate

(2-acetoxyethylamino)fenofibrate

(2-acetoxyethylamino)fenofibrate

Conditions
ConditionsYield
Stage #1: 2-methyl-4,5-dihydro-1,3-oxazole; fenofibrate With magnesium(II) perchlorate In acetonitrile at 20℃; Inert atmosphere; Electrochemical reaction;
Stage #2: With sodium hydrogencarbonate In hexane; water; ethyl acetate Inert atmosphere; chemoselective reaction;
88%
fenofibrate
49562-28-9

fenofibrate

Selectfluor
140681-55-6

Selectfluor

C27H34Cl2N2O4(2+)*2BF4(1-)

C27H34Cl2N2O4(2+)*2BF4(1-)

Conditions
ConditionsYield
With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; C20H28N4O2Pd(2+)*2BF4(1-) In acetonitrile at 23℃; for 24h; regioselective reaction;88%
fenofibrate
49562-28-9

fenofibrate

isopropyl 2-(4-(4-hydroxybenzoyl)phenoxy)-2-methylpropanoate
61002-03-7

isopropyl 2-(4-(4-hydroxybenzoyl)phenoxy)-2-methylpropanoate

Conditions
ConditionsYield
With tris(6,6'-diamino-2,2'-bipyridine); 4,4-diphenyl-1,3,5,7,8-pentamethyl-2,6-diethyl-4-bora-3a,4a-diaza-s-indacene; Br2Ni*3H2O; water; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide; acetonitrile at 20℃; for 24h; Glovebox; Irradiation; Inert atmosphere;88%
With acetylhydroxamic acid; potassium carbonate In dimethyl sulfoxide at 80℃; for 40h; Sealed tube;46%
fenofibrate
49562-28-9

fenofibrate

C28H37AgF2N2S

C28H37AgF2N2S

isopropyl 2-(4-(4-((difluoromethyl)thio)benzoyl)phenoxy)-2-methylpropanoate

isopropyl 2-(4-(4-((difluoromethyl)thio)benzoyl)phenoxy)-2-methylpropanoate

Conditions
ConditionsYield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; [(2-di-cyclohexylphosphino-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1‘-biphenyl)-2-(2‘-amino-1,1’-biphenyl)]palladium(II) methanesulfonate In tetrahydrofuran at 80℃; for 2h; Inert atmosphere; Schlenk technique;88%
tetrafluoroboric acid diethyl ether
67969-82-8

tetrafluoroboric acid diethyl ether

thianthrene-5-oxide
2362-50-7

thianthrene-5-oxide

fenofibrate
49562-28-9

fenofibrate

C32H28ClO4S2(1+)*BF4(1-)

C32H28ClO4S2(1+)*BF4(1-)

Conditions
ConditionsYield
With trifluoroacetic anhydride In acetonitrile at 0 - 23℃; under 760.051 Torr; for 2h;88%
fenofibrate
49562-28-9

fenofibrate

acetone
67-64-1

acetone

isopropyl 2-methyl-2-(4-(4-(2-oxopropyl)benzoyl)phenoxy)propanoate

isopropyl 2-methyl-2-(4-(4-(2-oxopropyl)benzoyl)phenoxy)propanoate

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); (R)-1-[(Sp)-2-(dicyclohexylphosphanyl)ferrocenylethyl]diphenylphosphane; cesium fluoride at 120℃; for 18h; Reagent/catalyst; Inert atmosphere;88%
fenofibrate
49562-28-9

fenofibrate

potassium vinyltrifluoroborate

potassium vinyltrifluoroborate

isopropyl 2-methyl-2-(4-(4-vinylbenzoyl)phenoxy)propanoate

isopropyl 2-methyl-2-(4-(4-vinylbenzoyl)phenoxy)propanoate

Conditions
ConditionsYield
With caesium carbonate; palladium dichloride; ruphos In tetrahydrofuran; water at 85℃; for 20h; Sealed tube; Inert atmosphere;86%
Suzuki Coupling; Schlenk technique;
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; potassium carbonate In 1,4-dioxane; water at 90℃; Schlenk technique; Inert atmosphere;
With caesium carbonate; palladium dichloride; ruphos In tetrahydrofuran; water at 85℃; for 20h; Inert atmosphere; Sealed tube;
1-fluoro-2-iodoethane
762-51-6

1-fluoro-2-iodoethane

fenofibrate
49562-28-9

fenofibrate

2-methyl-2-(4-(4-(2-fluoroethyl)benzoyl)phenoxy)propionate isopropyl

2-methyl-2-(4-(4-(2-fluoroethyl)benzoyl)phenoxy)propionate isopropyl

Conditions
ConditionsYield
With manganese; 4,4'-Dimethoxy-2,2'-bipyridin; magnesium chloride; nickel dibromide In 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;86%
With manganese; 4,4'-Dimethoxy-2,2'-bipyridin; magnesium chloride; nickel dibromide In 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Inert atmosphere; Sealed tube;86%
fenofibrate
49562-28-9

fenofibrate

C8H6BF6(1-)*K(1+)

C8H6BF6(1-)*K(1+)

C28H27F3O4

C28H27F3O4

Conditions
ConditionsYield
With (1,2-dimethoxyethane)dichloronickel(II); lithium perchlorate; potassium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl-formamide at 20℃; Electrochemical reaction; Inert atmosphere; Glovebox;86%
1,1,1-trifluoro-2-chloroethane
75-88-7

1,1,1-trifluoro-2-chloroethane

fenofibrate
49562-28-9

fenofibrate

isopropyl 2-methyl-2-(4-(4-(2,2,2-trifluoroethyl)benzoyl)phenoxy)propanoate

isopropyl 2-methyl-2-(4-(4-(2,2,2-trifluoroethyl)benzoyl)phenoxy)propanoate

Conditions
ConditionsYield
With 4,4'-di-tert-butyl-2,2'-bipyridine; magnesium chloride; nickel dibromide; zinc In N,N-dimethyl acetamide at 80℃; for 12h; Inert atmosphere; Schlenk technique;85%

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