Memantine HCl Basic information Product Name: Memantine HCl Synonyms: MEMANTINE HCL;LABOTEST-BB LT00233220;1,3-Dimethyl-5-aminoadamantane hydrochloride;1,3-DIMETHYLAMINOADAMANTANE HYDROCHLORIDE;1-AMINO-3,5-DIMETHYLADAMANTANE HCL;1-AMINO-3,5-DI
SICHUAN ZHONGBANG with its subsidiaries LUZHOU FUBANG& LUZHOU DAZHOU are specializing in the research, development, manufacturing and trade of fine chemicals, pesticide intermediates and pharmaceutical intermediates.
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryItems Standard Result Assay 98%min ----------------------------------------------------------------------------------------------
Cas:41100-52-1
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inquiryHebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ
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Min.Order:100 Gram
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Min.Order:1 Gram
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inquirywhite powder Molecular formula:C12H21NHCL Molecular weight:215.81 Cas:41100-52-1 Appearance:White crystal or powder Melting range:290οC-295οC Loss on drying:≤0.5% Content:≥98.5%(HPLC) Appearance:White or almost
Cas:41100-52-1
Min.Order:25 Kilogram
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Type:Trading Company
inquiryT he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White
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Min.Order:1 Gram
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
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inquiryMemantine HCl Basic information Description References Product Name: Memantine HCl Synonyms: MEMANTINE HCL;LABOTEST-BB LT00233220;1,3-Dimethyl-5-aminoadamantane hydrochloride;1,3-DIMETHYLAMINOADAMANTANE HYDROCHLORIDE;1-AMINO-3,5-DIMETHYLADAMANTANE
Memantine HCl Basic information Product Name: Memantine HCl Synonyms: MEMANTINE HCL;LABOTEST-BB LT00233220;D-145;1,3-Dimethyl-5-aminoadamantane hydrochloride;1,3-DIMETHYLAMINOADAMANTANE
Cas:41100-52-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
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Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiryAppearance: White Crystal Storage:Store in cool and dry place, away from sun light. Package:drum Application:pharmaceutical Transportation:By sea or by ai r Port:Qingdao Port
Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
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inquiry1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White powder Storage:storage in a dr
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Min.Order:1 Gram
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Type:Lab/Research institutions
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Min.Order:10 Gram
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Type:Trading Company
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Type:Trading Company
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Cas:41100-52-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Min.Order:1 Kilogram
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Cas:41100-52-1
Min.Order:10 Gram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry2,2,2-trichloroethyl 3,5-dimethyladamantylcarbamate
memantine hydrochloride
Conditions | Yield |
---|---|
Stage #1: 2,2,2-trichloroethyl 3,5-dimethyladamantylcarbamate With acetic acid; zinc at 20℃; for 2h; Stage #2: With acetyl chloride In methanol at 40℃; for 16h; Heating; | 100% |
1-acetamido-3,5-dimethyladamantane
memantine hydrochloride
Conditions | Yield |
---|---|
Stage #1: 1-acetamido-3,5-dimethyladamantane With sodium hydroxide In diethylene glycol for 6h; Reflux; Stage #2: With water In dichloromethane; diethylene glycol at 20℃; for 0.25h; Stage #3: With hydrogenchloride In ethyl acetate at 0 - 30℃; for 6h; | 99.3% |
Stage #1: 1-acetamido-3,5-dimethyladamantane With potassium hydroxide; butan-1-ol at 20 - 132℃; for 10.33 - 10.5h; Stage #2: With hydrogenchloride In water at 20 - 25℃; for 0.666667h; | 95% |
Stage #1: 1-acetamido-3,5-dimethyladamantane With sodium hydroxide In ethylene glycol at 150 - 160℃; for 0.5h; Large scale; Stage #2: With hydrogenchloride In ethyl acetate Large scale; | 82.78% |
Conditions | Yield |
---|---|
Stage #1: 3,5-dimethyl-1-bromoadamantane; urea In 1-methyl-pyrrolidin-2-one at 120℃; for 4h; Stage #2: With sodium hydroxide In 1-methyl-pyrrolidin-2-one at 120℃; for 6h; Stage #3: With hydrogenchloride In 1-methyl-pyrrolidin-2-one; water at 25℃; for 16h; Solvent; Temperature; | 97% |
1-formamido-3,5-dimethyltricyclo[3.3.1.13,7]decane
memantine hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In water at 100℃; for 5h; | 94% |
Stage #1: 1-formamido-3,5-dimethyltricyclo[3.3.1.13,7]decane With water; sodium hydroxide In methanol for 12h; Reflux; Stage #2: With hydrogenchloride In methanol; n-heptane at 60 - 65℃; Product distribution / selectivity; | 86% |
With hydrogenchloride In hexane; water for 2.5h; Reflux; | 84.65% |
N-((1,3,5,7)-3,5-dimethyladamantan-1-yl)-1,1,1-trifluoromethanesulfonamide
memantine hydrochloride
Conditions | Yield |
---|---|
Stage #1: N-((1,3,5,7)-3,5-dimethyladamantan-1-yl)-1,1,1-trifluoromethanesulfonamide With potassium carbonate; 1-bromomethyl-4-nitro-benzene In acetone at 20℃; Stage #2: With caesium carbonate In tetrahydrofuran at 50℃; for 14h; Stage #3: With hydrogenchloride In tetrahydrofuran; water | 92% |
memantine*
memantine hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In water; acetone at -5 - 30℃; for 5h; | 91.9% |
With hydrogenchloride pH=6; Gas phase; | 88% |
With hydrogenchloride In water; acetone at 0 - 10℃; Solvent; | 88% |
1-nitro-3,5-dimethyl-adamantane
memantine hydrochloride
Conditions | Yield |
---|---|
Stage #1: 1-nitro-3,5-dimethyl-adamantane With iron; acetic acid at 20℃; for 4.5h; Stage #2: With hydrogenchloride In ethyl acetate for 0.5h; | 449.2 g |
memantine hydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: ammonia / dichloromethane; water / 0.5 h / 25 - 30 °C / pH 9.5 - 10.0 2.1: sodium hydroxide / diethylene glycol / 10 h / Heating / reflux 2.2: 2 h / 10 - 15 °C View Scheme |
3, 5-dimethyl-1-adamantyl methyl ketone
memantine hydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: methanol; O-benzenesulfonyl-acetohydroxamic acid ethyl ester; toluene-4-sulfonic acid / 12 h / Inert atmosphere; Reflux 2: hydrogenchloride / acetone / 3 h / 23 °C / Inert atmosphere View Scheme |
7-bromoheptyl alcohol
memantine hydrochloride
7-((3,5-dimethyladamantan-1-yl)amino)heptan-1-ol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 92% |
5-Chlorovaleroyl chloride
memantine hydrochloride
5-chloro-N-(3,5-dimethyladamantan-1-yl)pentanamide
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 20℃; for 4h; | 91% |
memantine hydrochloride
Conditions | Yield |
---|---|
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; | 91% |
acetyl chloride
memantine hydrochloride
1-acetamido-3,5-dimethyladamantane
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 3h; Solvent; | 91% |
9-bromononan-1-ol
memantine hydrochloride
9-((3,5-dimethyladamantan-1-yl)amino)nonan-1-ol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 90% |
formic acid
memantine hydrochloride
1-formamido-3,5-dimethyltricyclo[3.3.1.13,7]decane
Conditions | Yield |
---|---|
With titanium sulfate at 80℃; for 5h; Reagent/catalyst; Temperature; | 90% |
N,N-dimethyl-formamide
memantine hydrochloride
1-formamido-3,5-dimethyltricyclo[3.3.1.13,7]decane
Conditions | Yield |
---|---|
With titanium(IV) oxide at 105℃; for 3h; Reagent/catalyst; | 90% |
acetic anhydride
memantine hydrochloride
1-acetamido-3,5-dimethyladamantane
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 2.5h; Solvent; | 90% |
1-bromo-6-hexanol
memantine hydrochloride
6-((3,5-dimethyladamantan-1-yl)amino)hexan-1-ol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 89% |
ethyl 2-isothiocyanatoacetate
memantine hydrochloride
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide at 80℃; for 12h; | 89% |
5-tosyloxy-3-oxapentanol
memantine hydrochloride
2-(2-((3,5-dimethyladamantan-1-yl)amino)ethoxy)ethanol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 88% |
2-((2-hydroxyethyl)thio)ethyl 4-methylbenzenesulfonate
memantine hydrochloride
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 87% |
memantine hydrochloride
Glycine ethyl ester isocyanate
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide at 20℃; for 12h; | 87% |
memantine hydrochloride
toluene-4-sulfonic acid 4-tert-butoxycarbonylaminobutyl ester
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide under 12929 Torr; for 1h; Microwave irradiation; | 87% |
8-bromooctanol
memantine hydrochloride
8-((3,5-dimethyladamantan-1-yl)amino)octan-1-ol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 48h; | 86% |
memantine hydrochloride
4-Chlorobutanoyl chloride
4-chloro-N-(3,5-dimethyladamantan-1-yl)butanamide
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 20℃; for 4h; | 86% |
formamide
memantine hydrochloride
1-formamido-3,5-dimethyltricyclo[3.3.1.13,7]decane
Conditions | Yield |
---|---|
With copper(II) choride dihydrate at 40℃; for 4h; | 86% |
6-chlorohexanoyl chloride
memantine hydrochloride
6-chloro-N-(3,5-dimethyladamantan-1-yl)hexanamide
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 20℃; for 4h; | 85% |
9-bromononanoic acid
memantine hydrochloride
Conditions | Yield |
---|---|
With 2-chloro-1,3-dimethyl-4,5-dihydro-1H-imidazolium chloride; triethylamine In dichloromethane at 0 - 20℃; for 18h; | 85% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Cooling with ice; | 81% |
3-(prop-2-en-1-yldisulfanyl)propanoic acid
memantine hydrochloride
3-(prop-2-en-1-yldisulfanyl)-N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)propanamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Cooling with ice; | 79% |
memantine hydrochloride
6-((tert-butoxycarbonyl)amino)hexyl 4-methylbenzenesulfonate
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide under 12929 Torr; for 1h; Microwave irradiation; | 79% |
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