A novel Schiff base polymer containing phenol group, Poly(3-[[4-(dimethylamino)benzylidene]amino]phenol) P(3-DBAP), was prepared by oxidative polycondensation reaction of 3-[[4-(dimethylamino)benzylidene]amino]phenol (3-DBAP) using NaOCl, H2O2, O2 oxidants in aqueous alkaline medium. Yield and m...

Antioxidants, particularly those designed for use in hydrocarbon media, suffer from a variety of limitations including high volatility and poor solubility. Using 2,2-bis(hydroxymethyl)propionic acid as the branching unit, a series of novel dendrons featuring 3-(3,5-di-tert-butyl-4-hydroxyphenyl)...

Phenol is one of the most widespread, toxic and recalcitrant compounds in water sources. Due to its persistent nature, conventional wastewater treatment methods are not effective to remove or degrade phenol from water. In this work, novel photocatalysts were developed to effectively degrade phen...

Selective inhibition of cyclooxygenase (COX)-2 enzyme is an important achievement when looking for potent anti-inflammatory agents, with fewer gastrointestinal side effects. In this work, a new series of cinnamic acid derivatives, namely hexylamides, have been designed, synthesized and evaluated...

Multitarget ligands (MTL) based on sterically hindered phenol and containing a quaternary ammonium moiety (SHP-n-Q) were synthesized. These compounds are inhibitors of cholinesterases with antioxidant properties. The inhibitory selectivity is 10-fold potent for BChE than for AChE. IC50 of SHP-n-...

3-(Dimethylamino)phenol (3-DMAP) exists in the environment as a transformation product of ureic herbicides and may also be considered as a derivative of phenoxyherbicides.In this study, the activity of glutathione peroxidase, catalase and superoxide dismutase, as well as the level of free radica...

Pyrenebutylamidopropylimidazole 1 was synthesized as a sensor for 3,5-dinitrosalicylic acid (3,5-DNSA) and 5-nitrosalicylic acid (5-NSA), among other aromatic carboxylic acids, and Hg2+ among different metal ions in PBS-EtOH (5:95; pH=7.4) solutions. The sensing ability of probe 1 was examined u...

The metabolic fate of carboxyl 14C-diiodosalicylic acid (DIS) was studied in cattle and rats. In three trials with cattle, approximately 95% of 14C was excreted via the urine within ten days of dosing. Diiodosalicylic acid and 5-iodosalicylic acid were the only metabolites in cattle urine, with ...

In the search for poorly soluble bupivacaine salts potentially enabling prolonged postoperative pain relief after local joint administration in the form of suspensions the solubility of bupivacaine salts of diflunisal and other aromatic hydroxycarboxylic acids were investigated together with the...

Transthyretin (TTR) is a plasma homotetrameric protein associated with senile systemic amyloidosis and familial amyloidotic polyneuropathy. In theses cases, TTR dissociation and misfolding induces the formation of amyloidogenic intermediates that assemble into toxic oligomeric species and lead t...

A method for the determination of the sodium salt of 5-iodosalicyhc acid (5-I-S-Na) and total iodine is described. The method for the determination of 5-T-S-Na is based on the ultraviolet light absorption of this substance. Control experiments with the method for the determination of 5-1-S-Na an...

In this study, 5-iodosalicylic acid (5-ISA, C7H5IO3) is structurally characterized by FT-IR, FT-Raman, NMR and UV spectroscopies. There are eight conformers, Cn, n = 1–8 for this molecule therefore the molecular geometry for these eight conformers in the ground state are calculated by using the...

The aim of the study was to determine the effect of various doses of 5-iodosalicylic acid (5I-SA; organoiodine compound) on the growth, chemical composition, and efficiency of iodine biofortification of lettuce cultivated in a nutrient film technique hydroponic system. The additional purpose was...

Browning and growth of food-borne pathogens during postharvest storage are major factors that reduce the quality and economic value of fresh-cut apples. Previous studies suggest that exogenous γ-aminobutyric acid (GABA) has a significant role in multiple physiological processes in plants. This ...

The effects of postharvest malic acid (MA) treatment on alleviating the occurrence of chilling injury (CI) symptoms in banana (Musa spp., AAA group, cv. Brazil) fruit under 6 °C were evaluated. Application of 80 mM MA alleviated CI symptoms (surface browning), delayed the decrease in chlorophyl...

This study aimed to investigate the effects of acidic electrolyzed oxidizing water (AEW) treatment on storability and metabolism of reactive oxygen species (ROS) in blueberries cv. ‘Brightwell’ during storage at 4 °C. Results showed that, compared with the control blueberries, AEW treated-blu...

Glucose sulfonic acid (GSA) was synthesized for the first time and used as an efficient catalyst for the preparation of tetrahydrobenzo[α]xanthens and tetrahydrobenzo[α]acridines via the reaction of aromatic aldehydes, 2-naphthol (or β-naphthylamine), and dimedone in water. Up to four new bon...

The phytohormone jasmonic acid (JA) plays an imperative role in plants by modulating the activity of their antioxidative defense system under stress conditions. Here, we explored the role of JA-induced alterations in the growth and transcript levels of antioxidative enzymes in tomato seedlings e...

Synthesis of substituted 10,10-dimethyl-7-phenyl-9,10,11,12-tetrahydrobenzo[c]acridin-8(7H)-one derivatives proceeded by the one-pot reaction of aromatic aldehydes, 5,5-dimethylcyclohexane-1,3-dione (dimedone) and 1-naphthylamine, in the presence of Succinimide-N-sulfonic acid (SuSA) has been re...

Background2,4-Dinitrophenol (DNP) is a known uncoupler of oxidative phosphorylation that clinically results in hyperthermia, tachycardia, tachypnea, and metabolic acidosis. Overdoses of DNP are often fatal and there is no specific reversal therapy. Dantrolene interferes with calcium release in s...