A solid phase synthesis towards structural analogs of fumitremorgins, verruculogens and tryprostatins using a cyclization/cleavage strategy was developed. To grove the general applicability of the route, a representative set of 42 single compounds (as diastereomeric mixtures) was prepared by par...

The total synthesis of the tremorgenic mycotoxin Verruculogen TR-2 (6) is presented. Selective oxidation of 1 to yield 3 or 4 was achieved using 2. Compound 4 was elaborated to the title compound employing osmium tetroxide.

[14C1 Verruculogen (75 Mg/kg) was given intravenously to a sheep under barbiturate anaesthesia to prevent the severe tremor and convulsions which would otherwise have occurred. Two hours later 28 per cent of the tremorgenic mycotoxin was detected in the liver, bile and small intestine. Approxima...

SummaryThe cytokinins, benzyl adenine, kinetin, isopentenyl adenine, and zeatin and the cytokinin analogue, ancymidol all inhibited the biosynthesis of abscisic acid from mevalonic acid in mesocarp tissue from ripe fruits of avocado (Persea gratissima).

SummaryAMO-1618 and ancymidol, inhibitors of gibberellin biosynthesis, retarded germination of Amaranthus caudatus L. seeds, ancymidol being more active than AMO-1618. Transfer of seeds to ancymidol after imbibition in water for 12 h caused inhibition of germination. Longer imbibition in water l...

Rooted cuttings of poinsettia (Euphorbia pulcherrima Willd.) propagated in Oasis® Rootcubes® were pre-treated by direct application of ancymidol (α-cyclopropyl-α-(4-methoxyphenyl)-5-pyrimidinemethanol) or chlormequat (2-chloroethyl-trimethylammonium chloride) to cubes prior to planting. Soil d...

Ancymidol [α-cyclopropyl-α-(4-methoxyphenyl)-5-pyrimidinemethanol] was applied to commercially pre-cooled bulbs of Lilium cultivar ‘Gold Nugget’ at 0, 0.25, 0.5 or 1 mg per bulb as a bulb dip prior to planting, as a soil drench at planting or at shoot emergence of 2–3 cm. Bulb dips resulted...

Experiments were conducted to determine the effect of ancymidol, as impacted by temperature, Ca(NO3)2, and cultivar, on the prevention of Ca deficiency symptoms during hydroponic forcing of tulip (Tulipa gesneriana L.). In all treatments where tulips were forced in distilled water, Ca deficiency...

Publisher SummaryThis chapter provides the basic synthesis paths routes for the manufacture of ancymidol, with a listing of the main raw materials and intermediates used in the synthesis of ancymidol. Ancymidol is commercially known as A-Rest or Reducymol, and it belongs to the pyrimidine group.

Sulfane sulfur species are newly recognized signaling molecules that play physiological roles in many biological events. The development of new technologies for the detection of sulfane sulfurs is important. Point-of-care (POC) devices are in-field rapid and low-cost detectors that are more conv...

The article focuses on the study of microclimate conditions under bridge structures and their influence on the characteristics of corrosion products developed on the surface of structures designed from weathering steels. The development of a protective corrosion product layer on weathering steel...

A method for the synthesis of 5-fluoro- and 5-bromoalkylisoxazoles via nitrosation of alkylated gem-dihalocyclopropanes with a nitrosyl chloride sulfur trioxide adduct has been developed. In the case of bromofluorocyclopropanes the reaction proceeded with excellent chemoselectivity thus providin...

A novel metal-free synthesis of 2-substituted benzothiazoles from easily available o-chloronitrobenzenes and benzyl chlorides using elemental sulfur as traceless oxidizing agent has been developed. The protocol provides a simple, efficient, and atom-economic way to access to benzothiazoles in mo...

An efficient one-pot three-component reaction of 2-iodoanilines, benzyl chlorides and elemental sulfur to form 2-substituted benzothiazoles in satisfactory yields (up to 98%) has been described. The reaction tolerated a wide range of functional groups on the aromatic ring. And heterocycle methyl...

The search for halotolerant acidophilic microorganisms to increase the efficiency of bioleaching processes in regions of fresh water scarcity has been ongoing for the past two decades. In this study, three pure cultures (V6, V8 and M8) and four enrichment cultures (14C, L2-21, L4-9 and L6-11) fr...

The dissolution of chalcopyrite in 0.2 M sulfuric acid solutions with different sodium chloride concentrations was investigated. Different anodic potentials were applied, and the behavior of the electrode was observed using potentiodynamic, cyclic voltammetry (CV), and electrochemical impedance ...

This study aims to investigate the influence of the slag content on the chloride and sulfuric acid resistances of alkali-activated fly ash/slag (AFS) paste. A series of tests were conducted to examine the effects of reaction products and their contents on the chloride and sulfuric acid resistanc...

Thionyl chloride is often used to convert alcohols into more reactive alkyl chloride, which can be easily converted to many compounds that are not possible from alcohols directly. One important reaction of alkyl chloride is nucleophilic substitution, which is typically conducted under basic cond...

The paper shows that modification of amorphous silica with aluminum chloride leads to an increase in number of active sites on the surface of amorphous silica. The physical chemical and quantum chemical studies showed the chemical interaction between sulfur and aluminum (attached to the surface ...

ABSTRACTIn this study, different properties of different types of absorable and nonabsorable sutures are investigated. For this purpose, two numbers of four different sutures and three sutures with two different counts were tested. These sutures are Biosyn, Caprosyn, Polysorb, Novafil and Surgip...