In this work, we investigate the thermoluminescence emission in the temperature range 70 °C–220 °C for different types of quartz, both natural and synthetic. We focus on three thermoluminescence peaks, the so called 110 °C one, which we detect at around 85 °C (5 °C/s), and the two intermed...

Studies were carried on the decolorization of the textile dye reactive blue 220 (RB220) by a novel isolate of Lentinus crinitus fungi. The optimal conditions for the production of destaining activity were obtained in media containing intermediate concentrations of ammonium oxalate and glucose (1...

The metabolic fate of aprophen* hydrochloride (2-diethyl-aminoethyl 2,2-diphenylpropionate) was studied in rats after intravenous administration. Both 14C-labeled and unlabeled aprophen were used in these studies. Blood samples were collected and analyzed to determine the identities of the metab...

An isosteric analog of 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG), 9-[[(ethoxyhydroxyphosphinyl)methoxy]methoxy]guanine (SKI 1008), was evaluated for its in vitro antiviral activity against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), murine cytomegalovirus (MCMV), and human cytomega...

The purine salvage enzyme, hypoxanthine–guanine–(xanthine) phosphoribosyltransferase [HG(X)PRT], catalyses the synthesis of the purine nucleoside monophosphates, IMP, GMP or XMP essential for DNA/RNA production. In protozoan parasites, such as Plasmodium, this is the only route available for t...

In this study, we investigated the interaction between Lactobacillus pentosus HC-2 and Vibrio parahaemolyticus E1 when cocultured in Litopenaeus vannamei in vivo and in vitro. Fluorescence microscopy was used to observe the distribution of these two strains, which were labeled with DAPI and CFDA...

The hair-dye ingredients, HC Blue No. 1 (HCB1) and HC Blue No. 2 (HCB2), were tested for the induction of bacterial mutation using Salmonella typhimurium strains TA1535, TA1537, TA98 and TA100; and Escherichia coli strains WP2uvrA−. In addition, both dyes were evaluated in the mouse lymphoma L51...

SummaryPrussian blue analogs have significant promise as active materials for the next generation of battery electrodes with improved cycle life and rate capability. Their useful electrochemical properties include two independent redox centers per unit cell; a nanoporous, open framework for rapi...

Technical, economic, social and environmental conditions are turning natural gas into a feasible solution for sustainable transportation systems in the State of São Paulo (Brazil). Blue Corridors are routes that aim to enable the use of liquefied natural gas (LNG) for heavy vehicles as a substit...

In this study, magnetic graphene oxide (MGO) was used as an adsorbent for effective removal of methylene blue (MB) from aqueous solution. Graphene oxide (GO) nanosheets were synthesized using improved hummer method and magnetized electrochemically using iron electrodes by applying different curr...

Detecting epistatic interactions, or nonlinear interactive effects of Single Nucleotide Polymorphisms (SNPs), has gained increasing attention in explaining the “missing heritability” of complex diseases. Though much work has been done in mapping SNPs underlying diseases, most of them constrain...

Toxicology and carcinogenesis studies of 2 structurally-related p-phenylenediamines, HC Blue No. 1, and HC Blue No. 2 were conducted by administering each chemical in feed for 103 weeks to both sexes of Fischer 344/N rats and B6C3F1 (C57BL/6N × C3H/HEN) mice. Diets containing 0, 1500, or 3000 p...

Reformed exhaust gas recirculation (REGR), which can generate onboard hydrogen-rich gas (i.e., the reformate including H2, CO, unreformed hydrocarbon, etc.) via catalytic reforming of fuel and engine exhaust gas, is an attractive way to improve the performance and emissions characteristics of th...

In order to understand the mediation function of surface proteins in probiotic effects executed by Lactobacillus pentosus HC-2 in midgut of Litopenaeus vannamei, the immune and digestion related enzymes and the transcriptome expression were analyzed after shrimp fed with normal HC-2 or with stri...

Our previous work showed that Lactobacillus pentosus HC-2 has high antibacterial and adhesion activity, and as a probiotic could improve the nutrients and immunomodulatory effects in the Litopenaeus vannamei farming. In order to further investigate the influence of HC-2 surface protein on its pr...

Although lung adenocarcinoma patients have benefited from the development of targeted therapy, patients with lung squamous cell carcinoma (SqCC) have no effective treatment due to the complexity and heterogeneity of the disease. Therefore, basing on the genetic analysis of mutations in lung squa...

The inhibition of neuronal and inducible nitric oxide synthases (nNOS and iNOS) by a series of 36 indazoles has been evaluated, showing that most of the assayed derivatives are better iNOS than nNOS inhibitors. A parabolic model relating the iNOS inhibition percentage with the difference, Erel, ...

New synthetic approaches to fluorinated indazoles, as well as the features of their biological properties are presented and discussed in the frames of this review article.

A comprehensive study was performed for the first time to compare two structurally related substance classes, namely indazole-5-carboxamides (11–16) and (indazole-5-yl)methanimines (17–22). Both chemical entities are potent, selective and reversible MAO-B inhibitors and, therefore, may serve a...

Indazoles is an important class of heterocyclic compounds having a wide range of biological and pharmaceutical applications. There is enormous potential in the synthesis of novel heterocyclic systems to be used as building blocks for the next generation of pharmaceuticals as anti-bacterial, anti...