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EAST CHEMSOURCES LIMITED

Methyl dichloroacetate Product name: Methyl dichloroacetate Alias: Dichloroacetic acid methyl ester CAS NO.: 116-54-1 Molecular formula: C3H4Cl2O2

Methyl dichloroacetate

Cas:116-54-1

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl dichloroacetate

Cas:116-54-1

Min.Order:1

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

Methyldichloroacetate

Cas:116-54-1

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methyl dichloroacetate

Cas:116-54-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

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Hebei yanxi chemical co.,LTD.

1 Factory price 2 High quality 3 Good service 4 Prompt service Appearance:The crystallization Storage:Kept in dry and cool place and from sunlight; Kept the packing intact. Package: 25kg plastic woven bag with inner linning. Application: Food

Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:100 Kilogram

FOB Price: $1000.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--116-54-1--Dichloroacetic acid methyl ester factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable bu

TIANFUCHEM--116-54-1--Dichloroacetic acid methyl ester factory price

Cas:116-54-1

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

[Product name]: Methyldichloroacetate [CAS number]: 116-54-1 [Molecular formula]: C3H4Cl2O2 [Molecular weight]: 142.97 [RTECS number]: AG6625000 [UN Code]: 2299 [Dangerous Goods Code]: 61612 [IMDG Rule Page]: 6195 [Appearance and properties

Methyl Dichloroacetate

Cas:116-54-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

99% Dichloroacetic Acid Methyl ester CAS:116-54-1

Cas:116-54-1

Min.Order:10 Gram

Negotiable

Type:Other

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

MethyldichloroacetateCAS NO.: 116-54-1

Cas:116-54-1

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Manufacturers

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colorless transparent liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceuti

Methyldichloroacetate

Cas:116-54-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:0

Negotiable

Type:Manufacturers

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Methyl Dichloroacetate

Cas:116-54-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers539.Safe and fa

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Methyl Dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Manufacturers

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 116-54-1 with competitive price

Cas:116-54-1

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Methyl dichloroacetate

Cas:116-54-1

Min.Order:0

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Type:Other

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Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Methyl dichloroacetate 116-54-1

Cas:116-54-1

Min.Order:0

Negotiable

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Beantown Chemical

in stock Application:116-54-1

Methyl dichloroacetate, 99%

Cas:116-54-1

Min.Order:0

Negotiable

Type:Trading Company

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Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

Methyl 2,2-dichloroacetate

Cas:116-54-1

Min.Order:0

Negotiable

Type:Other

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#116-54-1;CAT#A803640

Cas:116-54-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

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HENAN SUNLAKE ENTERPRISE CORPORATION

1. ISO 9001 approved, GMP producing standard,Proffesional QA system, our quality is guaranteed. 2. Facotory direct sale, most comptive price ensured; 3. Audited Supplier on lookchem, No trick, No Scam! 4. Enough stock can make sure safe deliv

Offer 116-54-1 C3H4Cl2O2 Dichloroacetic acid methyl ester

Cas:116-54-1

Min.Order:1 Kilogram

FOB Price: $750.0 / 850.0

Type:Trading Company

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Synthetic route

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
In hydrogenchloride94.3%
methanol
67-56-1

methanol

pentachloroacetone
1768-31-6

pentachloroacetone

A

chloroform
67-66-3

chloroform

B

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With calcinated sodium carbonate for 2h; Heating;A n/a
B 85.4%
n-hexan-2-one
591-78-6

n-hexan-2-one

Methyl trichloroacetate
598-99-2

Methyl trichloroacetate

A

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

B

dimethyl tetrachlorosuccinate
3875-95-4

dimethyl tetrachlorosuccinate

C

methyl 3-methyl-2-chlorohept-2-enoate

methyl 3-methyl-2-chlorohept-2-enoate

Conditions
ConditionsYield
With iodine; iron pentacarbonyl In benzene for 2h; Condensation; Heating;A 6%
B 10%
C 80%
carbonic acid dichloromethyl ester 1-ethoxy-ethyl ester

carbonic acid dichloromethyl ester 1-ethoxy-ethyl ester

triethyl phosphite
122-52-1

triethyl phosphite

A

diethyl 1-ethoxyethylphosphonate

diethyl 1-ethoxyethylphosphonate

B

triethyl phosphate
78-40-0

triethyl phosphate

C

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
at 50 - 80℃; for 4.5h; Title compound not separated from byproducts;A n/a
B n/a
C 28%
Methyl trichloroacetate
598-99-2

Methyl trichloroacetate

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With copper acetylacetonate; methyl phosphite at 150℃;21%
Methyl trichloroacetate
598-99-2

Methyl trichloroacetate

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With copper acetylacetonate at 100 - 150℃;21%
dichloro-acetic acid
79-43-6

dichloro-acetic acid

methane
34557-54-5

methane

trifluoroacetic acid
76-05-1

trifluoroacetic acid

A

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

B

trifluoroacetic acid-methyl ester
431-47-0

trifluoroacetic acid-methyl ester

Conditions
ConditionsYield
With ammonium iodate; potassium chloride In water under 2585.81 Torr; for 24h; Pressure; Photolysis; Sealed tube;A 17%
B 16%
methanol
67-56-1

methanol

dichloro-acetic acid
79-43-6

dichloro-acetic acid

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid
With hydrogenchloride
methanol
67-56-1

methanol

chloral hydrate
302-17-0

chloral hydrate

potassium cyanide
151-50-8

potassium cyanide

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

methanol
67-56-1

methanol

2,2-diacetoxy-1,1,1-trichloro-ethane
24298-56-4

2,2-diacetoxy-1,1,1-trichloro-ethane

potassium cyanide
151-50-8

potassium cyanide

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

magnesium methanolate
109-88-6, 16436-83-2, 16436-85-4

magnesium methanolate

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With methanol; Petroleum ether
dichloro-malonic acid monomethyl ester
108676-75-1

dichloro-malonic acid monomethyl ester

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
beim Erhitzen;
methanol
67-56-1

methanol

potassium cyanide
151-50-8

potassium cyanide

chloral
75-87-6

chloral

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

dichloro-acetic acid
79-43-6

dichloro-acetic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
at 200℃;
With tetra(n-butyl)ammonium hydrogensulfate; sodium sulfate In water at 55℃; Methylation; esterification;
methanol
67-56-1

methanol

trichloroacetic acid
76-03-9

trichloroacetic acid

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With zinc Behandeln des Reaktions-gemisches mit konz. Schwefelsaeure;
methanol
67-56-1

methanol

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2-chloro-1,1,2-trifluoroethyl methyl ether
425-87-6

2-chloro-1,1,2-trifluoroethyl methyl ether

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid; silica gel
methanol
67-56-1

methanol

chloromethyl dichloroacetate
3338-76-9

chloromethyl dichloroacetate

A

chloromethanol
15454-33-8

chloromethanol

B

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With perchloric acid; sodium perchlorate; water at 25℃; Rate constant; Mechanism;
methanol
67-56-1

methanol

4-nitrophenyl 2,2-dichloroacetate
780-32-5

4-nitrophenyl 2,2-dichloroacetate

A

4-nitro-phenol
100-02-7

4-nitro-phenol

B

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
pyridine at 25.1℃; Rate constant; Thermodynamic data; also with 2,6-dimethylpyridine; kobs, k1, k2; ΔH(excit), ΔS(excit.);
methanol
67-56-1

methanol

1,2,2-trichloro-1-acetoxyethene
145285-72-9

1,2,2-trichloro-1-acetoxyethene

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
for 0.5h; Heating;
dichloro-acetic acid
79-43-6

dichloro-acetic acid

3,5-Dichloro-3,5-bis-chloromethyl-[1,2,4]trioxolane

3,5-Dichloro-3,5-bis-chloromethyl-[1,2,4]trioxolane

A

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

B

methyl chloroacetate
96-34-4

methyl chloroacetate

Conditions
ConditionsYield
1) CDCl3, 60 deg C, 7 d; 2) 30 min; Yield given. Multistep reaction. Yields of byproduct given;
1,1-dichloro-2,2-dimethoxy-ethene
69814-51-3

1,1-dichloro-2,2-dimethoxy-ethene

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride; water In [D3]acetonitrile
methanol
67-56-1

methanol

3,5,5-Trimethyl-4,5-dihydro-pyrazole-1-carboxylic acid (2,2-dichloro-acetyl)-amide
129309-01-9

3,5,5-Trimethyl-4,5-dihydro-pyrazole-1-carboxylic acid (2,2-dichloro-acetyl)-amide

A

3,5,5-trimethyl-4,5-dihydro-1H-pyrazole-1-carboxamide
3786-02-5

3,5,5-trimethyl-4,5-dihydro-1H-pyrazole-1-carboxamide

B

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
Heating;
3,5,5-Trimethyl-4,5-dihydro-pyrazole-1-carboxylic acid (2,2-dichloro-acetyl)-amide
129309-01-9

3,5,5-Trimethyl-4,5-dihydro-pyrazole-1-carboxylic acid (2,2-dichloro-acetyl)-amide

A

3,5,5-trimethyl-4,5-dihydro-1H-pyrazole-1-carboxamide
3786-02-5

3,5,5-trimethyl-4,5-dihydro-1H-pyrazole-1-carboxamide

B

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With methanol Heating;
trichlorofluoroethene
359-29-5

trichlorofluoroethene

sodium methylate
124-41-4

sodium methylate

A

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

B

1,1-dichloro-2,2,2-trimethoxyethane
141739-71-1

1,1-dichloro-2,2,2-trimethoxyethane

C

2,2-Dichloro-1-fluorovinyl methyl ether
433-50-1

2,2-Dichloro-1-fluorovinyl methyl ether

Conditions
ConditionsYield
In methanol at 40 - 50℃; for 0.333333h;
trans-form of 1.2-dichloro-1-bromo-ethene
157672-80-5

trans-form of 1.2-dichloro-1-bromo-ethene

sodium methylate
124-41-4

sodium methylate

A

methyl bromide
74-83-9

methyl bromide

B

methylene chloride
74-87-3

methylene chloride

C

1,2-dichloro-1-methoxy-ethene
42345-81-3

1,2-dichloro-1-methoxy-ethene

D

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

E

methyl chloroacetate
96-34-4

methyl chloroacetate

F

(E)-1-Bromo-1,2-dichloro-2-methoxy-ethene

(E)-1-Bromo-1,2-dichloro-2-methoxy-ethene

Conditions
ConditionsYield
In acetonitrile for 1h; Product distribution; Ambient temperature; various nucleophiles;
methanol
67-56-1

methanol

dichloroacetamide
683-72-7

dichloroacetamide

boron trifluoride
7637-07-2

boron trifluoride

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
anfangs unter Eiskuehlung;
methyl iodide
74-88-4

methyl iodide

silver-dichloroacetate

silver-dichloroacetate

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Conditions
ConditionsYield
With benzene
acetaldehyde
75-07-0

acetaldehyde

1-ethoxyethyl dichloroethanoate

1-ethoxyethyl dichloroethanoate

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

A

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

B

O,O-dimethyl-1-(1-ethoxy)ethoxyethyl phosphonate
69054-02-0

O,O-dimethyl-1-(1-ethoxy)ethoxyethyl phosphonate

Conditions
ConditionsYield
at 50℃; for 19h;
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate
160727-95-7

methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate

Conditions
ConditionsYield
With sodium methylate In tert-butyl methyl ether at 20℃; for 3h; Heating / reflux;100%
With sodium methylate In tetrahydrofuran at 0 - 85℃; for 3h; Darzens Condensation;70%
With sodium methylate In tetrahydrofuran at 0 - 85℃; for 2.83333h; Darzens Condensation;70%
With potassium tert-butylate In tetrahydrofuran at -60 - 20℃;50%
With potassium tert-butylate In tetrahydrofuran at -78 - 20℃;
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2-(2-chlorophenyl)cyclopent-2-en-1-one

2-(2-chlorophenyl)cyclopent-2-en-1-one

methyl 6-chloro-1-(2-chlorophenyl)-2-oxobicyclo[3.1.0]hexane-6-carboxylate

methyl 6-chloro-1-(2-chlorophenyl)-2-oxobicyclo[3.1.0]hexane-6-carboxylate

Conditions
ConditionsYield
Stage #1: dichloroacetic acid methyl ester With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.75h; Inert atmosphere;
Stage #2: 2-(2-chlorophenyl)cyclopent-2-en-1-one In tetrahydrofuran at 23℃; Inert atmosphere;
100%
3-methoxy-4-(phenylmethoxy)benzaldehyde
2426-87-1

3-methoxy-4-(phenylmethoxy)benzaldehyde

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(E)-3-(3-methoxy-4-(benzyloxy)phenyl)methyl acrylate
93878-20-7

(E)-3-(3-methoxy-4-(benzyloxy)phenyl)methyl acrylate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;99%
m-bromobenzoic aldehyde
3132-99-8

m-bromobenzoic aldehyde

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

methyl m-bromocinnamate
79432-87-4

methyl m-bromocinnamate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;99%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

3-phenyl-propenal
104-55-2

3-phenyl-propenal

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;99%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

tert-butyl((5-iodopentyl)oxy)dimethylsilane
85514-45-0

tert-butyl((5-iodopentyl)oxy)dimethylsilane

C14H28Cl2O3Si

C14H28Cl2O3Si

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0℃; for 4h;99%
3-phenyl-propionaldehyde
104-53-0

3-phenyl-propionaldehyde

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

methyl (2E)-5-phenyl-2-pentenoate
26429-97-0

methyl (2E)-5-phenyl-2-pentenoate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;98%
With manganese In tetrahydrofuran for 3h; Heating;89%
With manganese In tetrahydrofuran for 3h; Reflux; Inert atmosphere; optical yield given as %de; stereoselective reaction;89%
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

methyl (2E)-3-(4-(trifluoromethyl)phenyl)prop-2-enoate
20754-22-7

methyl (2E)-3-(4-(trifluoromethyl)phenyl)prop-2-enoate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;98%
piperonal
120-57-0

piperonal

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

methyl (2E)-3-(1,3-benzodioxol-5-yl)acrylate
40918-96-5

methyl (2E)-3-(1,3-benzodioxol-5-yl)acrylate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;98%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2-Phenylpropanal
34713-70-7

2-Phenylpropanal

(E)-4-Phenyl-2-pentensaeure-methylester
64252-49-9

(E)-4-Phenyl-2-pentensaeure-methylester

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;98%
With manganese In tetrahydrofuran for 3h; Heating;85%
With manganese In tetrahydrofuran for 3h; Reflux; Inert atmosphere; optical yield given as %de; stereoselective reaction;85%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

3-(4-methoxy-phenyl)acrylic acid methyl ester
3901-07-3

3-(4-methoxy-phenyl)acrylic acid methyl ester

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;98%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

L-threo-chloramphenicol
134-90-7

L-threo-chloramphenicol

Conditions
ConditionsYield
In methanol at 70℃; for 2h;97.8%
In methanol for 3h; Reflux;80%
With methanol
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

chloramphenicol
56-75-7

chloramphenicol

Conditions
ConditionsYield
In methanol at 23 - 40℃; for 9h; Inert atmosphere;97%
at 90℃; for 1h;80%
Amidation;74%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

benzaldehyde
100-52-7

benzaldehyde

Methyl cinnamate
103-26-4

Methyl cinnamate

Conditions
ConditionsYield
With chromium dichloride In tetrahydrofuran at 20℃; for 12h;97%
With manganese In tetrahydrofuran for 3h; Heating;72%
With manganese In tetrahydrofuran for 3h; Reflux; Inert atmosphere; optical yield given as %de; stereoselective reaction;72%
With chloro-trimethyl-silane; zinc In tetrahydrofuran at 50℃; for 3h;70%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

2-chloro-3-p-tolyl-oxirane-2-carboxylic acid methyl ester

2-chloro-3-p-tolyl-oxirane-2-carboxylic acid methyl ester

B

methyl 3-chloro-3-(4-methylphenyl)-2-oxopropionate
191152-70-2

methyl 3-chloro-3-(4-methylphenyl)-2-oxopropionate

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at -80 - 20℃; for 17h; Darzens condensation;A n/a
B 97%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(d,l) isopropylidene glyceraldehyde
5736-03-8

(d,l) isopropylidene glyceraldehyde

methyl 2-chloro-3-(2,2-dimethyl-1,3-dioxolan-4-yl)oxirane-2-carboxylate

methyl 2-chloro-3-(2,2-dimethyl-1,3-dioxolan-4-yl)oxirane-2-carboxylate

Conditions
ConditionsYield
With potassium tert-butylate at 20℃; for 24h; Darzens condensation;97%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

dihydrocholesterone
566-88-1

dihydrocholesterone

3'-chlorospiro<5α-cholestan-3α:2'-oxirane>-3'-carboxylate de methyle
138192-85-5, 138207-52-0

3'-chlorospiro<5α-cholestan-3α:2'-oxirane>-3'-carboxylate de methyle

Conditions
ConditionsYield
With sodium methylate In methanol; diethyl ether at -15℃;96%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(1R,2S)-2-amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol
76639-93-5, 105182-37-4, 118015-48-8

(1R,2S)-2-amino-3-fluoro-1-<4-(methylsulphonyl)phenyl>-1-propanol

Florfenicol
73231-34-2

Florfenicol

Conditions
ConditionsYield
With triethylamine In methanol at 20℃;96%
With triethylamine In methanol for 18h; Ambient temperature;84%
With triethylamine for 3.5h; Heating; Yield given;
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2-chloro-4-fluorobenzaldehyde
84194-36-5

2-chloro-4-fluorobenzaldehyde

methyl 2-chloro-3-(2-chloro-4-fluorophenyl)oxirane-2-carboxylate

methyl 2-chloro-3-(2-chloro-4-fluorophenyl)oxirane-2-carboxylate

Conditions
ConditionsYield
With sodium t-butanolate In tetrahydrofuran at -78 - 20℃; for 3.5h; Darzens Condensation;96%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(1R,2R)-2-amino-1-<4-(methylsulphonyl)phenyl>-1,3-propanediol
51458-28-7

(1R,2R)-2-amino-1-<4-(methylsulphonyl)phenyl>-1,3-propanediol

thiamphenicol
15318-45-3

thiamphenicol

Conditions
ConditionsYield
With triethylamine In methanol at 30℃; for 8h; Inert atmosphere;95%
In methanol at 23 - 40℃; for 16h; Inert atmosphere;92%
With ethanol
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

threo (+/-)-2,2-dichloro-N-<2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl> acetamide
56-75-7, 134-90-7, 579-51-1, 2787-09-9, 3419-87-2, 7384-89-6, 7387-98-6, 50762-99-7, 126787-77-7, 140694-65-1

threo (+/-)-2,2-dichloro-N-<2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl> acetamide

Conditions
ConditionsYield
at 100 - 110℃; for 2h;95%
1-(4-methoxy-dibenzofuran-1-yl)-4-oxo-cyclohexane carbonitrile
1012335-47-5

1-(4-methoxy-dibenzofuran-1-yl)-4-oxo-cyclohexane carbonitrile

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2-chloro-6-cyano-6-(4-methoxy-dibenzofuran-1-yl)-1-oxa-spiro[2,5]octane-2-carboxylic acid methyl ester
1012336-01-4

2-chloro-6-cyano-6-(4-methoxy-dibenzofuran-1-yl)-1-oxa-spiro[2,5]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium methylate In tetrahydrofuran at 0 - 20℃; for 1h;95%
(1R,2S)-2-amino-3-fluoro-1-(4-methylsulphonylphenyl)-1-propanol hydrochloride

(1R,2S)-2-amino-3-fluoro-1-(4-methylsulphonylphenyl)-1-propanol hydrochloride

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

Florfenicol
73231-34-2

Florfenicol

Conditions
ConditionsYield
With triethylamine In methanol Heating;95%
With sodium hydrogencarbonate In methanol at 50℃; for 16h;5.6 g
With triethylamine In methanol at 50℃; for 10h;7.1 g
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(2S,3R)-methyl 2-[(tert-butoxycarbonyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propanoate

(2S,3R)-methyl 2-[(tert-butoxycarbonyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propanoate

methyl 2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate

methyl 2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoate

Conditions
ConditionsYield
Stage #1: (2S,3R)-methyl 2-[(tert-butoxycarbonyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propanoate With hydrogenchloride In ethyl acetate at 0 - 20℃; for 2h;
Stage #2: dichloroacetic acid methyl ester With sodium hydrogencarbonate In water at 0℃; for 1h;
95%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

nitrobenzene
98-95-3

nitrobenzene

methyl chloro-(4-nitrophenyl)-acetate
148582-35-8

methyl chloro-(4-nitrophenyl)-acetate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at -15℃; for 4h;94%
With potassium tert-butylate In N,N-dimethyl-formamide at -15℃;80%
dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

2,2:4,5-di-O-isopropylidene-D-arabinose
13039-93-5

2,2:4,5-di-O-isopropylidene-D-arabinose

(S)-2-Chloro-3-((4R,5S,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-oxirane-2-carboxylic acid methyl ester

(S)-2-Chloro-3-((4R,5S,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-oxirane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With potassium methanolate In methanol; diethyl ether at 0℃; Darzens reaction;94%
(S)-(+)-N-(5-phenylpentylidene)-p-toluenesulfinamide

(S)-(+)-N-(5-phenylpentylidene)-p-toluenesulfinamide

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(Ss,3S)-(+)-methyl N-(p-toluenesulfinyl)-2,2-dichloro-3-amino-7-phenylheptanoate

(Ss,3S)-(+)-methyl N-(p-toluenesulfinyl)-2,2-dichloro-3-amino-7-phenylheptanoate

Conditions
ConditionsYield
Stage #1: dichloroacetic acid methyl ester With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: (S)-(+)-N-(5-phenylpentylidene)-p-toluenesulfinamide In tetrahydrofuran at -78℃; for 0.166667h; Further stages.;
94%
(S)-(+)-N-(i-propylidene)-p-toluenesulfinamide

(S)-(+)-N-(i-propylidene)-p-toluenesulfinamide

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

(Ss,3S)-(+)-methyl N-(p-toluenesulfinyl)-2,2-dichloro-3-amino-4-methylpentanoate

(Ss,3S)-(+)-methyl N-(p-toluenesulfinyl)-2,2-dichloro-3-amino-4-methylpentanoate

Conditions
ConditionsYield
Stage #1: dichloroacetic acid methyl ester With lithium hexamethyldisilazane In tetrahydrofuran at -78℃;
Stage #2: (S)-(+)-N-(i-propylidene)-p-toluenesulfinamide In tetrahydrofuran at -78℃; Further stages.;
94%
1H-imidazole
288-32-4

1H-imidazole

dichloroacetic acid methyl ester
116-54-1

dichloroacetic acid methyl ester

C9H10N4O2

C9H10N4O2

Conditions
ConditionsYield
With tetrabutyl-ammonium chloride; potassium carbonate In tetrahydrofuran Reagent/catalyst; Solvent; Reflux;93.85%

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