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Jiangsu Willing Bio-Tech Co ltd

Our advantages: 1. Good quality: Our factory has strict quality control system and passed USA FDA inspection in 2017 . 2. Competitive price : We are the factory located in Huai’an city,make sure we can support the best price. 3. Fast

Fipronil\high quality\competitive price

Cas:120068-37-3

Min.Order:100 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

Insecticide Fipronil 95-98%TC 80%WDG 25%SC

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $114.0 / 128.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

Specifications Classification: Insecticide CAS No.: 120068-37-3 Other Names: Fipronil MF: C12H4Cl2F6N4OS EINECS No.: 424-610-5

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

97% up by HPLC Fipronil 120068-37-3

Cas:120068-37-3

Min.Order:2 Kilogram

FOB Price: $55.0 / 200.0

Type:Trading Company

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Fipronil Cas120068-37-3 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Light yellow to offwhite powder Storage:Store in 0-6°C Package:25kg/drum App

High quality Fipronil Cas120068-37-3 with best price

Cas:120068-37-3

Min.Order:25 Kilogram

FOB Price: $110.0 / 120.0

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

Top Quality and best price Fipronil 99% CAS. 120068-37-3

Cas:120068-37-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Insecticide 99% Fipronil powder Cas:120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $79.0 / 98.0

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Product Information Product Name: Fipronil, 120068-37-3, Insecticide Chemical Name: Fipronil Molecular Formula: C12H4Cl2F6N4OS Molecular Weight: 437.15 Specification Appearance Shallow yellow or whi

Fipronil 120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Think Chemical Co. Ltd

Fipronil 99%min CAS No.:120068-37-3 Name Fipronil Synonyms 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Molecular Structure Molecular Formula C12H4Cl2F6N4OS

Fipronil 99%min CAS No.:120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

huge stock TC Insecticide Fipronil 120068-37-3 GLP Manufacturer

Cas:120068-37-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Fipronil

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Fipronil

Cas:120068-37-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Fipronil Manufacturer/High quality/Best price/In stock

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Fipronil

Cas:120068-37-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name: fipronil CAS no. : 120068-37-3 Molecular formula: C12H4Cl2F6N4OS Molecular weight:437.1478 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerab

fipronil /CAS :120068-37-3/raw material/high-quality

Cas:120068-37-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

different specifications, 98.0%, 80.0% 50.0% Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsun

TIANFU-CHEM Fipronil 120068-37-3

Cas:120068-37-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturing

Fipronil CAS No.:120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 120068-37-3 with competitive price

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Fipronil Synonyms: 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile CAS:120068-37-3 MF: C12H4Cl2F6N4OS Appearance: white powder Storage:Store in cool and dry place, away from sun li

Fipronil CAS:120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High qu

97% Organic Insecticide CAS 120068-37-3 Fipronil

Cas:120068-37-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

High Purity CAS 120068-37-3 Insecticide Fipronil for Veterinary

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Fipronil 120068-37-3

Cas:120068-37-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Veterinary grade Fipronil Powder Pesticide Fipronil Insecticide Fipronil raw powder

Cas:120068-37-3

Min.Order:10 Gram

FOB Price: $3.5

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Fipronil CAS: 120068-37-3 MF: C12H4Cl2F6N4OS MW: 437.15 EINECS: 424-610-5 Mol File: 120068-37-3.mol Fipronil Structure Fipronil Chemical Properties Melting point 200-201°C Boiling point 510.1±50.0

C12H4Cl2F6N4OS

Cas:120068-37-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Fipronil Organochlorine insecticide

Cas:120068-37-3

Min.Order:1 Kilogram

FOB Price: $15.0 / 25.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Fipronil CAS: 120068-37-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Fipronil CAS: 120068-37-3

Cas:120068-37-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Fipronil

Cas:120068-37-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Kemi-Works Chemical Co., Ltd

1.Product name: Fipronil 2.CAS No.120068-37-3 3.MF:C12H4Cl2F6N4OS 4.Assay: 95% min. or 98.0% min. or 99.0% min 5.Appearance:White crysta Appearance:white crystal Storage:Store in dry and cool place with good seal Package:1KG/ foil bag, 25kg/fib

Fipronil

Cas:120068-37-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Agrochemical insecticide Fipronil CAS NO.120068-37-3 CAS NO.120068-37-3

Cas:120068-37-3

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Synthetic route

trifluoromethylsulfinyl chloride
20621-29-8

trifluoromethylsulfinyl chloride

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
120068-79-3

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
With dimethylamine p-toluenesulfonate for 10h; Heating;99%
With dimethylamine p-toluenesulfonate at 50℃; for 8h;92%
With benzyltrimethylammonium chloride In 1,2-dichloro-ethane at 35℃; for 2h; Temperature; Industrial scale;90.3%
5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile
120067-83-6

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Stage #1: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile With dichloro-acetic acid; sulfuric acid at 15℃; for 0.5h;
Stage #2: With dihydrogen peroxide In water at 15℃; Product distribution / selectivity;
98%
With caro's acid In dichloromethane at 0 - 5℃; Reagent/catalyst; Industrial scale;97.9%
With dihydrogen peroxide In dichloro-acetic acid; water; trichloroacetic acid at 20℃; for 2h; Product distribution / selectivity;95%
5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile
120067-83-6

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile

A

fipronil
120068-37-3

fipronil

B

fipronil sulfone
120068-36-2

fipronil sulfone

Conditions
ConditionsYield
With dihydrogen peroxide; trifluoroacetic acid In dichloromethane at 10 - 12℃; for 3h;A 96%
B n/a
Stage #1: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile With trifluoroacetic acid for 0.25h;
Stage #2: With Oxone at -15℃; Product distribution / selectivity;
A 55.4%
B n/a
Stage #1: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile With trifluoroacetic acid for 0.25h; Industry scale;
Stage #2: With Oxone at -15℃; Product distribution / selectivity; Industry scale;
trifluoromethylsulfinyl chloride
20621-29-8

trifluoromethylsulfinyl chloride

dimethylamine p-toluenesulfonate
2840-22-4

dimethylamine p-toluenesulfonate

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
120068-79-3

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
In water; toluene88%
Langlois reagent
2926-29-6

Langlois reagent

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
120068-79-3

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
With trichlorophosphate; dimethylamine p-toluenesulfonate at 40℃; for 14h; Product distribution / selectivity;80.2%
With thionyl chloride; dimethylamine p-toluenesulfonate at 40℃; for 10h; Product distribution / selectivity;74.8%
Stage #1: Langlois reagent With thionyl chloride; dimethylamine p-toluenesulfonate In toluene at 0 - 5℃; for 0.5h;
Stage #2: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole In toluene at 5 - 50℃; for 6.08333h; Product distribution / selectivity;
73%
potassium triflinate
41804-89-1

potassium triflinate

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
120068-79-3

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Stage #1: potassium triflinate With thionyl chloride; triethylamine hydrochloride In toluene at 0 - 5℃; for 0.5 - 0.833333h;
Stage #2: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole In toluene at 5 - 35℃; for 11.75h; Product distribution / selectivity;
66%
Stage #1: potassium triflinate With thionyl chloride; pyridine hydrochloride In toluene at 0 - 5℃; for 0.833333h;
Stage #2: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole In toluene at 5 - 35℃; for 11.75h; Product distribution / selectivity;
Stage #1: potassium triflinate With thionyl chloride; trimethylamine hydrochloride In toluene at 0 - 5℃; for 0.833333h;
Stage #2: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole In toluene at 5 - 35℃; for 11.75h; Product distribution / selectivity;
5-amino-4-trifluoromethylsulfinyl-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-thiocarbamoylpyrazole
208652-17-9

5-amino-4-trifluoromethylsulfinyl-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-thiocarbamoylpyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
With hydrogenchloride In water; acetonitrile Product distribution / selectivity;
In water; acetonitrile Product distribution / selectivity; fluorescent light;
In water; acetonitrile at 65℃; Product distribution / selectivity;
sulfur dioxide
7446-09-5

sulfur dioxide

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile
120067-83-6

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
With dihydrogen peroxide; boric acid; trifluoroacetic acid In chlorobenzene
5-amino-3-bromo-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylthiopyrazole
120067-94-9

5-amino-3-bromo-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylthiopyrazole

A

5-amino-3-bromo-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulphinylpyrazole
120068-43-1

5-amino-3-bromo-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulphinylpyrazole

B

fipronil
120068-37-3

fipronil

trifluoromethanesulfinic acid
34642-42-7

trifluoromethanesulfinic acid

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole
120068-79-3

5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Stage #1: trifluoromethanesulfinic acid With thionyl chloride; triethylamine In toluene at 0 - 5℃; for 0.5h;
Stage #2: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole; triethylamine hydrochloride In toluene at 50℃; for 6h; Product distribution / selectivity;
With thionyl chloride; N,N-dimethylisopropyl amine; potassium chloride; isopropyl-dimethyl-amine; hydrochloride In ethylbenzene at 0 - 35℃; for 11.75h; Inert atmosphere;
2,6-dichloro-4-(trifluoromethyl)aniline
24279-39-8

2,6-dichloro-4-(trifluoromethyl)aniline

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: nitrosylsulfuric acid; acetic acid / 30 - 55 °C
1.2: 0 - 15 °C
2.1: dichloromethane
3.1: boric acid; trichloroacetic acid; dihydrogen peroxide / chlorobenzene; water / 20 h / 15 - 20 °C
View Scheme
1,2-dichloro-4-(trifluoromethyl)benzene
328-84-7

1,2-dichloro-4-(trifluoromethyl)benzene

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: dimethylsulfone; potassium fluoride; ammonia / 6 h / 30 - 235 °C / 18751.9 - 19502 Torr / Autoclave
2.1: sulfuryl dichloride; 1-methyl-pyrrolidin-2-one / 1-methyl-pyrrolidin-2-one; chlorobenzene / 8 h / 55 - 60 °C
3.1: nitrosylsulfuric acid; acetic acid / 30 - 55 °C
3.2: 0 - 15 °C
4.1: dichloromethane
5.1: boric acid; trichloroacetic acid; dihydrogen peroxide / chlorobenzene; water / 20 h / 15 - 20 °C
View Scheme
Multi-step reaction with 5 steps
1.1: 1-methyl-pyrrolidin-2-one; potassium fluoride; ammonia / 10 h / 245 - 250 °C / 22502.3 - 30003 Torr / Autoclave
2.1: sulfuryl dichloride; 1-methyl-pyrrolidin-2-one / 1-methyl-pyrrolidin-2-one; chlorobenzene / 8 h / 55 - 60 °C
3.1: nitrosylsulfuric acid; acetic acid / 30 - 55 °C
3.2: 0 - 15 °C
4.1: dichloromethane
5.1: boric acid; trichloroacetic acid; dihydrogen peroxide / chlorobenzene; water / 20 h / 15 - 20 °C
View Scheme
2-chloro-4-(trifluoromethyl)aniline
39885-50-2

2-chloro-4-(trifluoromethyl)aniline

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sulfuryl dichloride; 1-methyl-pyrrolidin-2-one / 1-methyl-pyrrolidin-2-one; chlorobenzene / 8 h / 55 - 60 °C
2.1: nitrosylsulfuric acid; acetic acid / 30 - 55 °C
2.2: 0 - 15 °C
3.1: dichloromethane
4.1: boric acid; trichloroacetic acid; dihydrogen peroxide / chlorobenzene; water / 20 h / 15 - 20 °C
View Scheme
dihydrogen peroxide
7722-84-1

dihydrogen peroxide

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile
120067-83-6

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile

fipronil
120068-37-3

fipronil

Conditions
ConditionsYield
With hydrogenchloride; sodium tungstate In water; 1,2-dichloro-ethane at 2 - 8℃; Large scale;
orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

fipronil
120068-37-3

fipronil

3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-5-ethoxymethylideneamino-4-trifluoromethylsulfinylpyrazole

3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-5-ethoxymethylideneamino-4-trifluoromethylsulfinylpyrazole

Conditions
ConditionsYield
99%
99%
4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-nitro-benzylidene)amino)-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-nitro-benzylidene)amino)-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;98.9%
n-Butyl chloride
109-69-3

n-Butyl chloride

fipronil
120068-37-3

fipronil

N-5-butylamino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazole

N-5-butylamino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 80℃; for 8h; Sonication;96.7%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-(4-fluorobenzylideneamino)-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-(4-fluorobenzylideneamino)-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;96.5%
With toluene-4-sulfonic acid In chlorobenzene for 1h; Molecular sieve; Microwave irradiation; Sealed tube;73%
2-Nitrobenzenesulfonyl chloride
1694-92-4

2-Nitrobenzenesulfonyl chloride

fipronil
120068-37-3

fipronil

C18H7Cl2F6N5O5S2
1225373-70-5

C18H7Cl2F6N5O5S2

Conditions
ConditionsYield
With sodium hydride In ethyl acetate at 0 - 20℃;96%
With sodium hydride In ethyl acetate at 2 - 20℃; for 4h;79.3%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

fipronil
120068-37-3

fipronil

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)butyl

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)butyl

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 3h; Sonication; Microwave irradiation; Heating;95.2%
1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-(4-bromophenylsulfonylamino)-1H-pyrazole-3-carbonitrile
1014394-95-6

1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-(4-bromophenylsulfonylamino)-1H-pyrazole-3-carbonitrile

fipronil
120068-37-3

fipronil

C18H7BrCl2F6N4O3S2
1225373-68-1

C18H7BrCl2F6N4O3S2

Conditions
ConditionsYield
With sodium hydride In ethyl acetate at 0 - 20℃;95%
benzaldehyde
100-52-7

benzaldehyde

fipronil
120068-37-3

fipronil

5-(benzylideneamino)-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile

5-(benzylideneamino)-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;94.8%
With toluene-4-sulfonic acid In toluene for 1h; Reagent/catalyst; Molecular sieve; Microwave irradiation; Sealed tube;84%
5-bromo-2-thiophenesulfonyl chloride
55854-46-1

5-bromo-2-thiophenesulfonyl chloride

fipronil
120068-37-3

fipronil

C16H5BrCl2F6N4O3S3

C16H5BrCl2F6N4O3S3

Conditions
ConditionsYield
With sodium hydride In ethyl acetate at 0 - 20℃;93%
1-bromo-butane
109-65-9

1-bromo-butane

fipronil
120068-37-3

fipronil

N-5-butylamino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazole

N-5-butylamino-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazole

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 3h; Time; Sonication; Microwave irradiation; Heating;92.6%
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 1h;92.6%
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-methylbenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-methylbenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;92.6%
3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((3-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((3-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;91.8%
ethyl bromoacetate
105-36-2

ethyl bromoacetate

fipronil
120068-37-3

fipronil

ethyl N-[3-cyano-1-[2,6-dichloro-4-(trifluoromethyl)-phenyl]-4-[(trifluoromethyl)-sulfinyl]-1H-pyrazol-5-yl]-aminoacetate
1430089-22-7

ethyl N-[3-cyano-1-[2,6-dichloro-4-(trifluoromethyl)-phenyl]-4-[(trifluoromethyl)-sulfinyl]-1H-pyrazol-5-yl]-aminoacetate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 3h; Cooling with ice;91%
1,4-diphenyl-but-2-ene-1,4-dione
4070-75-1

1,4-diphenyl-but-2-ene-1,4-dione

fipronil
120068-37-3

fipronil

C28H15ClF6N4O3S

C28H15ClF6N4O3S

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 50℃;91%
ethoxyacetyl chloride
14077-58-8

ethoxyacetyl chloride

triethylamine
121-44-8

triethylamine

fipronil
120068-37-3

fipronil

triethylamine salt of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-5-(ethoxyacetamido)pyrazole
379215-14-2

triethylamine salt of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-5-(ethoxyacetamido)pyrazole

Conditions
ConditionsYield
In tetrahydrofuran at 60℃; for 1.5h;90%
benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

fipronil
120068-37-3

fipronil

C18H8Cl2F6N4O3S2
1225373-74-9

C18H8Cl2F6N4O3S2

Conditions
ConditionsYield
With sodium hydride In ethyl acetate at 0 - 20℃;90%
fipronil
120068-37-3

fipronil

1,4-dimethyl but-2-enedioate
23055-10-9

1,4-dimethyl but-2-enedioate

C18H11ClF6N4O5S

C18H11ClF6N4O5S

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 50℃;90%
1,4-bibromocyclohexane
35076-92-7

1,4-bibromocyclohexane

fipronil
120068-37-3

fipronil

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5-ylamino)cyclohexyl

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5-ylamino)cyclohexyl

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 3h; Sonication; Microwave irradiation; Heating;89.5%
1,4-bis(bromomethyl)benzene
623-24-5

1,4-bis(bromomethyl)benzene

fipronil
120068-37-3

fipronil

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)benzyl

N-bis(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)benzyl

Conditions
ConditionsYield
With potassium hydroxide In toluene at 20℃; for 3h; Sonication; Microwave irradiation; Heating;89.3%
ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((2-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((2-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;88.7%
p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

fipronil
120068-37-3

fipronil

C19H10Cl2F6N4O3S2
1225373-72-7

C19H10Cl2F6N4O3S2

Conditions
ConditionsYield
With sodium hydride In ethyl acetate at 0 - 20℃;88%
C7H12O7S

C7H12O7S

fipronil
120068-37-3

fipronil

C18H11ClF6N4O5S

C18H11ClF6N4O5S

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 50℃;88%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

fipronil
120068-37-3

fipronil

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 200℃; for 3h; Temperature; Time; Molecular sieve; High pressure; Sonication; Autoclave; Sealed tube;87.4%
With toluene-4-sulfonic acid In 1,3,5-trimethyl-benzene for 1h; Molecular sieve; Microwave irradiation; Sealed tube;78%
α,α',α''-trichloromesitylene
17299-97-7

α,α',α''-trichloromesitylene

fipronil
120068-37-3

fipronil

N-1,3,5-tri(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)benzyl

N-1,3,5-tri(1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-1H-pyrazol-5ylamino)benzyl

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 3h; Sonication; Microwave irradiation; Heating;87.2%
ethoxyacetyl chloride
14077-58-8

ethoxyacetyl chloride

fipronil
120068-37-3

fipronil

potassium salt of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-5-(ethoxyacetamido)pyrazole

potassium salt of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinyl-5-(ethoxyacetamido)pyrazole

Conditions
ConditionsYield
With potassium hydroxide In acetonitrile at -5℃; for 4h;87%
Stage #1: ethoxyacetyl chloride; fipronil With triethylamine In tetrahydrofuran at 30℃; for 5h;
Stage #2: With hydrogenchloride In tetrahydrofuran; dichloromethane; water pH=2;
Stage #3: With potassium carbonate In tetrahydrofuran; dichloromethane; water
65%
Dimethyl oxalate
553-90-2

Dimethyl oxalate

fipronil
120068-37-3

fipronil

N,N'-bis[3-cyano-4-trifluoromethylsulfinyl-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazolyl]ethanediamide

N,N'-bis[3-cyano-4-trifluoromethylsulfinyl-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazolyl]ethanediamide

Conditions
ConditionsYield
With sodium ethanolate In toluene at 120℃; for 12h; Temperature; Time;86.5%
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