Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:24915-95-5
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inquiryAssay: 98% up by GC; Stable supply with over 50Mt annually; Appearance:Colorless to light yellow liquid Storage:room temprature Package:25kg/drum Application:Intermediate in organic synthesis Port:Beijing/Shanghai/Shenzhen/Hangzhou
Cas:24915-95-5
Min.Order:1 Kilogram
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inquiryhe company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:24915-95-5
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inquiryDayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica
Cas:24915-95-5
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:24915-95-5
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:24915-95-5
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inquiryEthyl (R)-3-hydroxybutyrate Basic information Product Name: Ethyl (R)-3-hydroxybutyrate Synonyms: (R)-(-)-ETHYL 3-HYDROXYBUTANOATE;(R)-(-)-ETHYL 3-HYDROXYBUTYRATE;(R)-(-)-3-HYDROXYBUTYRI
Cas:24915-95-5
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:24915-95-5
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
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inquiryAppearance:clear colorless liquid Storage:2-8°C Package:25kg/Barrel Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in China
Cas:24915-95-5
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:24915-95-5
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inquiryEthyl (R)-3-hydroxybutyrate CAS:24915-95-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ
Cas:24915-95-5
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:24915-95-5
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:24915-95-5
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:24915-95-5
Min.Order:4 Kilogram
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inquirylower price and high quality Appearance:White Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical Intermediate Transportation:shipping,land,a
Cas:24915-95-5
Min.Order:1 Gram
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:24915-95-5
Min.Order:10 Gram
FOB Price: $100.0
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:24915-95-5
Min.Order:1 Kilogram
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inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:24915-95-5
Min.Order:1 Milligram
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inquiryEthyl (R)-3-hydroxybutyrate Basic information Product Name: Ethyl (R)-3-hydroxybutyrate Synonyms: (R)-(-)-ETHYL 3-HYDROXYBUTANOATE;(R)-(-)-ETHYL 3-HYDROXYBUTYRATE;(R)-(-)-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-3-HYDROXYBUTYRIC ACID ETHYL ESTER;
Cas:24915-95-5
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:24915-95-5
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:24915-95-5
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:24915-95-5
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inquiryProduct name Ethyl (R)-3-hydroxybutyrate Content ≥98% CAS NO. 24915-95-5 Package Structure Formula Appearance:Detai
Cas:24915-95-5
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryLocated in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h
Cas:24915-95-5
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inquiryHigh quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
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inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
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inquiryethyl acetoacetate
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With (S)-4,12-bis(diphenylphosphino)-<2.2>paracyclophane-Ru(II)bis(trifluoroacetate); hydrogen; tetra-(n-butyl)ammonium iodide In methanol; water at -5℃; under 2585.7 Torr; for 18h; | 100% |
With hydrogen; Ru(R-Xyl-P-Phos)(C6H6)Cl2 In ethanol; dichloromethane at 70℃; under 10343 Torr; for 1h; | 100% |
With [(+)-N,N'-Me2-3,3'-(Ph2P)2-1,1'-biindole]RuCl2; hydrogen In methanol; water at 45℃; under 79805.4 Torr; for 0.5h; | 100% |
ethyl 3-hydroxybutyrate
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase at 30℃; for 24h; pH=7.5; aq. buffer; Resolution of racemate; Enzymatic reaction; optical yield given as %ee; enantiospecific reaction; | 99% |
(R)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sodium perborate In tetrahydrofuran; water at 20℃; | 94% |
With sodium peroxoborate tetrahydrate In tetrahydrofuran; water at 20℃; for 3h; | 84% |
With sodium perborate tetrahydrate In tetrahydrofuran; water Inert atmosphere; |
ethyl acetoacetate
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
With citrate-phosphate-borate buffer for 24h; Ambient temperature; baker's yeast immobilized in calcium alginate; Title compound not separated from byproducts; | A n/a B 85% |
With Convolvulus sepium for 120h; pH=5.8; aq. phosphate buffer; optical yield given as %ee; | A n/a B 70% |
yeast Conversion of starting material; Enzymatic reaction; | A n/a B 26% |
ethanol
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (3R)-hydroxyvalerate
Conditions | Yield |
---|---|
With sulfuric acid In 1,2-dichloro-ethane for 48h; Heating; | A 84% B 59% |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In ethanol Heating; | 83% |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In 1,2-dichloro-ethane Heating; | 82% |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In 1,2-dichloro-ethane for 75h; Reflux; | 81% |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In ethanol; 1,2-dichloro-ethane for 37h; Heating; Irradiation; | 80% |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In 1,2-dichloro-ethane for 96h; Heating; | 71% |
Conditions | Yield |
---|---|
With sulfuric acid at 20℃; | 66% |
With sulfuric acid |
ethyl 4,4,4-trifluoroacetoacetate
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate
C
ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate
Conditions | Yield |
---|---|
With Fala baker' yeast; allyl alcohol Microbiological reaction; | A 62% B n/a C n/a |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid In 1,2-dichloro-ethane for 48h; | 60% |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With trimethyltin(IV) hydroxide In 1,2-dichloro-ethane at 60℃; for 10h; Inert atmosphere; chemoselective reaction; | 58% |
ethyl acetoacetate
A
Ethyl (R)-3-hydroxybutanoate
B
3,3-bismethoxybutyric acid methyl ester
Conditions | Yield |
---|---|
With <(+)-2,2'-bis(diphenylphosphino)-4,4',6,6'-tetramethyl-3,3'-bibenzothiophene>RuCl2; hydrogen In methanol at 70℃; under 73550.8 Torr; for 2h; Yield given; | A n/a B 5% |
Conditions | Yield |
---|---|
With sulfuric acid |
ethyl 3-hydroxybutyrate
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
Yield given. Yields of byproduct given. Title compound not separated from byproducts; | |
With pentyl cage-coated capillary column Resolution of racemate; | |
With homochiral metal-organic cage [Zn3(deprotonated [3+3] macrocyclic Schiff base of trans-1,2-diaminocyclohexane and 4-tert-butyl-2,6-diformylphenol)2] coated capillary column In dichloromethane at 118℃; Resolution of racemate; enantioselective reaction; |
ethyl acetoacetate
A
(S)-3-Hydroxybutanoic Acid
B
(R)-3-hydroxybutyric acid
C
Ethyl (R)-3-hydroxybutanoate
D
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
With Halobacterium halobium; pepton; potassium chloride; water; sodium citrate; magnesium sulfate; sodium chloride at 40℃; for 120h; Irradiation; Yields of byproduct given. Title compound not separated from byproducts; | |
With Halobacterium halobium; pepton; potassium chloride; sodium citrate; magnesium sulfate; sodium chloride In water at 40℃; for 120h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
ethyl 3-nitro-oxy-butanoate
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In methanol Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
ethyl (S)-3-hydroxybutyrate
N,N-dimethyl-formamide
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid 2.) MeOH, 1 h, room temperature; Yield given; |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sodium tetrahydroborate; hydrogen; nickel dichloride for 16h; Ambient temperature; Yield given; |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid |
ethanol
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With sulfuric acid 1.) 1,2-dichloroethane, reflux, 2 h; 2.) reflux, 48 h; Yield given. Multistep reaction; |
ethyl 4,4,4-trifluoroacetoacetate
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate
C
ethyl acetoacetate
D
ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate
Conditions | Yield |
---|---|
With Fala baker' yeast; allyl alcohol |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With hydrogenchloride; ethanol In 1,2-dichloro-ethane for 12h; Heating; | 0.93 g |
ethanol
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (3R)-hydroxyvalerate
Conditions | Yield |
---|---|
Stage #1: poly[(R)-hydroxybutyrate] BIOPOL D300G In dichloromethane at 83℃; for 2h; Stage #2: ethanol With sulfuric acid In dichloromethane for 71h; Heating; Title compound not separated from byproducts; |
trans-Crotonaldehyde
ethanol
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
Stage #1: trans-Crotonaldehyde; ethanol With dihydrogen peroxide In chloroform at -20℃; for 16h; Stage #2: With N-ethyl-N,N-diisopropylamine In chloroform at 30℃; for 15h; Further stages. Title compound not separated from byproducts.; |
ethyl (S)-3-tosyloxy-butanoate
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90 percent / (n-Bu4)N(1+)*NO3(1-) / benzene / 6 h / Heating 2: H2 / Pd/C / methanol View Scheme |
acetylacetone
A
Ethyl (R)-3-hydroxybutanoate
B
ethyl (S)-3-hydroxybutyrate
Conditions | Yield |
---|---|
With D-glucose In phosphate buffer at 30℃; for 12h; pH=7; Title compound not separated from byproducts.; |
Ethyl (R)-3-hydroxybutanoate
tert-butyldimethylsilyl chloride
ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 0℃; | 100% |
With 1H-imidazole In dichloromethane | 100% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; | 100% |
Ethyl (R)-3-hydroxybutanoate
ethyl vinyl ether
Conditions | Yield |
---|---|
trifluoroacetic acid | 100% |
3,4-dihydro-2H-pyran
Ethyl (R)-3-hydroxybutanoate
(3R,2'RS)-3-<(Tetrahydropyran-2'-yl)oxy>buttersaeure-ethylester
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In dichloromethane at 0℃; for 0.25h; | 100% |
With toluene-4-sulfonic acid In diethyl ether | 100% |
With pyridinium p-toluenesulfonate In dichloromethane at 0 - 20℃; for 24h; Inert atmosphere; Schlenk technique; | 91% |
With toluene-4-sulfonic acid |
Ethyl (R)-3-hydroxybutanoate
tert-butylchlorodiphenylsilane
(R)-3-(tert-butyl-diphenyl-silanyloxy)-butyraldehyde
Conditions | Yield |
---|---|
Stage #1: Ethyl (R)-3-hydroxybutanoate; tert-butylchlorodiphenylsilane With 1H-imidazole; dmap In dichloromethane Stage #2: With diisobutylaluminium hydride In dichloromethane at -78℃; Further stages.; | 100% |
Ethyl (R)-3-hydroxybutanoate
ethyl vinyl ether
ethyl-3-(1-ethoxyethoxy)-butanoate
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate In dichloromethane for 1h; Ambient temperature; | 99% |
Ethyl (R)-3-hydroxybutanoate
tert-butylchlorodiphenylsilane
ethyl (R)-3-(tert-butyldiphenylsilyloxy)butyrate
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide | 99% |
With 1H-imidazole; dmap In dichloromethane at 0 - 20℃; | 99% |
With 1H-imidazole In N,N-dimethyl-formamide for 72h; Ambient temperature; | 96% |
With 1H-imidazole In N,N-dimethyl-formamide for 3h; Ambient temperature; | 95% |
With 1H-imidazole In dichloromethane at 0 - 20℃; for 6h; | 80% |
Ethyl (R)-3-hydroxybutanoate
methanesulfonyl chloride
(-)-(R)-Ethyl 3-(mesyloxy)butanoate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere; | 99% |
With triethylamine In dichloromethane at 0℃; for 1h; | 97% |
With triethylamine In dichloromethane | 75% |
Conditions | Yield |
---|---|
scandium tris(trifluoromethanesulfonate) at 64℃; for 10h; | 98% |
(EtO)3TiO(CH2)2OTi(OEt)3 autoclave, 1.) 160 deg C, 17 bar, 2 h; 2.) 115 deg C, 3.5 bar, 27 h; | 82% |
Ethyl (R)-3-hydroxybutanoate
triethylsilyl chloride
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 20℃; for 18h; | 96% |
With 1H-imidazole In dichloromethane |
Ethyl (R)-3-hydroxybutanoate
p-toluenesulfonyl chloride
(-)-(R)-Ethyl 3-<(p-tolylsulfonyl)oxy>butanoate
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 12h; | 95% |
With pyridine In chloroform at 0℃; for 12h; | 71% |
With pyridine at 0℃; for 24h; | 22.1 g |
Ethyl (R)-3-hydroxybutanoate
t-butyldimethylsiyl triflate
ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate
Conditions | Yield |
---|---|
With 2,6-dimethylpyridine In dichloromethane at 0 - 20℃; for 2.5h; | 95% |
With pyridine In dichloromethane at 0 - 20℃; | 62% |
With pyridine Etherification; |
Ethyl (R)-3-hydroxybutanoate
chloromethyl methyl ether
(R)-ethyl 3-(methoxymethoxy)butanoate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; | 95% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Etherification; | 86% |
With N-ethyl-N,N-diisopropylamine In dichloromethane | 75% |
Ethyl (R)-3-hydroxybutanoate
methyl 3'-(cyanocarbonyl)-2,2'-binaphthalene-3-carboxylate
Conditions | Yield |
---|---|
With dmap In acetonitrile at 20℃; for 2h; | 95% |
Ethyl (R)-3-hydroxybutanoate
methyl iodide
ethyl anti-(2R,3R)-2-methyl-3-hydroxybutanoate
Conditions | Yield |
---|---|
Stage #1: Ethyl (R)-3-hydroxybutanoate With n-butyllithium; diisopropylamine In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - -40℃; for 0.333333h; Frater-Seebach alkylation; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - 0℃; Frater-Seebach alkylation; Inert atmosphere; enantioselective reaction; | 94% |
Stage #1: Ethyl (R)-3-hydroxybutanoate With lithium diisopropyl amide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - -40℃; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - 0℃; for 2h; Inert atmosphere; | 92% |
With lithium diisopropyl amide In tetrahydrofuran at -78℃; | 84% |
Ethyl (R)-3-hydroxybutanoate
(R)-3-hydroxybutyric acid
Conditions | Yield |
---|---|
With potassium hydroxide at 0℃; for 24h; | 93% |
With sodium hydroxide In water at 10℃; for 6h; | 85% |
With potassium hydroxide for 12h; Ambient temperature; |
(η5-C5H4CH3)3Pr
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
In toluene N2-atmosphere; equimolar amts., -70°C; elem. anal.; | 93% |
Ethyl (R)-3-hydroxybutanoate
(2-trimethylethylsilylethoxy)methyl chloride
Ethyl (3R)-3-{[2-(trimethylsilyl)ethoxy]methoxy}butanoate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h; | 93% |
3,4-dihydro-2H-pyran
Ethyl (R)-3-hydroxybutanoate
ethyl (R)-β-tetrahydropyranyloxybutyrate
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate In dichloromethane for 3h; Ambient temperature; | 92.5% |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol at 90℃; for 16h; Inert atmosphere; | 92% |
With hydrazine hydrate In ethanol at 90℃; for 16h; | 92% |
With hydrazine hydrate In ethanol; water Reflux; | 1.95 g |
Ethyl (R)-3-hydroxybutanoate
potassium (R)-3-hydroxybutyrate
Conditions | Yield |
---|---|
With potassium hydroxide In water at 10℃; for 5h; | 88.2% |
Ethyl (R)-3-hydroxybutanoate
benzylamine
(R)-N-benzyl-3-hydroxybutanamide
Conditions | Yield |
---|---|
Stage #1: benzylamine With trimethylaluminum In toluene at -5 - 20℃; Stage #2: Ethyl (R)-3-hydroxybutanoate In toluene at -5 - 20℃; for 15.5h; | 88% |
Ethyl (R)-3-hydroxybutanoate
O-(4-methoxybenzyl)-trichloroacetimidate
(R)-3-(4-Methoxy-benzyloxy)-butyric acid ethyl ester
Conditions | Yield |
---|---|
With (1S)-10-camphorsulfonic acid In dichloromethane for 25h; Ambient temperature; | 86% |
Ethyl (R)-3-hydroxybutanoate
(R)-butane-1,3-diol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In diethyl ether for 1h; Ambient temperature; | 86% |
With lithium aluminium tetrahydride In diethyl ether at 0℃; for 0.5h; | 85.6% |
Stage #1: Ethyl (R)-3-hydroxybutanoate With lithium aluminium tetrahydride In diethyl ether at 0 - 20℃; for 3h; Inert atmosphere; Stage #2: With water In diethyl ether | 81% |
Ethyl (R)-3-hydroxybutanoate
(2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidate
C20H20Cl4O4
Conditions | Yield |
---|---|
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 20℃; for 1h; | 85% |
Ethyl (R)-3-hydroxybutanoate
Conditions | Yield |
---|---|
Stage #1: Ethyl (R)-3-hydroxybutanoate With sodium hydroxide In water at 10℃; for 5h; Stage #2: With magnesium hydroxide In water for 10h; | 85% |
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