Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:33252-30-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:33252-30-1
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Product advantage: large capacity in China, stable quality,competitive price Appearance:white powder Storage:cool place, well sealed Package:20kg/drum Application:Intermediate Transportation:By sea,by air Port:Any po
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Min.Order:1 Kilogram
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Cas:33252-30-1
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:33252-30-1
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:33252-30-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:33252-30-1
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:33252-30-1
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Type:Trading Company
inquiryName: 2-Chloroisonicotinonitrile Synonyms: 2-Chloro-Isonicotinonitrile CAS:33252-30-1 MF: C7H5Cl2F Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Pharmaceutical Intermediate
Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:33252-30-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry2-Chloro-4-cyanopyridine CAS:33252-30-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:33252-30-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se
Cas:33252-30-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s
Cas:33252-30-1
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:33252-30-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:33252-30-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:33252-30-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryadvantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packag
Cas:33252-30-1
Min.Order:1 Gram
Negotiable
Type:Other
inquiryWhy Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:33252-30-1
Min.Order:100 Gram
Negotiable
Type:Other
inquiryMassive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:33252-30-1
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:33252-30-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:White to off-white solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Intermediates T
Product name: 2-Chloro-4-Cyanopyridine CAS No.: 33252-30-1 Molecule Formula:C7H5Cl2F Molecule Weight:179.02 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard
Cas:33252-30-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryProduct Name: 2-Chloro-4-cyanopyridine Synonyms: BUTTPARK 43\57-01;4-CYANO-2-CHLORO PYRIDINE;2-CHLORO-4-CYANOPYRIDINE;2-CHLORO-4-PYRIDINECARBONITRILE;2-CHLOROPYRIDINE-4-CARBONITRILE;2-CHLOROISONICOTINONITRILE;2-CHLORO-4-CYANOPYRIDINE 99+%;2-CHL
Cas:33252-30-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:33252-30-1
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With ammonium formate; silica gel; zinc In methanol at 20℃; for 0.166667h; chemoselective reaction; | 89% |
4-cyanopyridine N-oxide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With trichlorophosphate at 100℃; for 24h; | 69% |
With triethylamine; trichlorophosphate In 1,2-dichloro-ethane for 4h; | 117.5 g |
4-Amino-2-chloropyridine
potassium cyanide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With sulfuric acid; copper(II) sulfate; sodium nitrite Diazotization.weitere Reagentien: Kupfer-Pulver, wss. Na2CO3; |
4-pyridine carboxamide 1-oxide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With phosphorus pentachloride; trichlorophosphate |
4-pyridine carboxamide 1-oxide
phosphorus pentachloride
trichlorophosphate
2-chloro-4-pyridinenitrile
2-chloropyridine-N-oxide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: concentrated sulfuric acid; nitric acid 2: acetic acid; iron-powder / anschliessend mit Zink-Pulver unter Zusatz von wenig wss. HgCl2 3: NaNO2; aqueous H2SO4; CuSO4 / Diazotization.weitere Reagentien: Kupfer-Pulver, wss. Na2CO3 View Scheme |
2-chloro-4-nitropyridine-N-oxide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: acetic acid; iron-powder / anschliessend mit Zink-Pulver unter Zusatz von wenig wss. HgCl2 2: NaNO2; aqueous H2SO4; CuSO4 / Diazotization.weitere Reagentien: Kupfer-Pulver, wss. Na2CO3 View Scheme |
isonicotinamide
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aqueous H2O2; acetic acid 2: POCl3; PCl5 View Scheme |
Conditions | Yield |
---|---|
With sodium hydroxide; trichlorophosphate In n-heptane |
4-cyanopyridine N-oxide
phosphorus pentachloride
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With trichlorophosphate | 8.4 g (24%) |
2-chloro-4-pyridinenitrile
tri-n-butyl(vinyl)tin
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In toluene for 2h; Reflux; Inert atmosphere; | 100% |
2-chloro-4-pyridinenitrile
4-trifluoromethylphenylboronic acid
2-[4-(trifluoromethyl)phenyl]pyridine 4-carbonitrile
Conditions | Yield |
---|---|
With [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); sodium carbonate In 1,4-dioxane; water at 120℃; for 0.333333h; Microwave irradiation; | 99% |
With caesium carbonate; palladium diacetate; XPhos In 1,4-dioxane at 100℃; for 4h; Sealed tube; | 78% |
Stage #1: 2-chloro-4-pyridinenitrile; 4-trifluoromethylphenylboronic acid With sodium hydrogencarbonate In 1,2-dimethoxyethane; water at 20℃; for 5h; Stage #2: With tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 100℃; | 47% |
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In 1,2-dimethoxyethane; water at 100℃; Inert atmosphere; | 47% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; Inert atmosphere; |
2-chloro-4-pyridinenitrile
2-chloro-4-pyridine carboxamide
Conditions | Yield |
---|---|
With manganese(IV) oxide; water In isopropyl alcohol at 60℃; under 5171.62 Torr; for 0.2h; | 98% |
With water at 110℃; for 20h; | 95% |
With ammonium hydroxide; cesiumhydroxide monohydrate at 100℃; for 1h; Schlenk technique; Sealed tube; | 89% |
With cesium hydroxide; water; dimethyl sulfoxide at 30℃; for 24h; Temperature; Schlenk technique; Green chemistry; | 88% |
Stage #1: 2-chloro-4-pyridinenitrile With caesium carbonate In 2-pyrrolidinon at 130℃; for 2h; Sealed vessel; Stage #2: With methanol In 2-pyrrolidinon; dichloromethane at 20℃; Filtering through Celite pad; | 72% |
2-chloro-4-pyridinenitrile
2-chloro-4-(1H-tetrazole-5-yl)pyridine
Conditions | Yield |
---|---|
With sodium azide; ammonium cerium (IV) nitrate In N,N-dimethyl-formamide at 110℃; for 6h; Inert atmosphere; Green chemistry; | 98% |
With sodium azide In N,N-dimethyl-formamide at 100℃; for 4h; Reagent/catalyst; Temperature; | 97% |
With sodium azide; gold In N,N-dimethyl-formamide at 80℃; for 1h; Reagent/catalyst; Inert atmosphere; | 96% |
2-chloro-4-pyridinenitrile
2-Amino-2-methyl-1-propanol
2-(2-chloropyridin-4-yl)-4,5-dihydro-4,4-dimethyloxazole
Conditions | Yield |
---|---|
With sodium carbonate In methanol at 80℃; for 15h; Inert atmosphere; Schlenk technique; | 98% |
2-chloro-4-pyridinenitrile
4-Chlorophenylboronic acid
2-(4-chlorophenyl)isonicotinonitrile
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; acetonitrile at 80℃; for 1h; Inert atmosphere; | 98% |
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; acetonitrile for 1h; Suzuki-Miyaura Coupling; Inert atmosphere; Reflux; | 96% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; Inert atmosphere; |
2-chloro-4-pyridinenitrile
trimethylsilylacetylene
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile at 60℃; for 3h; Inert atmosphere; | 98% |
2-chloro-4-pyridinenitrile
2-chloropyridine-4-carbothioamide
Conditions | Yield |
---|---|
With triethanolamine; hydrogen sulfide In ethanol | 97% |
With triethanolamine; ethanol; hydrogen sulfide |
2-chloro-4-pyridinenitrile
ethanolamine
Conditions | Yield |
---|---|
With sodium carbonate In methanol at 80℃; for 15h; Inert atmosphere; Schlenk technique; | 97% |
2-chloro-4-pyridinenitrile
4-trifluoromethoxyphenylboronic acid
2-[4-(trifluoromethoxy)phenyl]pyridine-4-carbonitrile
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In 1,2-dimethoxyethane; water at 100℃; for 12h; Inert atmosphere; | 96% |
With tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate In 1,2-dimethoxyethane; water at 100℃; for 12h; Inert atmosphere; | 96% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; Inert atmosphere; |
2-chloro-4-pyridinenitrile
meta-phenoxyphenol
Conditions | Yield |
---|---|
With caesium carbonate; N,N-dimethylethylenediamine at 20℃; for 16h; | 96% |
Conditions | Yield |
---|---|
Stage #1: phenol With caesium carbonate; N,N-dimethylethylenediamine at 20℃; for 0.5h; Stage #2: 2-chloro-4-pyridinenitrile at 80℃; for 2h; | 95% |
Stage #1: phenol With caesium carbonate In N,N-dimethyl acetamide at 20℃; for 0.5h; Stage #2: 2-chloro-4-pyridinenitrile In N,N-dimethyl acetamide at 80℃; for 20h; | 95% |
With caesium carbonate In 1-methyl-pyrrolidin-2-one at 80℃; for 16h; | 57.95% |
Stage #1: 2-chloro-4-pyridinenitrile; phenol With potassium carbonate In N,N-dimethyl-formamide at 120℃; Stage #2: With hydrogenchloride In water Cooling; |
2-chloro-4-pyridinenitrile
2-chloropyridine-4-carboximidamide hydrochloride
Conditions | Yield |
---|---|
With trimethylaluminum; ammonium chloride In toluene at 90℃; | 95% |
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 120℃; for 2h; Microwave irradiation; Inert atmosphere; | 95% |
2-chloro-4-pyridinenitrile
1,1-dimethylethyl (2S)-2-methyl-4-{[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-1-piperazinecarboxylate
1,1-dimethylethyl (2S)-4-{[3-(4-cyano-2-pyridinyl)phenyl]methyl}-2-methyl-1-piperazinecarboxylate
Conditions | Yield |
---|---|
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 140℃; for 0.5h; | 94% |
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 140℃; for 0.5h; Microwave irradiation; | 94% |
2-chloro-4-pyridinenitrile
methylamine
2-(methylamino)isonicotinonitrile
Conditions | Yield |
---|---|
In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 120℃; for 2h; Microwave irradiation; | 93% |
With sodium hydrogencarbonate In pyridine at 120℃; for 40h; | |
With sodium hydrogencarbonate In tetrahydrofuran; pyridine at 120℃; for 40h; | |
In tetrahydrofuran; water at 20℃; for 18h; | |
In tetrahydrofuran at 80℃; for 16h; Sealed tube; |
2-chloro-4-pyridinenitrile
methyl N-[6-(4-hydroxyphenyl)pyrimidin-4-yl]phenylalaninate
methyl N-(6-{4-[(4-cyanopyridin-2-yl)-oxy]phenyl}pyrimidin-4-yl)phenylalaninate
Conditions | Yield |
---|---|
With potassium carbonate In dimethyl sulfoxide at 60℃; | 93% |
Conditions | Yield |
---|---|
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 80℃; for 4h; Buchwald-Hartwig Coupling; Sealed tube; Inert atmosphere; | 93% |
2-chloro-4-pyridinenitrile
2-chloroisonicotinic acid,
Conditions | Yield |
---|---|
With 1-butyl-3-methylimidazolium hydrogen sulfate; water at 60 - 65℃; for 2.4h; Green chemistry; | 92% |
With hydrogenchloride |
2-chloro-4-pyridinenitrile
1-cyclopentylpiperazine
2-(4-cyclopentyl-piperazin-1-yl)-isonicotinonitrile
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 80℃; for 16h; | 92% |
2-chloro-4-pyridinenitrile
4-methylphenylboronic acid
2-(p-tolyl)isonicotinonitrile
Conditions | Yield |
---|---|
With sodium tetrachloropalladate(II); dicyclohexyl {2-sulfo-9-[3-(4-sulfophenyl)propyl]-9H-fluoren-9-yl}phosphonium hydrogen sulfate; potassium carbonate In water; butan-1-ol at 100℃; for 12h; Suzuki coupling; Inert atmosphere; | 92% |
Conditions | Yield |
---|---|
With sodium tetrachloropalladate(II); dicyclohexyl {2-sulfo-9-[3-(4-sulfophenyl)propyl]-9H-fluoren-9-yl}phosphonium hydrogen sulfate; potassium carbonate In water; butan-1-ol at 100℃; for 12h; Suzuki coupling; Inert atmosphere; | 91% |
2-chloro-4-pyridinenitrile
(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl In acetic acid methyl ester; toluene Solvent; Reflux; Inert atmosphere; | 91% |
Stage #1: 2-chloro-4-pyridinenitrile; (S)-N-((S)-1-(2-chlorophenyl)-2- ((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene Inert atmosphere; Reflux; Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 20℃; Reagent/catalyst; Temperature; |
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran | 90% |
With fac-1,2-bis(dipropylphosphaneyl)ethane tricarbonyl manganese(I) bromide; potassium tert-butylate; hydrogen In toluene at 100℃; under 37503.8 Torr; for 18h; Autoclave; | 72 %Chromat. |
2-chloro-4-pyridinenitrile
1-(3-aminophenyl)ethanone
2-((3-acetylphenyl)amino)isonicotinonitrile
Conditions | Yield |
---|---|
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 80℃; for 4h; Buchwald-Hartwig Coupling; Sealed tube; Inert atmosphere; | 90% |
2-chloro-4-pyridinenitrile
4-nitro-aniline
2-((4-nitrophenyl)amino)isonicotinonitrile
Conditions | Yield |
---|---|
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 80℃; for 4h; Buchwald-Hartwig Coupling; Sealed tube; Inert atmosphere; | 90% |
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With dihydrogen peroxide In dichloromethane; water at 20℃; for 3h; | 90% |
Conditions | Yield |
---|---|
With sodium methylate In methanol at 25℃; for 14h; | 90% |
2-chloro-4-pyridinenitrile
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 18h; Inert atmosphere; Schlenk technique; | 90% |
2-chloro-4-pyridinenitrile
iodobenzene
(2-chloropyridin-4-yl)(phenyl)methanone
Conditions | Yield |
---|---|
Stage #1: iodobenzene With n-butyllithium In diethyl ether; hexane at -78 - 0℃; for 0.75h; Inert atmosphere; Stage #2: 2-chloro-4-pyridinenitrile In diethyl ether; hexane at -78℃; for 1h; Stage #3: With hydrogenchloride In diethyl ether; hexane at -30℃; for 1h; | 90% |
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