Cas no. 399-95-1 Regorafenib Intermediate 4-Amino-3-fluorophenol Our products are high quality, good price, quick delivery time and we supply all customers best service in the long-term cooperation as below: 1.Established manufacturer. 2.Profession
zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed produc
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiry1111MicrosoftInternetExplorer402DocumentNotSpecified7.8 磅Normal0
Cas:399-95-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:399-95-1
Min.Order:1 Metric Ton
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Type:Manufacturers
inquiry4-Amino-3-Fluorophenol[CAS:399-95-1] Name 4-Amino-3-fluorophenol Synonyms 3-Fluoro-4-aminophenol HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corpor
good quality Appearance:brown powder Storage:cold storage Package:meet the demand of customer Application:diagnostic reagent Transportation:by sea or by air Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:399-95-1
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $0.9 / 1.0
Type:Lab/Research institutions
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $1300.0
Type:Lab/Research institutions
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $15.0 / 50.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:399-95-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry4-Amino-3-fluorophenol CAS:399-95-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte
Cas:399-95-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:399-95-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:399-95-1
Min.Order:1 Kilogram
FOB Price: $30.0 / 50.0
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:399-95-1
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiry4-Amino-3-fluorophenol is one of the most competitive products in our company, we can supply it with good quality and best price. Appearance:Brown to black solid Storage:Room temperature, Keep in Dark Place. Package:According to customer request Appl
Cas:399-95-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:399-95-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:399-95-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
Advantage 1: The product passed the professional production process and quality inspection, the purity is 99% +. 2: Highly qualified engineers to provide technical documents and service. 3: We could provide sample for your test. 4: High qualit
Cas:399-95-1
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
MolecularWeight: 127.1163 MolecularFormula: C6H6FNO … Appearance:Gray White Powder or Brown crystal Package:aluminium foil bag Application:pharmaceutical and research Transportation:No Special Requirements Port:Suzhou
Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:399-95-1
Min.Order:100 Gram
Negotiable
Type:Other
inquiryConditions | Yield |
---|---|
With hydrogen; palladium 10% on activated carbon In tetrahydrofuran; ethanol at 20℃; for 4.5h; | 100% |
With iron; acetic acid In ethyl acetate for 3h; Heating / reflux; | 98% |
With hydrogen; palladium 10% on activated carbon In ethyl acetate for 4h; | 97% |
N-(2-fluoro-4-hydroxyphenyl)acetamide
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With hydrogenchloride In water at 80℃; Inert atmosphere; | 88% |
aluminium hydride
sodium hydrogencarbonate
ortho-nitrofluorobenzene
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With sulfuric acid In water | 86% |
With sulfuric acid In water | 86% |
Conditions | Yield |
---|---|
With oxalic acid; aluminium In water at 80 - 85℃; for 1.5h; | 40.7% |
With sulfuric acid at 90℃; (electrochemical reduction); |
Conditions | Yield |
---|---|
With sodium dithionite; water |
O-(3-fluorophenyl)hydroxylamine
A
3-fluorophenol
B
4-amino-3-fluorophenol
C
2-amino-5-fluorophenol
D
2-amino-3-fluorophenol
Conditions | Yield |
---|---|
With trifluoroacetic acid at 70℃; for 6h; Product distribution; Rate constant; Kinetics; ΔH(excit.), ΔG(excit.), ΔS(excit.); |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 2: sodium dithionite; water View Scheme | |
Multi-step reaction with 2 steps 1: nitric acid / water / 0.5 h / 8 - 10 °C / Cooling with ice 2: sodium sulfide / 0.08 h / Microwave irradiation; Ionic liquid View Scheme |
Conditions | Yield |
---|---|
In water; acetic acid |
2-fluoro-4-hydroxyaniline hydrochloride
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; water |
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: copper(II) sulfate; sulfuric acid; water / 100 °C 2: nitric acid / water / 0.5 h / 8 - 10 °C / Cooling with ice 3: sodium sulfide / 0.08 h / Microwave irradiation; Ionic liquid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium nitrite / 1 h / Cooling with ice; Ionic liquid 1.2: 1 h 2.1: copper(II) sulfate; sulfuric acid; water / 100 °C 3.1: nitric acid / water / 0.5 h / 8 - 10 °C / Cooling with ice 4.1: sodium sulfide / 0.08 h / Microwave irradiation; Ionic liquid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sodium methylate / 5.5 h / 45 °C / Inert atmosphere 2: benzene; aluminum (III) chloride / 11 h / 45 °C 3: nickel(II) nitrate; palladium dichloride; tetrabutoxytitanium; hydrogen / ethanol / 2 h / 45 °C / 1500.15 Torr View Scheme |
4-amino-3-fluorophenol
acetic anhydride
N-(2-fluoro-4-hydroxyphenyl)acetamide
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-fluorophenol; acetic anhydride With acetic acid at 20℃; for 2h; Stage #2: With water at 20℃; for 0.5h; | 100% |
In 1,2-dichloro-ethane at 10 - 20℃; for 2.5h; | 95.8% |
In water | 66% |
In water | 66% |
Conditions | Yield |
---|---|
In sulfolane at 150℃; for 16h; | 98% |
4-bromo-pyridine-2-carboxylic acid methyl amide
4-amino-3-fluorophenol
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
Conditions | Yield |
---|---|
With N-benzyl-N,N,N-triethylammonium chloride; potassium iodide; sodium hydroxide In water at 30 - 70℃; for 2h; Reagent/catalyst; | 97.5% |
N-(6-methoxybenzo[d]thiazol-2-yl)-1H-imidazole-1-carboxamide
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide at 20℃; | 97% |
4-amino-3-fluorophenol
4-chloro-N-methylpicolinamide
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
Conditions | Yield |
---|---|
With potassium carbonate In 1,2-dichloro-ethane for 4h; Reflux; | 96.3% |
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In tetrahydrofuran at 20 - 30℃; for 2h; Stage #2: 4-chloro-N-methylpicolinamide In tetrahydrofuran Reagent/catalyst; Solvent; Temperature; Reflux; | 94% |
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In dimethyl amine at 20℃; for 2h; Inert atmosphere; Stage #2: 4-chloro-N-methylpicolinamide With potassium carbonate In dimethyl amine at 85℃; Time; Inert atmosphere; | 92% |
4-amino-3-fluorophenol
tert-butyldimethylsilyl chloride
Conditions | Yield |
---|---|
With 1H-imidazole In tetrahydrofuran at 20℃; for 12h; | 95% |
C11H7ClN4OS
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide at 20℃; | 94% |
methyl 4-formyl-2-methyl-benzoate
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
Stage #1: methyl 4-formyl-2-methyl-benzoate; 4-amino-3-fluorophenol With acetic acid at 20℃; for 2h; Stage #2: With sodium tris(acetoxy)borohydride at 20℃; Stage #3: With water; sodium hydrogencarbonate In ethyl acetate | 93% |
1H-indol-2-ylcarboxaldehyde
2-Butynoic acid
1,1,3,3-tetramethylbutane isonitrile
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With sodium sulfate In methanol at 20℃; Ugi Condensation; | 93% |
4-amino-3-fluorophenol
benzyl chloroformate
benzyl (2-fluoro-4-hydroxyphenyl)carbamate
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; | 92% |
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In tetrahydrofuran at 20℃; for 5h; | 92% |
With sodium tris(acetoxy)borohydride; acetic acid In tetrahydrofuran at 20℃; for 5h; | 92% |
Conditions | Yield |
---|---|
With potassium tert-butylate In N,N-dimethyl acetamide at 100℃; for 16h; | 92% |
4-amino-3-fluorophenol
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-fluorophenol With copper(l) iodide at 85℃; Stage #2: 4-chloro-2-pyridinecarboxamide hydrochloride for 6h; Temperature; Reagent/catalyst; | 91.1% |
di-tert-butyl dicarbonate
4-amino-3-fluorophenol
N-(2-fluoro-4-hydroxyphenyl)carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With indium(III) chloride at 35℃; for 2h; | 90% |
With indium(III) chloride at 35℃; for 2h; Neat (no solvent); | 90% |
indium(III) chloride at 35℃; for 2h; Neat (no solvent); | 90% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 24h; Cooling with ice; | 90% |
Conditions | Yield |
---|---|
In dichloromethane at 10 - 20℃; for 2.5h; | 89.8% |
4-chloro-6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinoline
4-amino-3-fluorophenol
3-Fluoro-4-{[6-methoxy-7-(3-morpholinopropoxy)-4-quinolyl]oxy}-aniline
Conditions | Yield |
---|---|
Stage #1: 4-chloro-6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinoline; 4-amino-3-fluorophenol With sodium t-butanolate In ISOPROPYLAMIDE at 95 - 100℃; for 18h; Industry scale; Stage #2: With aniline; sodium t-butanolate In ISOPROPYLAMIDE at 50 - 100℃; for 18h; Industry scale; Stage #3: With water In ISOPROPYLAMIDE at 20 - 30℃; Industry scale; | 89% |
With sodium t-butanolate In N,N-dimethyl acetamide at 95 - 100℃; for 36h; |
4-amino-3-fluorophenol
4-chloro-3-(trifluoromethyl)phenyl isocyanate
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea
Conditions | Yield |
---|---|
In dichloromethane; N,N-dimethyl-formamide at 20℃; for 16h; | 89% |
In dichloromethane for 6h; Reflux; | |
In dichloromethane at 20℃; for 16h; Inert atmosphere; Schlenk technique; | 401 mg |
Conditions | Yield |
---|---|
With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; toluene-4-sulfonic acid In tetrahydrofuran; acetonitrile at 120℃; under 23272.3 Torr; for 72h; regioselective reaction; | 88% |
Conditions | Yield |
---|---|
Stage #1: C22H28ClNO3 With methanesulfonyl chloride; triethylamine In 1,2-dichloro-ethane at 0 - 25℃; for 2h; Stage #2: 4-amino-3-fluorophenol In 1,2-dichloro-ethane at 85℃; for 12h; | 87% |
2,4-dichloropyridine
4-amino-3-fluorophenol
4-(2-chloro-pyridin-4-yloxy)-2-fluorophenylamine
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In ISOPROPYLAMIDE at 20℃; for 0.5h; Stage #2: 2,4-dichloropyridine In ISOPROPYLAMIDE at 80℃; for 12h; | 86% |
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In ISOPROPYLAMIDE at 20℃; for 0.5h; Stage #2: 2,4-dichloropyridine In ISOPROPYLAMIDE at 80℃; for 12h; | 86% |
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In N,N-dimethyl acetamide at 20℃; for 0.5h; Stage #2: 2,4-dichloropyridine In N,N-dimethyl acetamide at 80℃; for 12h; | 86% |
Stage #1: 4-amino-3-fluorophenol With potassium tert-butylate In N,N-dimethyl acetamide at 20℃; for 0.5h; Stage #2: 2,4-dichloropyridine In N,N-dimethyl acetamide at 85℃; for 4h; | 83% |
trifluoromethyl trifluorovinyl ether
4-amino-3-fluorophenol
2-fluoro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]-aniline
Conditions | Yield |
---|---|
With potassium hydroxide In dimethyl sulfoxide; toluene at 0℃; for 3h; | 85% |
1H-indol-2-ylcarboxaldehyde
2-Butynoic acid
tert-butylisonitrile
4-amino-3-fluorophenol
Conditions | Yield |
---|---|
With sodium sulfate In methanol at 20℃; Ugi Condensation; | 85% |
3-methoxyphenyl bromide
4-amino-3-fluorophenol
4-[(3-methoxyphenyl)amino]-3-fluorophenol
Conditions | Yield |
---|---|
With chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(ll); sodium t-butanolate In 1,4-dioxane at 110℃; for 3h; Inert atmosphere; | 84% |
4-methyl-1,2,3-thiadiazole-5-yl-formyl isocyanate
4-amino-3-fluorophenol
1-(2-fluoro-4-hydroxyphenyl)-3-[(4-methyl-1,2,3-thiadiazol-5-yl)carbonyl]urea
Conditions | Yield |
---|---|
In 1,2-dichloro-ethane at 20℃; for 8h; | 83% |
In 1,2-dichloro-ethane at 20℃; for 8.25h; | 83% |
Conditions | Yield |
---|---|
With 5-chloro-2-hydroxybenzoic acid; boric acid; palladium diacetate; 1,2-bis[di(t-butyl)phosphinomethyl]benzene In acetonitrile at 110℃; under 18100.7 Torr; for 48h; | 83% |
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