Products

Refine

Country

Business Type

Certificate

Display

Afine Chemicals Limited

Basic information Product Name: 3-ISOCHROMANONE Synonyms: ISOCHROMAN-3-ONE;3-ISOCHROMANONE;3-ketoneofdiffer;1,4-DIHYDRO-3H-2-BENZOPYRAN-3-ONE;3-ISOCHROMANONE 99+%;3-lsochroManone;2-HydroxyMethylphe

3-Isochromanone (CAS 4385-35-7)

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Isochromanone Manufacturer/High quality/Best price/In stock

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Isochromanone supplier in China

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory supply 3-Isochromanone

Cas:4385-35-7

Min.Order:1

Negotiable

Type:Other

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

3-Isochromanone

Cas:4385-35-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1,4-Dihydro-3H-2-benzopyran-3-one

Cas:4385-35-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 4385-35-7 with best quality

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

3-ISOCHROMANONE CAS4385-35-7

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

1. Best quality in your requirement 2. Competitive price in China market 3. mature Technical support 4. Professional logistic support 5 . Full experience of large numbers containers loading in Chinese sea port 6 Fast shipment by reputed shipping

3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $21.0 / 23.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 3-ISOCHROMANONE Synonyms: 1,4-DIHYDRO-3H-2-BENZOPYRAN-3-ONE;3-ISOCHROMANONE 99+%;3,4-Dihydro-1H-2-benzopyran-3-one;3-Isochromanone ,98.5%;3-lsochroManone;2-HydroxyMethylphenylaceticacid lacton

3-Isochromanone

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3H-2-Benzopyran-3-one,1,4-dihydro- 4385-35-7

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3-ISOCHROMANONE CAS:4385-35-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedia

3-ISOCHROMANONE CAS:4385-35-7

Cas:4385-35-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3H-2-Benzopyran-3-one,1,4-dihydro-

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3-Isochromanone

Cas:4385-35-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

3-Isochromanone CAS: 4385-35-7 Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard Shelf life 2 years Storage should be stored in a well-clos

Factory supply 3-Isochromanone

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3H-2-Benzopyran-3-one,1,4-dihydro-

Cas:4385-35-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3-Isochromanone

Cas:4385-35-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

CAS 4385-35-7 3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Metric Ton

FOB Price: $11000.0 / 12000.0

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 4385-35-7 3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Isochromanone

Cas:4385-35-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Supply Top quality 4385-35-7 Fast Delivery 3-isochromanone Molecular Formula C9H8O2 Molar Mass 148.16 Density 1.196±0.06 g/cm3(Predicted) Melting Point 80-82 °C (lit.) Boling Point

Supply Top quality 4385-35-7 Fast Delivery 3-isochromanone

Cas:4385-35-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3H-2-Benzopyran-3-one,1,4-dihydro-

Cas:4385-35-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3-Isochromanone

Cas:4385-35-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3-Isochromanone

Cas:4385-35-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

YUNBIO TECH CO.,LTD

Our Strength:-Flexible: We work in small teams with rapid communication channels. Respond quickly and efficiently to customer and market needs.-Innovative: We are focusing on the development of new products and keep close relationships with our custo

3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

4385-35-7 3-ISOCHROMANONE

Cas:4385-35-7

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3-Isochromanone CAS No.:4385-35-7 Molecule Formula:C9H8O2 Molecule Weight:148.16 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS SPEC

High Quality 3-Isochromanone in stock

Cas:4385-35-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

3-ISOCHROMANONE Chemical Properties Melting point 80-82 °C (lit.) Boiling point 130 °C / 1mmHg density 1.196±0.06 g/cm3(Predicted) BRN 123692 InChIKey ILHLUZUMRJQEAH-UHFFFAOYSA-N CAS DataBase Reference 4385-35-7(C

3-Isochromanone

Cas:4385-35-7

Min.Order:1 Gram

FOB Price: $65.0

Type:Lab/Research institutions

inquiry

Synthetic route

carbon monoxide
201230-82-2

carbon monoxide

(2-(bromomethyl)phenyl)methanol
74785-02-7

(2-(bromomethyl)phenyl)methanol

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; C52H46O2P2Pd2; triphenylphosphine In toluene at 60℃; under 760.051 Torr; for 2.16667h; Conversion of starting material;100%
With potassium carbonate; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran at 25℃; under 760 Torr; for 24h;71%
α,α'-dibromo-o-xylene
91-13-4

α,α'-dibromo-o-xylene

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
In tert-butyl alcohol95.1%
Multi-step reaction with 3 steps
1: methanol
2: zinc chloride; tetrachloromethane / Erhitzen des Reaktionsprodukts mit Kaliumcyanid in wss. Aethanol
3: aqueous sulfuric acid
View Scheme
α-chloro-α'-cyano-o-xylene
98590-71-7

α-chloro-α'-cyano-o-xylene

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

α-hydroxy-α'-cyano-o-xylene
67519-22-6

α-hydroxy-α'-cyano-o-xylene

Conditions
ConditionsYield
With hydrogenchloride In water at 150℃; under 3677.86 Torr; for 3h;A 95%
B n/a
2-indanone
615-13-4

2-indanone

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; for 240h;90%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 24h; Ambient temperature;90%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane90%
carbon monoxide
201230-82-2

carbon monoxide

phthalyl alcohol
612-14-6

phthalyl alcohol

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

o-xylene
95-47-6

o-xylene

C

o-methylphenylacetic acid
644-36-0

o-methylphenylacetic acid

Conditions
ConditionsYield
With hydrogen iodide; tetrakis(triphenylphosphine) palladium(0) In acetone at 90℃; under 68400 Torr; for 42h; Carbonylation; reduction;A 88%
B n/a
C 9%
With hydrogen iodide; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane at 120℃; under 68400 Torr; for 42h; Carbonylation; reduction;A 13%
B n/a
C 52%
carbon monoxide
201230-82-2

carbon monoxide

o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With water; N-ethyl-N,N-diisopropylamine In tert-Amyl alcohol at 40 - 70℃; under 3087.28 - 3475.15 Torr; Product distribution / selectivity;84.53%
With water; N-ethyl-N,N-diisopropylamine In tert-Amyl alcohol at 70℃; under 1551.49 Torr; Product distribution / selectivity;80.95%
With water; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium dichloride In tert-Amyl alcohol at 70 - 75℃; under 3863.02 Torr; for 4h; Product distribution / selectivity;75.4%
With water; N-ethyl-N,N-diisopropylamine; hydrogen tetrachloropalladate; triphenylphosphine In tert-Amyl alcohol at 70℃; under 3102.97 - 3863.02 Torr; for 2 - 4h; Product distribution / selectivity;69.9%
2-chloromethylphenylacetic acid
95335-46-9

2-chloromethylphenylacetic acid

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With sodium hydrogencarbonate In water at 50℃; for 0.5h; Temperature;84.1%
With hydrogenchloride; potassium hydrogencarbonate In fluorobenzene; cyclohexane
With potassium hydrogencarbonate In water at 50℃; pH=7.2; pH-value; Temperature; Reagent/catalyst;39 g
tert-Amyl alcohol
75-85-4

tert-Amyl alcohol

o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; dihydrotetrachloropalladium (H2PdCl4) In o-xylene; water83.9%
1,3-dihydroisobenzofuran
496-14-0

1,3-dihydroisobenzofuran

carbon dioxide
124-38-9

carbon dioxide

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With 4,4'-di-tert-butylbiphenyl; lithium In tetrahydrofuran 1.) 20 deg C, 0.5 h; 2.) -78 deg C, 1 h;82%
With naphthalene; lithium 1.) THF, 0 deg C, 2 h, 2.) THF, -40 deg C, 5 min; Yield given. Multistep reaction;
With naphthalene; lithium 1) THF, 0 deg C, 1.5 h, 2) THF, -40 deg C, 5 min; Yield given. Multistep reaction;
α-chloro-α'-cyano-o-xylene
98590-71-7

α-chloro-α'-cyano-o-xylene

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

α-carboxy-α'-hydroxy-o-xylene

α-carboxy-α'-hydroxy-o-xylene

C

α-aminocarboxy-α'-hydroxy-o-xylene

α-aminocarboxy-α'-hydroxy-o-xylene

D

α-hydroxy-α'-cyano-o-xylene
67519-22-6

α-hydroxy-α'-cyano-o-xylene

Conditions
ConditionsYield
With hydrogenchloride In water at 100℃; for 6h;A 76%
B n/a
C n/a
D n/a
In water at 150℃; under 3677.86 Torr; for 3h;A 75%
B n/a
C n/a
D n/a
tert-Amyl alcohol
75-85-4

tert-Amyl alcohol

o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

N-ethyl-N,N-diisopropylamine
7087-68-5

N-ethyl-N,N-diisopropylamine

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; triphenylphosphine; dihydrotetrachloropalladium (H2PdCl4) In o-xylene; water75.8%
tert-Amyl alcohol
75-85-4

tert-Amyl alcohol

o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

triphenylphosphine
603-35-0

triphenylphosphine

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; carbon monoxide; N-ethyl-N,N-diisopropylamine; palladium(II) chloride In water75.4%
2-(ethoxycarbonylmethyl)benzoic acid
22479-46-5

2-(ethoxycarbonylmethyl)benzoic acid

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With dimethylsulfide borane complex In tetrahydrofuran at 40℃; Inert atmosphere;75%
o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With hydrogenchloride; calcium hydroxide; carbon monoxide; triphenylphosphine In water; dichlorobis(triphenylphosphine)palladium[II]; tert-butyl alcohol72.9%
palladium(II) chloride In 1-methyl-pyrrolidin-2-one; water; tert-butyl alcohol66.4%
With hydrogenchloride; sodium hydroxide; carbon monoxide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium chloride (PdCl2) In o-xylene; water; tert-butyl alcohol
(±)-methyl 2-((3aR,6R,7aR)-1-oxo-6,7-dihydro-3H-3a,6-epoxyisobenzofuran-7a(1H)-yl)acetate

(±)-methyl 2-((3aR,6R,7aR)-1-oxo-6,7-dihydro-3H-3a,6-epoxyisobenzofuran-7a(1H)-yl)acetate

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In chloroform at 80℃; for 2h;70%
N-phenyl-maleimide
941-69-5

N-phenyl-maleimide

1,2-dihydrocyclobutabenzene-1-carboxylic acid
163222-89-7, 163222-90-0

1,2-dihydrocyclobutabenzene-1-carboxylic acid

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

(3aR,4S,9aR)-1,3-Dioxo-2-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole-4-carboxylic acid
138235-90-2, 138331-82-5

(3aR,4S,9aR)-1,3-Dioxo-2-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole-4-carboxylic acid

(3aS,4S,9aS)-1,3-Dioxo-2-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole-4-carboxylic acid
138235-90-2, 138331-82-5

(3aS,4S,9aS)-1,3-Dioxo-2-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole-4-carboxylic acid

Conditions
ConditionsYield
In benzene-d6 at 140℃; for 3h;A 19%
B 13%
C 68%
o-methylphenylacetic acid
644-36-0

o-methylphenylacetic acid

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
Stage #1: o-methylphenylacetic acid With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile) In fluorobenzene at 75 - 80℃; for 4h;
Stage #2: With potassium hydroxide; potassium hydrogencarbonate; potassium iodide In fluorobenzene; water at 60℃; pH=6.3; Conversion of starting material;
68%
With iodobenzene; 3-chloro-benzenecarboperoxoic acid; potassium bromide In 2,2,2-trifluoroethanol at 20℃; for 24h;67%
Stage #1: o-methylphenylacetic acid With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile) In chlorobenzene at 75 - 80℃; for 4h;
Stage #2: With potassium hydroxide; potassium hydrogencarbonate; potassium iodide In water; chlorobenzene at 60℃; pH=6.5; Conversion of starting material;
61.5%
o-(methoxycarbonylmethyl)benzoic acid
14736-50-6

o-(methoxycarbonylmethyl)benzoic acid

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
Stage #1: o-(methoxycarbonylmethyl)benzoic acid With borane In tetrahydrofuran at -15 - 20℃; for 16h;
Stage #2: With toluene-4-sulfonic acid In toluene at 80℃; for 3h;
66%
(±)-2-((3aR,6R,7aR)-1-oxo-6,7-dihydro-3H-3a,6-epoxyisobenzofuran-7a(1H)-yl)acetic acid

(±)-2-((3aR,6R,7aR)-1-oxo-6,7-dihydro-3H-3a,6-epoxyisobenzofuran-7a(1H)-yl)acetic acid

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In chloroform65%
2-(2-hydroxyethyl)benzyl alcohol
6346-00-5

2-(2-hydroxyethyl)benzyl alcohol

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

isochroman-1-one
4702-34-5

isochroman-1-one

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; [2,2]bipyridinyl; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; 9-azabicyclo<3.3.1>nonane-N-oxyl In acetonitrile at 22℃; for 2h; regioselective reaction;A 18%
B 58%
With iodosylbenzene; potassium bromide In water for 2h; sonication;
With [(η5-C5Me5)Ir(6,6'-dihydroxy-2,2'-bipyridine)(H2O)]OTf2 In water for 20h; Inert atmosphere; Reflux; Green chemistry; Overall yield = 88 %;
benzyl diazoacetate
52267-51-3

benzyl diazoacetate

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane for 24h;56%
carbon monoxide
201230-82-2

carbon monoxide

phthalyl alcohol
612-14-6

phthalyl alcohol

A

isochroman-3-one
4385-35-7

isochroman-3-one

B

o-methylphenylacetic acid
644-36-0

o-methylphenylacetic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); hydrogen iodide In acetone at 90℃; under 68400 Torr; for 42h;A 56%
B 9 % Spectr.
2-methyl-benzyl alcohol
89-95-2

2-methyl-benzyl alcohol

CO2

CO2

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With n-butyllithium In diethyl ether; hexane 1) 24 h, room temp. or 4 h reflux;53%
formic acid
64-18-6

formic acid

o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With N,N,N,N,-tetramethylethylenediamine; α,α′-bis(2-pyridyl(tert-butyl)phosphino)-o-xylene; palladium diacetate In N,N-dimethyl-formamide at 115℃; for 12h; Inert atmosphere;46%
o-Xylylene dichloride
612-12-4

o-Xylylene dichloride

triphenylphosphine
603-35-0

triphenylphosphine

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
palladium(II) chloride In water; tert-butyl alcohol24%
α-chloro-α'-cyano-o-xylene
98590-71-7

α-chloro-α'-cyano-o-xylene

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With sodium hydroxide In water at 100℃; for 6h;3%
3H-3,8A-methano-benzo[c][1,2]dioxin
172-57-6

3H-3,8A-methano-benzo[c][1,2]dioxin

1-methyl-4-nitrosobenzene
623-11-0

1-methyl-4-nitrosobenzene

isochroman-3-one
4385-35-7

isochroman-3-one

(2-methoxymethyl-phenyl)-acetonitrile
408535-88-6

(2-methoxymethyl-phenyl)-acetonitrile

isochroman-3-one
4385-35-7

isochroman-3-one

Conditions
ConditionsYield
With hydrogen bromide
With sulfuric acid
methanol
67-56-1

methanol

isochroman-3-one
4385-35-7

isochroman-3-one

methyl 2-(chloromethyl)phenylacetate
95360-33-1

methyl 2-(chloromethyl)phenylacetate

Conditions
ConditionsYield
With thionyl chloride In 5,5-dimethyl-1,3-cyclohexadiene; N,N-dimethyl-formamide at 20 - 30℃; for 4h; Solvent;100%
With hydrogenchloride at 20 - 26℃; for 2.5h;98%
With thionyl chloride at 20℃; Cooling with ice;96%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

isochroman-3-one
4385-35-7

isochroman-3-one

((1H-isochromen-3-yl)oxy)trimethylsilane
87532-04-5

((1H-isochromen-3-yl)oxy)trimethylsilane

Conditions
ConditionsYield
Stage #1: isochroman-3-one With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.533333h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere; Enzymatic reaction;
99%
With n-butyllithium; diisopropylamine 1.) THF, -78 deg C, 10 min, 2.) 3 h, warm. to RT; Yield given. Multistep reaction;
isochroman-3-one
4385-35-7

isochroman-3-one

methylamine
74-89-5

methylamine

2-(2-(hydroxymethyl)phenyl)-N-methylacetamide
218131-53-4

2-(2-(hydroxymethyl)phenyl)-N-methylacetamide

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 8h;99%
In tetrahydrofuran at 20℃; for 8h;93%
isochroman-3-one
4385-35-7

isochroman-3-one

2-(2-hydroxyethyl)benzyl alcohol
6346-00-5

2-(2-hydroxyethyl)benzyl alcohol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 3h; Inert atmosphere;99%
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 3h; Inert atmosphere;99%
With phenylsilane; potassium hydroxide In tetrahydrofuran for 4h; Schlenk technique; Inert atmosphere; Reflux;60%
With samarium diiodide; water In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;65 %Spectr.
isochroman-3-one
4385-35-7

isochroman-3-one

ethanol
64-17-5

ethanol

ethyl 2-(2-(bromomethyl)phenyl)acetate
39191-76-9

ethyl 2-(2-(bromomethyl)phenyl)acetate

Conditions
ConditionsYield
With phosphorus tribromide98%
With hydrogen bromide90%
With hydrogen bromide at 20℃; for 48h; Ring cleavage; esterification;
isochroman-3-one
4385-35-7

isochroman-3-one

methyl 2-(chloromethyl)phenylacetate
95360-33-1

methyl 2-(chloromethyl)phenylacetate

Conditions
ConditionsYield
With hydrogenchloride In methanol; dichloromethane98%
With thionyl chloride; potassium hydrogencarbonate In methanol; toluene
Multi-step reaction with 2 steps
1: thionyl chloride / 4 h / Reflux; Heating
2: 1 h / 20 °C / Cooling with ice
View Scheme
isochroman-3-one
4385-35-7

isochroman-3-one

o-methylphenylacetic acid
644-36-0

o-methylphenylacetic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; W(OTf)6; hydrogen; acetic acid at 50℃; under 760.051 Torr; for 12h;98%
With palladium on activated carbon; W(OTf)6; hydrogen In acetic acid at 50℃; under 760.051 Torr; for 12h;97%
isochroman-3-one
4385-35-7

isochroman-3-one

2-methyl-benzyl alcohol
89-95-2

2-methyl-benzyl alcohol

3-[(2'-hydroxymethyl)phenyl]coumarin

3-[(2'-hydroxymethyl)phenyl]coumarin

Conditions
ConditionsYield
With piperidine at 140℃; for 1h; Knoevenagel condensation;97%
isochroman-3-one
4385-35-7

isochroman-3-one

4-chlorobenzylamine
104-86-9

4-chlorobenzylamine

1,4-dihydro-2-(4-chlorophenylmethyl)-3(2H)-isoquinolinone

1,4-dihydro-2-(4-chlorophenylmethyl)-3(2H)-isoquinolinone

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium acetate In toluene at 110℃; for 36h; Inert atmosphere; Glovebox; Molecular sieve; Schlenk technique;97%
isochroman-3-one
4385-35-7

isochroman-3-one

4-diazo-3-isochromanone

4-diazo-3-isochromanone

Conditions
ConditionsYield
Stage #1: isochroman-3-one With sodium azide; p-toluenesulfonyl chloride In acetonitrile at 20℃;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 0 - 20℃;
96%
With 4-toluenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 0℃;81%
With 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 0 - 20℃; for 1h;60%
isochroman-3-one
4385-35-7

isochroman-3-one

Methyl formate
107-31-3

Methyl formate

methyl (E)-3-methoxy-2-(2-chloromethylphenyl)acrylate
117428-51-0

methyl (E)-3-methoxy-2-(2-chloromethylphenyl)acrylate

Conditions
ConditionsYield
With acetic acid Heating;96%
isochroman-3-one
4385-35-7

isochroman-3-one

para-methylbenzylamine
104-84-7

para-methylbenzylamine

1,4-dihydro-2-(4-methylphenylmethyl)-3(2H)-isoquinolinone

1,4-dihydro-2-(4-methylphenylmethyl)-3(2H)-isoquinolinone

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium acetate In toluene at 110℃; for 36h; Inert atmosphere; Glovebox; Molecular sieve; Schlenk technique;95%
isochroman-3-one
4385-35-7

isochroman-3-one

3,4-dihydro-1H-2-benzopyran-3-ol
42900-89-0

3,4-dihydro-1H-2-benzopyran-3-ol

Conditions
ConditionsYield
With diisobutylaluminium hydride In toluene at -60 - -10℃;94%
With diisobutylaluminium hydride In dichloromethane at -78℃; for 3h;91%
With lithium aluminium tetrahydride In tetrahydrofuran at -78℃; for 1h; Reduction;
With diisobutylaluminium hydride In dichloromethane; toluene at -78℃; for 2h;
With diisobutylaluminium hydride In dichloromethane at -78℃; for 2h; Inert atmosphere;
isochroman-3-one
4385-35-7

isochroman-3-one

o-(bromomethyl)phenylacetic acid
13737-35-4

o-(bromomethyl)phenylacetic acid

Conditions
ConditionsYield
With hydrogen bromide In acetic acid93%
With hydrogen bromide In acetic acid at 20 - 70℃; for 3h;93%
With hydrogen bromide; acetic acid at 70℃; for 1h;88%
With hydrogen bromide In acetic acid 1.) 20 deg C, 2 h; 2.) 70 deg C, 1 h;
With hydrogen bromide In water
isochroman-3-one
4385-35-7

isochroman-3-one

3-(3,4-dimethoxyphenyl)propylamine
14773-42-3

3-(3,4-dimethoxyphenyl)propylamine

N-<3-(3,4-Dimethoxyphenyl)propyl><2-(hydroxymethyl)phenyl>acetamid
166537-41-3

N-<3-(3,4-Dimethoxyphenyl)propyl><2-(hydroxymethyl)phenyl>acetamid

Conditions
ConditionsYield
In ethanol for 3h; Heating;92%
isochroman-3-one
4385-35-7

isochroman-3-one

benzylamine
100-46-9

benzylamine

1,4-dihydro-2-(phenylmethyl)-3(2H)-isoquinolinone
6772-73-2

1,4-dihydro-2-(phenylmethyl)-3(2H)-isoquinolinone

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium acetate In toluene at 110℃; for 36h; Inert atmosphere; Glovebox; Molecular sieve; Schlenk technique;92%
With aluminium trichloride at 160℃; for 20h;73%
isochroman-3-one
4385-35-7

isochroman-3-one

methyl iodide
74-88-4

methyl iodide

3,4-dihydro-4-methyl-(3H)-2-benzopyran-3-one
122571-80-6

3,4-dihydro-4-methyl-(3H)-2-benzopyran-3-one

Conditions
ConditionsYield
Stage #1: isochroman-3-one With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: methyl iodide at -78℃; for 1h;
90%
isochroman-3-one
4385-35-7

isochroman-3-one

trimethyl orthoformate
149-73-5

trimethyl orthoformate

(E)-3,3-dimethoxy-4-(methoxymethylene)isochroman

(E)-3,3-dimethoxy-4-(methoxymethylene)isochroman

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In methanol at 40℃; for 24h; Solvent; Temperature; Concentration; Reagent/catalyst;90%
isochroman-3-one
4385-35-7

isochroman-3-one

3-(3-methoxyphenyl)propan-1-amine
18655-52-2

3-(3-methoxyphenyl)propan-1-amine

<2-(Hydroxymethyl)phenyl>-N-<3-(3-methoxyphenyl)propyl>acetamid

<2-(Hydroxymethyl)phenyl>-N-<3-(3-methoxyphenyl)propyl>acetamid

Conditions
ConditionsYield
In ethanol for 3h; Heating;88%
isochroman-3-one
4385-35-7

isochroman-3-one

2-methoxyacetonitrile
1738-36-9

2-methoxyacetonitrile

C12H13NO3
1179322-20-3

C12H13NO3

Conditions
ConditionsYield
With heptahydridobis(triphenylphosphine)rhenium In tetrahydrofuran at 150℃; for 5h; Inert atmosphere; teflon-cocked sealed tube;88%
isochroman-3-one
4385-35-7

isochroman-3-one

cyclohexa-1,3-diene
1165952-91-9

cyclohexa-1,3-diene

4-(cyclohex-2-enyl)isochroman-3-one

4-(cyclohex-2-enyl)isochroman-3-one

Conditions
ConditionsYield
With allyl(cyclopentadiene)palladium(II); 1,3-bis(dicyclohexylphosphine)propane In 1,2-dimethoxyethane at 80℃; for 18h;87%
isochroman-3-one
4385-35-7

isochroman-3-one

ethyl cyanoformate
623-49-4

ethyl cyanoformate

ethyl 3-oxoisochroman-4-carboxylate
72206-74-7

ethyl 3-oxoisochroman-4-carboxylate

Conditions
ConditionsYield
Stage #1: isochroman-3-one With lithium diisopropyl amide Inert atmosphere;
Stage #2: ethyl cyanoformate Claisen condensation;
87%
isochroman-3-one
4385-35-7

isochroman-3-one

3-benzyloxy-4-methoxyphenylethylamine
36455-21-7

3-benzyloxy-4-methoxyphenylethylamine

N-<2-(3-benzyloxy-4-methoxyphenyl)-ethyl>-(2-hydroxymethyl)phenylacetamide
98988-21-7

N-<2-(3-benzyloxy-4-methoxyphenyl)-ethyl>-(2-hydroxymethyl)phenylacetamide

Conditions
ConditionsYield
In ethanol for 24h; Ambient temperature;86%
isochroman-3-one
4385-35-7

isochroman-3-one

4-methoxy-benzylamine
2393-23-9

4-methoxy-benzylamine

1,4-dihydro-2-(4-methoxyphenylmethyl)-3(2H)-isoquinolinone

1,4-dihydro-2-(4-methoxyphenylmethyl)-3(2H)-isoquinolinone

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium acetate In toluene at 110℃; for 36h; Inert atmosphere; Glovebox; Molecular sieve; Schlenk technique;85%

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View