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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

DL-Tryptophan Manufacturer/High quality/Best price/In stock

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White to off-white powder Conforms Assay 98%min

High quality 54-12-6 DL-Trytophan

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Dl-Tryptophan supplier in China

Cas:54-12-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Dl-Tryptophan

Cas:54-12-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic TRYPTOPHAN 54-12-6 Manufacturer

Cas:54-12-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

DL-Tryptophan Product Name: DL-Tryptophan CAS NO.: 54-12-6 Chemical Structure: Molecular Formula: C11H12N2O2 Molecular Weight: 204.23

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

DL-Tryptophan

Cas:54-12-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: DL-Tryptophan Synonyms: (rs)-tryptophan;2-Amino-3,3’-IndolylpropanoicAcid;DL-Trytophan;DL-Trytophane;Racemic Tryptophan;DL-TRYPTOPHAN-2-13C;(±)-α-Amino-3-indol

DL-Tryptophan 54-12-6

Cas:54-12-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Dl-Tryptophan : 54-12-6

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 54-12-6 with best quality

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

DL-Tryptophan 54-12-6

Cas:54-12-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: DL-Tryptophan Structure: Formula: C11H12N2O2 Molecular Weight : 204.23 Synonyms: (rs)-tryptophan;2-Amino-3,3’-IndolylpropanoicAcid;DL-Trytophan;DL-Tr

Factory Supply DL-Tryptophan

Cas:54-12-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Minstar Chemical Co., Ltd

roduct Name: DL-Tryptophan CAS: 54-12-6 MF: C11H12N2O2 MW: 204.23 EINECS: 200-194-9 Mol File: 54-12-6.mol DL-Tryptophan Structure DL-Tryptophan Chemical Properties Melting point 289-290 °C (dec.)(lit.) alpha [α]D

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

DL-Trytophan/CAS:54-12-6

Cas:54-12-6

Min.Order:5 Gram

FOB Price: $18.0 / 60.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

DL-Tryptophan CAS:54-12-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

DL-Tryptophan CAS:54-12-6

Cas:54-12-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory Supply DL-Tryptophan CAS 54-12-6

Cas:54-12-6

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

DL-Tryptophan

Cas:54-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's custo

BEST PRICE/DL-Tryptophan

Cas:54-12-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

DL-Tryptophan

Cas:54-12-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

DL-TRYPTOPHAN

Cas:54-12-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Dl-Tryptophan

Cas:54-12-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

DL-TryptophanAppearance:white powder Storage:sealed, keep in the ventilated, dry Package:according to customers' requirements Application:health care Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or accor

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Gram

Negotiable

Type:Other

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:white or off-white powder or crystals Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Essential amino acid. Transporta

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

DL-Tryptophan

Cas:54-12-6

Min.Order:0

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

DL-Tryptophan

Cas:54-12-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

DL-Tryptophan

Cas:54-12-6

Min.Order:0

Negotiable

Type:Manufacturers

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

DL-Tryptophan

Cas:54-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

DL-γ-glutamaldehydic acid dimethyl acetal
70380-01-7

DL-γ-glutamaldehydic acid dimethyl acetal

phenylhydrazine hydrochloride
59-88-1

phenylhydrazine hydrochloride

Conditions
ConditionsYield
With sulfuric acid In water for 1h; Heating;85%
rac-3-(1H-indol-3-yl)-2-(benzoylamino)propionic acid methyl ester
104331-05-7

rac-3-(1H-indol-3-yl)-2-(benzoylamino)propionic acid methyl ester

Conditions
ConditionsYield
In potassium hydroxide hydrolysis;70%
α-(hydroxyimino)-β-(indol-3-yl)propionic acid
60438-65-5

α-(hydroxyimino)-β-(indol-3-yl)propionic acid

Conditions
ConditionsYield
With ethanol; nickel Hydrogenation;
With ammonia; water at 60℃;
5-(3-indolylmethylene)hydantoin
117490-34-3

5-(3-indolylmethylene)hydantoin

Conditions
ConditionsYield
With diammonium sulfide at 100℃;
With diammonium sulfide at 150℃;
formylamino-indol-3-ylmethyl-malonic acid
860375-04-8

formylamino-indol-3-ylmethyl-malonic acid

Conditions
ConditionsYield
With sodium hydroxide; water
acetylamino-indol-3-ylmethyl-malonic acid
4354-88-5

acetylamino-indol-3-ylmethyl-malonic acid

Conditions
ConditionsYield
With sulfuric acid; water
Multi-step reaction with 2 steps
1: H2O
2: NaOH; water
View Scheme
ethyl 2-formamido-3-(3-indolyl)-2-carbethoxypropionate
64258-95-3

ethyl 2-formamido-3-(3-indolyl)-2-carbethoxypropionate

Conditions
ConditionsYield
With sodium hydroxide; water at 120℃; anschl. mit Essigsaeure;
Multi-step reaction with 2 steps
1: aq.-ethanolic NaOH
2: H2O; NaOH
View Scheme
Nα-ethoxycarbonyl-DL-tryptophan-nitrile
854885-91-9

Nα-ethoxycarbonyl-DL-tryptophan-nitrile

Conditions
ConditionsYield
With hydrogenchloride; water; acetic acid
indol-3-ylmethyl-phthalimido-malonic acid diethyl ester

indol-3-ylmethyl-phthalimido-malonic acid diethyl ester

Conditions
ConditionsYield
With sodium hydroxide; water
Nα-ethoxycarbonyl-DL-tryptophan-ethyl ester
149828-46-6

Nα-ethoxycarbonyl-DL-tryptophan-ethyl ester

Conditions
ConditionsYield
With sodium hydroxide; ethanol; water
L-Tryptophan
73-22-3

L-Tryptophan

Conditions
ConditionsYield
With barium dihydroxide at 170℃; im Autoklaven;
With hydrogenchloride; ethanethiol at 110℃; Rate constant; various times;
With 0.1-diethanolamine-HCl buffer; cross-linked formylated phenol-formaldehyde resin at 70℃; Rate constant; other reagents;
With hydrogenchloride at 110℃; Product distribution; Kinetics; racemization reaction;
N-acetyl-DL-tryptophan
1218-34-4, 87-32-1

N-acetyl-DL-tryptophan

Conditions
ConditionsYield
With barium dihydroxide; water
With sodium hydroxide; water
With water; sodium hydroxide at 85℃; for 1.5h; pH=9.5; pH-value; Temperature;23.2 g
With sodium hydroxide; water
acetyltryptophan ethylester
42717-06-6

acetyltryptophan ethylester

Conditions
ConditionsYield
With sodium hydroxide; water
2-(benzoylamino)-3-(indol-3-yl)propanoic acid
2901-79-3

2-(benzoylamino)-3-(indol-3-yl)propanoic acid

Conditions
ConditionsYield
With barium dihydroxide; water
indole
120-72-9

indole

serin
302-84-1

serin

Conditions
ConditionsYield
With N+C3(R/S-DHBN)(S-Ala)2C16; N+C5(S-Ala)2C16; PL+C2N2C16; copper(II) perchlorate In water at 30℃; for 200h; Product distribution; Mechanism; var. catalyst composition;
indole
120-72-9

indole

3-chloro-DL-alanine
3981-36-0

3-chloro-DL-alanine

Conditions
ConditionsYield
With aluminum(III) sulfate; pyridoxal; β-cyclodextrin at 100℃; for 0.5h; pH=5.2;
indole
120-72-9

indole

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

Conditions
ConditionsYield
With sodium hydroxide; pyridoxal 5'-phosphate; ammonium chloride; Triton X-100 In ethanol at 32℃; for 72h; Enterobacter aerogenes L-12;
Indole-3-pyruvic acid
392-12-1

Indole-3-pyruvic acid

Conditions
ConditionsYield
With pyridoxamine; β‐cyclodextrin pH 8, other reagent;
With methylated polyethyleneimine-lauryl supported pyridoxamine at 30℃; pH=7.5; Kinetics;

A

(+/-)-Nι-Formyltryptophan
74257-18-4

(+/-)-Nι-Formyltryptophan

B

Trp
54-12-6

Trp

Conditions
ConditionsYield
With p-cresol; dimethylsulfide; hydrogen fluoride at 0℃; for 1h; Product distribution; further reagent: EtSH, HSCH2CH2SH, p-thiocresol; var. time;A 98 % Chromat.
B 2 % Chromat.
Conditions
ConditionsYield
With formic acid; water; acetic acid for 0.0166667h; Product distribution; Ambient temperature; other reaction time;21 % Chromat.
isopropyl (+/-)-tryptophanoate
81084-87-9

isopropyl (+/-)-tryptophanoate

A

isopropyl alcohol
67-63-0

isopropyl alcohol

B

Trp
54-12-6

Trp

Conditions
ConditionsYield
With water; β‐cyclodextrin In acetonitrile for 30h; Rate constant; Ambient temperature; var. pH, other β-cyclodextrin derivatives;
α-benzamino-β--acrylic acid

α-benzamino-β--acrylic acid

Conditions
ConditionsYield
With ethanol; sodium Verseifen des Reaktionsprodukts durch Verduennen mit Wasser; dl-tryptophan;
(+-)-2-acetylamino-3-<2-ethoxycarbonyl-indol-3-yl>-propionic acid

(+-)-2-acetylamino-3-<2-ethoxycarbonyl-indol-3-yl>-propionic acid

Conditions
ConditionsYield
With sulfuric acid; water
With sulfuric acid; water
(+-)-3-indol-3-yl-2-nitro-propionic acid ethyl ester

(+-)-3-indol-3-yl-2-nitro-propionic acid ethyl ester

Conditions
ConditionsYield
With ethanol; nickel at 100℃; Hydrogenation.unter erhoehtem Druck; anschl. mit wss. NaOH;
(+-)-3-indol-3-yl-2-nitro-propionic acid methyl ester

(+-)-3-indol-3-yl-2-nitro-propionic acid methyl ester

Conditions
ConditionsYield
With methanol; nickel at 80 - 90℃; Hydrogenation.unter erhoehtem Druck; anschl. mit wss. NaOH;
(+-)-5-indol-3-ylmethyl-imidazolidine-2,4-dione

(+-)-5-indol-3-ylmethyl-imidazolidine-2,4-dione

Conditions
ConditionsYield
With barium dihydroxide; water
With sodium hydroxide; water
With barium dihydroxide; water
5--hydantoin

5--hydantoin

Conditions
ConditionsYield
With barium dihydroxide at 108℃;
Conditions
ConditionsYield
With hydrogenchloride; 3 A molecular sieve for 2.5h; Heating;100%
With thionyl chloride at 10 - 25℃; Cooling with ice;100%
With thionyl chloride at -15 - 20℃; for 24h; Saturated gas; Inert atmosphere;92%
ethanol
64-17-5

ethanol

DL-tryptophan ethyl ester
6519-66-0, 7479-05-2, 74126-25-3

DL-tryptophan ethyl ester

Conditions
ConditionsYield
Stage #1: ethanol; Trp With thionyl chloride Reflux;
Stage #2: With sodium hydrogencarbonate
100%
With thionyl chloride at 0 - 80℃; Reflux;91%
With thionyl chloride for 0.5h; Reflux;76%
1,8-diazabicyclo[5.4.0]undec-7-ene
6674-22-2

1,8-diazabicyclo[5.4.0]undec-7-ene

2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepin-1-ium (D,L)-2-amino-3-(1H-indol-3-yl)propanoate

2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepin-1-ium (D,L)-2-amino-3-(1H-indol-3-yl)propanoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 20h;100%
N,N,N',N'-tetramethylguanidine
80-70-6

N,N,N',N'-tetramethylguanidine

bis(dimethylamino)methaniminium DL-2-amino-3-(1H-indol-3-yl)propanoate

bis(dimethylamino)methaniminium DL-2-amino-3-(1H-indol-3-yl)propanoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 23h;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 24h;99%
With triethylamine In water at 45℃; for 12h; Solvent; Temperature;95.1%
With sodium carbonate In 1,4-dioxane; water at 20℃;91%
nickel(II) nitrate hexahydrate

nickel(II) nitrate hexahydrate

(S)-N-(2-benzoyl-4-chlorophenyl)-2-(1-(1-adamantyl)ethylamino)acetamide

(S)-N-(2-benzoyl-4-chlorophenyl)-2-(1-(1-adamantyl)ethylamino)acetamide

C38H39ClN4NiO3

C38H39ClN4NiO3

Conditions
ConditionsYield
With potassium carbonate In methanol for 2h; Reflux;99%
2-amino-3-(1H-indol-3-yl)propan-1-ol
154-09-6, 526-53-4, 2899-29-8, 52485-52-6

2-amino-3-(1H-indol-3-yl)propan-1-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 15h; Heating;98%
With tetrahydrofuran; lithium aluminium tetrahydride
With sodium tetrahydroborate; iodine In tetrahydrofuran Heating;
In tetrahydrofuran; ethyl acetate
3-hydroxy-3-methyl-1-cyano-1-butyne
32837-87-9

3-hydroxy-3-methyl-1-cyano-1-butyne

2-[(5-imino-2,2-dimethyl-2,5-dihydrofuran-3-yl)amino]-3-(1H-indol-3-yl)propanoic acid
1257081-06-3

2-[(5-imino-2,2-dimethyl-2,5-dihydrofuran-3-yl)amino]-3-(1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
Stage #1: Trp With sodium hydroxide In water at 40 - 45℃; pH=10;
Stage #2: 3-hydroxy-3-methyl-1-cyano-1-butyne In water for 4h; pH=10; regioselective reaction;
98%
((S)-N-(2-benzoyl-4-chlorophenyl)-1-(3,4-dichlorobenzyl)pyrrolidine-2-carboxamide)
1644308-41-7

((S)-N-(2-benzoyl-4-chlorophenyl)-1-(3,4-dichlorobenzyl)pyrrolidine-2-carboxamide)

nickel(II) acetate tetrahydrate
6018-89-9

nickel(II) acetate tetrahydrate

C36H29Cl3N4NiO3

C36H29Cl3N4NiO3

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 72h; Temperature; diastereoselective reaction;98%
methanol
67-56-1

methanol

methyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride

methyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride for 18h; Reflux;98%
With thionyl chloride at 0 - 60℃;
With thionyl chloride
3-(4,4-difluoro-2,6-dimethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)propionic acid succinimidyl ester

3-(4,4-difluoro-2,6-dimethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)propionic acid succinimidyl ester

N-(3-(4,4-difluoro-2,6-dimethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)propanoyl)-DL-tryptophan

N-(3-(4,4-difluoro-2,6-dimethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)propanoyl)-DL-tryptophan

Conditions
ConditionsYield
In dimethyl sulfoxide at 2℃; for 12h; pH=11;98%
formaldehyd
50-00-0

formaldehyd

1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid
6052-68-2

1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In water for 3h; Heating;97%
In water at 37℃; Pictet-Spengler reaction;95%
With sodium hydroxide In water at 37℃; Formylation;90%
phthalic anhydride
85-44-9

phthalic anhydride

2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid
32675-71-1

2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 8h; Reflux; Inert atmosphere;97%
With pyridine
With pyridine for 18h; Reflux;26.9 g
3,5-di-tert-butyl-4-hydroxybenzyl acetate
14387-17-8

3,5-di-tert-butyl-4-hydroxybenzyl acetate

2-(3,5-di-tert-butyl-4-hydroxybenzylamino)-3-(1H-indol-3-yl)propanoic acid

2-(3,5-di-tert-butyl-4-hydroxybenzylamino)-3-(1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
In dimethyl sulfoxide at 70℃; for 3h;97%
3-nitro-2-(trifluoromethyl)-2H-chromene
890095-37-1

3-nitro-2-(trifluoromethyl)-2H-chromene

indole-2,3-dione
91-56-5

indole-2,3-dione

(1S*,3S*,3aS*,4S*,9bR*)-3-[(1H-indol-3-yl)methyl]-3a-nitro-4-(trifluoromethyl)-2,3,3a,9b-tetrahydro-4H-spiro[chromeno[3,4-c]pyrrole-1,3'-indolin]-2'-one

(1S*,3S*,3aS*,4S*,9bR*)-3-[(1H-indol-3-yl)methyl]-3a-nitro-4-(trifluoromethyl)-2,3,3a,9b-tetrahydro-4H-spiro[chromeno[3,4-c]pyrrole-1,3'-indolin]-2'-one

Conditions
ConditionsYield
In ethanol at 70℃; for 3h; diastereoselective reaction;96%
dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

dimethyl 4-hydroxy-5-(1H-indol-3-ylmethyl)-1H-pyrrole-2,3-dicarboxylate

dimethyl 4-hydroxy-5-(1H-indol-3-ylmethyl)-1H-pyrrole-2,3-dicarboxylate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 25℃; for 24h;95%
acetylenedicarboxylic acid diethyl ester
762-21-0

acetylenedicarboxylic acid diethyl ester

diethyl 4-hydroxy-5-(1H-indol-3-ylmethyl)-1H-pyrrole-2,3-dicarboxylate
1067227-64-8

diethyl 4-hydroxy-5-(1H-indol-3-ylmethyl)-1H-pyrrole-2,3-dicarboxylate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 25℃; for 24h;95%
3-(1-hydroxycyclohexyl)prop-2-ynenitrile
32837-89-1

3-(1-hydroxycyclohexyl)prop-2-ynenitrile

2-[(2-imino-1-oxaspiro[4.5]dec-3-en-4-yl)amino]-3-(1H-indol-3-yl)propanoic acid
1257081-08-5

2-[(2-imino-1-oxaspiro[4.5]dec-3-en-4-yl)amino]-3-(1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
Stage #1: Trp With sodium hydroxide In water at 40 - 45℃; pH=10;
Stage #2: 3-(1-hydroxycyclohexyl)prop-2-ynenitrile In water for 48h; pH=10; regioselective reaction;
95%
3-hydroxy-3-tetramethylene-1-propynecarbonitrile
32837-90-4

3-hydroxy-3-tetramethylene-1-propynecarbonitrile

2-[(2-imino-1-oxaspiro[4.4]non-3-en-4-yl)amino]-3-(1H-indol-3-yl)propanoic acid

2-[(2-imino-1-oxaspiro[4.4]non-3-en-4-yl)amino]-3-(1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
Stage #1: Trp With sodium hydroxide In water at 40 - 45℃; pH=10;
Stage #2: 3-hydroxy-3-tetramethylene-1-propynecarbonitrile In water for 48h; pH=10; regioselective reaction;
95%
(S)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphth[2,1-c:1′,2′-e]azepin-4-yl]acetamide

(S)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphth[2,1-c:1′,2′-e]azepin-4-yl]acetamide

nickel(II) acetate tetrahydrate
6018-89-9

nickel(II) acetate tetrahydrate

C48H35ClN4NiO3

C48H35ClN4NiO3

Conditions
ConditionsYield
With potassium carbonate In methanol at 60 - 70℃; for 24h;95%
1-benzylisatin
1217-89-6

1-benzylisatin

(E)-2-benzylidene-2,3-dihydro-1H-inden-1-one
5706-12-7

(E)-2-benzylidene-2,3-dihydro-1H-inden-1-one

C41H33N3O2

C41H33N3O2

Conditions
ConditionsYield
In dimethyl sulfoxide at 28℃; for 6h; Inert atmosphere; diastereoselective reaction;95%
methanol
67-56-1

methanol

DL-tryptophan methyl ester
7303-49-3

DL-tryptophan methyl ester

Conditions
ConditionsYield
With thionyl chloride at 20℃;94%
With hydrogenchloride
With thionyl chloride for 2h; Heating;
pyridoxal hydrochloride
65-22-5

pyridoxal hydrochloride

pyridoxylidenetryptophan Schiff base
13311-34-7

pyridoxylidenetryptophan Schiff base

Conditions
ConditionsYield
In ethanol at 5℃;94%
In ethanol; water at 25℃; pH=6.7 - 7.0;75%
dimethoxyacetaldehyde
51673-84-8

dimethoxyacetaldehyde

1-(dimethoxymethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

1-(dimethoxymethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane for 1h;94%
With trifluoroacetic acid In dichloromethane at 20℃; for 1h;94%
orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

3-(1H-indol-3-yl)-2-(1H-tetrazol-yl)propanoic acid

3-(1H-indol-3-yl)-2-(1H-tetrazol-yl)propanoic acid

Conditions
ConditionsYield
With sodium azide In water at 40℃; for 1h; Catalytic behavior; Solvent; Temperature; Concentration;94%
Conditions
ConditionsYield
With thionyl chloride In methanol at 20℃;92.54%
With thionyl chloride In methanol
1,2-Cyclohexanedicarboxylic acid-anhydride
85-42-7

1,2-Cyclohexanedicarboxylic acid-anhydride

2-(1,3-dioxooctahydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid

2-(1,3-dioxooctahydroisoindol-2-yl)-3-(1H-indol-3-yl)propionic acid

Conditions
ConditionsYield
With pyridine for 12h; Heating;92%
6-methoxy-3-nitro-2-trifluoromethyl-2H-chromene
1003573-84-9

6-methoxy-3-nitro-2-trifluoromethyl-2H-chromene

indole-2,3-dione
91-56-5

indole-2,3-dione

(1S*,3S*,3aS*,4S*,9bR*)-3-[(1H-indol-3-yl)methyl]-8-methoxy-3a-nitro-4-(trifluoromethyl)-2,3,3a,9b-tetrahydro-4H-spiro[chromeno[3,4-c]pyrrole-1,3'-indolin]-2'-one

(1S*,3S*,3aS*,4S*,9bR*)-3-[(1H-indol-3-yl)methyl]-8-methoxy-3a-nitro-4-(trifluoromethyl)-2,3,3a,9b-tetrahydro-4H-spiro[chromeno[3,4-c]pyrrole-1,3'-indolin]-2'-one

Conditions
ConditionsYield
In ethanol at 70℃; for 3h; diastereoselective reaction;91%
2,3-Dichloro-1,4-naphthoquinone
117-80-6

2,3-Dichloro-1,4-naphthoquinone

2-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)-3-(1H-indol-3-yl)propanoic acid

2-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)-3-(1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
Stage #1: Trp With triethylamine; potassium hydroxide In 1,4-dioxane; water at 110℃; for 0.166667h; Microwave irradiation;
Stage #2: 2,3-Dichloro-1,4-naphthoquinone In 1,4-dioxane; water at 110℃; Microwave irradiation;
91%
tryptamine hydochloride
343-94-2

tryptamine hydochloride

Conditions
ConditionsYield
With hydrogenchloride In various solvent(s) for 0.333333h; Heating;90%
With hydrogenchloride In various solvent(s) for 0.333333h; Heating;72%

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