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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality N-Acetyl-L-Tryptophan supplier in China

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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SICHUAN TONGSHENG AMINOACID CO.LTD

Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008, production and quality man

N-Ac-L-Trp

Cas:1218-34-4

Min.Order:100 Gram

Negotiable

Type:Manufacturers

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Shanxi Zorui Biotechnology Co.Ltd.

Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ

99% Purity N-Acetyl-L-Tryptophan Amino Acid Powder CAS 1218-34-4

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

N-Acetyl-L-Tryptophan

Cas:1218-34-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-Acetyl-L-Tryptophan

Cas:1218-34-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

N-Acetyl-L-Tryptophan CAS No 1218-34-4

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 16.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1218-34-4 with best quality

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--1218-34-4--N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

N-Acetyl-L-tryptophanCAS1218-34-4

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $20.0 / 22.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: N-acetyltryptophan Synonyms: Ac-Trp-OH CAS:1218-34-4 MF: C13H14N2O3 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Nutrition Enhancers Transportation:By sea or by air Po

N-acetyltryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

N-acetyl-L-tryptophan manufacturer/supplier

Cas:1218-34-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

N-Acetyl-L-tryptophan 1218-34-4

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Factory Supply Amino Acid N-Acetyl-L-tryptophan raw Powder 99% Purity N-Acetyl-L-tryptophan powder

Cas:1218-34-4

Min.Order:10 Gram

FOB Price: $3.5

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: N-Acetyl-L-tryptophan CAS: 1218-34-4 MF: C13H14N2O3 MW: 246.26 EINECS: 214-935-9 N-Acetyl-L-tryptophan Structure N-Acetyl-L-tryptophan Chemical Properties Melting point 186°C alpha +24.0~+30.0°(20℃/D)(c=

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

N-Acetyl-L-tryptophan CAS:1218-34-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte

N-Acetyl-L-tryptophan CAS:1218-34-4

Cas:1218-34-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory sales N-acetyl-L-tryptophan CAS 1218-34-4

Cas:1218-34-4

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Ac-Trp-OH cas no.1218-34-4 0.98

Cas:1218-34-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

N-ACETYL-L-TRYPTOPHAN

Cas:1218-34-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

NAcetyl-L-Tryptophan

Cas:1218-34-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality N-Acetyl-L-Tryptophan

Cas:1218-34-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

N-Acetyl-L-tryptophan.99%

Cas:1218-34-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

Appearance:powder or granule ( refer to COA) Application:Librium, Valium

Factory Supply Ac-Trp-OH

Cas:1218-34-4

Min.Order:0

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--1218-34-4--N-Acetyl-L-tryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: N-Acetyl-L-Tryptophan CAS No.:1218-34-4 Molecule Formula:C13H14N2O3 Molecule Weight:246.26 Purity: 99.0% Package: 25kg/drum Description:White to off-white crystalline powder Manufacture Standards:Enterprise Standard

High Quality N-Acetyl-L-Tryptophan

Cas:1218-34-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

N-acetyltryptophan methyl ester
2824-57-9, 16108-06-8, 36060-94-3

N-acetyltryptophan methyl ester

A

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With sodium hydroxide; phosphate buffer; pronase EC 3.4.24.4 In tetrahydrofuran Ambient temperature;A 99%
B 99%
With methanol; water; α-chymotrypsin bei pH 7.8;
acetyl chloride
75-36-5

acetyl chloride

L-Tryptophan
73-22-3

L-Tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With sodium hydroxide In acetone at 20℃; pH=> 10;80%
thioacetic acid
507-09-5

thioacetic acid

L-Tryptophan
73-22-3

L-Tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Stage #1: tiolacetic acid With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: L-Tryptophan With 2,4-Dinitrofluorobenzene In N,N-dimethyl-formamide at 20℃; for 3h;
76%
acetic anhydride
108-24-7

acetic anhydride

L-Tryptophan
73-22-3

L-Tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With sodium In water for 2h;73%
Stage #1: L-Tryptophan With sodium hydroxide In water for 0.5h;
Stage #2: acetic anhydride In water at 20℃;
71.8%
With sodium hydroxide; water
N-acetyl-L-tryptophane ethyl ester
2382-80-1

N-acetyl-L-tryptophane ethyl ester

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With ammonium bicarbonate; water In dichloromethane for 21h; α-chymotrypsin;45%
With α-chymotrypsin In phosphate buffer at 25℃; pH=7.8; Kinetics; Further Variations:; Reaction partners; Catalysts; Hydrolysis; Enzymatic reaction;
acetyltryptophan ethylester
42717-06-6

acetyltryptophan ethylester

A

N-AcTrp
1218-34-4

N-AcTrp

B

N-acetyl-D-tryptophan
2280-01-5

N-acetyl-D-tryptophan

C

N-acetyl-D-tryptophan ethyl ester
92520-19-9

N-acetyl-D-tryptophan ethyl ester

Conditions
ConditionsYield
With water In ethanol at 25℃; for 24h; Microbiological reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 40%
tetrachloromethane
56-23-5

tetrachloromethane

acetic anhydride
108-24-7

acetic anhydride

L-Tryptophan
73-22-3

L-Tryptophan

N-AcTrp
1218-34-4

N-AcTrp

N-acetyl-DL-tryptophan
1218-34-4, 87-32-1

N-acetyl-DL-tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With (S)-1-phenyl-ethylamine
With (1S,2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
With (1S,2S)-(+)-thiomicamine
N-acetyl-DL-tryptophan
1218-34-4, 87-32-1

N-acetyl-DL-tryptophan

A

N-AcTrp
1218-34-4

N-AcTrp

B

N-acetyl-D-tryptophan
2280-01-5

N-acetyl-D-tryptophan

Conditions
ConditionsYield
With water bei der Einwirkung einer Amidase;
mit Hilfe von Amidase aus Penicillium vinaceum oder Aspergillus orizae;
mit Hilfe von Pseudomonas;
With water bei der Einwirkung einer Amidase;
(Z)-2-acetamido-3-(3-indolyl)-2-propenoic acid
70082-70-1

(Z)-2-acetamido-3-(3-indolyl)-2-propenoic acid

A

N-AcTrp
1218-34-4

N-AcTrp

B

N-acetyl-D-tryptophan
2280-01-5

N-acetyl-D-tryptophan

Conditions
ConditionsYield
With hydrogen; chloro(1,5-cyclooctadiene)rhodium(I) dimer; (-)-Diop In ethanol at 50℃; for 1.75h; Title compound not separated from byproducts;
With hydrogen; triethylamine; ClO4; (2S,4S)-MOD-BPPM In ethanol at 50℃; under 15200 Torr; for 20h; Title compound not separated from byproducts;
N-acetyl-L-triptophanyl-L-leucine amide
65356-77-6

N-acetyl-L-triptophanyl-L-leucine amide

B

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With pH=7; α-chymotrypsin In water; ethyl acetate Equilibrium constant;
(S)-2-Acetylamino-5-(phenyl-hydrazono)-pentanoic acid methyl ester
85148-76-1

(S)-2-Acetylamino-5-(phenyl-hydrazono)-pentanoic acid methyl ester

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide 1.) reflux, 1 h;; Yield given. Multistep reaction;
4-nitrophenol acetate
830-03-5

4-nitrophenol acetate

L-Tryptophan
73-22-3

L-Tryptophan

A

4-nitro-phenol
100-02-7

4-nitro-phenol

B

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
β‐cyclodextrin In water; dimethyl sulfoxide at 25℃; Rate constant; Mechanism; various conditions;
Nα-acetyl-L-tryptophan-amide
2382-79-8

Nα-acetyl-L-tryptophan-amide

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With Peptidamidase aus dem Flavedo von Orangen; water at 30℃; diff. Peptidamiden; diff. solvents; diff. pH;
With potassium phosphate buffer at 30℃; for 1h; amidase from Erwina carotovora; determination of relative rate of deamination;
With water at 30℃; Peptidamidase aus dem Flavedo von Orangen; Yield given;
With subtilisin-CLEC at 40℃; pH 7.5, phosphate buffer; Yield given;
N-acetyl-L-tryptophan methyl ester
2824-57-9, 16108-06-8, 36060-94-3

N-acetyl-L-tryptophan methyl ester

A

methanol
67-56-1

methanol

B

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With water In dimethyl sulfoxide at 35℃; Rate constant; Equilibrium constant; pH 5.0, pH 7.1; influence of enzyme chymotrypsin; influence of BzPheal=Ala;
(S)-2-Acetylamino-4-cyano-butyric acid methyl ester
75161-70-5

(S)-2-Acetylamino-4-cyano-butyric acid methyl ester

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 88 percent / hydrogen / Raney-Ni deactivated with 3percent Pb / H2O; acetic acid
3: 1.) 0.1 N HCl; 2.) 1 N NaOH / 1.) reflux, 1 h;
View Scheme
methyl 2-acetamido-5-amino-5-oxopentanoate
56159-64-9

methyl 2-acetamido-5-amino-5-oxopentanoate

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 61 percent / p-TsCl / pyridine
2: 88 percent / hydrogen / Raney-Ni deactivated with 3percent Pb / H2O; acetic acid
4: 1.) 0.1 N HCl; 2.) 1 N NaOH / 1.) reflux, 1 h;
View Scheme
(2S,5R)-1-Acetyl-5-hydroxy-pyrrolidine-2-carboxylic acid methyl ester
85148-75-0

(2S,5R)-1-Acetyl-5-hydroxy-pyrrolidine-2-carboxylic acid methyl ester

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 1.) 0.1 N HCl; 2.) 1 N NaOH / 1.) reflux, 1 h;
View Scheme
DL-tryptophan ethyl ester hydrochloride
6519-67-1

DL-tryptophan ethyl ester hydrochloride

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous K2CO3
2: α-chymotrypsin; methanol; water / bei pH 7.8
View Scheme
N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With acetic anhydride In water
Fmoc-Trp-OH
35737-15-6

Fmoc-Trp-OH

acetic acid
64-19-7

acetic acid

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
Stage #1: Fmoc-Trp-OH With dmap In N,N-dimethyl-formamide at 20℃; for 2h; Wang resin; Inert atmosphere;
Stage #2: acetic acid With ammonium bicarbonate In methanol at 20℃; for 3h;
Stage #3: With piperidine; trifluoroacetic acid In N,N-dimethyl-formamide at 20℃; Inert atmosphere;
N-Acetyl-N(1)-nitroso-L-tryptophan
53602-74-7

N-Acetyl-N(1)-nitroso-L-tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With L-Cysteine In aq. phosphate buffer at 37℃; for 1h; pH=7.4; Kinetics;
4-nitrophenol acetate
830-03-5

4-nitrophenol acetate

L-Tryptophan
73-22-3

L-Tryptophan

N-AcTrp
1218-34-4

N-AcTrp

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 24.84℃; pH=8.5 - 9; Kinetics;
benzyl bromide
100-39-0

benzyl bromide

N-AcTrp
1218-34-4

N-AcTrp

Nα-acetyl-(L)-tryptophan benzyl ester

Nα-acetyl-(L)-tryptophan benzyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 23h; Inert atmosphere;99%
N-AcTrp
1218-34-4

N-AcTrp

L-Tryptophan
73-22-3

L-Tryptophan

Conditions
ConditionsYield
With pepsin immobilized on terephthalaldehyde functionalized chitosan magnetic nanoparticle In acetonitrile at 20℃; for 48h; pH=2;98%
With hydrogenchloride; water
With sulfuric acid; water
With Aspergillus oryzae acylase relative rates;
sodium thiocyanide
540-72-7

sodium thiocyanide

acetic anhydride
108-24-7

acetic anhydride

N-AcTrp
1218-34-4

N-AcTrp

(S)-5-((1H-indol-3-yl)methyl)-1-acetyl-2-thioxoimidazolidin-4-one
182002-62-6

(S)-5-((1H-indol-3-yl)methyl)-1-acetyl-2-thioxoimidazolidin-4-one

Conditions
ConditionsYield
In acetic acid at 80 - 85℃; for 0.5h;95%
benzylamine
100-46-9

benzylamine

N-AcTrp
1218-34-4

N-AcTrp

Nα-acetyl-(L)-tryptophan benzyl ester

Nα-acetyl-(L)-tryptophan benzyl ester

Conditions
ConditionsYield
Stage #1: N-AcTrp With N-chlorobenzotriazole; triphenylphosphine In dichloromethane at 0 - 20℃; for 0.25h;
Stage #2: benzylamine With triethylamine at 20℃; for 1.83333h;
95%
trans-dihydroxo (2,3,6,7,12,13,16,17-octaethylporphyrinato)-tin(IV)
29008-64-8

trans-dihydroxo (2,3,6,7,12,13,16,17-octaethylporphyrinato)-tin(IV)

N-AcTrp
1218-34-4

N-AcTrp

trans-di(N-acetyl-L–tryptophanato)[2,3,6,7,12,13,16,17-octa-ethylporphyrinato]-tin(IV)

trans-di(N-acetyl-L–tryptophanato)[2,3,6,7,12,13,16,17-octa-ethylporphyrinato]-tin(IV)

Conditions
ConditionsYield
In chloroform for 12h; Reflux;92%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-AcTrp
1218-34-4

N-AcTrp

(S)-methyl 2-((S)-2-acetamido-3-(1H-indol-3-yl)propanmido)-3-phenyl propanoate

(S)-methyl 2-((S)-2-acetamido-3-(1H-indol-3-yl)propanmido)-3-phenyl propanoate

Conditions
ConditionsYield
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With potassium carbonate In water at 25℃; for 0.166667h;
Stage #2: N-AcTrp With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 12h;
91%
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride In dichloromethane Schlenk technique;
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride In dichloromethane Schlenk technique;
trans-dihydroxo(meso-tetraphenylporphyrinato)tin(IV)
26334-89-4

trans-dihydroxo(meso-tetraphenylporphyrinato)tin(IV)

N-AcTrp
1218-34-4

N-AcTrp

trans-di(N-acetyl-L–tryptophanato)[5,10,15,20-tetraphenyl-porphyrinato]-tin(IV)

trans-di(N-acetyl-L–tryptophanato)[5,10,15,20-tetraphenyl-porphyrinato]-tin(IV)

Conditions
ConditionsYield
In chloroform for 12h; Reflux;91%
ethanol
64-17-5

ethanol

N-AcTrp
1218-34-4

N-AcTrp

N-acetyl-L-tryptophane ethyl ester
2382-80-1

N-acetyl-L-tryptophane ethyl ester

Conditions
ConditionsYield
lipoglycosylated α-chymotrypsin In chloroform at 30℃; or other solvents;90%
α-chymotrypsin In chloroform; water at 30℃; for 24h; phosphate buffer, pH 6.8;86%
α-chymotrypsin at 30℃; for 24h; Equilibrium constant; effect of water concentration, solvent, pH;78%
N-AcTrp
1218-34-4

N-AcTrp

butan-1-ol
71-36-3

butan-1-ol

acetyl-L-tryptophan n-butyl ester
2743-54-6

acetyl-L-tryptophan n-butyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid a) 50 deg C, 0.5 h, b) RT, 4 h;90%
L-valine methylester hydrochloride
6306-52-1

L-valine methylester hydrochloride

N-AcTrp
1218-34-4

N-AcTrp

Ac-Trp-Val-OMe
248589-70-0

Ac-Trp-Val-OMe

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;89%
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: L-valine methylester hydrochloride In dichloromethane Schlenk technique;
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: L-valine methylester hydrochloride In dichloromethane Schlenk technique;
(S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride
2491-18-1

(S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride

N-AcTrp
1218-34-4

N-AcTrp

Ac-Trp-Met-OMe

Ac-Trp-Met-OMe

Conditions
ConditionsYield
Stage #1: (S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride With potassium carbonate In water at 25℃; for 0.166667h;
Stage #2: N-AcTrp With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 12h;
89%
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: (S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride In dichloromethane Schlenk technique;
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: (S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride In dichloromethane Schlenk technique;
O-Methyl (S)-prop-2-ynyl dithiocarbonate
123972-87-2

O-Methyl (S)-prop-2-ynyl dithiocarbonate

N-AcTrp
1218-34-4

N-AcTrp

N-acetyl-L-tryptophan methyl ester
2824-57-9, 16108-06-8, 36060-94-3

N-acetyl-L-tryptophan methyl ester

Conditions
ConditionsYield
In toluene Heating;87%
(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-((R)-1-phenyl-ethyl)-propionamide

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-((R)-1-phenyl-ethyl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;87%
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-((S)-1-phenyl-ethyl)-propionamide

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-((S)-1-phenyl-ethyl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;85%
[(η6-phenylbutyric acid)tris(acetone)ruthenium(II)] triflate

[(η6-phenylbutyric acid)tris(acetone)ruthenium(II)] triflate

N-AcTrp
1218-34-4

N-AcTrp

[(η6-phenylbutyric acid)(η6-N-acetyltriptophane)ruthenium(II)] triflate

[(η6-phenylbutyric acid)(η6-N-acetyltriptophane)ruthenium(II)] triflate

Conditions
ConditionsYield
In trifluoroacetic acid Ar, stirred at 50°C for 3 h; concd., pptd. (diethyl ether), washed (methanol/diethyl ether), dried (vac.); elem. anal.;84%
S-(1-butyn-3-yl)-O-methyl xanthate

S-(1-butyn-3-yl)-O-methyl xanthate

N-AcTrp
1218-34-4

N-AcTrp

N-acetyl-L-tryptophan methyl ester
2824-57-9, 16108-06-8, 36060-94-3

N-acetyl-L-tryptophan methyl ester

Conditions
ConditionsYield
In toluene Heating;81%
(R)-(+)-N,α-dimethylbenzylamine
5933-40-4

(R)-(+)-N,α-dimethylbenzylamine

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-methyl-N-((R)-1-phenyl-ethyl)-propionamide

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-methyl-N-((R)-1-phenyl-ethyl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;80%
[Ru(η(6)-cymene)(acetone)3](CF3SO3)2

[Ru(η(6)-cymene)(acetone)3](CF3SO3)2

N-AcTrp
1218-34-4

N-AcTrp

Ru(CH3C6H4C3H7)(CH3CONHCH(CH2C8H6N)CO2H)(2+)*2CF3SO3(1-)=[Ru(CH3C6H4C3H7)(CH3CONHCH(CH2C8H6N)CO2H)](CF3SO3)2

Ru(CH3C6H4C3H7)(CH3CONHCH(CH2C8H6N)CO2H)(2+)*2CF3SO3(1-)=[Ru(CH3C6H4C3H7)(CH3CONHCH(CH2C8H6N)CO2H)](CF3SO3)2

Conditions
ConditionsYield
In trifluoroacetic acid (argon); stirring (room temp., 4 h); pptn. with Et2O, washing, drying (vac.); elem. anal.;80%
N-AcTrp
1218-34-4

N-AcTrp

N-acetyl-L-tryptophan methyl ester
2824-57-9, 16108-06-8, 36060-94-3

N-acetyl-L-tryptophan methyl ester

Conditions
ConditionsYield
In methanol; diethyl ether at 0℃;79%
Dithiocarbonic acid O-(3-methyl-oxetan-3-ylmethyl) ester S-prop-2-ynyl ester

Dithiocarbonic acid O-(3-methyl-oxetan-3-ylmethyl) ester S-prop-2-ynyl ester

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-3-(1H-indol-3-yl)-propionic acid 3-methyl-oxetan-3-ylmethyl ester

(S)-2-Acetylamino-3-(1H-indol-3-yl)-propionic acid 3-methyl-oxetan-3-ylmethyl ester

Conditions
ConditionsYield
In toluene Heating;79%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

N-AcTrp
1218-34-4

N-AcTrp

(S)-methyl 2-((S)-2-acetamido-3-(1H-indol-3-yl)propanamido)-4-methyl pentanoate

(S)-methyl 2-((S)-2-acetamido-3-(1H-indol-3-yl)propanamido)-4-methyl pentanoate

Conditions
ConditionsYield
Stage #1: methyl (L)-leucinate hydrochloride With potassium carbonate In water at 25℃; for 0.166667h;
Stage #2: N-AcTrp With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 12h;
79%
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: methyl (L)-leucinate hydrochloride In dichloromethane Schlenk technique;
Stage #1: N-AcTrp With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 0.5h; Schlenk technique;
Stage #2: methyl (L)-leucinate hydrochloride In dichloromethane Schlenk technique;
(5-(3-(trifluoromethyl)-3H-diazirin-3-yl)pyridin-2-yl)methanol

(5-(3-(trifluoromethyl)-3H-diazirin-3-yl)pyridin-2-yl)methanol

N-AcTrp
1218-34-4

N-AcTrp

(S)-(5-(3-(trifluoromethyl)-3H-diazirin-3-yl)pyridin-2-yl)methyl 2-acetamido-3-(1H-indol-3-yl)propanoate

(S)-(5-(3-(trifluoromethyl)-3H-diazirin-3-yl)pyridin-2-yl)methyl 2-acetamido-3-(1H-indol-3-yl)propanoate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 21℃; for 16h; Inert atmosphere;77%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 21℃; for 16h; Inert atmosphere;77%
N-methyl-N-[(S)-1-phenylethyl]amine
19131-99-8

N-methyl-N-[(S)-1-phenylethyl]amine

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-methyl-N-((S)-1-phenyl-ethyl)-propionamide

(S)-2-Acetylamino-3-(1H-indol-3-yl)-N-methyl-N-((S)-1-phenyl-ethyl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;76%
2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-N-(2,6-dimethyl-phenyl)-3-(1H-indol-3-yl)-propionamide

(S)-2-Acetylamino-N-(2,6-dimethyl-phenyl)-3-(1H-indol-3-yl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;75%
hexakis-(6-bromo-6-deoxy)-α-cyclodextrin
53784-82-0

hexakis-(6-bromo-6-deoxy)-α-cyclodextrin

N-AcTrp
1218-34-4

N-AcTrp

hexakis-[6-O-(N-acetyl-L-tryptophanyl)]-α-cyclodextrin
1320346-76-6

hexakis-[6-O-(N-acetyl-L-tryptophanyl)]-α-cyclodextrin

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 70 - 80℃; for 12h;72%
2,6-diethylaniline
579-66-8

2,6-diethylaniline

N-AcTrp
1218-34-4

N-AcTrp

(S)-2-Acetylamino-N-(2,6-diethyl-phenyl)-3-(1H-indol-3-yl)-propionamide

(S)-2-Acetylamino-N-(2,6-diethyl-phenyl)-3-(1H-indol-3-yl)-propionamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2 h, 2.) r.t., overnight;70%

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