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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Methyl L-leucinate hydrochloride Manufacturer/High quality/Best price/In stock

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality L-Leucine Methyl Ester Hydrochloride supplier in China

Cas:7517-19-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Methyl L-leucinate hydrochloride 7517-19-3 ISO Manufacturer

Cas:7517-19-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

ProName: Cycloheptane-1,3-Dione CasNo: 1194-18-9 Molecular Formula: C7H10O2 Appearance: Look at the detailed information Application: intermediates DeliveryTime: according to the clients requirement PackAge: according to

L-Leucine Methyl Ester Hydrochloride CAS NO.7517-19-3

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-Leucine methyl ester hydrochloride

Cas:7517-19-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

C7H16ClNO2 Methyl L-leucinate hydrochloride 7517-19-3

Cas:7517-19-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 7517-19-3 with best price

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

L-Leucine methyl ester hydrochloride

Cas:7517-19-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: L-Leucine Methylester HCl Synonyms: L-Leucine methyl ester hydrochloride CAS:7517-19-3 MF: C7H16ClNO2 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Pharmaceutical Interm

L-Leucine Methylester HCl

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

Methyl L-leucinate hydrochloride manufacturer/supplier

Cas:7517-19-3

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methyl L-leucinate hydrochloride 7517-19-3

Cas:7517-19-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply Methyl L-leucinate hydrochloride CAS 7517-19-3

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Methyl L-leucinate hydrochloride with CAS: 7517-19-3

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $12.0 / 20.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Methyl L-leucinate hydrochloride CAS:7517-19-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o

Methyl L-leucinate hydrochloride CAS:7517-19-3

Cas:7517-19-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7517-19-3

Cas:7517-19-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

L-Leucine methyl ester hydrochloride

Cas:7517-19-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL L-LEUCINATE HYDROCHLORIDE 7517-19-3

Cas:7517-19-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality L-Leucine Methyl Ester Hydrochloride

Cas:7517-19-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

High purity L-Leucine Methylester HCl 7517-19-3 in stock immediately delivery good supplierAppearance:Powder Storage:Dry and ventilated Package:according to customers' requirements Application:APIs Transportation:By air(EMS or EUB or FedEx or TNT ect

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

L-Leucine methyl ester hydrochloride

Cas:7517-19-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Reliable Quality Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

L-Leucine,methylester,hydrochloride

Cas:7517-19-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Methyl L-leucinate hydrochloride Basic information Product Name: Methyl L-leucinate hydrochloride Synonyms: Methyl (2S)-2-aMino-4-Methylpentanoate hydrochloride;L-Leucine Methyl ester hydrochloride 98%;L-Leucine Methyl Ester Hydrochloride, 97+

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

High purity Methyl L-leucinate hydrochloride CAS NO.7517-19-3

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Methyl L-leucinate hydrochloride

Cas:7517-19-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

L-Leucine methyl ester hydrochloride

Cas:7517-19-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

L-leucine
61-90-5

L-leucine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
Stage #1: methanol With thionyl chloride for 1h; Cooling with ice;
Stage #2: L-leucine at 20 - 66℃; for 6.5h;
100%
With thionyl chloride at 20℃; for 4h;99%
With thionyl chloride99%
Alloc-Leu-OMe
128369-74-4

Alloc-Leu-OMe

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With triethylsilane; chloroform; palladium on activated charcoal In methanol for 0.0833333h;100%
(S)-2-(2-Aza-bicyclo[2.2.1]hept-5-en-2-yl)-4-methyl-pentanoic acid methyl ester
112018-28-7, 112018-29-8, 126574-84-3

(S)-2-(2-Aza-bicyclo[2.2.1]hept-5-en-2-yl)-4-methyl-pentanoic acid methyl ester

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
Bio-Rad AG 50W-X2 In ethanol at 73℃; for 1h;98%
L-leucine
61-90-5

L-leucine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With thionyl chloride In methanol98%
94%
Multi-step reaction with 2 steps
1: thionyl chloride
View Scheme
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

L-leucine
61-90-5

L-leucine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
In methanol at 20℃; for 24h;98%
methanol
67-56-1

methanol

L-leucine hydrochloride
760-84-9

L-leucine hydrochloride

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0℃;94%
With acetyl chloride at 20℃; for 0.5h;
methanol
67-56-1

methanol

L-leucyl chloride
120335-08-2

L-leucyl chloride

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (S)-2-methoxycarbonylamino-4-methyl-valerate
113089-14-8

methyl (S)-2-methoxycarbonylamino-4-methyl-valerate

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

L-leucine
61-90-5

L-leucine

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 20℃;
(S)-Leu-OMe
2666-93-5

(S)-Leu-OMe

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water
N-benzyloxycarbonyl-L-leucine methyl ester
51021-87-5

N-benzyloxycarbonyl-L-leucine methyl ester

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; acetic acid In water
methanol
67-56-1

methanol

N-tert-butoxycarbonyl-L-leucine
13139-15-6

N-tert-butoxycarbonyl-L-leucine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Conditions
ConditionsYield
With thionyl chloride Inert atmosphere; Reflux;
With thionyl chloride at 20℃; Cooling;
With thionyl chloride at 50℃; for 5h; Inert atmosphere;
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

(S)-2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-4-methyl-pentanoic acid methyl ester
73995-61-6

(S)-2-{[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-4-methyl-pentanoic acid methyl ester

Conditions
ConditionsYield
With sodium carbonate In methanol for 12h; Ambient temperature;100%
With 4 A molecular sieve; titanium tetrachloride; sodium sulfate; triethylamine In dichloromethane at 20℃; for 8h;92%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

(S)-methyl 2-formamido-4-methylpentanoate
54259-27-7

(S)-methyl 2-formamido-4-methylpentanoate

Conditions
ConditionsYield
at 95℃; for 1h;100%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

N-benzyloxycarbonyl-L-leucine methyl ester
51021-87-5

N-benzyloxycarbonyl-L-leucine methyl ester

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane for 4h; Ambient temperature;100%
With triethylamine In dichloromethane at 20℃;80%
With sodium hydrogencarbonate In diethyl ether; water at 0 - 20℃; for 3h;63%
Stage #1: methyl (L)-leucinate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.25h; Inert atmosphere;
Stage #2: benzyl chloroformate In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere;
With sodium carbonate In water at 20℃; for 16h;
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

phenyl chloroformate
1885-14-9

phenyl chloroformate

N-benzyloxycarbonyl-L-leucine methyl ester
51021-87-5

N-benzyloxycarbonyl-L-leucine methyl ester

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water100%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

sodium carbonate
497-19-8

sodium carbonate

phenyl chloroformate
1885-14-9

phenyl chloroformate

N-benzyloxycarbonyl-L-leucine methyl ester
51021-87-5

N-benzyloxycarbonyl-L-leucine methyl ester

Conditions
ConditionsYield
In 1,4-dioxane; water100%
C10H12O4
1035609-27-8

C10H12O4

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester
1035609-29-0

N-[(2S,3R)-2,3-dihydroxy-4-phenylbutanoyl]-L-leucine methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 1.5h;100%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Nα,Nβ-bis(t-butoxycarbonyl)-L-α,β-diaminopropionic acid
88971-40-8

Nα,Nβ-bis(t-butoxycarbonyl)-L-α,β-diaminopropionic acid

N,N'-di-Boc-2,3-L-Dap-L-Leu-OMe
1156494-69-7

N,N'-di-Boc-2,3-L-Dap-L-Leu-OMe

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃;100%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

4-Phenylbutyric acid
1821-12-1

4-Phenylbutyric acid

(S)-methyl 4-methyl-2-(4-phenylbutanamido)pentanoate
1170728-22-9

(S)-methyl 4-methyl-2-(4-phenylbutanamido)pentanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 20℃; for 5h; Cooling with ice;100%
bromobenzene
108-86-1

bromobenzene

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

A

biphenyl
92-52-4

biphenyl

B

(S)-2-amino-1,1-diphenyl-4-methylpentan-1-ol
78603-97-1

(S)-2-amino-1,1-diphenyl-4-methylpentan-1-ol

Conditions
ConditionsYield
Stage #1: bromobenzene With magnesium In diethyl ether at 40℃; Inert atmosphere;
Stage #2: methyl (L)-leucinate hydrochloride In diethyl ether at 0 - 20℃; for 15.5h;
A n/a
B 100%
(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(((tert-butoxycarbonyl)amino)methyl)phenyl)propanoic acid
1394024-95-3

(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(((tert-butoxycarbonyl)amino)methyl)phenyl)propanoic acid

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

Cbz-Phe(4-CH2NHBoc)-Leu-OMe
1421639-93-1

Cbz-Phe(4-CH2NHBoc)-Leu-OMe

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane for 2h;100%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

pyromellitic acid monoanhydride
7487-10-7

pyromellitic acid monoanhydride

C17H17NO8

C17H17NO8

Conditions
ConditionsYield
Stage #1: methyl (L)-leucinate hydrochloride; pyromellitic acid monoanhydride With N,N-dimethyl acetamide; triethylamine at 20℃; for 22h; Inert atmosphere;
Stage #2: With acetic anhydride at 80℃; for 7h; Inert atmosphere;
100%
4-nitrophenyl ((αR)-6-((3-carbamoylpyridin-2-yl)oxy )spiro[3.3]heptan-2-yl)carbamate

4-nitrophenyl ((αR)-6-((3-carbamoylpyridin-2-yl)oxy )spiro[3.3]heptan-2-yl)carbamate

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (((aR)-6-((3-carbamoylpyridin-2-yl)oxy)spiro[3.3]heptan-2-yl)carbamoyl)-L-leucinate

methyl (((aR)-6-((3-carbamoylpyridin-2-yl)oxy)spiro[3.3]heptan-2-yl)carbamoyl)-L-leucinate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20 - 50℃; for 14h;100%
C23H41N3O6

C23H41N3O6

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

C30H54N4O7

C30H54N4O7

Conditions
ConditionsYield
Stage #1: C23H41N3O6 With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 0.5h;
Stage #2: methyl (L)-leucinate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;
100%
(S)-N-(tert-butoxycarbonyl)serine
3262-72-4

(S)-N-(tert-butoxycarbonyl)serine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropanoylamino)-4-methylpentanoic acid methyl ester
85328-90-1

(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropanoylamino)-4-methylpentanoic acid methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0 - 20℃; pH=8 - 9;99%
Stage #1: methyl (L)-leucinate hydrochloride With sodium carbonate In dichloromethane; water at 20℃; for 0.0833333h;
Stage #2: (S)-N-(tert-butoxycarbonyl)serine With C12H6B2Br4O3 In 1,2-dichloro-ethane at 90℃; for 18h; chemoselective reaction;
99%
With 4-methyl-morpholine; dicyclohexyl-carbodiimide In acetonitrile 0 deg C, 2 h; room temp., overnight;70%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

benzoyl chloride
98-88-4

benzoyl chloride

N-benzoyl-L-leucine methyl ester
3005-60-5

N-benzoyl-L-leucine methyl ester

Conditions
ConditionsYield
With potassium carbonate In chloroform for 3h; Heating;99%
With N-ethyl-N,N-diisopropylamine In dichloromethane; ethyl acetate at 20℃;61%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h;61%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

benzaldehyde
100-52-7

benzaldehyde

methyl (S)-2-(benzylideneamino)-4-methylpentanoate
75691-28-0

methyl (S)-2-(benzylideneamino)-4-methylpentanoate

Conditions
ConditionsYield
With triethylamine In chloroform at 0 - 20℃; for 24h; Inert atmosphere; Sealed tube;99%
Stage #1: methyl (L)-leucinate hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.25h; Inert atmosphere;
Stage #2: benzaldehyde In dichloromethane at 20℃; Inert atmosphere;
98%
With triethylamine In dichloromethane for 24h; Ambient temperature;
BOC-glycine
4530-20-5

BOC-glycine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

(S)-methyl 2-(2-((tert-butoxycarbonyl)amino)acetamido)-4-methylpentanoate
7535-69-5

(S)-methyl 2-(2-((tert-butoxycarbonyl)amino)acetamido)-4-methylpentanoate

Conditions
ConditionsYield
Stage #1: BOC-glycine With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 1h; Inert atmosphere;
Stage #2: methyl (L)-leucinate hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;
99%
Stage #1: BOC-glycine With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: methyl (L)-leucinate hydrochloride In dichloromethane at 20℃; for 1h; Inert atmosphere;
98%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;97%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

(S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate
203873-66-9

(S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 12h; Inert atmosphere;99%
With triethylamine In dichloromethane at 20℃; for 0.5h;75%
With pyridine In dichloromethane at 20℃;
Stage #1: methyl (L)-leucinate hydrochloride; 4-Nitrobenzenesulfonyl chloride In dichloromethane at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: With triethylamine In dichloromethane at 20℃; for 11h; Inert atmosphere;
Stage #1: methyl (L)-leucinate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 0.166667h;
Stage #2: 4-Nitrobenzenesulfonyl chloride In dichloromethane at 0℃;
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

N-(L-leucine methyl ester)-3β-acetyl-11-oxo-olean-12-en-18β-H-30-amide

N-(L-leucine methyl ester)-3β-acetyl-11-oxo-olean-12-en-18β-H-30-amide

Conditions
ConditionsYield
Stage #1: acetoxolone With oxalyl dichloride In dichloromethane at 20℃; for 2h;
Stage #2: methyl (L)-leucinate hydrochloride With triethylamine In dichloromethane at 20℃;
99%
methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

N-tert-butoxycarbonyl-3-(2-naphthyl)-L-alanine
56583-58-5, 76985-10-9, 58438-04-3

N-tert-butoxycarbonyl-3-(2-naphthyl)-L-alanine

N-tert-butoxycarbonyl-L-tryptophan-L-leucine methylester
256368-03-3

N-tert-butoxycarbonyl-L-tryptophan-L-leucine methylester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃;99%
N-α-benzyloxycarbonyl-DL-tyrosine
5618-98-4

N-α-benzyloxycarbonyl-DL-tyrosine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

(S)-2-[(S)-2-benzyloxycarbonylamino-3-(4-hydroxyphenyl)propionylamino]-4-methylpentanoic acid methyl ester

(S)-2-[(S)-2-benzyloxycarbonylamino-3-(4-hydroxyphenyl)propionylamino]-4-methylpentanoic acid methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine; DMT*brucine tetrafluoroborate; brucine In acetonitrile at 0 - 20℃; optical yield given as %ee; enantioselective reaction;99%
(S)-N-(benzyloxycarbonyl)valine
1149-26-4

(S)-N-(benzyloxycarbonyl)valine

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-4-methylpentanoate
4817-93-0

(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-4-methylpentanoate

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 12h;99%
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0 - 20℃; for 12h;69%
With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 0 - 20℃;69%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

piperazine-1-carboxylic acid (4-methoxy-phenyl)-amide

piperazine-1-carboxylic acid (4-methoxy-phenyl)-amide

methyl (4-((4-methoxyphenyl)carbamoyl)piperazine-1-carbonyl)-L-leucinate

methyl (4-((4-methoxyphenyl)carbamoyl)piperazine-1-carbonyl)-L-leucinate

Conditions
ConditionsYield
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine In dichloromethane; water at 0 - 20℃; for 3h;99%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

C13H19N3O2

C13H19N3O2

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (4-(3-(4-methoxyphenyl)ureido)piperidine-1-carbonyl)-L-leucinate

methyl (4-(3-(4-methoxyphenyl)ureido)piperidine-1-carbonyl)-L-leucinate

Conditions
ConditionsYield
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine In dichloromethane; water at 0 - 20℃; for 3h;99%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

N-(4-Fluorophenyl)piperidine-4-carboxamide

N-(4-Fluorophenyl)piperidine-4-carboxamide

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (4-((4-fluorophenyl)carbamoyl)piperidine-1-carbonyl)-L-leucinate

methyl (4-((4-fluorophenyl)carbamoyl)piperidine-1-carbonyl)-L-leucinate

Conditions
ConditionsYield
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine In dichloromethane; water at 0 - 20℃; for 3h;99%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

C9H13N3O2

C9H13N3O2

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (4-(isoxazol-3-ylcarbamoyl)piperidine-1-carbonyl)-L-leucinate

methyl (4-(isoxazol-3-ylcarbamoyl)piperidine-1-carbonyl)-L-leucinate

Conditions
ConditionsYield
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine In dichloromethane; water at 0 - 20℃; for 3h;99%
4-(3-pyridylcarbamoyl)piperidine
779999-14-3

4-(3-pyridylcarbamoyl)piperidine

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (4-(pyridin-3-ylcarbamoyl)piperidine-1-carbonyl)-L-leucinate

methyl (4-(pyridin-3-ylcarbamoyl)piperidine-1-carbonyl)-L-leucinate

Conditions
ConditionsYield
With sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine In dichloromethane; water at 0 - 20℃; for 3h;99%
C13H15ClN2O3
147636-50-8

C13H15ClN2O3

methyl (L)-leucinate hydrochloride
7517-19-3

methyl (L)-leucinate hydrochloride

methyl (1-((4-chlorophenyl)carbamoyl)piperidine-4-carbonyl)-L-leucinate

methyl (1-((4-chlorophenyl)carbamoyl)piperidine-4-carbonyl)-L-leucinate

Conditions
ConditionsYield
Stage #1: C13H15ClN2O3 With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 0.5h;
Stage #2: methyl (L)-leucinate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 3h;
99%

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