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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N-(2,3-Epoxypropyl)phthalimide Manufacturer/High quality/Best price/In stock

Cas:5455-98-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality N-(2,3-Epoxypropyl)-O-Phthalimide supplier in China

Cas:5455-98-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-(Oxiranylmethyl)-phthalimide

Cas:5455-98-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

N-(2,3-EPOXYPROPYL)PHTHALIMIDE

Cas:5455-98-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5455-98-1 with competitive price

Cas:5455-98-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Isoindole-1,3(2H)-dione,2-(2-oxiranylmethyl)- 5455-98-1

Cas:5455-98-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, N-(2,3-EPOXYPROPYL)PHTHALIMIDE CAS:5455-98-1

Cas:5455-98-1

Min.Order:1 Kilogram

FOB Price: $27.0 / 32.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

N-(2,3-EPOXYPROPYL)PHTHALIMIDE CAS:5455-98-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

N-(2,3-EPOXYPROPYL)PHTHALIMIDE CAS:5455-98-1

Cas:5455-98-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Isoindole-1,3(2H)-dione,2-(2-oxiranylmethyl)-

Cas:5455-98-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:5455-98-1

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

N-(2,3-epoxypropyl)-o-phthalimide

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply N-(2,3-epoxypropyl)phthalimide

Cas:5455-98-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

N-(2,3-Epoxypropyl)phthalimide

Cas:5455-98-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Isoindole-1,3(2H)-dione,2-(2-oxiranylmethyl)-

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

N-(2,3-EPOXYPROPYL)PHTHALIMIDE

Cas:5455-98-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality N-(2,3-Epoxypropyl)-O-Phthalimide

Cas:5455-98-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: N-(2,3-Epoxypropyl)-O-Phthalimide CAS No.:5455-98-1 Molecule Formula:C11H9NO3 Molecule Weight:203.19 Purity: 80.0% Package: 25kg/drum Description:White or almost white crystalline powder Manufacture Standards:Enterprise

High Quality N-(2,3-Epoxypropyl)-O-Phthalimide

Cas:5455-98-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

N-(2,3-EPOXYPROPYL)PHTHALIMIDE,5455-98-1

Cas:5455-98-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

N-(2,3-EPOXYPROPYL)PHTHALIMIDE

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

N-(2,3-Epoxypropyl)phthalimide5455-98-1 CAS NO.5455-98-1

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

N-(2,3-epoxypropyl)phthalimide

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

N-(2,3-epoxypropyl)phthalimide

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-(Oxiran-2-ylMethyl)isoindoline-1,3-dione

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

N-(2,3-Epoxypropyl)-O-Phthalimide

Cas:5455-98-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec N-Glycidyl Phthalimide 10g

Cas:5455-98-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

N-(2,3-EPOXYPROPYL)PHTHALIMIDE

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

N-(2,3-Epoxypropyl)-O-Phthalimide

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

N-(2,3-epoxypropyl)phthalimide

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

N-(2,3-EPOXYPROPYL)PHTHALIMIDE

Cas:5455-98-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

3-phthalimido-1-propene
5428-09-1

3-phthalimido-1-propene

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane99%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 72h;92%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 16h;
2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
19667-37-9, 34839-11-7, 148857-42-5, 148857-44-7

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
With potassium fluoride supported on Celite In acetonitrile for 0.5h; Reflux; regioselective reaction;98%
With potassium carbonate In toluene Reflux;
potassium phtalimide
1074-82-4

potassium phtalimide

epichlorohydrin
106-89-8

epichlorohydrin

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
for 8h; Reflux;95%
In N,N-dimethyl-formamide at 20℃; for 10h;90%
at 120℃; for 5h;80%
phthalimide
136918-14-4

phthalimide

epichlorohydrin
106-89-8

epichlorohydrin

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
With potassium carbonate at 120℃; for 5h;89%
With potassium fluoride; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 85℃; for 6h;87%
Stage #1: phthalimide With potassium hydroxide In ethanol; water at 75 - 85℃;
Stage #2: epichlorohydrin at 120℃;
68.54%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 15℃; for 12h; Inert atmosphere;36.6%
phthalimide
136918-14-4

phthalimide

epichlorohydrin
106-89-8

epichlorohydrin

A

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

B

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
19667-37-9, 34839-11-7, 148857-42-5, 148857-44-7

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With potassium fluoride on basic alumina In 2-methyltetrahydrofuran for 3h; Inert atmosphere; Reflux; chemoselective reaction;A 12%
B 86%
With aluminum oxide In 1-methyl-pyrrolidin-2-one at 64 - 68℃;
phthalimide
136918-14-4

phthalimide

oxiranyl-methanol
556-52-5

oxiranyl-methanol

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran Mitsunobu reaction;75%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran for 18h; Ambient temperature;72%
potassium phtalimide
1074-82-4

potassium phtalimide

1,2-Epoxy-3-bromopropane
3132-64-7

1,2-Epoxy-3-bromopropane

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
In 1,2-dimethoxyethane at 120℃; for 3h;51%
potassium phtalimide
1074-82-4

potassium phtalimide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80.2 percent / dimethylformamide / 50 °C
2: 92 percent / m-chloroperbenzoic acid / CH2Cl2 / 72 h
View Scheme
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide / 16 h / 80 °C
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C
View Scheme
potassium phtalimide
1074-82-4

potassium phtalimide

o-xylylene dichloride

o-xylylene dichloride

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 82 percent / 18-crown-6 / toluene
2: 99 percent / mCPBA / CH2Cl2
View Scheme
glycidyl p-toluenesulfonate
118712-54-2

glycidyl p-toluenesulfonate

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Reaxys ID: 20826319

Reaxys ID: 20826319

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

phthalimide
136918-14-4

phthalimide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
19667-37-9, 34839-11-7, 148857-42-5, 148857-44-7

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With hydrogenchloride In chloroform; water at 0℃; for 0.5h;100%
With hydrogenchloride In chloroform; water at 0℃; for 0.5h;100%
With hydrogenchloride; water In chloroform at 0℃; for 0.5h; regioselective reaction;100%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(2-hydroxy-3-iodopropyl)-1H-isoindole-1,3(2H)-dione

2-(2-hydroxy-3-iodopropyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With water; hydrogen iodide In chloroform at 0℃; for 1h; regioselective reaction;100%
Stage #1: 2-oxiranylmethylisoindole-1,3-dione With diiodomethane In 2-methyltetrahydrofuran at -78℃; for 0.0333333h;
Stage #2: With methyllithium In 2-methyltetrahydrofuran; diethyl ether at -78℃; for 1h; Reagent/catalyst;
91%
With chloroform; hydrogen iodide
With water; hydrogen iodide
1,1,1-tri(hydroxymethyl)propane
77-99-6

1,1,1-tri(hydroxymethyl)propane

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

oxiranyl-methanol
556-52-5

oxiranyl-methanol

C72H107N3O34

C72H107N3O34

Conditions
ConditionsYield
Stage #1: 1,1,1-tri(hydroxymethyl)propane With potassium tert-butylate In tetrahydrofuran at 120℃; for 18h; Inert atmosphere;
Stage #2: oxiranyl-methanol In tetrahydrofuran at 120℃; for 0.5h; Inert atmosphere;
Stage #3: 2-oxiranylmethylisoindole-1,3-dione In tetrahydrofuran at 120℃; Inert atmosphere;
100%
1-(2,3-dichlorophenyl)-piperazine hydrochloride

1-(2,3-dichlorophenyl)-piperazine hydrochloride

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]isoindoline-1,3-dione
1220950-99-1

2-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]isoindoline-1,3-dione

Conditions
ConditionsYield
With triethylamine In isopropyl alcohol at 100℃; for 1.5h; Microwave irradiation;99%
With triethylamine In tetrahydrofuran at 20 - 80℃; Inert atmosphere;
With triethylamine In tetrahydrofuran at 80℃; Inert atmosphere;
With triethylamine In tetrahydrofuran at 20 - 80℃; Inert atmosphere;13 g
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

N-(tert-butoxycarbonyl)-1,4-phenylenediamine
71026-66-9

N-(tert-butoxycarbonyl)-1,4-phenylenediamine

C22H25N3O5

C22H25N3O5

Conditions
ConditionsYield
In isopropyl alcohol for 5h; Reflux;99%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(3-bromo-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
6284-27-1

2-(3-bromo-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With water; hydrogen bromide In chloroform at 0℃; for 0.5h; regioselective reaction;98%
Stage #1: 2-oxiranylmethylisoindole-1,3-dione With iodobromomethane In 2-methyltetrahydrofuran at -78℃; for 0.0333333h;
Stage #2: With methyllithium In 2-methyltetrahydrofuran; diethyl ether at -78℃; for 1h;
89%
With chloroform; hydrogen bromide
With water; hydrogen bromide
With hydrogen bromide In chloroform at 0℃; for 16h;
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

benzoic acid
65-85-0

benzoic acid

N-<3-(benzoyloxy)-2-hydroxypropyl>phthalimide
130277-94-0

N-<3-(benzoyloxy)-2-hydroxypropyl>phthalimide

Conditions
ConditionsYield
With sodium benzoate In N,N-dimethyl-formamide for 3h; Heating;98%
piperidine
110-89-4

piperidine

carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl piperidine-1-carbodithioate

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl piperidine-1-carbodithioate

Conditions
ConditionsYield
In water at 20℃; for 8h; regioselective reaction;98%
carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

diethylamine
109-89-7

diethylamine

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl diethylcarbamodithioate

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl diethylcarbamodithioate

Conditions
ConditionsYield
In water at 20℃; for 8h; regioselective reaction;98%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(3-azido-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
200483-38-1

2-(3-azido-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With sodium azide; water; acetic acid at 0 - 30℃; for 6h; regioselective reaction;97%
With lithium azidohydridodiisobutylaluminate In tetrahydrofuran for 2h; Ambient temperature;76%
With sodium azide; ammonium chloride In ethanol; water at 0 - 20℃;74.2%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

dibenzylamine
103-49-1

dibenzylamine

2-(3-(dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione
170799-33-4

2-(3-(dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione

Conditions
ConditionsYield
at 80℃; for 20h;95%
Stage #1: 2-oxiranylmethylisoindole-1,3-dione; dibenzylamine at 80℃;
Stage #2: With ethanol at 20℃;
4.5 g
1-(2,3-dichlorophenyl)-piperazine hydrochloride

1-(2,3-dichlorophenyl)-piperazine hydrochloride

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

1-amino-3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propan-2-ol
1220950-98-0

1-amino-3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propan-2-ol

Conditions
ConditionsYield
Stage #1: 1-(2,3-dichlorophenyl)-piperazine hydrochloride; 2-oxiranylmethylisoindole-1,3-dione With triethylamine In tetrahydrofuran at 80℃;
Stage #2: With water In tetrahydrofuran
Stage #3: With hydrazine hydrate In ethanol at 80℃; for 2h;
95%
pyrrolidine
123-75-1

pyrrolidine

carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl pyrrolidine-1-carbodithioate

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl pyrrolidine-1-carbodithioate

Conditions
ConditionsYield
In water at 20℃; for 8h; regioselective reaction;95%
carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-((2-thioxo-1,3-dithiolan-4-yl)methyl)isoindoline-1,3-dione

2-((2-thioxo-1,3-dithiolan-4-yl)methyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolim bromide; potassium hydroxide; lithium bromide In neat (no solvent) at 70℃; for 24h; chemoselective reaction;95%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

1-hydroxy-3-phthalimidopropan-2-one
35750-04-0

1-hydroxy-3-phthalimidopropan-2-one

Conditions
ConditionsYield
With ammonium heptamolybdate; dihydrogen peroxide In tetrahydrofuran at 20℃; for 0.75h; Oxidation;94%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(4-fluoro-benzyl-amino)-ethanol
22116-33-2

2-(4-fluoro-benzyl-amino)-ethanol

4-(4-fluorobenzyl)-2-aminomethylmorpholine hydrochloride

4-(4-fluorobenzyl)-2-aminomethylmorpholine hydrochloride

Conditions
ConditionsYield
Stage #1: 2-oxiranylmethylisoindole-1,3-dione; 2-(4-fluoro-benzyl-amino)-ethanol at 70 - 80℃; for 3h;
Stage #2: With sulfuric acid at 70 - 145℃; for 2.5h;
Stage #3: With hydrogenchloride In ethanol; water for 1.5h;
92.7%
morpholine
110-91-8

morpholine

carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl morpholine-4-carbodithioate

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl morpholine-4-carbodithioate

Conditions
ConditionsYield
In water at 20℃; for 8h; regioselective reaction;92%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

phenyl isocyanate
103-71-9

phenyl isocyanate

3-phenyl-5-(phthalimidomethyl)oxazolidin-2-one

3-phenyl-5-(phthalimidomethyl)oxazolidin-2-one

Conditions
ConditionsYield
With triethylammonium iodide In neat (no solvent) at 100℃; for 1h; Green chemistry;92%
sodium cyanide
773837-37-9

sodium cyanide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-hydroxybutanenitrile
13635-07-9, 132155-85-2, 132203-23-7

4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-hydroxybutanenitrile

Conditions
ConditionsYield
With water; acetic acid In ethanol at 0 - 20℃; for 5h; regioselective reaction;91%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

thiophenol
108-98-5

thiophenol

2-[2-hydroxy-3-(phenylthio)propyl]-1H-isoindole-1,3(2H)-dione
1396010-01-7

2-[2-hydroxy-3-(phenylthio)propyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With zinc perchlorate In chloroform at 20℃; for 6h; regioselective reaction;91%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

D-phenylalanine-L-alanine methylester
80870-39-9

D-phenylalanine-L-alanine methylester

2-{2-[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-2-hydroxypropylamino]-3-phenylpropionylamino}propionic acid methyl ester
1166862-28-7

2-{2-[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-2-hydroxypropylamino]-3-phenylpropionylamino}propionic acid methyl ester

Conditions
ConditionsYield
In trifluoroethanol for 3.5h; Reflux;90%
hexamethylene imine
111-49-9

hexamethylene imine

carbon disulfide
75-15-0

carbon disulfide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl azepane-1-carbodithioate

3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropyl azepane-1-carbodithioate

Conditions
ConditionsYield
In water at 20℃; for 8h; regioselective reaction;90%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(4-fluoro-benzyl-amino)-ethanol
22116-33-2

2-(4-fluoro-benzyl-amino)-ethanol

4-(4-fluorobenzyl)-2-aminomethylmorpholine sulfate

4-(4-fluorobenzyl)-2-aminomethylmorpholine sulfate

Conditions
ConditionsYield
Stage #1: 2-oxiranylmethylisoindole-1,3-dione; 2-(4-fluoro-benzyl-amino)-ethanol at 70 - 80℃; for 3h;
Stage #2: With sulfuric acid at 70 - 145℃; for 2.5h;
Stage #3: With sulfuric acid In ethanol for 2h;
89.88%
ortho-methylphenyl iodide
615-37-2

ortho-methylphenyl iodide

2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

tris-iso-propylsilyl acetylene
89343-06-6

tris-iso-propylsilyl acetylene

2-(2-hydroxy-3-(3-methyl-2-((triisopropylsilyl)ethynyl)phenyl)propyl)isoindoline-1,3-dione

2-(2-hydroxy-3-(3-methyl-2-((triisopropylsilyl)ethynyl)phenyl)propyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; norborn-2-ene; potassium acetate; palladium diacetate; XPhos at 60℃; for 24h; Glovebox; Inert atmosphere; Sealed tube; regioselective reaction;89%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(4-fluoro-benzyl-amino)-ethanol
22116-33-2

2-(4-fluoro-benzyl-amino)-ethanol

C12H17FN2O4S

C12H17FN2O4S

Conditions
ConditionsYield
Stage #1: 2-oxiranylmethylisoindole-1,3-dione; 2-(4-fluoro-benzyl-amino)-ethanol at 70 - 80℃; for 3h;
Stage #2: With sulfuric acid at 70 - 145℃; for 2.5h;
Stage #3: With sulfuric acid In ethanol for 1.5h;
88.53%
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

2-(4-fluoro-benzyl-amino)-ethanol
22116-33-2

2-(4-fluoro-benzyl-amino)-ethanol

4-(4-fluorobenzyl)-2-aminomethylmorpholine phosphate

4-(4-fluorobenzyl)-2-aminomethylmorpholine phosphate

Conditions
ConditionsYield
Stage #1: 2-oxiranylmethylisoindole-1,3-dione; 2-(4-fluoro-benzyl-amino)-ethanol at 70 - 80℃; for 3h;
Stage #2: With sulfuric acid at 70 - 145℃; for 2.5h;
Stage #3: With phosphoric acid In ethanol for 1.5h;
88.27%
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