GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryItems Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------
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inquiryUnique advantages for Enrofloxacin Cas 93106-60-6 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Yellow Powder Storage:-20°C Freezer Package:1kg/foil bag, 25kg/
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Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ
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inquiryCompetitive Price High Quality Fast Delivery custom-made Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble me
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryName: Enrofloxacin Synonyms: 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid CAS:93106-60-6 MF: C19H22FN3O3 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Packag
We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED
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inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
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inquiry1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermediate
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inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
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inquiryEnrofloxacin CAS:93106-60-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
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inquiryAs a leading manufacturer and supplier of chemicals in China, JudaChem not only supply popular chemicals, but also JudaChem's R&D center offer custom synthesis services. JudaChem can provide different quantities of custom synt
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inquiryEnrofloxacine CAS: 93106-60-6 Specification:CVP2010 Stock:Fresh Application:93106-60-6
Product Name: Enrofloxacin Synonyms: 1,4-dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinoli;ROFLOXACIN BASE;enrofloxacin Baytril;Enorofloxacin hydrochloride;ENROFLOX
4-ethylpiperazine
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
enrofloxacin
Conditions | Yield |
---|---|
With nano iron oxide on ZrO2 coated sulfonic acid In water for 0.316667h; Solvent; Temperature; Reagent/catalyst; Reflux; | 97% |
at 150℃; for 0.416667h; Microwave irradiation; | 93% |
With aluminum tri-bromide In ethanol at 75℃; for 4h; Reagent/catalyst; Solvent; Temperature; | 92% |
4-ethylpiperazine
enrofloxacin
Conditions | Yield |
---|---|
With aluminum (III) chloride In i-Amyl alcohol at 140℃; for 8h; Temperature; | 91.8% |
ditrimethylsilyl N-cyclopropyl-3-(4-ethyl-1-piperazinyl)anilinomethylenemalonate
enrofloxacin
Conditions | Yield |
---|---|
90% |
4-ethylpiperazine
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
B
enrofloxacin
Conditions | Yield |
---|---|
In water for 13h; Heating; | A n/a B 89% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; potassium iodide In water; acetonitrile at 20℃; for 12h; | 70% |
4-ethylpiperazine
ethyl 2,4,5-trifluorobenzoylacetate
N,N-dimethyl-formamide dimethyl acetal
Cyclopropylamine
enrofloxacin
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
ethyl 2,4-dichloro-5-fluoro-benzoyl-acetate
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: acetic anhydride / 2 h / Heating 2: 92 percent / ethanol / 1 h / Ambient temperature 3: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 4: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 5: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
3-Cyclopropylamino-2-(2,4-dichlor-5-fluorbenzoyl)acrylsaeure-ethylester
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 2: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 3: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
ethyl 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylate
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 2: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
2,4-dichloro-5-fluorobenzoyl chloride
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 62 percent / pyridine / dioxane / 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C. 2: 85 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 3: 92 percent / conc. H2SO4 / H2O; acetic acid / 1.5 h / Heating 4: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme | |
Multi-step reaction with 7 steps 1: Mg/ethanol, CCl4 / ethanol; toluene / 1.) 0 to -5 deg C, 2.) 12 h, room temperature 2: p-toluenesulfonic acid / H2O / 5 h / Heating 3: acetic anhydride / 2 h / Heating 4: 92 percent / ethanol / 1 h / Ambient temperature 5: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 6: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 7: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: tributyl-amine / 1 h / 70 °C 1.2: 15 °C / 1520.1 Torr 2.1: cesium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene / 125 - 130 °C 2.2: 8 h / 85 °C View Scheme |
3-Cyclopropylamino-2-(2,4-dichlor-5-fluorbenzoyl)acrylsaeure-methylester
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 85 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 2: 92 percent / conc. H2SO4 / H2O; acetic acid / 1.5 h / Heating 3: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid methyl ester
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 92 percent / conc. H2SO4 / H2O; acetic acid / 1.5 h / Heating 2: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
diethyl 2,4-dichloro-5-fluoro-benzoyl-malonate
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: p-toluenesulfonic acid / H2O / 5 h / Heating 2: acetic anhydride / 2 h / Heating 3: 92 percent / ethanol / 1 h / Ambient temperature 4: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 5: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 6: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
3-(Cyclopropylamino)acrylsaeure-methylester
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 62 percent / pyridine / dioxane / 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C. 2: 85 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 3: 92 percent / conc. H2SO4 / H2O; acetic acid / 1.5 h / Heating 4: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
2,4-dichloro-alpha(elhoxymethlene)-5-fluoro-beta-oxo-benzene propanoic acid ethyl ester
enrofloxacin
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 92 percent / ethanol / 1 h / Ambient temperature 2: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 3: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 4: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
4-ethylpiperazine
3-Cyclopropylamino-2-(2,4-dichlor-5-fluorbenzoyl)acrylsaeure-ethylester
enrofloxacin
Conditions | Yield |
---|---|
Stage #1: 3-Cyclopropylamino-2-(2,4-dichlor-5-fluorbenzoyl)acrylsaeure-ethylester With cesium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene at 125 - 130℃; Stage #2: 4-ethylpiperazine With aluminum (III) chloride In ethanol at 85℃; for 8h; Solvent; Reagent/catalyst; Temperature; | 48.7 g |
enrofloxacin
1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-quinolinoyl chloride
Conditions | Yield |
---|---|
With thionyl chloride for 10h; Heating; | 95.1% |
With thionyl chloride at 75℃; for 10h; | |
With thionyl chloride at 70℃; |
Conditions | Yield |
---|---|
With sodium hydroxide In methanol at 20℃; for 2h; | 88% |
enrofloxacin
1,1'-carbonyldiimidazole
Conditions | Yield |
---|---|
In acetonitrile Solvent; Reflux; | 86.4% |
enrofloxacin
Conditions | Yield |
---|---|
With water; calcium hydroxide In methanol at 40℃; for 8h; Temperature; Solvent; | 85% |
1,10-Phenanthroline
enrofloxacin
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide In ethanol for 2h; pH=7; | 85% |
1,10-Phenanthroline
enrofloxacin
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide In ethanol for 2h; pH=7; | 82% |
8-quinolinol
enrofloxacin
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide In ethanol for 2h; pH=7; Reflux; | 80% |
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide In ethanol for 1h; pH=7; Reflux; | 80% |
Conditions | Yield |
---|---|
With hydrogenchloride; potassium hydroxide In ethanol for 1h; pH=7; Reflux; | 78% |
Conditions | Yield |
---|---|
Stage #1: vanadium(V) oxychloride; enrofloxacin With sodium hydroxide In ethanol at 20℃; for 1h; Stage #2: o-toluidine In ethanol at 20℃; for 72h; | 77% |
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol; water for 0.166667h; | 77% |
1,2,3-Benzotriazole
enrofloxacin
3-(1H-benzo[d][1,2,3]triazole-1-carbonyl)-1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoroquinolin-4(1H)-one
Conditions | Yield |
---|---|
With thionyl chloride In dichloromethane at 20℃; | 76% |
enrofloxacin
isopropylamine
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; | 76% |
Conditions | Yield |
---|---|
Stage #1: vanadium(V) oxychloride; enrofloxacin With sodium hydroxide In ethanol at 20℃; for 1h; Stage #2: triethylamine In ethanol at 20℃; for 72h; | 76% |
enrofloxacin
Conditions | Yield |
---|---|
With potassium hydroxide In methanol a MeOH soln. of 2 equiv. of F-compd. deprotonated with 2 equiv. of KOH was added to the Mo-compd. soln. in MeOH, reflux for 2.5 h; soln. was filtered and left to slowly evaporate for a few days, crystalswere filtered off, washed with MeOH and dried, elem. anal.; | 75% |
enrofloxacin
Mn(1-cyclopropyl-7-(4-ethyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylato)2(H2O)2
Conditions | Yield |
---|---|
With potassium hydroxide In methanol a soln. of ligand deprotonated with KOH, added to a soln. of Mn salt, refluxed for 2 h; filtered, crystd. for days, filtered, washed (MeOH), dried; elem. anal.; | 75% |
Conditions | Yield |
---|---|
With sodium hydroxide In acetonitrile | 75% |
Conditions | Yield |
---|---|
With sodium hydroxide In methanol at 20℃; for 2h; | 74.1% |
vanadium(V) oxychloride
enrofloxacin
N,N-dimethyl-formamide
Conditions | Yield |
---|---|
Stage #1: vanadium(V) oxychloride; enrofloxacin With sodium hydroxide In ethanol at 20℃; for 1h; Stage #2: N,N-dimethyl-formamide In ethanol at 20℃; for 72h; | 74% |
Conditions | Yield |
---|---|
Stage #1: vanadium(V) oxychloride; enrofloxacin With sodium hydroxide In ethanol at 20℃; for 1h; Stage #2: pyridine In ethanol at 20℃; for 72h; | 73% |
boron trifluoride diethyl etherate
enrofloxacin
Conditions | Yield |
---|---|
In dichloromethane; N,N-dimethyl-formamide for 24h; Reflux; | 71% |
enrofloxacin
Co(1-cyclopropyl-7-(4-ethyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylato)2(H2O)2
Conditions | Yield |
---|---|
With potassium hydroxide In methanol a soln. of ligand deprotonated with KOH, added to a soln. of Co salt, refluxed; filtered, crystd., filtered, washed (MeOH), dried; elem. anal.; | 70% |
pyridine
methanol
water
enrofloxacin
zinc(II) chloride
Conditions | Yield |
---|---|
With KOH In methanol KOH added to MeOH soln. of enrofloxacin; added to MeOH soln. of ZnCl2; pyridine added; crystd. by slow evapn. after 10 d; elem. anal.; | 70% |
[2,2]bipyridinyl
enrofloxacin
zinc(II) chloride
[Zn(erx)(bipy)Cl]
Conditions | Yield |
---|---|
Stage #1: enrofloxacin With potassium hydroxide In methanol at 20℃; for 0.333333h; Stage #2: [2,2]bipyridinyl; zinc(II) chloride In methanol | 70% |
Conditions | Yield |
---|---|
Stage #1: methanol; enrofloxacin With potassium hydroxide for 0.5h; Stage #2: methanol; 1,10-Phenanthroline; manganese(II) chloride tetrahydrate for 1h; | 70% |
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