dodecyl benzenesulphonate
1-dodecylbromide
Conditions | Yield |
---|---|
With lithium bromide In tetrahydrofuran for 0.5h; Inert atmosphere; Reflux; | 98% |
Conditions | Yield |
---|---|
With allyl bromide; 1,1'-carbonyldiimidazole In acetonitrile for 2h; Heating; | 97% |
With hydrogen bromide; 1-dodecylpyridinium bromide for 1.5h; Irradiation; | 91% |
Stage #1: 1-dodecyl alcohol With copper(l) chloride; diisopropyl-carbodiimide at 20℃; for 0.5h; Stage #2: With N-Bromosuccinimide In 1,2-dichloro-ethane at 80℃; for 4.5h; | 90% |
Conditions | Yield |
---|---|
With 2,2,4-trimethylpentane; tetradecafluorohexane; bromine at 20℃; for 2h; Irradiation; | 96% |
With pyridine; bromine; dichloroaluminum hydride; triethyl borane 1) ether, RT, 2) -78 deg C, 1 h; Yield given. Multistep reaction; |
dodecyl mesylate
1-dodecylbromide
Conditions | Yield |
---|---|
With lithium bromide In tetrahydrofuran for 0.5h; Inert atmosphere; Reflux; | 95% |
With lithium bromide In acetone for 12h; Heating; | |
With sodium bromide |
Conditions | Yield |
---|---|
With hexane; bromine at 20℃; for 2h; Irradiation; | A 10% B 90% |
With hexane; tetradecafluorohexane; bromine at 20℃; for 2h; Irradiation; | A 68% B 32% |
Conditions | Yield |
---|---|
With N-Bromosuccinimide; triphenylphosphine In dichloromethane at 20℃; for 13h; | 80% |
1-dodecyl alcohol
benzoyl chloride
A
dodecyl benzoate
B
1-dodecylbromide
Conditions | Yield |
---|---|
With diphenylcyclopropenone; sodium bromide In acetone at 40℃; for 13h; | A n/a B 78% |
Conditions | Yield |
---|---|
With bis(cyclopentadienyl)titanium dichloride; triethylaluminum; 1,2-dibromomethane In hexane at 20℃; for 24h; Solvent; | A 77% B 22% |
Conditions | Yield |
---|---|
With N-Bromosuccinimide In tetrahydrofuran for 16h; Ambient temperature; Irradiation; | A n/a B 65% |
Conditions | Yield |
---|---|
Stage #1: dodecane With IrH5(P-(i-Pr)3)2; tert-butylethylene at 150℃; for 6h; Inert atmosphere; Stage #2: With Schwartz's reagent In tetrahydrofuran at 40℃; for 12h; Inert atmosphere; Stage #3: With N-Bromosuccinimide In tetrahydrofuran at 25℃; for 1h; Inert atmosphere; regioselective reaction; | 57% |
Conditions | Yield |
---|---|
With dibromobis(cyclopentadienyl)titanium(IV); triethylaluminum In hexane at 20℃; for 24h; Solvent; | A 31% B 37% C 21% |
C18H30Br2Se
1-dodecylbromide
Conditions | Yield |
---|---|
With bromide Ambient temperature; Yield given; |
Conditions | Yield |
---|---|
With sodium bromide In N,N-dimethyl-formamide at 70℃; Yield given; |
2-(8-bromooctyloxy)tetrahydropyran
1-dodecylbromide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 1.) Li2CuCl4, 2.) PTSA / 1.) THF, room temperature, 12 h, 2.) CH3OH, room temperature, 6 h 2: pyridine / CH2Cl2 / 12 h / Ambient temperature 3: LiBr*H2O / acetone / 12 h / Heating View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 85 percent / 47percent HBr / benzene / 48 h / Heating 2: 91 percent / PPTS / CH2Cl2 / 2 h / Ambient temperature 3: 1.) Li2CuCl4, 2.) PTSA / 1.) THF, room temperature, 12 h, 2.) CH3OH, room temperature, 6 h 4: pyridine / CH2Cl2 / 12 h / Ambient temperature 5: LiBr*H2O / acetone / 12 h / Heating View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine / CH2Cl2 / 12 h / Ambient temperature 2: LiBr*H2O / acetone / 12 h / Heating View Scheme |
8-bromooctanol
1-dodecylbromide
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 91 percent / PPTS / CH2Cl2 / 2 h / Ambient temperature 2: 1.) Li2CuCl4, 2.) PTSA / 1.) THF, room temperature, 12 h, 2.) CH3OH, room temperature, 6 h 3: pyridine / CH2Cl2 / 12 h / Ambient temperature 4: LiBr*H2O / acetone / 12 h / Heating View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 2: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 3: 65 percent / NBS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 2: 65 percent / NBS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: bromine / CCl4 / Ambient temperature 2: sodium bromide / dimethylformamide / 70 °C View Scheme |
ethylene glycol mono-n-dodecyl ether
A
2-bromoethyl n-dodecyl ether
B
1-dodecylbromide
Conditions | Yield |
---|---|
With pyridine; phosphorus tribromide at -10 - 25℃; for 2h; | A 85 %Spectr. B 15 %Spectr. |
Conditions | Yield |
---|---|
Stage #1: 4-hydroxy-benzaldehyde With potassium carbonate In N,N-dimethyl-formamide at 20 - 60℃; for 1h; Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide at 80℃; Inert atmosphere; | 100% |
With potassium carbonate In N,N-dimethyl-formamide | 99% |
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 4h; Inert atmosphere; | 98% |
1-dodecylbromide
triphenylphosphine
dodecyltriphenylphosphonium bromide
Conditions | Yield |
---|---|
In toluene Reflux; | 100% |
In 5,5-dimethyl-1,3-cyclohexadiene at 120℃; for 48h; | 96.1% |
In tetrahydrofuran for 12h; sealed tube, bath temperature 250 deg C; | 88% |
Conditions | Yield |
---|---|
With indium(III) bromide; zinc In N,N-dimethyl-formamide at 100℃; for 1h; | 100% |
With ruthenium trichloride; zinc In N,N-dimethyl-formamide at 100℃; for 1h; | 98% |
With RhCl(PPh3)3; hydrogen; triethylamine In tetrahydrofuran at 50℃; under 760 Torr; for 24h; | 97% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 48h; Williamson ether synthesis; Reflux; | 100% |
With potassium carbonate In acetone for 48h; Heating; | 95% |
With potassium carbonate; potassium iodide In acetone for 48h; Reflux; | 95% |
methyl galloate
1-dodecylbromide
methyl [3,4,5-tris(n-dodecan-1-yloxy)]benzoate
Conditions | Yield |
---|---|
Stage #1: methyl galloate With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 2h; Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide at 80℃; | 100% |
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 4h; Inert atmosphere; | 98% |
With 18-crown-6 ether; potassium carbonate In acetone Reflux; | 96% |
Conditions | Yield |
---|---|
Stage #1: thiophenol With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide at 0 - 20℃; for 1h; | 100% |
With potassium hydroxide | |
With potassium hydroxide In ethanol for 5h; Ambient temperature; | |
With potassium carbonate In acetone for 15h; Heating; |
1-dodecylbromide
methyl 4-hydroxylbenzoate
methyl 4-(dodecyloxy)benzoate
Conditions | Yield |
---|---|
With potassium carbonate; sodium iodide In acetonitrile for 24h; Heating; | 100% |
With potassium carbonate In N,N-dimethyl-formamide for 20h; Inert atmosphere; Reflux; | 98% |
Stage #1: methyl 4-hydroxylbenzoate With potassium carbonate In acetonitrile at 70℃; Inert atmosphere; Stage #2: 1-dodecylbromide In acetonitrile for 12h; Reflux; Inert atmosphere; | 96% |
Conditions | Yield |
---|---|
With sodium tetrahydroborate; 2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin; PE-Sn(Bu)2Cl In toluene at 110℃; for 16h; Rate constant; Product distribution; other polyethylene- and polystyrene-bound tin halides, other alkyl and aryl bromides and iodides, var. amounts of catalyst; | 100% |
With triethyl borane; tri-n-butyl-tin hydride In hexane; toluene at -78℃; for 0.5h; | 100% |
With ytterbium(II) iodide In tetrahydrofuran at 60℃; for 8h; Irradiation; | 99% |
1-dodecylbromide
dodecyl azide
Conditions | Yield |
---|---|
With sodium azide In methanol Reflux; | 100% |
With sodium azide In N,N-dimethyl-formamide at 80℃; for 24h; Inert atmosphere; | 100% |
With sodium azide; Aliquat 336 In formamide at 100℃; Rate constant; Product distribution; further solvent; | 99% |
terephthalic acid
1-dodecylbromide
bis-dodecyl benzene-1,4-dicarboxylate
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In benzene for 18h; Esterification; Heating; | 100% |
1-dodecylbromide
5,11,17,23-tetra-tert-butyl-26,28-bis((dimethyl(thiocarbamoyl))oxy)calix<4>arene-25,27-diol
C74H114N2O4S2
Conditions | Yield |
---|---|
With sodium hydride In tetrahydrofuran for 8h; Etherification; Heating; | 100% |
Conditions | Yield |
---|---|
With potassium carbonate Williamson's etherification; | 100% |
With potassium hydroxide In dimethyl sulfoxide at 50℃; Inert atmosphere; | 96% |
With potassium carbonate In N,N-dimethyl-formamide at 70℃; | 95.3% |
1-dodecylbromide
β,β-dimethyl-N,N-dimethyl-4-piperidineethanamine
Conditions | Yield |
---|---|
With potassium carbonate; sodium iodide In acetonitrile for 8h; Heating; | 100% |
Conditions | Yield |
---|---|
With RhCl(PPh3)3; hydrogen; triethylamine In tetrahydrofuran at 50℃; under 760 Torr; for 24h; | 100% |
With hydrogen; triethylamine In tetrahydrofuran at 65℃; under 760.051 Torr; for 24h; Temperature; Solvent; Time; Inert atmosphere; Green chemistry; | 93% |
Conditions | Yield |
---|---|
In neat (no solvent) at 60℃; for 24h; Inert atmosphere; | 100% |
at 130℃; for 0.133333h; Microwave irradiation; Neat (no solvent); | 98% |
In 1,4-dioxane at 130℃; for 24h; Inert atmosphere; | 94% |
lithium acetylide-ethylenediamine complex
1-dodecylbromide
1-tetradecyne
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 23℃; for 12h; | 100% |
1-dodecylbromide
n-octyl 4,6-O-benzylidene-β-D-glucopyranoside
Conditions | Yield |
---|---|
Stage #1: n-octyl 4,6-O-benzylidene-β-D-glucopyranoside With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.25h; Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide at 20℃; for 2h; Further stages.; | 100% |
3-amino-4-chloro-benzoic acid
1-dodecylbromide
n-dodecyl 3-amino-4-chlorobenzoate
Conditions | Yield |
---|---|
With potassium hydroxide; tetrabutylammomium bromide In water; xylene at 140℃; for 5h; Product distribution / selectivity; | 100% |
With potassium carbonate In methanol; water; ethyl acetate; N,N-dimethyl-formamide | 95% |
1,2-dimethyl-1H-imidazole
1-dodecylbromide
1-dodecyl-2,3-dimethylimidazol-1-ium bromide
Conditions | Yield |
---|---|
In neat (no solvent) at 60℃; for 24h; Inert atmosphere; | 100% |
at 20℃; Inert atmosphere; | 90% |
at 140℃; for 0.133333h; Microwave irradiation; Neat (no solvent); |
Conditions | Yield |
---|---|
Stage #1: perylene-3,4,9,10-tetracarboxylic acid 3,4:9,10-dianhydride With potassium hydroxide In water Stage #2: 1-dodecylbromide With potassium iodide | 100% |
With Aliquat 336; potassium iodide; potassium hydroxide Inert atmosphere; | 96% |
With 1-dodecyl alcohol; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 60℃; for 12h; | 86% |
1-dodecylbromide
cetyl azide
Conditions | Yield |
---|---|
With sodium azide In N,N-dimethyl-formamide at 20℃; for 12h; | 100% |
1-methyl-1,3-dihydro-imidazole-2-thione
1-dodecylbromide
2-Dodecylsulfanyl-1-methyl-1H-imidazole; hydrobromide
Conditions | Yield |
---|---|
In acetonitrile for 24h; Reflux; | 100% |
Conditions | Yield |
---|---|
Stage #1: 1-methyl-1H-imidazole; 1-dodecylbromide In neat (no solvent) Reflux; Inert atmosphere; Stage #2: iron(III) chloride hexahydrate Inert atmosphere; | 100% |
1-dodecylbromide
Conditions | Yield |
---|---|
With 18-crown-6 ether In N,N-dimethyl-formamide at 20℃; for 24.5h; | 100% |
With 18-crown-6 ether In acetonitrile at 20℃; for 24h; Reagent/catalyst; Temperature; | 100% |
1-dodecylbromide
1-(2-methoxyphenyl)-imidazole
Conditions | Yield |
---|---|
In tetrahydrofuran at 70℃; | 100% |
1-dodecylbromide
1-o-tolyl-1H-imidazole
Conditions | Yield |
---|---|
In tetrahydrofuran at 70℃; | 100% |
Conditions | Yield |
---|---|
With sodium hydroxide In water; toluene | 99.6% |
With sodium hydroxide In toluene | 95% |
With sodium hydroxide; tetrabutylammomium bromide; potassium carbonate In cyclohexane | 92.8% |
Conditions | Yield |
---|---|
With sodium iodide In acetone at 20℃; for 55.5h; Inert atmosphere; | 99% |
With 1,3-di-n-octyl-2-phenylimidazolium bromide; potassium iodide In toluene at 40℃; for 20h; | 68% |
With sodium iodide; (β-CD) - epichlorohydrin copolymer In water at 90℃; Rate constant; catalytic activity, EP/β-CD ratio, concentration of catalyst, various nucleophiles, reactivity order of nucleophiles; |
Conditions | Yield |
---|---|
In ethyl acetate at 20℃; for 24h; | 99% |
In acetone at 20 - 50℃; for 1.5h; | 66% |
In diethyl ether for 48h; Ambient temperature; | 37% |
Conditions | Yield |
---|---|
In acetonitrile at 80℃; for 48h; | 99% |
In methanol for 36h; Heating; | |
In acetonitrile |
The IUPAC name of this chemical is 1-Bromododecane. With the CAS registry number 143-15-7 and EINECS registry number 205-587-9, it is also named as dodecane, 1-bromo-. In addition, the molecular formula is C12H25Br. It is a kind of colorless to light yellow liquid and incompatible with strong oxidizing agents and strong bases. And it is mainly used in organic synthesis.
Physical properties about this chemical are: (1)ACD/LogP: 6.99; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.99; (4)ACD/LogD (pH 7.4): 6.99; (5)ACD/BCF (pH 5.5): 121511.97; (6)ACD/BCF (pH 7.4): 121511.97; (7)ACD/KOC (pH 5.5): 151756.92; (8)ACD/KOC (pH 7.4): 151756.92; (9)Index of Refraction: 1.457; (10)Molar Refractivity: 65.37 cm3; (11)Molar Volume: 239.7 cm3; (12)Polarizability: 25.91 ×10-24cm3; (13)Surface Tension: 30.1 dyne/cm; (14)Density: 1.039 g/cm3; (15)Flash Point: 113 °C; (16)Enthalpy of Vaporization: 49.4 kJ/mol; (17)Boiling Point: 276.2 °C at 760 mmHg; (18)Vapour Pressure: 0.00817 mmHg at 25°C.
Preparation of 1-Bromododecane: it can be prepared by dodecan-1-ol. Add the dodecan-1-ol into the reactor at first. Then add sulfuric acid slowly in the reactor with stirring for 1 hour. Next, add hydrogen bromide into the mixture. The reaction should react for 8 hours at temperature of 90-95 °C with stirring. After the reaction, you can go through cooling, separation, neutralization, washing by ethanol and vacuum distillation to get this chemical. The yield is above 90%.
Uses of 1-Bromododecane: it can react with methylamine to get dodecyl-methyl-amine. This reaction will need solvent ethanol. The reaction time is 3 days with ambient temperature. The yield is about 94%.
When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. During using it, wear suitable protective clothing and avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES: BrCCCCCCCCCCCC
(2)Std. InChI: InChI=1S/C12H25Br/c1-2-3-4-5-6-7-8-9-10-11-12-13/h2-12H2,1H3
(3)Std. InChIKey: PBLNBZIONSLZBU-UHFFFAOYSA-N
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