2-Methyl-3-buten-2-ol supplier

Name
2-Methyl-3-buten-2-ol
EINECS 204-068-4
CAS No. 115-18-4
Article Data182
CAS DataBase
Density 0.83 g/cm³
Solubility
Melting Point -43 °C
Formula C₅H₁₀O
Boiling Point 98.499 °C at 760 mmHg
Molecular Weight 86.1338
Flash Point 12.842 °C
Transport Information UN 1987 3/PG 2
Appearance clear colourless to very slightly yellow liquid
Safety 16-26-36
Risk Codes 11-22-36
Molecular Structure
Hazard Symbols F, Xn, F++
Synonyms 1,1-Dimethyl-2-propen-1-ol;1,1-Dimethyl-2-propenyl alcohol;1,1-Dimethylallyl alcohol;2-Methyl-2-hydroxy-3-butene;2-Methyl-3-buten-2-yl alcohol;3-Hydroxy-3-methyl-1-butene;3-Hydroxy-3-methylbutene;3-Methyl-3-hydroxybutene;Dimethylvinylcarbinol;Dimethylvinylmethanol;Vinyldimethylcarbinol;a,a-Dimethylallyl alcohol;
PSA 20.23000
LogP 0.94330

Synthetic route

: 115-19-5
2-methyl-but-3-yn-2-ol

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With quinoline; hydrogen; Lindlar's catalyst In Petroleum ether at 20℃; for 10h;	99%
With pyridine; hydrogen In methanol at 59.84℃; Kinetics; Temperature; Reagent/catalyst; Concentration; Time; Capillary microreactor; chemoselective reaction;	99.9%
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760.051 Torr;	98%

: 78-79-5
isoprene

A: 115-18-4
2-methyl-3-buten-2-ol

B: isopentenol

Conditions

Conditions	Yield
Stage #1: isoprene With hydrogenchloride at 1℃; for 3h; Stage #2: With sodium hydroxide In cyclohexane at 70℃; for 1.58333h; Temperature;	A 99.75% B 98%

: 115-19-5
2-methyl-but-3-yn-2-ol

A: 75-85-4
tert-Amyl alcohol

B: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760 Torr; Kinetics;	A n/a B 98%
With hydrogen; palladium dichloride In N,N-dimethyl-formamide under 18751.5 Torr; for 0.3h; Product distribution; Ambient temperature; various time;	A 2% B 91%
With hydrogen; nickel dihydroxide; Ni(C17H35COO)2 In toluene at 40℃; Product distribution; Kinetics; other catalyst. Object of study: selectivity;	A 41.6% B 85.5%

: 2190-48-9
3-chloro-3-methyl-1-butene

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
Stage #1: 3-chloro-3-methyl-1-butene With sodium formate; copper(II) sulfate; erythorbic acid sodium salt In water for 5h; Reflux; Stage #2: With sodium hydroxide In water at 90℃; for 2h; Reagent/catalyst;	97%
With sodium hydrogencarbonate at 45℃;
Multi-step reaction with 2 steps 1: 20 °C / bei 3 Monate langem Stehenlassen 2: NaHCO3 / 50 °C View Scheme
Multi-step reaction with 2 steps 1: 0 °C 2: NaHCO3 / 50 °C View Scheme

: 917-54-4
methyllithium

: 78-94-4
methyl vinyl ketone

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
In diethyl ether at -78℃; for 0.166667h;	90%
In diethyl ether at -78℃;	90%
In diethyl ether at -78℃; for 0.166667h; Inert atmosphere; Schlenk technique;	88%

: 556-82-1
3-methyl-2-buten-1-ol

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With silica-supported monomeric vanadium-oxo species In acetonitrile at 40℃; for 4h; Inert atmosphere;	76%
With acide perchlorique In water-d2 at 34℃; Product distribution;
With sulfuric acid

: 513-35-9
2-methyl-but-2-ene

A: 19482-44-1
2-(oxiran-2-yl)propan-2-ol

B: 36688-49-0
1-(2-methyl-oxiranyl)-ethanol

C: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With titanium(IV) isopropylate; oxygen; 5,15,10,20-tetraphenylporphyrin In dichloromethane at 0℃; Irradiation;	A 47% B 38% C 3%

...Expand

: 625-27-4
2-methyl-2-pentene

A: 1193-04-0
α,α,3-Trimethyloxiranemethanol

B: 115-18-4
2-methyl-3-buten-2-ol

C: 96481-55-9
2-methylpent-1-en-3-ol

D: 28255-29-0, 113531-35-4
1-(2-Methyl-oxiranyl)-propan-1-ol

Conditions

Conditions	Yield
With titanium(IV) isopropylate; oxygen; 5,15,10,20-tetraphenylporphyrin In dichloromethane at 0℃; Irradiation;	A 42% B 3% C 3% D 28%

...Expand

: 78-79-5
isoprene

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
	30%
With hydrogenchloride; acetic acid Behandeln des Reaktionsprodukts mit Calciumcarbonat und Wasser;
Multi-step reaction with 2 steps 1: hydrogen bromide / Endprodukt ist 4-Brom-2-methyl-buten-(2) 2: natrium carbonate View Scheme
10% phosphoric acid on silica at 25℃; for 12h; Product distribution / selectivity; Gas phase; Sealed vial;

: 1670-26-4
sphingosylphosphorylcholine

: 78-79-5
isoprene

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
	29%

: 50-00-0
formaldehyd

: 115-11-7
isobutene

A: 766-15-4
4,4-dimethyl-1,3-dioxane

B: 16302-35-5
4-methyl-3,6-dihydro-2H-pyran

C: 763-32-6
2-methyl-1-buten-4-ol

D: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With sulfuric acid In nitromethane at 30℃; for 0.333333h; Mechanism;	A 8.16% B n/a C 1.79% D 2.5%

...Expand

: 2568-33-4
3-methyl-butane-1,3-diol

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With sulfuric acid

: 2190-48-9
3-chloro-3-methyl-1-butene

: 141-53-7
sodium formate

A: 115-18-4
2-methyl-3-buten-2-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With formic acid Erwaermen des Reaktionsprodukts mit wss.Kalilauge;

...Expand

: 865-58-7
3-bromo-3-methyl-but-1-ene

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With water
With sodium carbonate

: 60-29-7
diethyl ether

: 7486-35-3
tri-n-butyl(vinyl)tin

: 591-51-5
phenyllithium

: 67-64-1
acetone

A: 115-18-4
2-methyl-3-buten-2-ol

B: 960-16-7
tributylphenylstannane

Conditions

Conditions	Yield
und anschliessenden Hydrolysieren;

...Expand

: 60-29-7
diethyl ether

: 917-57-7
vinyllithium

: 67-64-1
acetone

: 115-18-4
2-methyl-3-buten-2-ol

...Expand

: 3536-96-7
vinylmagnesium chloride

: 67-64-1
acetone

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With tetrahydrofuran

: 917-57-7
vinyllithium

: 67-64-1
acetone

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With diethyl ether

: 1826-67-1
vinyl magnesium bromide

: 67-64-1
acetone

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With diethyl ether
Stage #1: vinyl magnesium bromide; acetone In tetrahydrofuran at -78℃; for 3h; Stage #2: With water In tetrahydrofuran Further stages.;
In tetrahydrofuran at 0 - 20℃; for 12h;
In tetrahydrofuran at 0 - 20℃; for 4h; Inert atmosphere;

: 115-19-5
2-methyl-but-3-yn-2-ol

A: 5929-72-6
2,7-dimethyl-octa-3,5-diyne-2,7-diol

B: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
elektrolytische Reduktion an Nickelkathoden.Electrolysis;
With nickel bei der elektrolytischen Reduktion niederer Stromdichte;

: 75-16-1
methylmagnesium bromide

: 140-88-5
ethyl acrylate

: 115-18-4
2-methyl-3-buten-2-ol

: 503-60-6
3,3-dimethyl-allyl chloride

A: 115-18-4
2-methyl-3-buten-2-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sodium hydrogencarbonate at 50℃;

: 503-60-6
3,3-dimethyl-allyl chloride

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With sodium carbonate
Multi-step reaction with 3 steps 1: NaHCO3 / >50 2: hydrogen chloride / 0 °C 3: NaHCO3 / 50 °C View Scheme
With alkali Hydrolysis;

: 766-15-4
4,4-dimethyl-1,3-dioxane

A: 16302-35-5
4-methyl-3,6-dihydro-2H-pyran

B: 763-32-6
2-methyl-1-buten-4-ol

C: 2568-33-4
3-methyl-butane-1,3-diol

D: 7525-64-6
4-hydroxy-4-methyltetrahydropyran

E: 115-18-4
2-methyl-3-buten-2-ol

F: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With sulfuric acid at 120℃; for 3h; Product distribution; various catalyst, various temperature, various time, extent of conversion, solvent cyclohexane;

...Expand

: 2568-33-4
3-methyl-butane-1,3-diol

A: 763-32-6
2-methyl-1-buten-4-ol

B: 115-18-4
2-methyl-3-buten-2-ol

C: 556-82-1
3-methyl-2-buten-1-ol

D: 78-79-5
isoprene

Conditions

Conditions	Yield
With potassium hydrogensulfate at 140℃; for 0.75h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;	A n/a B 8 % Chromat. C n/a D 30 % Chromat.
With potassium hydrogensulfate at 140℃; for 0.75h; Product distribution; investigation of regioselectivity of dehydration with var. reagents in terpene derivatives;	A n/a B 8 % Chromat. C n/a D 30 % Chromat.

...Expand

: 64-18-6
formic acid

: 556-82-1
3-methyl-2-buten-1-ol

A: 115-18-4
2-methyl-3-buten-2-ol

B: 68480-28-4
formiate de methyl-3 butene-2 ol-1

C: 77949-40-7
formiate de methyl-2 butene-3 ol-2

Conditions

Conditions	Yield
In chloroform-d1; dichloromethane at 34℃; for 1h; Product distribution;

...Expand

: 870-63-3
prenyl bromide

A: 115-18-4
2-methyl-3-buten-2-ol

B: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With indium; oxygen 1.) DMF, 1 h, RT, 2.) room temperature, 3 h; Yield given. Multistep reaction. Yields of byproduct given;

: 26902-24-9
3-(benzyloxy)-3-methyl-1-butene

: 115-18-4
2-methyl-3-buten-2-ol

Conditions

Conditions	Yield
With sodium In ammonia Yield given;

: 97567-76-5
3-Methyl-2-butenyl phenyl telluride

A: 115-18-4
2-methyl-3-buten-2-ol

B: 107-86-8
3,3-dimethyl acrylaldehyde

C: 556-82-1
3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With oxygen at 15 - 20℃; for 1h; var. oxidants and time.; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With dihydrogen peroxide at 15 - 20℃; for 2h; var. oxidants and time.; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 115-19-5
2-methyl-but-3-yn-2-ol

A: 115-18-4
2-methyl-3-buten-2-ol

B: 123-51-3
i-Amyl alcohol

Conditions

Conditions	Yield
With hydrogen; copper-palladium In water at 20℃; Product distribution; Kinetics; various catalysts, solvents, temperature;
With hydrogen; copper-palladium In water at 20℃; Yield given. Yields of byproduct given;
With hydrogen; copper-palladium In water at 20℃; Yield given. Yields of byproduct given;

: 115-18-4
2-methyl-3-buten-2-ol

: 108-24-7
acetic anhydride

: 24509-88-4
2-methyl-3-buten-2-yl acetate

Conditions

Conditions	Yield
indium(III) chloride In acetonitrile at 20℃; for 0.5h;	100%
With dmap; triethylamine In dichloromethane at 20℃;	91%
With dmap; triethylamine In dichloromethane at 20℃; Cooling with ice; Inert atmosphere;	91%

: 75-75-2
methanesulfonic acid

: 115-18-4
2-methyl-3-buten-2-ol

: 5952-75-0
Δ3-Isopentenyl methyl sulfide

: 100669-10-1
isopentenyl methyl prenyl sulfonium methane sulfonate

Conditions

Conditions	Yield
In dichloromethane for 72h; Ambient temperature;	100%

...Expand

: 5707-04-0
Phenylselenyl chloride

: 115-18-4
2-methyl-3-buten-2-ol

: 99018-46-9
3-methyl-2-(phenylselenyl)-1,3-butanediol

Conditions

Conditions	Yield
In water; acetonitrile for 2h; Ambient temperature;	100%
With water In acetonitrile at 20℃; for 24h;	86%

: 115-18-4
2-methyl-3-buten-2-ol

: 861216-48-0
tert-butyl 2-methylbut-3-en-2-yl carbonate

Conditions

Conditions	Yield
Stage #1: 2-methyl-3-buten-2-ol With n-butyllithium In tetrahydrofuran; hexane at -78℃; Inert atmosphere; Stage #2: With 2,2-dimethylpropanoic anhydride In tetrahydrofuran; hexane at -78 - 20℃;	100%

: 115-18-4
2-methyl-3-buten-2-ol

: 543-27-1
isobutyl chloroformate

: 1,1-dimethylpropenyl isobutyl carbonate

Conditions

Conditions	Yield
Stage #1: 2-methyl-3-buten-2-ol With n-butyllithium In tetrahydrofuran; hexane at 0℃; Inert atmosphere; Stage #2: isobutyl chloroformate In tetrahydrofuran; hexane at 0 - 20℃;	100%

: 694-32-6
1-methyl-2-imidazolidone

: 115-18-4
2-methyl-3-buten-2-ol

: 1215309-24-2
1-methyl-3-(3-methylbut-2-enyl)imidazolidin-2-one

Conditions

Conditions	Yield
With silver hexafluoroantimonate; 2-(di-tert-butylphosphino)-1,1'-biphenylgold(I) chloride In 1,4-dioxane at 60℃; for 24h; Inert atmosphere;	100%

: 110-87-2
3,4-dihydro-2H-pyran

: 115-18-4
2-methyl-3-buten-2-ol

: 2-((2-methylbut-3-en-2-yl)oxy)tetrahydro-2H-pyran

Conditions

Conditions	Yield
With 1,5-dichloro-9,10-anthraquinone In dichloromethane for 0.5h; UV-irradiation;	99%
With trifluoroacetic acid In dichloromethane at 20℃;	70%
With trifluoroacetic acid In dichloromethane at 20℃;	70%
With Ersorb-4 zeolite at 20℃; for 1h;	74 % Spectr.

: 115-18-4
2-methyl-3-buten-2-ol

: 86547-31-1
(3S)-3,4-Epoxy-2-methyl-2-butanol

Conditions

Conditions	Yield
With (R,R)-N-[2-(diphenylacetylhydroxyamino)cyclohexyl]-N-hydroxy-2,2-diphenylacetamide; Cumene hydroperoxide; hafnium(IV) tert-butoxide; magnesium oxide In toluene at 0 - 5℃; for 48h; Inert atmosphere; Glovebox; enantioselective reaction;	99%

: 115-18-4
2-methyl-3-buten-2-ol

: 1714-29-0
1-bromopyrene

: 1-(3-hydroxy-3-methyl-1-butynyl)pyrene

Conditions

Conditions	Yield
With copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; triethylamine; triphenylphosphine In toluene at 80℃; Inert atmosphere;	99%

: 115-18-4
2-methyl-3-buten-2-ol

: (6-piperidin-1-yl-9H-purin-9-yl)acetaldehyde oxime

: 2-{3-[(6-piperidin-1-yl-9H-purin-9-yl)methyl]-4,5-dihydroisoxazol-5-yl}propan-2-ol

Conditions

Conditions	Yield
With bis-[(trifluoroacetoxy)iodo]benzene at 20℃; for 0.166667h;	99%

: 288-32-4
1H-imidazole

: 115-18-4
2-methyl-3-buten-2-ol

: 403485-90-5
N-(dimethylallyl)imidazole

Conditions

Conditions	Yield
With 2,3,4,5,6-pentafluorophenol; briphos; bis(dibenzylideneacetone)-palladium(0) In dichloromethane at 30℃; for 6h; Inert atmosphere; regioselective reaction;	99%

: 115-18-4
2-methyl-3-buten-2-ol

: 2-bromo-N-[(R)-2-((tert-butyldimethylsilyl)oxy)-1-phenylethyl]-2-methylheptanamide

: 2-(2-ethenyl-2-propoxy)-N-[(R)-2-((tert-butyldimethylsilyl)oxy)-1-phenylethyl]-2-methylheptanamide

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile at 20℃; for 72h; Inert atmosphere; stereoselective reaction;	99%

: 607-66-9
4-methyl-1,2-dihydroquinolin-2-one

: 115-18-4
2-methyl-3-buten-2-ol

: 82912-82-1
1-(1-Hydroxy-1-methyl-ethyl)-8b-methyl-2,2a,4,8b-tetrahydro-1H-cyclobuta[c]quinolin-3-one

Conditions

Conditions	Yield
In methanol Product distribution; Irradiation; 2+2 adducts with heteroaromatics involving an enone function; in a second step with acids 3,3-dimethylallylated products;	98%
In methanol Irradiation;	98%

: 914086-83-2
tert-butyl-(3,6-dimethyl-2-vinyl-2,3-dihydro-benzofuran-5-yloxy)-dimethyl-silane

: 115-18-4
2-methyl-3-buten-2-ol

: 914086-85-4
(E)-4-[(S)-5-(tert-Butyl-dimethyl-silanyloxy)-3,6-dimethyl-2,3-dihydro-benzofuran-2-yl]-2-methyl-but-3-en-2-ol

Conditions

Conditions	Yield
chiral Ru(IV) complex In dichloromethane for 20h; Heating;	98%

: 74-93-1
methylthiol

: 115-18-4
2-methyl-3-buten-2-ol

: 1-methylthio-3-hydroxy-3-methyl-butane

Conditions

Conditions	Yield
With triethyl borane	98%

: 1279123-63-5
potassium hydrogenfluoride

: 13675-18-8
tetrahydroxydiboron

: 115-18-4
2-methyl-3-buten-2-ol

: potassium trifluoro(3-methylbut-2-en-1-yl)borate

Conditions

Conditions	Yield
[1,3-bis(phenylselenomethyl)phenyl]palladium(II) chloride In methanol; dimethyl sulfoxide react. (B(OH)2)2 with olefine at 50°C for 16 h in mixt. DMSO-MeOH, aq. KHF2 was added;	98%

...Expand

: 115-18-4
2-methyl-3-buten-2-ol

: 20776-50-5
2-amino-4-bromobenzoic acid

: (E)-2-amino-4-(3-hydroxy-3-methylbut-1-enyl)benzoic acid

Conditions

Conditions	Yield
With palladium diacetate; sodium 3-(diphenylphosphanyl)benzenesulfonate; sodium hydroxide In water at 100℃; for 48h; Heck reaction; chemoselective reaction;	98%

: 626-55-1
3-Bromopyridine

: 115-18-4
2-methyl-3-buten-2-ol

: 943897-36-7
(E)-2-methyl-4-(pyridin-3-yl)but-3-en-2-ol

Conditions

Conditions	Yield
With dicyclohexyl(2',4',6'-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane; palladium diacetate; sodium hydrogencarbonate In N,N-dimethyl-formamide at 120℃; for 8h; Sealed tube; Inert atmosphere; Glovebox; Schlenk technique;	98%
With C48H42Cl2O4P4Pd2; sodium acetate In N,N-dimethyl-formamide at 90℃; for 6h; Heck reaction; regioselective reaction;	88%

: 1943-82-4
phenethyl isocyanate

: 115-18-4
2-methyl-3-buten-2-ol

: 1413940-97-2
N-(2-phenylethyl)-N-(1,1-dimethylallyloxy)carbonylamide

Conditions

Conditions	Yield
With triethylamine at 20 - 100℃; for 12h; Inert atmosphere;	98%

: 115-18-4
2-methyl-3-buten-2-ol

: 442155-91-1
4-methyl-N-{2-(phenylethynyl)phenyl}benzenesulfonamide

: C26H25NO2S

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; sodium 3-(diphenylphosphanyl)benzenesulfonate In 1,4-dioxane; water for 1h; Reflux; Inert atmosphere;	98%

: 115-18-4
2-methyl-3-buten-2-ol

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 89171-33-5
N,N,5-trimethylhex-4-enamide

Conditions

Conditions	Yield
In toluene at 180℃; for 5h; Sealed tube;	98%

: 115-18-4
2-methyl-3-buten-2-ol

: 69739-34-0
t-butyldimethylsiyl triflate

: tert-butyldimethyl ((2-methylbut-3-en-2-yl)oxy)silane

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 3h;	98%

: 1445-45-0
Trimethyl orthoacetate

: 115-18-4
2-methyl-3-buten-2-ol

: 63721-05-1
methyl 3,3-dimethyl-4-penteneoate

Conditions

Conditions	Yield
With phosphoric acid at 190℃; under 9750.98 Torr; for 20h; Temperature; Claisen Rearrangement;	97.2%

: 115-18-4
2-methyl-3-buten-2-ol

: Acetic acid (1S,2S,5R,6R)-3-bromo-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-en-2-yl ester

: Acetic acid (1R,2R,5R,6R)-5-(tert-butyl-dimethyl-silanyloxy)-3-((E)-3-hydroxy-3-methyl-but-1-enyl)-7-oxa-bicyclo[4.1.0]hept-3-en-2-yl ester

Conditions

Conditions	Yield
With silver carbonate; palladium diacetate In N,N-dimethyl-formamide at 90℃; Heck reaction;	97%

: 115-18-4
2-methyl-3-buten-2-ol

: 375-50-8
1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane

: 5,5,6,6,7,7,8,8-octafluoro-3,10-diiodo-2,11-dimethyldodecan-2,11-diol

Conditions

Conditions	Yield
With sodium dithionite; sodium hydrogencarbonate In acetonitrile at 20℃; for 4h;	97%

: 115-18-4
2-methyl-3-buten-2-ol

: 24424-99-5
di-tert-butyl dicarbonate

: 861216-48-0
tert-butyl 2-methylbut-3-en-2-yl carbonate

Conditions

Conditions	Yield
Stage #1: 2-methyl-3-buten-2-ol With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 0.333333h; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; hexane at 0 - 23℃; for 4h;	97%
Stage #1: 2-methyl-3-buten-2-ol With n-butyllithium In tetrahydrofuran at 0℃; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran	94%
With n-butyllithium In tetrahydrofuran at -78 - 20℃;	71%
Stage #1: 2-methyl-3-buten-2-ol With methylmagnesium chloride In tetrahydrofuran; diethyl ether at 0℃; for 0.5h; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; diethyl ether at 0 - 20℃; Further stages.;	55%
Stage #1: 2-methyl-3-buten-2-ol With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 0.25h; Inert atmosphere; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; hexane at 20℃; for 3h; Inert atmosphere;

2-Methyl-3-buten-2-ol Chemical Properties

Molecular Structure of 2-Methyl-3-buten-2-ol (115-18-4):

IUPAC Name: 2-Methylbut-3-en-2-ol
Molecular Formula: C₅H₁₀O
Molecular Weight: 86.132300 g/mol
EINECS: 204-068-4
XLogP3-AA: 0.8
H-Bond Donor: 1
H-Bond Acceptor: 1
Canonical SMILES: CC(C)(C=C)O
InChI: InChI=1S/C5H10O/c1-4-5(2,3)6/h4,6H,1H2,2-3H3
InChIKey: HNVRRHSXBLFLIG-UHFFFAOYSA-N
Index of Refraction: 1.423
Molar Refractivity: 26.43 cm³
Molar Volume: 103.7 cm³
Surface Tension: 24.9 dyne/cm
Density: 0.83 g/cm³
Flash Point: 12.8 °C
Melting Point: -43 °C
Enthalpy of Vaporization: 39.39 kJ/mol
Boiling Point: 98.5 °C at 760 mmHg
Vapour Pressure: 22.9 mmHg at 25 °C
Water Solubility: 4.874e+004 mg/L at 25 °C
Storage Temperature: Flammables area

2-Methyl-3-buten-2-ol Uses

2-Methyl-3-buten-2-ol (CAS NO.115-18-4) is used to product Vitamin E , Vitamin K1 , Vitamin A , etc.

2-Methyl-3-buten-2-ol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mammal (species unspecified)	LD50	unreported	435mg/kg (435mg/kg)	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
mouse	LD50	intraperitoneal	800mg/kg (800mg/kg)	Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. Vol. 14, Pg. 449, 1976.
mouse	LD50	subcutaneous	1680mg/kg (1680mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 161, 1955.
rat	LD50	intraperitoneal	1315mg/kg (1315mg/kg)	Planta Medica. Vol. 48, Pg. 120, 1983.

2-Methyl-3-buten-2-ol Safety Profile

When heated to decomposition, it yields Carbon monoxide , Carbon dioxide .
Hazard Codes: F, Harmful Xn, Extremely F++
Risk Statements: 11-22-36
R11:Highly flammable.
R22:Harmful if swallowed.
R36:Irritating to eyes.
Safety Statements: 16-26-36
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
RIDADR: UN 1987 3/PG 2
WGK Germany: 1
RTECS: EM9472000
HazardClass: 3
PackingGroup of 2-Methyl-3-buten-2-ol (CAS NO.115-18-4): II

2-Methyl-3-buten-2-ol Specification

2-Methyl-3-buten-2-ol (CAS NO.115-18-4) is also known as 3-Hydroxy-3-methylbutene ; 1,1-Dimethyl-2-propanol ; 1,1-Dimethyl-2-propenol ; 1,1-Dimethylallyl alchol ; 1,1-Dimethylallyl alcohol ; 2-Methyl-2-hydroxy-3-butene ; 2-Methyl-3-buten-2-ol ; 2-Methyl-3-buten-2-yl alcohol ; 3-Buten-2-ol, 2-methyl- ; 3-Hydroxy-3-methylbutene ; 3-Methyl-1-buten-3-ol ; 3-Methyl-buten-(1)-ol-(3) ; Dimethylvinylcarbinol ; Dimethylvinylmethanol ; Methylbutenol ; Vinyldimethylcarbinol ; alpha,alpha-Dimethylallyl alcohol ; 1-Buten-3-ol, 3-methyl- ; 2-Methylbut-3-en-2-ol ; 3-Butyn-2-ol, 2-methyl- (8CI,9CI) . It is colorless - very slightly yellow clear liquid. It is incompatible with strong oxidizing agents. It slightly soluble in water.

Product Name

2-Methyl-3-buten-2-ol

Synthetic route

2-Methyl-3-buten-2-ol Chemical Properties

2-Methyl-3-buten-2-ol Uses

2-Methyl-3-buten-2-ol Toxicity Data With Reference

2-Methyl-3-buten-2-ol Safety Profile

2-Methyl-3-buten-2-ol Specification

Related Products

Hot Products