3,5-Dimethylphenylboronic acid supplier

Name
3,5-Dimethylphenylboronic acid
EINECS 605-655-1
CAS No. 172975-69-8
Article Data20
CAS DataBase
Density 1.07 g/cm³
Solubility Slightly soluble in water
Melting Point 261-265 °C(lit.)
Formula C₈H₁₁BO₂
Boiling Point 312.7 °C at 760 mmHg
Molecular Weight 149.985
Flash Point 142.9 °C
Transport Information
Appearance off-white to light yellow crystalline powder
Safety 37/39-26-36/37
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xn
Synonyms Boronic acid, (3,5-dimethylphenyl)- (9CI);(3,5-Dimethylphenyl)boronic acid;(3,5-Dimethylphenyl)dihydroxyborane;3,5-Dimethylbenzeneboronicacid;
PSA 40.46000
LogP -0.01680

Synthetic route

: 67-56-1
methanol

: 55124-35-1
diisopropylamine borane

: 556-96-7
5-bromo-1,3-xylene

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Stage #1: diisopropylamine borane With magnesium; phenylmagnesium bromide In tetrahydrofuran at 20℃; for 0.166667h; Stage #2: 5-bromo-1,3-xylene In tetrahydrofuran at 70℃; Stage #3: methanol Further stages;	89%

...Expand

: 121-43-7
Trimethyl borate

: 556-96-7
5-bromo-1,3-xylene

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With Mg; H2SO4 In tetrahydrofuran; diethyl ether aryl bromide in THF was added to Mg turnings, filtered, added dropwise with stirring to trimethyl borate in ether at -70°C, the suspn. was allowed to warm to room temp. overnight, added with stirring to ice, concd. H2SO4, stirred for 30 min (Ar); shaken with ether, dried over Na2SO4, evapd., filtered, dried in vac.; elem. anal.;	85.6%
With Mg; iodomethane In diethyl ether under Ar atm. 1,3-dimethyl-5-bromobenzene in Et2O was added slowly to Mgturning in the presence of MeI, react. mixt. was refluxed for 6 h and a dded at -60°C to soln. B(OMe)3 in Et2O, allowed to warm slowly toroom temp. with stirring; react. mixt. was poured into 20% H2SO4, org. phase was separated, washedwith water and dried over MgSO4, solvent was removed in vacuo;	82%

Yield

With Mg; H2SO4 In tetrahydrofuran; diethyl ether aryl bromide in THF was added to Mg turnings, filtered, added dropwise with stirring to trimethyl borate in ether at -70°C, the suspn. was allowed to warm to room temp. overnight, added with stirring to ice, concd. H2SO4, stirred for 30 min (Ar); shaken with ether, dried over Na2SO4, evapd., filtered, dried in vac.; elem. anal.;

85.6%

With Mg; iodomethane In diethyl ether under Ar atm. 1,3-dimethyl-5-bromobenzene in Et2O was added slowly to Mgturning in the presence of MeI, react. mixt. was refluxed for 6 h and a dded at -60°C to soln. B(OMe)3 in Et2O, allowed to warm slowly toroom temp. with stirring; react. mixt. was poured into 20% H2SO4, org. phase was separated, washedwith water and dried over MgSO4, solvent was removed in vacuo;

82%

: 121-43-7
Trimethyl borate

: 7732-18-5
water

: 34696-73-6
3,5-dimethyphenylmagnesium bromide

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Stage #1: Trimethyl borate; 3,5-dimethyphenylmagnesium bromide In tetrahydrofuran at 20℃; Stage #2: water With hydrogenchloride In tetrahydrofuran; diethyl ether	74%

...Expand

: 121-43-7
Trimethyl borate

: 556-96-7
5-bromo-1,3-xylene

: 7732-18-5
water

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Stage #1: Trimethyl borate; 5-bromo-1,3-xylene With magnesium In tetrahydrofuran at -78 - 20℃; Stage #2: water With hydrogenchloride In tetrahydrofuran; diethyl ether	74%

...Expand

: 556-96-7
5-bromo-1,3-xylene

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With Trimethyl borate
Stage #1: 5-bromo-1,3-xylene With magnesium In tetrahydrofuran Stage #2: With Trimethyl borate Stage #3: With hydrogenchloride Further stages.;
Stage #1: 5-bromo-1,3-xylene With magnesium; methyl iodide In diethyl ether Inert atmosphere; Reflux; Stage #2: With Trimethyl borate In diethyl ether at -60 - 20℃; Inert atmosphere;
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C 1.2: -78 - 20 °C 2.1: water; hydrogenchloride / tetrahydrofuran; hexane / 20 °C / pH 3 - 5 View Scheme

: 325142-93-6
2-(3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Stage #1: 2-(3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane With sodium periodate In tetrahydrofuran; water for 0.25h; Stage #2: With hydrogenchloride In tetrahydrofuran; water for 4h;
Stage #1: 2-(3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane With sodium periodate In tetrahydrofuran; water for 0.5h; Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 17h;

: 108-38-3
m-xylene

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: 4,4'-di-tert-butyl-2,2'-bipyridine / [Ir(COD)(OMe)]2 / tetrahydrofuran / 16 h / 80 °C 2.1: sodium periodate / tetrahydrofuran; H2O / 0.25 h 2.2: HCl / H2O; tetrahydrofuran / 4 h View Scheme
Multi-step reaction with 2 steps 1.1: 4,4'-di-tert-butyl-2,2'-bipyridine; pinacolborane / [(COD)Ir(OMe)]2 / cyclohexane / 24 h / 80 °C 2.1: sodium periodate / tetrahydrofuran; H2O / 0.5 h 2.2: hydrochloric acid / tetrahydrofuran; H2O / 17 h / 20 °C View Scheme

: 5419-55-6
Triisopropyl borate

: 556-96-7
5-bromo-1,3-xylene

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With N2 In tetrahydrofuran	2.41 g (29.7%)
With N2 In tetrahydrofuran	2.41 g (29.7%)
With sodium hydroxide; n-butyllithium In tetrahydrofuran; hydrogenchloride; hexane; dichloromethane
Stage #1: 5-bromo-1,3-xylene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.25h; Inert atmosphere; Stage #2: Triisopropyl borate In tetrahydrofuran; hexane at 25℃; for 0.333333h; Inert atmosphere;

: 1016971-57-5
C26H31B3O5

A: 301699-39-8
(4-methoxy-3,5-dimethylphenyl)boronic acid

B: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 1016971-59-7
C25H29B3O4

A: 301699-39-8
(4-methoxy-3,5-dimethylphenyl)boronic acid

B: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 1016971-63-3
C38H55B3O5

A: 172975-69-8
3,5-dimethylphenyl boronic acid

B: 233584-42-4
4-methoxy-3,5-di-tert-butylphenylboronic acid pinacol ester

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 1016971-64-4
C31H41B3O4

A: 172975-69-8
3,5-dimethylphenyl boronic acid

B: 233584-42-4
4-methoxy-3,5-di-tert-butylphenylboronic acid pinacol ester

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 1016971-54-2
C25H29B3O6

A: 172975-69-8
3,5-dimethylphenyl boronic acid

B: 182163-96-8
3,4,5-trimethoxyphenylboronic Acid

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 1016971-55-3
C26H31B3O9

A: 172975-69-8
3,5-dimethylphenyl boronic acid

B: 182163-96-8
3,4,5-trimethoxyphenylboronic Acid

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 34907-38-5
tris(3.5-dimethyl phenyl)boroxine

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With water at 25℃; Equilibrium constant;

: 34696-73-6
3,5-dimethyphenylmagnesium bromide

A: B,B-bis(3,5-dimethylphenyl)borinic acid

B: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With Triisopropyl borate In tetrahydrofuran at -55 - 20℃; Temperature;

: 95070-94-3
(3,5-dimethylphenyl)lithium

A: B,B-bis(3,5-dimethylphenyl)borinic acid

B: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With Triisopropyl borate In tetrahydrofuran at -70 - 20℃;

: C10H15BO2

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
With hydrogenchloride; water In tetrahydrofuran; hexane at 20℃; pH=3 - 5;
With hydrogenchloride; water In tetrahydrofuran	114.6 g

: 34696-73-6
3,5-dimethyphenylmagnesium bromide

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrahydrofuran / -78 - 20 °C 2: hydrogenchloride; water / tetrahydrofuran View Scheme

: 87-62-7
2,6-dimethylaniline

: 172975-69-8
3,5-dimethylphenyl boronic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: bromine / methanol / 20 °C 2.1: sulfuric acid / ethanol / 1 h / 7 - 20 °C 2.2: 1.5 h / 20 °C / Cooling 2.3: 20 °C / Inert atmosphere 3.1: magnesium / tetrahydrofuran / -78 - 20 °C View Scheme

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 246219-75-0
methyl (S)-2-[3-(2-benzyloxy-1-methylethyl)-2-iodo-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-methylpropanoate

: 246219-76-1
methyl (S)-2-[3-(2-benzyloxy-1-methylethyl)-2-(3,5-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-methylpropanoate

Conditions

Conditions	Yield
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In ethanol; toluene at 85℃; for 15h; Suzuki-Miayura cross-coupling;	100%

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 292600-31-8
(S)-1-(2-Azabicyclo[2.2.2]oct-2-yl)-2-[3-(2-benzyloxy-1-methylethyl)-2-iodo-1H-pyrrolo[2,3-c]pyridin-5-yl]-2-methyl propan-1-one

: 292600-32-9
(S)-1-(2-Azabicyclo[2.2.2]oct-2-yl)-2-[3-(2-benzyloxy-1-methylethyl)-2-(3,5-dimethylphenyl)-1H-pyrrolo[2,3-c]pyridin-5-yl]-2-methylpropan-1-one

Conditions

Conditions	Yield
With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In ethanol; toluene at 90℃; for 15h; Suzuki-Miayura cross-coupling;	100%

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 25570-02-9
3,3',5,5'-tetramethyl-1,1'-biphenyl

Conditions

Conditions	Yield
With air; palladium diacetate In methanol at 20℃;	100%
With potassium acetate; silver(l) oxide In methanol at 40℃; for 15h;	99%
With bromo-phenyl-acetic acid methyl ester; potassium fluoride; dichloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II) In 1,4-dioxane; water at 100℃; for 24h;	95%

: 628326-05-6
4-(4-bromo-2-formylphenyl)piperazine-1-carboxylic acid tert-butyl ester

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 628325-65-5
4-(3-formyl-3',5'-dimethylbiphenyl-4-yl)piperazine-1-carboxylic acid tert-butyl ester

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,2-dimethoxyethane Suzuki coupling; Heating;	100%

: 1147270-21-0
7-chloro-2-cyclohexylmethylindan-1-one

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1147270-27-6
7-(3',5'-dimethylphenyl)-2-cyclohexylmethylindan-1-one

Conditions

Conditions	Yield
With trisodium tris(3-sulfophenyl)phosphine; palladium diacetate; sodium carbonate In water; ethylene glycol at 125℃; for 4h; Inert atmosphere;	100%

: N-(2-(4-bromo-5-(4-(tert-butyl)phenyl)-3-phenylthiophen-2-yl)-2-(p-tolyl)ethyl)-4-methylbenzenesulfonamide

: 172975-69-8
3,5-dimethylphenyl boronic acid

: N-(2-(5-(4-(tert-butyl)phenyl)-4-(3,5-dimethylphenyl)-3-phenylthiophen-2-yl)-2-(p-tolyl)ethyl)-4-methylbenzenesulfonamide

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; sodium hydroxide; tri-t-butylphosphonium tetraphenylborate complex In tetrahydrofuran; water at 65℃; for 24h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;	100%

: 108-86-1
bromobenzene

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 17057-88-4
3,5-dimethylbiphenyl

Conditions

Conditions	Yield
With Pd/C; potassium carbonate In water; N,N-dimethyl-formamide at 40℃; for 5h; Suzuki Coupling;	99%
With potassium carbonate In ethanol; water at 80℃; for 7h; Suzuki Coupling;	90%
With tris-(o-tolyl)phosphine; microencapsulated Pd(PPh3) In acetonitrile for 6h; Heating;	83%
With potassium phosphate tribasic trihydrate In water at 80℃; for 15h; Suzuki-Miyaura Coupling; Green chemistry;	82%

: 78229-12-6
(Ra)-3,3’-dibromo-2,2’-dimethoxy-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaphthalene

: 172975-69-8
3,5-dimethylphenyl boronic acid

: (R)-3,3'-bis-(3,5-dimethylphenyl)-2,2'-dimethoxy-5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl

Conditions

Conditions	Yield
With potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); tricyclohexylphosphine In tetrahydrofuran at 75℃; for 22h;	99%
Stage #1: (Ra)-3,3’-dibromo-2,2’-dimethoxy-5,5’,6,6’,7,7’,8,8’-octahydro-1,1’-binaphthalene; tetrakis(triphenylphosphine) palladium(0) at 20℃; for 0.166667h; Suzuki coupling; Stage #2: 3,5-dimethylphenyl boronic acid With sodium carbonate In ethanol at 90℃; for 18h; Further stages.;	97%

: 106-38-7
para-bromotoluene

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 7383-87-1
1-(4-methylphenyl)-3,5-dimethylbenzene

Conditions

Conditions	Yield
With bis-(1-methylimidazole)palladium(II) dichloride; sodium hydroxide In water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Green chemistry;	99%
With sodium carbonate; 1,2-bis(2'-pyrazineethynyl)benzene palladium dichloride In water; acetonitrile at 70℃; for 6h; Suzuki coupling;	91%

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 591-19-5
3-bromoaniline

: 783325-73-5
3-amino-3',5'-dimethylbiphenyl

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine; cesium fluoride In tetrahydrofuran at 20℃; for 2h; Suzuki coupling;	99%
With cesium fluoride; tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine In tetrahydrofuran at 20℃; for 2h; Suzuki Coupling;	99%

: 91-56-5
indole-2,3-dione

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 3-(3',5'-dimethylphenyl)-3-hydroxy-1,3-dihydro-indol-2-one

Conditions

Conditions	Yield
With triphenyl phosphite; [(C2H4)2Rh(acac)] In acetone for 4h; Heating;	99%

: 18368-63-3
6-chloro-2-picoline

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 2-(3',5'-dimethylphenyl)-6-methylpyridine

Conditions

Conditions	Yield
With potassium phosphate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 16h; Suzuki-Miyaura coupling;	99%

: 910791-84-3
N-(5'-bromo-3'-phenylpyraz-2'-yl)pyridinium aminide

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1011793-95-5
N-[5-(3,5-dimethylphenyl)-3-phenylpyrazin-2-yl]pyridinium aminide

Conditions

Conditions	Yield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In ethanol; toluene for 8h; Suzuki coupling reaction; Heating;	99%

: 99-02-5
3'-Chloroacetophenone

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1-(3',5'-dimethylbiphenyl-3-yl)ethanone

Conditions

Conditions	Yield
With potassium phosphate; palladium diacetate In tetrahydrofuran at 100℃; for 24h; Suzuki-Miyaura coupling;	99%

: 591-50-4
iodobenzene

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 17057-88-4
3,5-dimethylbiphenyl

Conditions

Conditions	Yield
With palladium diacetate; sodium carbonate In water; acetone at 35℃; for 0.5h; Inert atmosphere;	99%
With bis-(1-methylimidazole)palladium(II) dichloride; sodium hydroxide In water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Green chemistry;	99%
With potassium carbonate In water at 80℃; for 1.5h; Suzuki Coupling; Green chemistry;	90%

: 130755-46-3
4,4'-dithiobis [5-amino-3-cyano-1-{2,6-dichloro-4-(trifluoromethyl)phenyl}-1H-pyrazole]

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1158997-64-8
C19H13Cl2F3N4S

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; oxygen In water; dimethyl sulfoxide at 100℃; for 36h;	99%

: C19H15NO4

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1204518-49-9
C27H25NO4

Conditions

Conditions	Yield
With C52H36F8O2Rh2 In 1,4-dioxane; water at 50℃; for 12h; optical yield given as %ee; enantioselective reaction;	99%

: 930-68-7
cyclohexenone

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1220531-61-2
(R)-3-(3,5-dimethyl-phenyl)cyclohexanone

Conditions

Conditions	Yield
With chlorobis(ethylene)rhodium(I) dimer; (R)-(6-(tert-butylsulfinyl)-2,3-dimethoxyphenyl)diphenylphosphine; potassium hydroxide In water; toluene at 20 - 40℃; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%
Stage #1: 3,5-dimethylphenyl boronic acid With chlorobis(ethylene)rhodium(I) dimer; C8H16N2O4S2 In 1,4-dioxane at 50℃; for 0.25h; Inert atmosphere; Stage #2: cyclohexenone With potassium hydroxide In 1,4-dioxane; methanol at 10℃; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%
With potassium fluoride; chlorobis(ethylene)rhodium(I) dimer; (R,Z)-1-(tert-butylsulfinyl)-2-(prop-1-enyl)benzene In methanol; water at 40℃; for 3h; Hayashi-Miyaura reaction; Inert atmosphere; optical yield given as %ee; stereoselective reaction;	99%

: 626-55-1
3-Bromopyridine

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 3,5-dimethyl-1-(3-pyridyl)benzene

Conditions

Conditions	Yield
With bis-(1-methylimidazole)palladium(II) dichloride; sodium hydroxide In water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Green chemistry;	99%
With sodium carbonate In methanol at 60℃; for 0.5h; Suzuki-Miyaura cross-coupling;	> 99 %Chromat.

: 99-90-1
para-bromoacetophenone

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 677022-27-4
1-(3’,5’-dimethylbiphenyl-4-yl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In water at 80℃; for 10h; Suzuki-Miyaura Coupling; Green chemistry;	99%
With potassium carbonate; palladium dichloride; 3,3'-dimethyl-1,1’-(1,3-phenylenedimethylene)-bis(1H-imidazolium) dichloride In water; N,N-dimethyl-formamide for 3h; Suzuki Coupling; Reflux;	97%
With sodium acetate In water; N,N-dimethyl-formamide for 12h; Suzuki coupling; Reflux;	94%

: 1262431-28-6
(E)-2-fluorovinyl 4-methylbenzenesulfonate

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1262431-30-0
(E)-1-(2-fluorovinyl)-3,5-dimethylbenzene

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium phosphate; tricyclohexylphosphine In 1,4-dioxane at 100℃; for 14h; Suzuki-Miyaura reaction; Inert atmosphere; stereoselective reaction;	99%

: 3179-10-0
1-methoxy-4-(2-nitro-vinyl)-benzene

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1-methoxy-4-(1-(3,5-dimethylphenyl)-2-nitroethyl)benzene

Conditions

Conditions	Yield
With chlorobis(ethylene)rhodium(I) dimer; tert-butanesulfinylphosphine; triethylamine In ethanol at 40℃; for 10h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 1207-69-8
9-Chloroacridine

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1352136-18-5
9-(3,5-dimethylphenyl)acridine

Conditions

Conditions	Yield
With potassium phosphate In toluene at 100℃; for 24h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;	99%
With potassium phosphate; palladium diacetate; tricyclohexylphosphine In water; toluene Reflux;

: 134-81-6
benzil

: 172975-69-8
3,5-dimethylphenyl boronic acid

: C22H20O2

Conditions

Conditions	Yield
With bis(ethylene)rhodium(I) chloride dimer; C19H23NOS; potassium hydroxide In 1,4-dioxane; water at 20 - 50℃; for 12h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 93-97-0
benzoic acid anhydride

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 13319-70-5
3,5-dimethylbenzophenone

Conditions

Conditions	Yield
With NHC-Pd(II)-Im; sodium hydrogencarbonate In water at 20℃; for 12h; Inert atmosphere;	99%
Stage #1: benzoic acid anhydride; 3,5-dimethylphenyl boronic acid With sodium hydrogencarbonate In water at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: With C19H25Br2N5Pd In water at 20℃; for 36h; Inert atmosphere;	86%

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 614-47-1
1,3-diphenyl-propen-3-one

: 1383843-81-9
(S)-3-(3, 5-dimethylphenyl)-1,3-diphenylpropan-1-one

Conditions

Conditions	Yield
With potassium fluoride; chlorobis(ethylene)rhodium(I) dimer; (R)-(6-(tert-butylsulfinyl)-2,3-dimethoxyphenyl)diphenylphosphine In water; isopropyl alcohol at 40℃; for 3h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 55379-09-4
3-butyl-1,2-benzisothiazole-1,1-dioxide

: 172975-69-8
3,5-dimethylphenyl boronic acid

: (R)-3-butyl-3-(3,5-dimethylphenyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide

Conditions

Conditions	Yield
With palladium(II) trifluoroacetate; (S)-methyl 6-(4-(tert-butyl)-4,5-dihydrooxazol-2-yl)nicotinate; oxygen In 2,2,2-trifluoroethanol at 40℃; for 12h; enantioselective reaction;	99%

: 4122-56-9
methyl o-formylbenzoate

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 1227504-98-4
(S)-3-(3,5-dimethylphenyl)-1,3-dihydro-2-benzofuran-1-one

Conditions

Conditions	Yield
With (R)-Me-BIPAM; tris(triphenylphosphine)ruthenium(II) chloride; potassium carbonate In water; toluene at 50℃; for 18h; Inert atmosphere; enantioselective reaction;	99%

: 2-methylbenzyl carbamate

: 172975-69-8
3,5-dimethylphenyl boronic acid

: C16H18

Conditions

Conditions	Yield
With NHC-Pd(II)-Im; lithium tert-butoxide In water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; Green chemistry;	99%

: 16605-27-9
3-methylbenzyl N,N-dimethylcarbamate

: 172975-69-8
3,5-dimethylphenyl boronic acid

: 16134-73-9
3,3',5-Trimethyl-diphenylmethan

Conditions

Conditions	Yield
With NHC-Pd(II)-Im; lithium tert-butoxide In water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; Green chemistry;	99%

3,5-Dimethylphenylboronic acid Chemical Properties

MF: C₈H₁₁BO₂
Synonyms: RARECHEM AH PB 0186;M-XYLENE-5-BORONIC ACID;TIMTEC-BB SBB004076;3,5-DIMETHYLBenzeneBORONIC ACID;3,5-DIMETHYLPHENYLBORONIC ACID;AKOS BRN-0067;3,5-Dimethyl Benzene;3,5-DIMETHYLBenzeneBORONIC ACID 98%
MW: 149.98
mp: 261-265 °C(lit.)
storage temp.: 0-6°C
BRN : 7368658

3,5-Dimethylphenylboronic acid Safety Profile

Risk Statements : R36/37/38:Irritating to eyes, respiratory system and skin.;
Safety Statements : S26:In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice.;
S37/39:Wear suitable gloves and eye/face protection.;
Hazard Codes : Xn,Xi
WGK Germany : 3
Hazard Note : Irritant

Product Name

3,5-Dimethylphenylboronic acid

Synthetic route

3,5-Dimethylphenylboronic acid Chemical Properties

3,5-Dimethylphenylboronic acid Safety Profile

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