3-Methyl-3-oxetanemethanol supplier

Name
3-Methyl-3-oxetanemethanol
EINECS -0
CAS No. 3143-02-0
Article Data16
CAS DataBase
Density 1.031 g/cm³
Solubility
Melting Point
Formula C₅H₁₀O₂
Boiling Point 152.2 °C at 760 mmHg
Molecular Weight 102.133
Flash Point 98.9 °C
Transport Information
Appearance clear colorless to pale yellow liquid
Safety 23-24/25-36/37
Risk Codes 43
Molecular Structure
Hazard Symbols Xi
Synonyms (3-Methyloxetan-3-yl)methanol;3-(Hydroxymethyl)-3-methyloxetane;3-Methyl-3-(hydroxymethyl)oxacyclobutane;3-Methyl-3-(hydroxymethyl)oxetane;3-Methyl-3-oxetanylmethyl alcohol;MOXA(monomer);3-Hydroxymethyl-3-methyloxetane;
PSA 29.46000
LogP 0.01520

Synthetic route

: 1620017-21-1
tert-butyl[(3-methyloxetan-3-yl)methoxy]diphenylsilane

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h;	84%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h;	84%

: 77-85-0
2-(hydroxymethyl)-2-methylpropane-1,3-diol

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
With potassium hydroxide; Diethyl carbonate at 115℃; for 1h;	83.7%
With potassium hydroxide; Diethyl carbonate In ethanol for 2h; Heating;	81%
Stage #1: 2-(hydroxymethyl)-2-methylpropane-1,3-diol With potassium hydroxide; carbonic acid dimethyl ester In methanol under 760.051 Torr; Heating; Stage #2: at 130 - 140℃; under 110 - 120 Torr;	77%

: 84051-79-6
1,1,1-Trimethylolethane dinitrate

A: 3143-02-0
3-hydroxymethyl-3-methyloxethane

B: 77-85-0
2-(hydroxymethyl)-2-methylpropane-1,3-diol

C: 625-58-1
ethyl nitrate

D: 84051-80-9
1,1,1-Trimethylolethane mononitrate

E: 84051-81-0
3-methyl-3-(nitroxymethyl)oxetane

F NO2- (5.2percent), NO3-: NO2- (5.2percent), NO3-

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 55℃; for 3.10833h; Product distribution; Rate constant; var. NaOH conc.;	A 13% B 0.7% C n/a D 24% E 66% F n/a

...Expand

: 3032-55-1
trimethylolethane trinitrate

A: 3143-02-0
3-hydroxymethyl-3-methyloxethane

B: 77-85-0
2-(hydroxymethyl)-2-methylpropane-1,3-diol

C: 84051-80-9
1,1,1-Trimethylolethane mononitrate

D: 84051-79-6
1,1,1-Trimethylolethane dinitrate

E: 84051-81-0
3-methyl-3-(nitroxymethyl)oxetane

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 55℃; for 86.1667h; Product distribution; Rate constant; Thermodynamic data; var. NaOH conc., var. solv., solv. effect, ΔH(excit.), ΔF(excit.), ΔS(excit.);	A 45.5% B 2.3% C 31.8% D 1.5% E 16.5%

...Expand

: 2210-03-9
2-(bromomethyl)-2-methylpropane-1,3-diol

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
With Ph4SbOMe In 1,2-dichloro-ethane at 60℃; for 24h; sealed ampule;	82 % Chromat.

: 77-85-0
2-(hydroxymethyl)-2-methylpropane-1,3-diol

: 105-58-8
Diethyl carbonate

ethanolic KOH-solution: ethanolic KOH-solution

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
Erhitzen des Reaktionsprodukts unter vermindertem Druck bis auf 200grad;

...Expand

: 84051-80-9
1,1,1-Trimethylolethane mononitrate

A: 3143-02-0
3-hydroxymethyl-3-methyloxethane

B: 625-58-1
ethyl nitrate

C NO2-, NO3-: NO2-, NO3-

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 55℃; for 21.9033h; Product distribution; Rate constant; var. NaOH conc.;

...Expand

: 84051-81-0
3-methyl-3-(nitroxymethyl)oxetane

A: 3143-02-0
3-hydroxymethyl-3-methyloxethane

B: 625-58-1
ethyl nitrate

C NO2-, NO3-: NO2-, NO3-

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 55℃; for 11.38h; Product distribution; Rate constant; var. NaOH conc.;

...Expand

: 77-85-0
2-(hydroxymethyl)-2-methylpropane-1,3-diol

: 105-58-8
Diethyl carbonate

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
With potassium hydroxide In ethanol

: 1256651-65-6
N-hexyl-3-methyloxetane-3-carboxamide

A: 3143-02-0
3-hydroxymethyl-3-methyloxethane

B: 111-26-2
hexan-1-amine

Conditions

Conditions	Yield
With [RuH(CO)(BPy-tPNN*)]; hydrogen In tetrahydrofuran at 110℃; under 7600.51 Torr; for 48h; Fischer-Porter tube;	A 74 %Chromat. B 74 %Chromat.

: 72999-08-7
2-(hydroxymethyl)-2-methylpropanedioic acid diethyl ester

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 20 °C / Inert atmosphere 2.1: lithium borohydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 3.2: 1 h / Cooling with ice 3.3: 4.17 h / 0 - 60 °C 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme
Multi-step reaction with 4 steps 1.1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 20 °C / Inert atmosphere 2.1: lithium borohydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 3.2: Cooling with ice 3.3: 4.17 h / 60 °C / Cooling with ice 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme

: 1620017-20-0
diethyl 2-[(tert-butyldiphenylsilyloxy)methyl]-2-methylmalonate

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: lithium borohydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 2.2: 1 h / Cooling with ice 2.3: 4.17 h / 0 - 60 °C 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme
Multi-step reaction with 3 steps 1.1: lithium borohydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 2.2: Cooling with ice 2.3: 4.17 h / 60 °C / Cooling with ice 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme

: 2-((tert-butyl-diphenyl-silanyloxy)methyl)-2-methyl-propane-1,3-diol

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 1.2: 1 h / Cooling with ice 1.3: 4.17 h / 0 - 60 °C 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C 1.2: Cooling with ice 1.3: 4.17 h / 60 °C / Cooling with ice 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C View Scheme

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 122-04-3
4-nitro-benzoyl chloride

: 140635-77-4
(3-methyloxetan-3-yl)methyl 4-nitrobenzoate

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 20℃; for 0.333333h;	100%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 98-59-9
p-toluenesulfonyl chloride

: 99314-44-0
(3-methyloxetan-3-yl)methyl 4-methylbenzenesulfonate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃; for 12h; Inert atmosphere;	100%
With pyridine for 1.5h; Inert atmosphere; Cooling with ice;	96%
With 1-methyl-1H-imidazole; triethylamine In dichloromethane at 25℃; for 2h;	95%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 7432-21-5
N-carbobenzyloxy-L-tryptophane

: 127130-93-2
N-(benzyloxycarbonyl)-L-tryptophane (3-methyl-3-oxetanyl)methyl ester

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃;	100%
With dmap; dicyclohexyl-carbodiimide In diethyl ether at 25℃; for 0.25h;	84%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 33332-28-4
2-amino-6-chloropyrazine

: 1431654-81-7
6-((3-methyloxetan-3-yl)methoxy)pyrazin-2-amine

Conditions

Conditions	Yield
Stage #1: 3-hydroxymethyl-3-methyloxethane With sodium hydride In 1,4-dioxane; mineral oil at 20℃; for 2h; Stage #2: 2-amino-6-chloropyrazine for 16h; Reflux;	100%
Stage #1: 3-hydroxymethyl-3-methyloxethane With sodium hydride In 1,4-dioxane; mineral oil at 20℃; for 2h; Stage #2: 2-amino-6-chloropyrazine In 1,4-dioxane; mineral oil for 16h; Reflux;	100%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 3-methyl-3-oxetane carboxylic acid

Conditions

Conditions	Yield
With dipyridinium dichromate In N,N-dimethyl-formamide at 20℃;	100%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene In water; acetonitrile at 20℃;	14 g
In water; acetonitrile at 20℃; Cooling with ice;	14 g

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 3-[4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-yl]propionic acid

: 5,5-difluoro-7,9-dimethyl-3-(3-((3-methyloxetan-3-yl)methoxy)-3-oxopropyl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;	100%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 78385-26-9
3-bromomethyl-3-methyloxetane

Conditions

Conditions	Yield
With carbon tetrabromide; triphenylphosphine In dichloromethane for 0.333333h; Ambient temperature;	99%
With carbon tetrabromide; triphenylphosphine In dichloromethane at 0 - 20℃; for 0.333333h; Product distribution / selectivity;	95%
With triphenyl phosphite; N-Bromosuccinimide In dichloromethane Ambient temperature;	74%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 141-75-3
butyryl chloride

: 173729-55-0
butyric acid 3-methyloxetan-3-ylmethyl ester

Conditions

Conditions	Yield
With pyridine In dichloromethane	99%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 4635-59-0
4-Chlorobutanoyl chloride

: 137265-74-8
3-methyl-3-oxetanylmethyl 4-chlorobutanoate

Conditions

Conditions	Yield
With triethylamine In diethyl ether for 1h; Ambient temperature;	98%
With pyridine In dichloromethane at 0℃; for 48h;	92%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 434-13-9
Lithocholic acid

: (R)-(3-methyloxetan-3-yl)methyl 4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;	98%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 50733-91-0
7-bromoheptanoyl chloride

: 129884-26-0
1-methyl-3-oxacyclobutanecarbinyl 7-bromoheptanoate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0℃; for 1.5h;	97%
With pyridine In tetrahydrofuran at 5℃; for 1.5h;	89%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 75-36-5
acetyl chloride

: 117471-37-1
(3-Methyloxetan-3-yl)methyl acetate

Conditions

Conditions	Yield
With pyridine In dichloromethane	97%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 107188-91-0
5-bromo-2,3-dimethoxybenzoic acid chloride

: 259814-04-5
3-methyloxetane-3-methyl 2,3-dimethoxy-5-bromobenzoate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃;	97%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 53293-00-8
hex-5-ynoic acid

: 89276-33-5
(3-methyloxyethan-3-yl)methyl-5-hexynoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 1h; Cooling with ice;	97%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 0.75h;

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 768-33-2
phenyldimethylsilyl chloride

: 1269424-51-2
3-methyl-3-[(phenyldimethylsilyl)oxymethyl]oxetane

Conditions

Conditions	Yield
Stage #1: 3-hydroxymethyl-3-methyloxethane With sodium hydride In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere; Stage #2: phenyldimethylsilyl chloride In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere;	97%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 2210-03-9
2-(bromomethyl)-2-methylpropane-1,3-diol

Conditions

Conditions	Yield
With hydrogen bromide In tetrahydrofuran; water at 20℃; for 17.5h; Inert atmosphere; Cooling with ice;	96.1%
With hydrogen bromide In tetrahydrofuran at 0 - 20℃; for 5h;	96%
With hydrogen bromide In tetrahydrofuran at 0℃; for 4h;	93.7%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 3128-06-1
5-ketohexanoic acid

: 264601-56-1
3-methyloxetan-3-yl-carbinyl 5-oxohexanoate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 12h;	96%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 18162-48-6
tert-butyldimethylsilyl chloride

: tert-butyldimethyl((3-methyloxetan-3-yl)methoxy)silane

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 6h;	96%
With 1H-imidazole In N,N-dimethyl-formamide at 20 - 25℃; for 12h;	84%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 7154-66-7
2-bromobenzoic acid chloride

: (3-methyloxetan-3-yl)methyl 2-bromobenzoate

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;	96%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: tert-butyl 2-(4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)acetate

: tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-(3-methyloxetan-3-yl)prop-2-enoate

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.25h;	96%

: 123-91-1
1,4-dioxane

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 10035-10-6, 12258-64-9
hydrogen bromide

: 2210-03-9
2-(bromomethyl)-2-methylpropane-1,3-diol

Conditions

Conditions	Yield
In water for 3.5h; Inert atmosphere; Schlenk technique; Reflux;	96%

...Expand

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 65-85-0
benzoic acid

: 173729-57-2
(3-Methyloxetan-3-yl)methyl benzoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;	96%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 4-(N-((1-(((1,1,1,3,3,3-hexafluoropropan-2-yl)oxy)carbonyl)piperidin-4-yl)methyl)sulfamoyl)benzoic acid

: 1,1,1,3,3,3-hexafluoropropan-2-yl 4-((4-(((3-methyloxetan-3 yl)methoxy)carbonyl) phenylsulfonamido) methyl)piperidine-1-carboxylate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 0.25h; Inert atmosphere;	96%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 30379-55-6
benzyloxyacetic acid

: (3-methyloxetan-3-yl)methyl 2-(benzyloxy)acetate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 25℃; for 18h; Inert atmosphere;	96%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;	94%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 66493-39-8
4-(N-tert-butoxycarbonyl)aminobenzoic acid

: (3-methyloxetan-3-yl)methyl 4-((tert-butoxycarbonyl)amino)benzoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;	96%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 6214-35-3
(Z)-3-iodoprop-2-enoic acid

: 339177-46-7
(3-methyl-3-oxetanyl)methyl (Z)-3-iodo-2-propenoate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃;	95%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h;	95%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 246862-22-6
3-[(2,4,6-triisopropylphenyl)sulfenyl]propionic acid

: 246862-23-7
(3-methyl-3-oxethanyl)methyl 3-[(2,4,6-triisopropylphenyl)sulfenyl]propionate

Conditions

Conditions	Yield
With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 36h;	95%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 187283-45-0
(S)-3-((tert-butyldimethylsilyl)oxy)-4,4-dimethyl-5-oxoheptanoic acid

: 823789-77-1
(-)-(3S)-3-(tert-butyldimethylsilyloxy)-4,4-dimethyl-5-oxoheptanoic acid 3-methyloxetan-3-ylmethyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h;	95%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 84051-81-0
3-methyl-3-(nitroxymethyl)oxetane

Conditions

Conditions	Yield
With carbon dioxide; dinitrogen pentoxide at 0℃; under 45004.5 - 60006 Torr; for 0.5h; Autoclave;	95%

: 3143-02-0
3-hydroxymethyl-3-methyloxethane

: 105-53-3
diethyl malonate

: ethyl ((3-methyloxetan-3-yl)methyl)propanedioate

Conditions

Conditions	Yield
at 150℃; for 48h;	95%
at 150℃; for 48h;	95%

3-Methyl-3-oxetanemethanol Specification

The 3-Methyl-3-oxetanemethanol, with the CAS registry number 3143-02-0, is also known as 3-Hydroxymethyl-3-methyloxetane. It belongs to the product categories of Oxetanes; Simple 4-Membered Ring Compounds. This chemical's molecular formula is C₅H₁₀O₂ and molecular weight is 102.13. Its IUPAC name is called (3-methyloxetan-3-yl)methanol. The product should be sealed at temperature of 2-8 °C.

Physical properties of 3-Methyl-3-oxetanemethanol: (1)ACD/LogP: -0.61; (2)ACD/LogD (pH 5.5): -0.61; (3)ACD/LogD (pH 7.4): -0.61; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 11.04; (7)ACD/KOC (pH 7.4): 11.04; (8)#H bond acceptors: 2; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 2; (11)Index of Refraction: 1.443; (12)Molar Refractivity: 26.28 cm³; (13)Molar Volume: 99 cm³; (14)Surface Tension: 40.3 dyne/cm; (15)Density: 1.031 g/cm³; (16)Flash Point: 98.9 °C; (17)Enthalpy of Vaporization: 45.31 kJ/mol; (18)Boiling Point: 152.2 °C at 760 mmHg; (19)Vapour Pressure: 1.32 mmHg at 25°C.

Preparation: this chemical can be prepared by 2-hydroxymethyl-2-methyl-propane-1,3-diol. This reaction will need reagent diethyl carbonate, ethanolic KOH-solution. The reaction temperature is 180 °C.

Uses of 3-Methyl-3-oxetanemethanol: it can be used to produce 2-(dimethylamino-methyl)-2-methyl-propane-1,3-diol at temperature of 180 °C. This reaction will need solvent H₂O.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It also may cause sensitisation by skin contact. You must avoid contacting it with skin and eyes. Whenever you will contact it, please wear suitable protective clothing and gloves.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC1(COC1)CO
(2)InChI: InChI=1S/C5H10O2/c1-5(2-6)3-7-4-5/h6H,2-4H2,1H3
(3)InChIKey: NLQMSBJFLQPLIJ-UHFFFAOYSA-N

Product Name

3-Methyl-3-oxetanemethanol

Synthetic route

3-Methyl-3-oxetanemethanol Specification

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