Product Name

  • Name

    Cyclohexyldiphenylphosphine

  • EINECS 228-904-2
  • CAS No. 6372-42-5
  • Article Data30
  • CAS DataBase
  • Density
  • Solubility Insoluble in water
  • Melting Point 58-62 ºC
  • Formula C18H21 P
  • Boiling Point 374 °C at 760 mmHg
  • Molecular Weight 268.338
  • Flash Point 189.4 °C
  • Transport Information
  • Appearance white to light yellow crystal powder
  • Safety S24/25
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 6372-42-5 (Cyclohexyldiphenylphosphine)
  • Hazard Symbols
  • Synonyms Cyclohexyldiphenylphosphine;Diphenylcyclohexylphosphine
  • PSA 13.59000
  • LogP 4.45200

Synthetic route

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate

1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With N,N,N',N'',N'''-pentamethyldiethylenetriamine; zinc In N,N-dimethyl-formamide at 20℃; for 12h; Reagent/catalyst; Time;95%
(cyclohexyl)diphenylphosphane oxide
13689-20-8

(cyclohexyl)diphenylphosphane oxide

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With copper(II) trifluoromethanesulfonate; 1,1,3,3-Tetramethyldisiloxane In toluene at 100℃; Inert atmosphere;86%
With oxalyl dichloride; hydrogen In chloroform-d1 at 130℃; under 60006 Torr; for 18h; Reagent/catalyst;85%
With copper(II) bis(trifluoromethanesulfonate); 1,1,3,3-tetramethyldisilazane In toluene at 80℃;82%
cyclohexyl chloride
542-18-7

cyclohexyl chloride

sodium diphenylphosphide
4376-01-6

sodium diphenylphosphide

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In tetrahydrofuran at 25℃; for 2h; Inert atmosphere;73%
1-iodocyclohexane
626-62-0

1-iodocyclohexane

diphenylphosphane
829-85-6

diphenylphosphane

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1,3-dicyano-5-fluoro-2,4,6-tris(diphenylamino)benzene; N-ethyl-N,N-diisopropylamine In acetonitrile for 24h; Inert atmosphere; Glovebox; Sealed tube; Irradiation;73%
1-bromocyclohexane
108-85-0

1-bromocyclohexane

triphenylphosphine
603-35-0

triphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
Stage #1: triphenylphosphine In tetrahydrofuran at 20℃; Inert atmosphere;
Stage #2: 1-bromocyclohexane In tetrahydrofuran for 0.166667h; Inert atmosphere;
70%
With ammonia; sodium 2.) irradiation, 30 min; Multistep reaction;
ammonium hydroxide
1336-21-6

ammonium hydroxide

cyclohexylmagnesiumchloride
931-51-1

cyclohexylmagnesiumchloride

Dichlorophenylphosphine
644-97-3

Dichlorophenylphosphine

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With hydrogenchloride In water70%
cyclohexyl chloride
542-18-7

cyclohexyl chloride

triphenylphosphine
603-35-0

triphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With ammonia; sodium 2.) irradiation, 180 min; Multistep reaction;
triphenylphosphine
603-35-0

triphenylphosphine

A

dicyclohexylphenylphosphine
6476-37-5

dicyclohexylphenylphosphine

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C

tricyclohexylphosphine
2622-14-2

tricyclohexylphosphine

Conditions
ConditionsYield
With n-butyllithium; hydrogen; bis(2,6-diisopropylphenoxy) trichloroniobium(V) In hexane; benzene at 60℃; under 62057.8 Torr; Kinetics; var. of catalyst;
With n-butyllithium; hydrogen; In hexane; benzene at 60℃; under 62057.8 Torr;
dicyclohexylzinc(II)
15658-08-9

dicyclohexylzinc(II)

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In tetrahydrofuran at 0℃; for 1h;
1-bromocyclohexane
108-85-0

1-bromocyclohexane

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With pyridine; tris-(trimethylsilyl)silane; 1,1'-azobis(1-cyanocyclohexanenitrile) In benzene for 20h; Heating;
Stage #1: 1-bromocyclohexane; chloro-diphenylphosphine With manganese; CpCr[(XylNCMe)2CH]; lead(II) bromide In tetrahydrofuran at 25℃; for 28h;
Stage #2:
92 %Spectr.
1H-imidazole-1-carbothioic acid O-cyclohexyl ester
131379-54-9

1H-imidazole-1-carbothioic acid O-cyclohexyl ester

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With tris-(trimethylsilyl)silane; triethylamine; 1,1'-azobis(1-cyanocyclohexanenitrile) In benzene for 18h; Heating;
C18H21P*H(1+)*BF4(1-)

C18H21P*H(1+)*BF4(1-)

Dimethyl(phenyl)phosphine
672-66-2

Dimethyl(phenyl)phosphine

A

C8H11P*H(1+)*BF4(1-)

C8H11P*H(1+)*BF4(1-)

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In dichloromethane-d2 at 20℃; Equilibrium constant;
C18H21P*H(1+)*BF4(1-)

C18H21P*H(1+)*BF4(1-)

(dibutyl)(phenyl)phosphine
6372-44-7

(dibutyl)(phenyl)phosphine

A

C14H23P*BF4(1-)*H(1+)

C14H23P*BF4(1-)*H(1+)

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In dichloromethane-d2 at 20℃; Equilibrium constant;
C18H21P*H(1+)*BF4(1-)

C18H21P*H(1+)*BF4(1-)

diphenyl(methyl)phosphine
1486-28-8

diphenyl(methyl)phosphine

A

C13H13P*BF4(1-)*H(1+)

C13H13P*BF4(1-)*H(1+)

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In dichloromethane-d2 at 20℃; Equilibrium constant;
C18H21P*H(1+)*BF4(1-)

C18H21P*H(1+)*BF4(1-)

ethyl-diphenyl-phosphane
607-01-2

ethyl-diphenyl-phosphane

A

C14H15P*BF4(1-)*H(1+)

C14H15P*BF4(1-)*H(1+)

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In dichloromethane-d2 at 20℃; Equilibrium constant;
C18H21P*H(1+)*BF4(1-)

C18H21P*H(1+)*BF4(1-)

Tri(p-tolyl)phosphine
1038-95-5

Tri(p-tolyl)phosphine

A

triphenylphosphine

triphenylphosphine

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In dichloromethane-d2 at 20℃; Equilibrium constant;
cyclohexanol
108-93-0

cyclohexanol

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran / 72 h / 20 °C
2: Et3N; tris(trimethylsilyl)silane; 1,1'-azobis(cyclohexane-1-carbonitrile) / benzene / 18 h / Heating
View Scheme
1-iodocyclohexane
626-62-0

1-iodocyclohexane

(trimethylsilyl)diphenylphosphine
17154-34-6

(trimethylsilyl)diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1,1'-azobis(cyclohexane)-1-carbonitrile In n-heptane at 100℃; for 72h;
1-iodocyclohexane
626-62-0

1-iodocyclohexane

(trimethylstannyl)diphenylphosphine
1213-51-0

(trimethylstannyl)diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1,1'-azobis(cyclohexane)-1-carbonitrile In benzene at 80℃; for 16h;
1H-imidazole-1-carbothioic acid O-cyclohexyl ester
131379-54-9

1H-imidazole-1-carbothioic acid O-cyclohexyl ester

(trimethylsilyl)diphenylphosphine
17154-34-6

(trimethylsilyl)diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1,1'-azobis(cyclohexane)-1-carbonitrile In n-heptane at 100℃; for 72h;
1H-imidazole-1-carbothioic acid O-cyclohexyl ester
131379-54-9

1H-imidazole-1-carbothioic acid O-cyclohexyl ester

(trimethylstannyl)diphenylphosphine
1213-51-0

(trimethylstannyl)diphenylphosphine

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1,1'-azobis(cyclohexane)-1-carbonitrile In benzene at 80℃; for 16h;
1-bromocyclohexane
108-85-0

1-bromocyclohexane

Tetraphenyldiphosphin
1101-41-3

Tetraphenyldiphosphin

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With Ti(N[t-Bu](3,5-Me2C6H3))3 In benzene at 20℃; Inert atmosphere;> 95 %Spectr.
Stage #1: 1-bromocyclohexane; Tetraphenyldiphosphin With manganese; CpCr[DppNC(Me)CHC(Me)NTol]; lead(II) bromide In tetrahydrofuran at 25℃; for 28h;
Stage #2:
70 %Spectr.
cyclohexyl chloride
542-18-7

cyclohexyl chloride

Tetraphenyldiphosphin
1101-41-3

Tetraphenyldiphosphin

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
Stage #1: cyclohexyl chloride; Tetraphenyldiphosphin With manganese; CpCr[(XylNCMe)2CH]; lead(II) bromide In tetrahydrofuran at 55℃; for 312h;
Stage #2:
81 %Spectr.
CpCr[DppNC(Me)CHC(Me)NTol](Cy)
1403767-43-0

CpCr[DppNC(Me)CHC(Me)NTol](Cy)

Tetraphenyldiphosphin
1101-41-3

Tetraphenyldiphosphin

A

C29H36BrCrN2
1403767-41-8

C29H36BrCrN2

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1-bromocyclohexane In benzene at 20℃;A n/a
B 96 %Spectr.
1-bromocyclohexane
108-85-0

1-bromocyclohexane

diphenylphosphane
829-85-6

diphenylphosphane

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
Stage #1: 1-bromocyclohexane; diphenylphosphane With manganese; CpCr[(XylNCMe)2CH]; lead(II) bromide In tetrahydrofuran at 25℃; for 28h;
Stage #2:
83 %Spectr.
CpCr[DppNC(Me)CHC(Me)NTol](Cy)
1403767-43-0

CpCr[DppNC(Me)CHC(Me)NTol](Cy)

diphenylphosphane
829-85-6

diphenylphosphane

A

C29H36BrCrN2
1403767-41-8

C29H36BrCrN2

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With 1-bromocyclohexane In benzene at 20℃;A n/a
B 30 %Spectr.
CpCr[DppNC(Me)CHC(Me)NTol](Cy)
1403767-43-0

CpCr[DppNC(Me)CHC(Me)NTol](Cy)

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

A

[(cyclopentadienyl)Cr(III)Cl(2,6-(Me2CH)2C6H3NC(Me)CH(Me)NC6H4Me)]
1262528-70-0

[(cyclopentadienyl)Cr(III)Cl(2,6-(Me2CH)2C6H3NC(Me)CH(Me)NC6H4Me)]

B

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In benzene at 20℃;A n/a
B 94 %Spectr.
chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

cyclohexylmagnesium bromide
931-50-0

cyclohexylmagnesium bromide

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃;
diphenylphosphane
829-85-6

diphenylphosphane

cyclohexene
110-83-8

cyclohexene

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

Conditions
ConditionsYield
With [κ5-N,N,N,N,C-(Me3SiNCH2CH2)2NCH2CH2NSiMe2CH2]Zr In benzene-d6 at 20℃; for 72h; UV-irradiation;
With C34H64N4Si4Sm In neat (no solvent) at 90℃; for 168h; Temperature; Inert atmosphere; Sealed tube; chemoselective reaction;
cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

(cyclohexyl)diphenylphosphane oxide
13689-20-8

(cyclohexyl)diphenylphosphane oxide

Conditions
ConditionsYield
With water; Selectfluor In acetonitrile at 20℃; for 0.166667h;99%
With 4-phenylthioxanthone In methanol at 20℃; under 760.051 Torr; for 1.33333h; Irradiation;99%
With dihydrogen peroxide Yield given;
[WI2(CO)(NCMe)(η(2)-MeC2Me)2]
111187-48-5

[WI2(CO)(NCMe)(η(2)-MeC2Me)2]

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

bis(PPh2Cy)(η2-but-2-yne)carbonyldi-iodotungsten
123863-47-8

bis(PPh2Cy)(η2-but-2-yne)carbonyldi-iodotungsten

Conditions
ConditionsYield
In dichloromethane N2 atmosphere; addn. of PPh2(C6H11) to soln. of W-complex (stirring), stirring (3 days), filtration; removal of solvent (vac.), recrystn. (CH2Cl2); elem. anal.;98%
hydrogen tetrachloroaurate(III) tetrahydrate

hydrogen tetrachloroaurate(III) tetrahydrate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

(diphenylcyclohexylphosphine)gold(I) chloride
209847-83-6

(diphenylcyclohexylphosphine)gold(I) chloride

Conditions
ConditionsYield
Stage #1: hydrogen tetrachloroaurate(III) tetrahydrate With propyl sulfide In ethanol at 40℃; for 0.166667h;
Stage #2: cyclohexyldiphenylphosphine In ethanol at 40℃; for 1h;
95%
silver hexafluoroantimonate

silver hexafluoroantimonate

rac.-[Ru(η6:η1-2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl)Cl2]
863615-26-3, 568592-59-6

rac.-[Ru(η6:η1-2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl)Cl2]

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[anti-Ru(η6:η1-2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl)(PCyPh2)Cl]SbF6

[anti-Ru(η6:η1-2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl)(PCyPh2)Cl]SbF6

Conditions
ConditionsYield
In dichloromethane byproducts: AgCl; under N2; CH2Cl2 added to mixt. of Ru complex, AgSbF6 and phosphine, mixt. stirred in the dark; monitoring by NMR; filtration through Celite, filtrate evapd. under vac., crystn. on slow diffusion of Et2O into CH2Cl2 soln.; elem. anal.;94%
2-(2'-pyridyl)benzoxazole
32959-62-9

2-(2'-pyridyl)benzoxazole

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C30H29CuIN2OP

C30H29CuIN2OP

Conditions
ConditionsYield
With copper(l) iodide In dichloromethane; acetonitrile94%
2-chloromethyl-1-methyl-1H-benzimidazole
4760-35-4

2-chloromethyl-1-methyl-1H-benzimidazole

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C27H30N2P(1+)*Cl(1-)

C27H30N2P(1+)*Cl(1-)

Conditions
ConditionsYield
In 1,4-dioxane at 100℃;93%
nickel(II) chloride hexahydrate

nickel(II) chloride hexahydrate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

bis(cyclohexyldiphenylphosphine)nickel(II) chloride
34090-21-6

bis(cyclohexyldiphenylphosphine)nickel(II) chloride

Conditions
ConditionsYield
In ethanol at 80℃; for 1h; Sealed tube; Inert atmosphere;92%
bis(acetonitrile)(acetylacetonate)palladium(II) tetrafluoroborate

bis(acetonitrile)(acetylacetonate)palladium(II) tetrafluoroborate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

(acetylacetonate-κ2O,O')bis[cyclohexyl(diphenyl)phosphine-κP]palladium(II) tetrafluoroborate

(acetylacetonate-κ2O,O')bis[cyclohexyl(diphenyl)phosphine-κP]palladium(II) tetrafluoroborate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 1.5h;90.6%
dimethylsulfide borane complex
13292-87-0

dimethylsulfide borane complex

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

diphenylcyclohexylphosphine-borane complex
127686-90-2

diphenylcyclohexylphosphine-borane complex

Conditions
ConditionsYield
In dichloromethane at 20℃; for 20h; Inert atmosphere; Schlenk technique;90%
rhodium(II) acetate dimer

rhodium(II) acetate dimer

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C44H54O8P2Rh2

C44H54O8P2Rh2

Conditions
ConditionsYield
In 1,2-dimethoxyethane; water at 20℃; for 0.5h; Schlenk technique; Inert atmosphere;90%
[Fe2(CO)6{μ-SCH2CH(CH2O2CCH3)S}]

[Fe2(CO)6{μ-SCH2CH(CH2O2CCH3)S}]

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C28H29Fe2O7PS2

C28H29Fe2O7PS2

Conditions
ConditionsYield
With trimethylamine-N-oxide In dichloromethane; acetonitrile at 20℃; for 1h;90%
1-bromo-butane
109-65-9

1-bromo-butane

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

n-butyl cyclohexyl phenyl phosphine
1143504-32-8

n-butyl cyclohexyl phenyl phosphine

Conditions
ConditionsYield
Stage #1: cyclohexyldiphenylphosphine In tetrahydrofuran at 20℃; for 6h; Inert atmosphere;
Stage #2: 1-bromo-butane In tetrahydrofuran for 0.5h; Inert atmosphere;
89%
silver perchlorate

silver perchlorate

thiosemicarbazide
79-19-6

thiosemicarbazide

acetone
67-64-1

acetone

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[Ag2(diphenylcyclohexylphosphine)2(2-(propan-2-ylidene)hydrazinecarbothioamide)2]*(ClO4)2

[Ag2(diphenylcyclohexylphosphine)2(2-(propan-2-ylidene)hydrazinecarbothioamide)2]*(ClO4)2

Conditions
ConditionsYield
Stage #1: silver perchlorate; thiosemicarbazide; acetone In acetonitrile at 50℃; for 1h;
Stage #2: cyclohexyldiphenylphosphine In chloroform; acetonitrile for 0.5h;
88%
cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

cobalt(II) chloride
7646-79-9

cobalt(II) chloride

[CoCl2(cyclohexyldiphenylphosphine)2]
648430-08-4

[CoCl2(cyclohexyldiphenylphosphine)2]

Conditions
ConditionsYield
In ethanol soln. of phosphine in ethanol was added to soln. of CoCl2 in ethanol; mixt. was stirred for 24 h; filtered; washed (ethanol, pentane); dried in vac.; extd. (Soxhlet, boiling pentane, several d); soln. removed; residue dried (vac.); elem. anal.;87%
Zeise's dimer

Zeise's dimer

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[Pt2(P(C6H11)Ph2)2(μ-Cl)2Cl2]
20611-44-3, 109131-32-0

[Pt2(P(C6H11)Ph2)2(μ-Cl)2Cl2]

Conditions
ConditionsYield
In further solvent(s) stoich. amts., refluxing and stirring in Cl2CHCHCl2 for 60 min; cooling to room temp., solvent removal (vac.), dissoln. in CHCl3, filtration, hexane addn., crystn. (-30°C); elem. anal.;86%
[PtCl(saccharinate)(1,5-cyclooctadiene)]

[PtCl(saccharinate)(1,5-cyclooctadiene)]

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

trans-[Pt(saccharinate)2(PPh2cyclohexyl)2]

trans-[Pt(saccharinate)2(PPh2cyclohexyl)2]

Conditions
ConditionsYield
In methanol; acetonitrile at 65℃; for 24h;85%
silver thiocyanate
1701-93-5

silver thiocyanate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C55H63AgNP3S

C55H63AgNP3S

Conditions
ConditionsYield
In acetonitrile for 16h; Reflux;84%
potassium cyanide

potassium cyanide

2,2'-thiobis-ethanol
111-48-8

2,2'-thiobis-ethanol

chloroauric acid

chloroauric acid

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

cyano(cyclohexyldiphenylphosphine)gold(I)

cyano(cyclohexyldiphenylphosphine)gold(I)

Conditions
ConditionsYield
In water byproducts: KCl; reduction of HAuCl4 with thiodiglycol at 0°C, followed by the phosphine addition; intermediate complex was washed several times with EtOH and then reacted with KCN; elem. anal.;82%
silver nitrate

silver nitrate

thiosemicarbazide
79-19-6

thiosemicarbazide

acetone
67-64-1

acetone

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[Ag(diphenylcyclohexylphosphine)2(2-(propan-2-ylidene)hydrazinecarbothioamide)]*NO3

[Ag(diphenylcyclohexylphosphine)2(2-(propan-2-ylidene)hydrazinecarbothioamide)]*NO3

Conditions
ConditionsYield
In methanol at 70℃;82%
silver thiocyanate
1701-93-5

silver thiocyanate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

C38H42Ag2N2P2S2

C38H42Ag2N2P2S2

Conditions
ConditionsYield
With pyridine In acetonitrile for 2.5h; Reflux;81%
{WI2(CO)(NCCH3)(C6H5C2)2}2

{WI2(CO)(NCCH3)(C6H5C2)2}2

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

{WI2(CO){P(C6H5)2(C6H11)}2(C6H5C2)2}

{WI2(CO){P(C6H5)2(C6H11)}2(C6H5C2)2}

Conditions
ConditionsYield
In dichloromethane React. of W-compd. with 4 equiv of PPh2Cy (CH2Cl2, dry N2, room temp.).; Elem. anal.;80%
[Pd(3,5-dichloro-2,4,6-trifluorophenyl)2(1,5-cyclooctadiene)]
198142-61-9

[Pd(3,5-dichloro-2,4,6-trifluorophenyl)2(1,5-cyclooctadiene)]

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

cis-[Pd(3,5-dichloro-2,4,6-trifluorophenyl)2(PCyPh2)2]

cis-[Pd(3,5-dichloro-2,4,6-trifluorophenyl)2(PCyPh2)2]

Conditions
ConditionsYield
In tetrahydrofuran to a stirred soln. of complex in THF was added phosphine, 30 min; concd., n-hexane was added, evapd.; elem. anal.;80%
bis(1,5-cyclooctadiene)nickel (0)
1295-35-8

bis(1,5-cyclooctadiene)nickel (0)

N,N-Dimethyl-1-cyanoformamide
16703-51-8

N,N-Dimethyl-1-cyanoformamide

triphenylborane
960-71-4

triphenylborane

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

trans-(Ph2CyP)2Ni(CONMe2)(CN-BPh3)

trans-(Ph2CyP)2Ni(CONMe2)(CN-BPh3)

Conditions
ConditionsYield
In benzene stoich. reaction of nickel compd., phosphine deriv., nitrile deriv. and borane deriv. in benzene at room temp.; evapn., washing with hexane;80%
bis(4-bromomethylphenyl)methanone
31352-40-6

bis(4-bromomethylphenyl)methanone

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

4,4'-bis(((cyclohexyl)diphenylphosphonio)methyl)benzophenone dibromide

4,4'-bis(((cyclohexyl)diphenylphosphonio)methyl)benzophenone dibromide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃; for 72h; Inert atmosphere;80%
saccharin sodium salt
128-44-9

saccharin sodium salt

silver nitrate

silver nitrate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[Ag(μ-saccharinate)(cyclohexyldiphenylphosphine)]2

[Ag(μ-saccharinate)(cyclohexyldiphenylphosphine)]2

Conditions
ConditionsYield
In methanol; water; acetonitrile at 20℃; for 3h; Darkness;80%
palladium diacetate
3375-31-3

palladium diacetate

saccharin
81-07-2

saccharin

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

trans-[Pd(saccharinate)2(H2O)(PPh2Cy)]

trans-[Pd(saccharinate)2(H2O)(PPh2Cy)]

Conditions
ConditionsYield
Stage #1: palladium diacetate; saccharin In water; acetonitrile at 20℃; for 0.5h;
Stage #2: cyclohexyldiphenylphosphine In methanol; water; acetonitrile Reflux;
80%
methanol
67-56-1

methanol

[RhCl(1,5-cyclooctadiene)(tris(hydroxymethyl)phosphine)]
954128-20-2

[RhCl(1,5-cyclooctadiene)(tris(hydroxymethyl)phosphine)]

hydrogen
1333-74-0

hydrogen

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

cis,mer-Rh(H)2Cl(PCyPh2)3

cis,mer-Rh(H)2Cl(PCyPh2)3

Conditions
ConditionsYield
In methanol; [(2)H6]acetone 2 equiv. of PMePh2 in acetone-d4 added to soln. of Rh complex in CH3OH at room temp.(Ar) in NMR tube, filled with H2, shaked; crystd. for 12 h, filtered, washed (Et2O), dried (vac.) overnight;79%
sodium barbital
144-02-5

sodium barbital

silver nitrate

silver nitrate

cyclohexyldiphenylphosphine
6372-42-5

cyclohexyldiphenylphosphine

[Ag(5,5-diethylbarbiturate)(diphenylcyclohexylphosphine)]

[Ag(5,5-diethylbarbiturate)(diphenylcyclohexylphosphine)]

Conditions
ConditionsYield
In water; isopropyl alcohol; acetonitrile at 20℃; for 1h;79%

Cyclohexyldiphenylphosphine Chemical Properties

Molecular Structure of Cyclohexyldiphenylphosphine (CAS NO.6372-42-5):

IUPAC Name: Cyclohexyl(diphenyl)phosphane 
Molecular Formula: C18H21P
Molecular Weight: 268.34
EINECS: 228-904-2 
XLogP3-AA: 4.9
H-Bond Donor: 0
H-Bond Acceptor: 0
Melting Point: 58-62 °C(lit.)
Flash Point: 189.4 °C
Enthalpy of Vaporization: 59.7 kJ/mol
Boiling Point: 374 °C at 760 mmHg
Vapour Pressure: 1.85E-05 mmHg at 25 °C
Water Solubility: insoluble
Sensitive: Air Sensitive
Appearance: white to light yellow crystal powder
Canonical SMILES: C1CCC(CC1)P(C2=CC=CC=C2)C3=CC=CC=C3
InChI: InChI=1S/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2
InChIKey: ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
Product Categories: Ligand; Phosphine Ligands; Synthetic Organic Chemistry; Basic Phosphine LigandsCatalysis and Inorganic Chemistry; Catalysis and Inorganic Chemistry; Cross-Coupling; Phosphine Ligands; Phosphorus Compounds

Cyclohexyldiphenylphosphine Safety Profile

Safety Information of Cyclohexyldiphenylphosphine (CAS NO.6372-42-5):
Safety Statements: 24/25 
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: SY8387500

Cyclohexyldiphenylphosphine Specification

 Cyclohexyldiphenylphosphine (CAS NO.6372-42-5), its Synonyms are Diphenylcyclohexylphosphine ; Phosphine, cyclohexyldiphenyl- ; Cyclohexyldiphenyl-phosphin ; Cyclohexyl diphenyl phosphine .

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