Ethanethiol supplier | CasNO.75-08-1

Name
Ethanethiol
EINECS 200-837-3
CAS No. 75-08-1
Article Data325
CAS DataBase
Density 0.822 g/cm³
Solubility
Melting Point -148 °C
Formula C₂H₆S
Boiling Point 34.663 °C at 760 mmHg
Molecular Weight 62.1356
Flash Point 1 °F
Transport Information UN 2363 3/PG 1
Appearance colourless liquid
Safety 16-25-60-61
Risk Codes 11-20-50/53
Molecular Structure
Hazard Symbols F; Xn;N
Synonyms Ethylhydrosulfide;Ethyl mercaptan;Ethyl thioalcohol;Mercaptoethane;NSC 93877;Thioethanol;Thioethyl alcohol;
PSA 38.80000
LogP 0.93610

Synthetic route

: 98773-05-8, 115958-66-2
trichlorogallium * ethanethiol

: 60-29-7
diethyl ether

A: 2700-40-5
galliumtrichloride * diethylether

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene under inert gas; 5.88 mmol Et2O added to 5.88 mmol of the Ga compound in benzene; stirring at room temp.; 2 phases sepd.; oily phase stirred with n-pentane and dried in vac.; elem. anal.;	A 99% B n/a

...Expand

: 94627-22-2
(n-C3H7)2BSC2H5

A: 28872-72-2
(amino)di-n-propylborane

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With NH3	A 98.5% B n/a

: 129137-38-8
3α-(1,1-Bisethylthioethyl)-3β-hydroxy-14α-methyl-4-nor-5α-cholest-8-ene

A: 129137-44-6
3α-(1-Ethylthioethenyl)-3β-hydroxy-14α-methyl-4-nor-5α-cholest-8-ene

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h;	A 98% B n/a
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h; other substrates;	A 98% B n/a

: 98773-05-8, 115958-66-2
trichlorogallium * ethanethiol

: 3908-55-2
Trimethyl(methylthio)silane

A: 75-77-4
chloro-trimethyl-silane

B: dichloro(ethylthio)gallane

C: dichloro(methylthio)gallane

D: 74-93-1
methylthiol

E: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene 4.62 mmol Me3SiSMe added to 4.62 mmol of the Ga compound in benzene; stirring at room temp.; filtration; solvent removed in vac.; elem. anal. (Cl2GaSC2H5);	A n/a B 98% C n/a D n/a E n/a

...Expand

: 98773-05-8, 115958-66-2
trichlorogallium * ethanethiol

: 35029-96-0
lead bis(methylthiolate)

A: dichloro(ethylthio)gallane

B: dichloro(methylthio)gallane

C: 74-93-1
methylthiol

D: 75-08-1
ethanethiol

E: lead(II) chloride

Conditions

Conditions	Yield
In benzene 2.10 mmol Pb(SCH3)2 added to 4.20 mmol of the Ga compound in benzene; stirring at room temp.; filtration; solvent removed in vac.; residue washed with n-pentane and dried in vac.; elem. anal. (Cl2GaSC2H5);	A 98% B n/a C n/a D n/a E n/a

...Expand

: 83962-17-8
isopentyl-dithiocarbamic acid ethyl ester

A: 628-03-5
isopentyl isothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 97% B n/a

: 129137-47-9
3β-(1,1-Bisethylthioethyl)-3α-hydroxy-14α-methyl-4-nor-5β-cholest-8-ene

A: 129137-50-4
3β-(1-Ethylthioethenyl)-3-α-hydroxy-14α-methyl-4-nor-5β-cholest-8-ene

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h;	A 97% B n/a

: 130474-23-6
(3R,5S,8R,9S,10S,13R,14S,17R)-3-(1,1-Bis-ethylsulfanyl-ethyl)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol

A: 130474-27-0
(3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-3-(1-ethylsulfanyl-vinyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h;	A 97% B n/a

: 74-93-1
methylthiol

: 74-85-1
ethene

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 352-93-2
diethyl sulphide

D: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With 2,2-dimethoxy-2-phenylacetophenone at 45℃; under 2250.23 - 6750.68 Torr; for 14.1h; UV-irradiation;	A n/a B 97% C n/a D n/a

...Expand

: 98773-05-8, 115958-66-2
trichlorogallium * ethanethiol

: 75-18-3
dimethylsulfide

A: 15171-34-3
galliumtrichloride * dimethylsulfide

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene under inert gas; 6.30 mmol Et2S added to 6.30 mmol of the Ga compound in benzene; stirring at room temp.; 2 phases sepd.; oily phase stirred with n-pentane and dried in vac.; elem. anal.;	A 97% B n/a

...Expand

: 115958-68-4, 98772-97-5
aluminiumtrichloride*ethanediol

: 60-29-7
diethyl ether

A: 14640-05-2, 856321-02-3
aluminium trichloride-diethyl ether (1/1)

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene under inert gas; 4.24 mmol Et2O added to 4.23 mmol of the Al compound in benzene; stirring at room temp.; solvent evapd. in vac., residue washed with n-pentane and dried in vac.; elem. anal.;	A 97% B n/a

...Expand

: 110-81-6
Diethyl disulfide

: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With tri-n-butyl-tin hydride In various solvent(s) under 0.0750075 Torr; Reduction;	96%
at 496℃; mit Naphtha-Daempfen;
With diethyl ether; sodium

: 52664-26-3
Methyldithiocarbamidsaeure-ethylester

A: 556-61-6
methyl thioisocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 96% B n/a

: 130474-22-5
(3S,5S,8R,9S,10S,13R,14S,17R)-3-(1,1-Bis-ethylsulfanyl-ethyl)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol

A: 130474-26-9
(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-3-(1-ethylsulfanyl-vinyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h;	A 96% B n/a

: 115958-68-4, 98772-97-5
aluminiumtrichloride*ethanediol

: 75-18-3
dimethylsulfide

A: 15171-30-9, 856320-96-2
aluminiumtrichloride * dimethylsulfide

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene under inert gas; 5.52 mmol Et2S added to 5.53 mmol of the Al compound in benzene; stirring at room temp.; solvent evapd. in vac.; residue washed with n-pentane and dried in vac.; elem. anal.;	A 96% B n/a

...Expand

: 20472-54-2
diethyl dimethylphosphoramidodithioite

A: 688-62-0
triethyl trithiophosphite

B: dimethylammonium dihydrogen phosphite

C: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With water at 120 - 130℃; for 0.5h;	A 81% B 72% C 95%

...Expand

: 31716-60-6
ethyl cyclohexyldithiocarbamate

A: 75-08-1
ethanethiol

B: 1122-82-3
isothiocyanatocyclohexane

Conditions

Conditions	Yield
at 250 - 260℃;	A 95% B 92%

: 115958-68-4, 98772-97-5
aluminiumtrichloride*ethanediol

: 75-50-3
trimethylamine

A: 878784-74-8, 13869-44-8
aluminiumtrichloride * trimethylamine

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In benzene under inert gas; 6.06 mmol Me3N in benzene added to 6.04 mmol of the Al compound in benzene; stirring at room temp.; solvent removed in vac.; residue washed with n-pentane and dried in vac.; elem. anal.;	A 95% B n/a

...Expand

: 130474-24-7
3,3-Bis-ethylsulfanyl-2-phenyl-butan-2-ol

A: 130474-28-1
3-Ethylsulfanyl-2-phenyl-but-3-en-2-ol

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With copper(l) chloride In N,N-dimethyl-formamide at 50℃; for 0.166667h;	A 94% B n/a

: [Zn(HB(C3H2N2SC6H4(OCH3))2(CH3C3HN2(C6H5)))SC2H5]*0.25CH2Cl2

: 74-88-4
methyl iodide

A: [Zn(HB(C3H2N2SC6H4(OCH3))2(CH3C3HN2(C6H5)))I]

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
In chloroform 1:1 mixt. stirred for 10 min; evapd., washed (Et2O), dried (vac.); NMR;	A 94% B n/a

...Expand

: 56134-96-4
ethyl butyldithiocarbamate

A: 592-82-5
butyl isothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 93% B n/a

: 29677-64-3
diethyldithiocarbamic acid

A: 542-85-8
Ethyl isothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 87% B 93%

: 88890-93-1
ethyl ethylselenosulfenate

: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With tri-n-butyl-tin hydride In various solvent(s) under 0.0750075 Torr; Reduction;	92%

: 83962-19-0
Octyl-dithiocarbamic acid ethyl ester

A: 4430-45-9
n-octylisothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 91% B n/a

: 83962-15-6
Propyl-dithiocarbamic acid ethyl ester

A: 628-30-8
n-Propyl isothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 89% B n/a

: 688-62-0
triethyl trithiophosphite

: 65-85-0
benzoic acid

A: 1484-17-9
S-ethyl thiobenzoate

B: 75-08-1
ethanethiol

C 52 percent phosphorous acid: 52 percent phosphorous acid

Conditions

Conditions	Yield
at 120 - 130℃; under 90 Torr; for 4h; Product distribution;	A 89% B 61% C n/a

...Expand

: 4426-32-8
diethyl-thioborinic acid ethyl ester

A: 18483-79-9
Diethylaminoboran

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With NH3 -70°C, then warming at room temp. 15 h;	A 89% B n/a

: 2938-86-5
ethanesulfenyl-dibutyl-borane

A: 1767-37-9
(amino)di-n-butylborane

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With ammonia	A 88.5% B n/a
With NH3	A 88.5% B n/a

: 83962-18-9
Hexyl-dithiocarbamic acid ethyl ester

A: 4404-45-9
n-hexyl isothiocyanate

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
at 250 - 260℃;	A 85% B n/a

: 50-00-0
formaldehyd

: 75-08-1
ethanethiol

: 15909-30-5
(ethylthio)methanol

Conditions

Conditions	Yield
With sodium hydroxide; water at 25 - 40℃; for 1h; Addition;	100%
With water
for 2h; Ambient temperature;

: 75-08-1
ethanethiol

: 110-81-6
Diethyl disulfide

Conditions

Conditions	Yield
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione In chloroform at 20℃;	100%
With air; iron(III) chloride; sodium iodide In acetonitrile for 0.116667h; Ambient temperature;	98%
With oxygen; SiO2-Cl In dichloromethane at 0℃; for 0.166667h;	98%

: 106-96-7
propargyl bromide

: 75-08-1
ethanethiol

: 7310-92-1
propargyl ethyl sulfide

Conditions

Conditions	Yield
With sodium hydroxide In methanol at 0 - 20℃; for 1h;	100%
(i) Na, liq. NH3, (ii) /BRN= 605309/; Multistep reaction;
With sodium ethanolate In ethanol

: 79-43-6
dichloro-acetic acid

: 75-08-1
ethanethiol

: 10490-06-9
glyoxalic acid ethylthioacetal

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 25℃;	100%
With sodium hydride In tetrahydrofuran

: 6972-27-6
1,3-Dimethyl-6-chlorouracil

: 75-08-1
ethanethiol

: 35218-96-3
6-Ethylsulfanyl-1,3-dimethyl-1H-pyrimidine-2,4-dione

Conditions

Conditions	Yield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane; water for 2.5h; Ambient temperature;	100%

: 120-46-7
1,3-diphenylpropanedione

: 75-08-1
ethanethiol

: 70769-74-3
3-ethylsulfanyl-1,3-diphenylprop-2-en-1-one

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In benzene for 15h; Heating;	100%

: 39686-94-7, 56632-47-4, 65827-58-9, 99202-62-7, 99202-66-1, 103082-79-7, 103703-00-0, 103703-01-1, 118711-49-2, 127853-23-0, 139563-66-9
1,2,4,6-tetra-O-acetyl-3-O-benzyl-β-D-glucopyranose

: 75-08-1
ethanethiol

: 146530-62-3
ethyl 2,4,6-tri-O-acetyl-3-O-benzyl-1-thio-β-D-glucopyranoside

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane for 2h; Ambient temperature;	100%
With molecular sieve; boron trifluoride diethyl etherate In dichloromethane for 2h; Ambient temperature;	91%
With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve In dichloromethane at 0℃; for 2h;	79%

: 602-01-7
1-methyl-2,3-dinitrobenzene

: 75-08-1
ethanethiol

: 2-Ethylsulfanyl-1-methyl-3-nitro-benzene

Conditions

Conditions	Yield
With lithium hydroxide In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃;	100%

: 87840-68-4
diethyl 2,4-dinitrobenzylidenemalonate

: 75-08-1
ethanethiol

: 1-(2,4-dinitrophenyl)-1-ethylthio-2,2-diethoxycarbonylethane

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran Ambient temperature;	100%

: 78102-17-7
cis-2,6-dihydroxy-1,4-dioxathiane

: 75-08-1
ethanethiol

: 84373-82-0
thiodiglycolaldehyde bis(diethyl dithioacetal)

Conditions

Conditions	Yield
With hydrogenchloride at 0℃; for 0.5h;	100%

: 71461-30-8
(S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester

: 75-08-1
ethanethiol

: 105089-87-0
benzyl (2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolecarboxylate

Conditions

Conditions	Yield
Stage #1: (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester; ethanethiol In chloroform for 0.5h; Inert atmosphere; Stage #2: With chloro-trimethyl-silane In chloroform at 20℃; Inert atmosphere;	100%
With chloro-trimethyl-silane In chloroform	79%

: 127232-51-3, 127306-30-3
(3S,4R)-3-Hydroxy-1,4-dimethyl-5-oxo-3-((3aR,5S,7R,7aR)-2,2,7-trimethyl-tetrahydro-[1,3]dioxolo[4,5-b]pyran-5-yl)-pyrrolidine-2,2-dicarboxylic acid dimethyl ester

: 75-08-1
ethanethiol

: 127255-09-8
(3R,3aS,4S,6aR)-4-((2R,3R)-4,4-Bis-ethylsulfanyl-3-hydroxy-2-methyl-butyl)-3a-hydroxy-1,3-dimethyl-2,6-dioxo-tetrahydro-furo[3,4-b]pyrrole-6a-carboxylic acid methyl ester

Conditions

Conditions	Yield
With hydrogenchloride	100%

: (5R,6S)-7-Oxo-6-((R)-1-tributylsilanyloxy-ethyl)-3-trifluoromethanesulfonyloxy-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester

: 75-08-1
ethanethiol

: (5R,6S)-3-Ethylsulfanyl-7-oxo-6-((R)-1-tributylsilanyloxy-ethyl)-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile -78 deg C to RT;	100%

: 153750-36-8
(1,2-Epoxydecyl)pentylether

: 75-08-1
ethanethiol

: 1-Ethylsulfanyl-1-pentyloxy-decan-2-ol

Conditions

Conditions	Yield
In toluene for 20h; Ambient temperature;	100%

: 96286-28-1
5-Methoxy-4-phenyl-5,6-dihydro-4H-[1,3,4]thiadiazine

: 75-08-1
ethanethiol

: 5-Ethylsulfanyl-4-phenyl-5,6-dihydro-4H-[1,3,4]thiadiazine

Conditions

Conditions	Yield
Ambient temperature;	100%

: 146446-29-9
1,1-dibromo-4-chloro-3,3-dimethyl-2-butanone

: 75-08-1
ethanethiol

: 146679-12-1
4-chloro-1-(ethylthio)-3,3-dimethyl-2-butanone

Conditions

Conditions	Yield
With sodium methylate In methanol for 1h; Ambient temperature;	100%
With sodium methylate 1.) MeOH, ice-cooling, 5 min, 2.) r.t., 1 h; Yield given;

: 109687-65-2
(S)-(-)-1,1-dimethylethyl <3-methyl-1-<<(methylsulfonyl)oxy>methyl>butyl>carbamate

: 75-08-1
ethanethiol

: 167421-94-5
tert-butyl (S)-N-[1-(ethylsulfanylmethyl)-3-methylbutyl]carbamate

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran Heating;	100%

: 126301-19-7, 134807-64-0, 109687-66-3
(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

: 75-08-1
ethanethiol

: 167421-92-3
tert-butyl (S)-N-[1-(ethylsulfanylmethyl)-2-phenylethyl]carbamate

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 67℃; for 2h;	100%
Stage #1: ethanethiol With sodium hydride In tetrahydrofuran at 20℃; for 1h; Stage #2: (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate In tetrahydrofuran at 20℃; for 12h;

: 132482-10-1
(R)-1-<(1,1-dimethylethoxy)carbonyl>-2-pyrrolidinemethanolmethanesulfonate

: 75-08-1
ethanethiol

: (R)-2-Ethylsulfanylmethyl-pyrrolidine-1-carboxylic acid tert-butyl ester

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran Heating;	100%

: 153923-41-2
(S)-2-[ (tert-butoxycarbonyl)-amino]-3-(4-methoxyphenyl)-propylmethanesulfonate

: 75-08-1
ethanethiol

: 167421-95-6
[(S)-1-Ethylsulfanylmethyl-2-(4-methoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran for 2h; Heating;	100%

: 167421-90-1
4-((S)-2-tert-Butoxycarbonylamino-3-methanesulfonyloxy-propyl)-imidazole-1-carboxylic acid tert-butyl ester

: 75-08-1
ethanethiol

: 167421-96-7
[(S)-1-Ethylsulfanylmethyl-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid tert-butyl ester

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran Heating;	100%

: isobutyl 2,3,4-trichlorobenzamide

: 75-08-1
ethanethiol

: 3,4-Dichloro-2-ethylsulfanyl-N-isobutyl-benzamide

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃;	100%

: 106-93-4
ethylene dibromide

: 75-08-1
ethanethiol

: 5244-34-8
2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 1h; Heating;	100%

: 188976-06-9
N-propargyl-2,4-bis(trifluoroacetyl)-1-naphthylamine

: 75-08-1
ethanethiol

: 1-(3-Ethylsulfanylmethyl-4-trifluoromethyl-benzo[h]quinolin-6-yl)-2,2,2-trifluoro-ethanone

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 24h; Ambient temperature;	100%

: 161755-20-0
(-)-(4S,5R,2'S,3'R)-3-(3-hydroxy-2-methylbutanoyl)-4-methyl-5-phenyl-1,3-oxazolidin-2-one

: 75-08-1
ethanethiol

A: 16251-45-9, 17097-67-5, 28044-22-6, 28044-23-7, 39663-75-7, 54418-69-8, 77943-39-6, 125133-96-2, 149055-02-7
(4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one

B: 213319-90-5
(+)-S-ethyl (2S,3R)-3-hydroxy-2-methylbutanethioate

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Substitution;	A 100% B 99%

...Expand

: 75-08-1
ethanethiol

: p-toluenesulfonylacetylene

: (Z)-2-(ethylthio)-1-p-toluenesulfonylethylene

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 48h; Addition; Michael addition;	100%

: 75-08-1
ethanethiol

: 245736-59-8
2-{6-[7-(4-benzyl-2-oxo-oxazolidine-3-carbonyl)-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-5,9-dimethyl-6-oxo-undec-10-ynyl]-2-methoxy-4-methoxycarbonylmethylene-tetrahydro-pyran-2-yl}-propionic acid benzyl ester

: (S)-2-{(2S,6R)-6-[(1R,4R,5R,7S,9R)-4-(tert-Butyl-dimethyl-silanyloxy)-7-ethylsulfanylcarbonyl-1-(4-methoxy-benzyloxy)-5,9-dimethyl-6-oxo-undec-10-ynyl]-2-methoxy-4-[1-methoxycarbonyl-meth-(E)-ylidene]-tetrahydro-pyran-2-yl}-propionic acid benzyl ester

Conditions

Conditions	Yield
With potassium hydride In tetrahydrofuran at 25℃; for 3h;	100%

: 75-08-1
ethanethiol

: (2S,3S,4R,5R)-2-Acetoxy-3,4,5-tris-benzyloxy-piperidine-1-carboxylic acid benzyl ester

: ethyl 2,3,4-tri-O-benzyl-5-benzyloxycarbonylamino-5-deoxy-1-thio-D-arabinopyranoside

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve In dichloromethane at 0℃; for 1.08333h; Substitution;	100%

: 89-98-5
2-chloro-benzaldehyde

: 75-08-1
ethanethiol

: 53606-33-0
2-(ethylsulfanyl)benzenecarbaldehyde

Conditions

Conditions	Yield
Stage #1: ethanethiol With sodium hydroxide In water at 20℃; for 0.5h; Stage #2: 2-chloro-benzaldehyde With tetrabutylammomium bromide In water at 82℃;	100%
With tetrabutylammomium bromide; sodium hydroxide In water at 82℃; for 4 - 6h;	95%
With sodium carbonate In N,N-dimethyl-formamide at 100℃; for 24h;	80%
Stage #1: ethanethiol With sodium hydroxide In water for 1h; Stage #2: 2-chloro-benzaldehyde With tetrabutylammomium bromide In water for 4h; Reflux;

: 75-26-3
isopropyl bromide

: 75-08-1
ethanethiol

: 5145-99-3
ethyl isopropyl sulfide

Conditions

Conditions	Yield
Stage #1: ethanethiol With sodium tetrahydroborate; sodium hydroxide In water at 5℃; Inert atmosphere; Stage #2: isopropyl bromide; tetrabutylammomium bromide In water at 50℃; Inert atmosphere;	100%
With potassium hydroxide In ethanol for 0.5h; Heating;	51%

Ethanethiol Consensus Reports

ETHYL MERCAPTAN is reported in EPA TSCA Inventory.

Ethanethiol Standards and Recommendations

OSHA PEL: TWA 0.5 ppm
ACGIH TLV: TWA 0.5 ppm
DFG MAK: 0.5 ppm (1.3 mg/m³)
NIOSH REL: (n-Alkane Mono Thiols) CL 0.5 ppm/15M
DOT Classification: 3; Label: Flammable Liquid; DOT Class: 6.1; Label: Poison, Flammable Liquid

Ethanethiol Specification

The Ethanethiol, with the CAS registry number 75-08-1 and EINECS registry number 200-837-3, has the systemtic name and IUPAC name of ethanethiol. It is a kind of colourless liquid with a strongly disagreeable odor which resembles that of leeks or onions. And the molecular formula of this chemical is C₂H₆S.What's more ,Its systematic name is Ethanethiol.The presence of S in the structure leads to many different properties, most notably the infamous odour of EtSH. And it is also more volatile than ethanol because of a diminished ability to engage in hydrogen bonding. Therefore, it it can be added to otherwise odourless gas products such as liquefied petroleum gas (LPG) to help warn of gas leaks, of course, it is not harmful at these concentrations.

The physical properties of Ethanethiol are as followings:
(1)ACD/LogP: 1.44; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.442; (4)ACD/LogD (pH 7.4): 1.441; (5)ACD/BCF (pH 5.5): 7.339; (6)ACD/BCF (pH 7.4): 7.333; (7)ACD/KOC (pH 5.5): 144.953; (8)ACD/KOC (pH 7.4): 144.847; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 38.8 Å²; (13)Index of Refraction: 1.422; (14)Molar Refractivity: 19.211 cm³; (15)Molar Volume: 75.597 cm³; (16)Polarizability: 7.616×10^-24cm³; (17)Surface Tension: 21.924 dyne/cm; (18)Density: 0.822 g/cm³; (19)Enthalpy of Vaporization: 26.79 kJ/mol; (20)Boiling Point: 34.663 °C at 760 mmHg; (21)Vapour Pressure: 537.074 mmHg at 25°C.

Preparation of Ethanethiol:
It can be prepared by absolute ethyl alcohol, fuming sulfuric acid and sodium hydrosulfide.
C₂H₅OH+H₂SO₄^.SO₃→C₂H₅OSO₂OH+H₂SO₄2C₂H₅OSO₂OH+Na₂CO₃→2C₂H₅OSO₂ONa+H₂O+CO₂↑
C₂H₅OSO₂ONa+NaSH→C₂H₅SH+Na₂SO₄

Uses of Ethanethiol:
It is often used as pesticide intermediates and air alert. And it is also used as stabilizer in the adhesives and intermediates in organic synthesis.

Safety information of Ethanethiol:
You should be cautious while dealing with this chemical. It is a kind of flammble chemcial which is very toxic to aquatic organisms, and may cause long-term adverse effects in the aquatic environment. It is also harmful by inhalation. Therefore, you had better take the following instructions: Keep away from sources of ignition - No smoking; Avoid contact with eyes; This material and/or its container must be disposed of as hazardous waste; Avoid release to the environment. Refer to special instructions safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: CCS
(2)InChI: InChI=1/C2H6S/c1-2-3/h3H,2H2,1H3
(3)InChIKey: DNJIEGIFACGWOD-UHFFFAOYAW

The toxicity data of Ethanethiol is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	2770ppm/4H (2770ppm)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat	LC50	inhalation	4420ppm/4H (4420ppm)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: CYANOSIS	American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat	LD50	intraperitoneal	226mg/kg (226mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat	LD50	oral	682mg/kg (682mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.

Product Name

Ethanethiol

Synthetic route

Ethanethiol Consensus Reports

Ethanethiol Standards and Recommendations

Ethanethiol Specification

Related Products

Hot Products