Guanosine supplier | CasNO.118-00-3

Name
Guanosine
EINECS 204-227-8
CAS No. 118-00-3
Article Data143
CAS DataBase
Density 2.258 g/cm³
Solubility 0.75 g/L (25 °C) in water
Melting Point 250 °C (dec.)(lit.)
Formula C₁₀H₁₃N₅O₅
Boiling Point 775.9°C at 760 mmHg
Molecular Weight 283.244
Flash Point 423.1oC
Transport Information UN 2811 6.1/PG 3
Appearance crystalline
Safety 45-24/25-23
Risk Codes 25
Molecular Structure
Hazard Symbols T,Xi
Synonyms Inosine, 2-amino-;2-amino-9-pentofuranosyl-9H-purin-6-ol;Ribofuranoside, guanine-9, .beta.-D-;Guanine, 9-.beta.-D-ribofuranosyl-;D-Guanosine;Guanosine(GR);2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one;Guo;Guanine-9-beta-D-ribofuranoside;2H-Purin-2-one,6-amino-1,3-dihydro-;beta-D-Ribofuranoside, guanine-9;2(3H)-Imino-9-.beta.-D-ribofuranosyl-9H-purin-6(1H)-one;9-beta-D-Ribofuranosylguanine;9H-purin-6-ol, 2-amino-9-pentofuranosyl-;9-(beta-D-Ribofuranosyl)guanine;2-Amino-9-.beta.-D-ribofuranosyl-9-H-purine-6(1H)-one;
PSA 159.51000
LogP -2.10550

Synthetic route

: 2-N-(N,N-dibenzylformamidino)-9-(2,3-O-benzylidene-β-D-ribofuranosyl)-guanine

: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal; palladium hydroxide - carbon In water; tert-butyl alcohol at 20℃; under 2068.59 Torr; for 20h; Hydrogenolysis;	99%

: 2',3'-O-benzylidene-2N-dimethylaminomethylene guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal; palladium hydroxide - carbon In water; tert-butyl alcohol at 20℃; under 2068.59 Torr; for 20h; Hydrogenolysis;	98%

: 100313-43-7
N-2-(ethoxycarbonyl)guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With pyridine; ammonium hydroxide at 45℃; for 48h;	95%

: 9-(2',3'-di-O-acetyl-β-D-ribofuranosyl)-N2-isobutanoylguanine

: 118-00-3
G

Conditions

Conditions	Yield
With ammonia In methanol at 25 - 28℃; for 10h;	90%

: 6979-94-8
2',3',5'-tri-O-acetyl-guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With methanol; water; triethylamine at 71℃; Microwave irradiation;	89%

: 41623-91-0
2-bromo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)hypoxanthine

: 118-00-3
G

Conditions

Conditions	Yield
With ammonia In methanol at 120℃;	80%
With ammonium hydroxide at 150℃; for 3h;	48%

: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(6-diphenylcarbamoyloxy-2-isobutyrylamino-purin-9-yl)-tetrahydro-furan-3-yl ester

: 118-00-3
G

Conditions

Conditions	Yield
With methanol; ammonia for 24h; Ambient temperature;	80%

: 112233-75-7
2-(acetylamino)-6-(diphenylcarbamoyloxy)-9-(β-D-tri-O-acetylribofuranosyl)-9H-purine

: 118-00-3
G

Conditions

Conditions	Yield
With ammonia In methanol; water at 60℃;	75%
With methanol; ammonia for 24h; Ambient temperature;	75%

: 58917-66-1
2',1''-anhydro-5-<(1''-benzamido-1''-hydroxymethylene)amino>-1-(β-D-ribofuranosyl)imidazole-4-carboxamide

A: 118-00-3
G

B: [1-(15)N]guanosine

C: 103654-70-2
<15NH2>guanosine

Conditions

Conditions	Yield
With (15N)-ammonium chloride In dimethyl sulfoxide at 100℃; for 240h; Yields of byproduct given;	A n/a B 75% C n/a
With (15N)-ammonium chloride In dimethyl sulfoxide at 100℃; for 240h; Yield given. Yields of byproduct given;

...Expand

: 26001-38-7
8-mercaptoguanosine

: 118-00-3
G

Conditions

Conditions	Yield
With potassium bromide In water at 20℃; pH=7; Reagent/catalyst; Inert atmosphere; Irradiation;	57.4%
Multi-step reaction with 3 steps 1: dihydrogen peroxide; acetic acid / 48 h / 65 °C 2: lithium hydroxide; water-d2 / Sonication 3: 24 h / 50 °C View Scheme

: 133068-54-9
1-(β-D-ribofuranosyl)-5-(thiocarbamoyl)amino-1H-imidazole-4-carboxamide

: 118-00-3
G

Conditions

Conditions	Yield
With sodium hydroxide; copper diacetate for 1.5h; Heating;	53%

: 146-77-0
2-Chloroadenosine

: 118-00-3
G

Conditions

Conditions	Yield
With acetic acid; sodium nitrite anschl. Erhitzen mit aethanol. NH3;

: 18646-11-2
α-D-ribofuranosyl-1-phosphate

: 73-40-5
guanine

: 118-00-3
G

Conditions

Conditions	Yield
bei der Einwirkung von Purinnucleosid-Phosphorylase;

: 30747-23-0
Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester

: 118-00-3
G

Conditions

Conditions	Yield
With ammonia In methanol for 42h; Ambient temperature;
Multi-step reaction with 2 steps 1: 77 percent / EtN(i-Pr)2 / pyridine / 1 h / Ambient temperature 2: 75 percent / NH3/MeOH / 24 h / Ambient temperature View Scheme

: 17494-84-7
N2-acetyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)guanine

: 118-00-3
G

Conditions

Conditions	Yield
With ammonia In methanol for 42h; Ambient temperature;

: 4552-61-8
2-amino-6-benzyloxy-9-β-D-ribofuranosylpurine

A: 72360-76-0
7-benzylguanosine

B: 88158-12-7
8-benzylguanosine

C: 71171-58-9
N2-benzyl-2'-deoxyguanosine

D: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen cation In methanol; water at 40℃; Rate constant; Mechanism; pH 3.5, MeOH/aqueous buffer (5:95); other pH;	A 0.4 % Chromat. B 0.5 % Chromat. C 1.2 % Chromat. D 97.9 % Chromat.

...Expand

: 79384-30-8
O6-(p-methylbenzyl)guanosine

A: 88158-18-3
1-(p-methylbenzyl)guanosine

B: 79396-24-0
N2-(p-methylbenzyl)guanosine

C: 88158-13-8
8-(p-methylbenzyl)guanosine

D: 104375-85-1
C18H21N5O5

E: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen cation In methanol; water at 40℃; Rate constant; Mechanism; pH 3.5, MeOH/aqueous buffer (5:95); other pH;	A 1.2 % Chromat. B 3.9 % Chromat. C 2.6 % Chromat. D 2.9 % Chromat. E 89.4 % Chromat.

...Expand

: 88158-11-6
O6-(p-chlorobenzyl)guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen cation In methanol; water at 40℃; for 336h; Rate constant; Mechanism; pH 3.5, MeOH/aqueous buffer (5:95); other pH;	100 % Chromat.

: 78907-22-9
O6-(p-methoxybenzyl)guanosine

A: 78907-25-2
N2-(p-methoxybenzyl)guanosine

B: 78907-27-4
1-(p-methoxybenzyl)guanosine

C: 78907-24-1
8-(p-methoxybenzyl)guanosine

D: 78907-23-0
7-(p-methoxybenzyl)guanosine

E: 118-00-3
G

Conditions

Conditions	Yield
With hydrogen cation In methanol; water at 40℃; Rate constant; Mechanism; pH 3.5, MeOH/aqueous buffer (5:95); other pH;	A 21.5 % Chromat. B 0.2 % Chromat. C 0.4 % Chromat. D 1.1 % Chromat. E 76.8 % Chromat.

...Expand

: 78907-22-9
O6-(p-methoxybenzyl)guanosine

A: 78907-25-2
N2-(p-methoxybenzyl)guanosine

B: 78907-27-4
1-(p-methoxybenzyl)guanosine

C: 78907-24-1
8-(p-methoxybenzyl)guanosine

D: 78907-23-0
7-(p-methoxybenzyl)guanosine

E: 78907-26-3
4-(p-methoxybenzyl)-5-guanidino-1-β-D-ribofuranozylimidazole

F: 118-00-3
G

Conditions

Conditions	Yield
In methanol; water at 40℃; Rate constant; approximate rate constants for formation of products;

...Expand

: 172793-53-2
CpG

A: 84-52-6
cytidine 3'-monophosphate

B: 118-00-3
G

Conditions

Conditions	Yield
With ribonuclease A Product distribution; determination of structure;

: 69471-61-0
2'-O-(4-methoxytetrahydropyran-4-yl)guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With hydrogenchloride at 22℃; for 0.583333h; Kinetics;	50 % Chromat.

: 78880-62-3
3-(β-D-pentofuranosyl)pyrimido<1,2-a>purin-10(3H)-one

A: 542-78-9
Malondialdehyde

B: 118-00-3
G

Conditions

Conditions	Yield
With sodium hydroxide; water at 45℃;

: 92220-57-0
8-amino-3,10-dihydro-10-oxo-3-β-D-ribofuranosyl-1,3,5-triazino<1,2-a>purine

: 118-00-3
G

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 0.0833333h; Product distribution;

: 87424-18-8
N2-<<9-fluorenylmethyl)oxy>carbonyl>guanosine

: 118-00-3
G

Conditions

Conditions	Yield
With ammonium hydroxide In pyridine at 20℃; for 0.5h;

: cytidine guanosine base pair

A: 118-00-3
G

B: 65-46-3
CYTIDINE

Conditions

Conditions	Yield
In methanol; dimethyl sulfoxide at -26.1 - 29.9℃; Equilibrium constant;

: CpCpGp

A: 84-52-6
cytidine 3'-monophosphate

B: 118-00-3
G

Conditions

Conditions	Yield
With ribonuclease A Product distribution; determination of structure;

: 85-32-5
5'-guanosine monophosphate

: 118-00-3
G

Conditions

Conditions	Yield
With water at 30℃; for 0.166667h; Rate constant; relative rate, different alkaline phosphotases;
In water at 37℃; for 240h;

: 634-02-6
guanosine 2',3'-cyclic monophosphate

A: 117-68-0
guanosine 3'-monophosphate

B: 130-50-7
guanosine 2'-monophosphate

C: 118-00-3
G

Conditions

Conditions	Yield
With chicken plasma membrane protein In water at 30℃; for 2h; Product distribution; other temperatures;

...Expand

: 99519-21-8
C47H60N18O33P4

A: 118-00-3
G

B: 58-96-8
uridine

C: 65-46-3
CYTIDINE

D: 58-61-7
adenosine

Conditions

Conditions	Yield
With Croatalus Adamanteus snake venom phosphodiesterase; MgCl2,tris-hydrochloride buffer; monoesterase In water at 37℃; for 18h; Product distribution;

...Expand

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 118-00-3
G

: 17331-16-7
N2-(dimethylaminomethylene)guanosine

Conditions

Conditions	Yield
In methanol Ambient temperature;	100%
In methanol at 20℃; for 72h;	99%
In methanol for 72h;	99%

: 118-00-3
G

: 4016-63-1
8-bromoguanosine

Conditions

Conditions	Yield
With bromine In water at 20℃;	100%
With bromine In water at 20℃; for 24h;	99%
With bromine In water	93%

: 118-00-3
G

: 406945-71-9
C12H13N7

: 1-(2-amino-9H-purin-6-yl)-4-dimethylamino-pyridinium; 2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olate

Conditions

Conditions	Yield
In water-d2	100%

: 106-95-6
allyl bromide

: 118-00-3
G

: 21869-84-1
7-allyl-2-amino-1H-purine-6(7H)-one

Conditions

Conditions	Yield
Stage #1: allyl bromide; G In dimethyl sulfoxide at 20℃; for 18h; Stage #2: With hydrogenchloride; water In dimethyl sulfoxide for 0.75h; Stage #3: With sodium hydroxide In methanol; water; dimethyl sulfoxide	100%
Stage #1: allyl bromide; G In dimethyl sulfoxide at 20℃; for 18h; Inert atmosphere; Stage #2: With hydrogenchloride In water; dimethyl sulfoxide for 1h;	92.5%
In dimethyl sulfoxide at 20℃; for 24h; Concentration; Inert atmosphere; Large scale;	58.7%

: 118-00-3
G

: 77-76-9
2,2-dimethoxy-propane

: 67-64-1
acetone

: 362-76-5
2',3'-isopropylideneguanosine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 20℃; for 72h; Inert atmosphere;	100%

...Expand

: 108-24-7
acetic anhydride

: 118-00-3
G

: 6979-94-8
2',3',5'-tri-O-acetyl-guanosine

Conditions

Conditions	Yield
With dmap; triethylamine In acetonitrile at 0 - 20℃; for 4h;	99%
With dmap; triethylamine In acetonitrile for 0.5h; Ambient temperature;	98%
With dmap; triethylamine In acetonitrile Heating;	98%

: 118-00-3
G

: 96412-41-8
<8-2H>guanosine

Conditions

Conditions	Yield
With hydrogen; water-d2; palladium on activated charcoal at 110℃; for 24h;	99%
With water-d2 for 15h; Heating;	92%
With water-d2; palladium on activated charcoal; hydrogen at 110℃; for 24h;	92%

: chloro(2,2':6',2''-terpyridine)platinum(II) chloride dihydrate

: 118-00-3
G

: N(1),N(6)-bis[(2,2':6',2''-terpyridine)platinio(II)]guanosine

Conditions

Conditions	Yield
With silver nitrate In water byproducts: AgCl; Pt-complex and Ag-salt soln. heating at 70-80°C for 2 h, AgCl centrifugation off, org. compd. soln. addn., soln. heating at 70°C for 2 h, centrifugation; soln. freeze drying;	99%

: 97-72-3
2-Methylpropionic anhydride

: 118-00-3
G

: 70337-80-3
N2-(2-methylpropanoyl)-2',3',5'-tris-O-(2-methylpropanoyl)guanosine

Conditions

Conditions	Yield
In pyridine at 110℃; for 20h;	98%
With dmap In pyridine at 50℃; for 24h;

: 582-60-5
5,6-dimethyl-1H-benzo[d]imida-zole

: 118-00-3
G

: 13082-84-3
(β-D-ribofuranosyl)-5,6-dimethylbenzimidazole

Conditions

Conditions	Yield
for 1.5h; purine nucleoside phosphorylase of whole cells of E. coli BMT 1D/1A;	98%

: 701-99-5
Phenoxyacetyl chloride

: 118-00-3
G

: 119824-66-7
N2-(phenoxyacetyl)guanosine

Conditions

Conditions	Yield
Stage #1: G With pyridine; chloro-trimethyl-silane In dichloromethane for 2h; Stage #2: Phenoxyacetyl chloride In dichloromethane at 0℃; for 3h; Stage #3: With methanol In dichloromethane at 20℃; for 12h;	98%
With pyridine; chloro-trimethyl-silane; benzotriazol-1-ol 1.) 45 min, 2.) acetonitrile, 55 deg C, 5 h; Yield given. Multistep reaction;
Stage #1: G With pyridine; chloro-trimethyl-silane In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere; Stage #2: Phenoxyacetyl chloride In dichloromethane for 3h; Cooling with ice;	150.2 g

: 118-00-3
G

: 73-40-5
2-amino-1,9-dihydro-6H-purin-6-one

Conditions

Conditions	Yield
With sulfuric acid In water at 90℃; for 1.5h; Reagent/catalyst; Temperature; Solvent; Large scale;	98%
With sodium dichromate In water at 24.85℃; Quantum yield; Further Variations:; Reagents; pH-values; Decomposition; Photolysis;
With Lupinus luteus guanosine-inosine nucleosidase Enzyme kinetics;

: 118-00-3
G

: 67-64-1
acetone

: 362-76-5
2',3'-isopropylideneguanosine

Conditions

Conditions	Yield
With perchloric acid at 20℃; for 1.16667h;	98%
With perchloric acid In water at 20℃; for 4h;	94%
Stage #1: G; acetone With perchloric acid at 20℃; for 1.16667h; Stage #2: With ammonia In water at 0℃;	92%

: 75-36-5
acetyl chloride

: 118-00-3
G

: 129681-72-7, 21967-06-6
N2-acetylguanosine

Conditions

Conditions	Yield
Stage #1: G With pyridine; chloro-trimethyl-silane In dichloromethane for 2h; Stage #2: acetyl chloride In dichloromethane at 0℃; for 1.5h; Stage #3: With methanol In dichloromethane at 20℃; for 12h;	98%

: (diethylenetriamino)copper(II) nitrate

: 54-86-4
sodium nicotinate

: 7732-18-5
water

: 118-00-3
G

: [Cu(diethylenetriamine)(nicotinic acid-H)(N7-guanosine)(NO3)]*5H2O

Conditions

Conditions	Yield
In methanol; ethanol; water soln. of sodium nicotinate (5 mmol) in H2O/EtOH (1/10 v/v) added dropwise to soln. of Cu complex (5 mmol) in H2O/MeOH (1/10 v/v); stirred (5 min); guanosine (5 mmol) in EtOH added; stirred (12 h); solid isolated by filtration; washed with Et2O; dried (room temp.); elem. anal.;	98%

...Expand

: 75-03-6
ethyl iodide

: 118-00-3
G

: 7-ethylguanine hydrochloride

Conditions

Conditions	Yield
Stage #1: ethyl iodide; G In N,N-dimethyl acetamide at 20℃; for 24h; Stage #2: With hydrogenchloride for 1.5h; Heating;	97%

: 123-62-6
propionic acid anhydride

: 118-00-3
G

: 90742-12-4
2',3',5'-tri-O-propionyl-N2-propionylguanosine

Conditions

Conditions	Yield
With dmap In pyridine at 70℃; for 3h;	96%

: 118-00-3
G

: 77-78-1
dimethyl sulfate

: 7-methylguanine hydrochloride

Conditions

Conditions	Yield
Stage #1: G; dimethyl sulfate In N,N-dimethyl acetamide at 20℃; for 6h; Stage #2: With hydrogenchloride for 1.5h; Heating;	96%

: 108-24-7
acetic anhydride

: 118-00-3
G

A: 3056-33-5
2,9-diacetylguanine

B: 13035-61-5
1,2,3,5-tetraacetylribose

Conditions

Conditions	Yield
Stage #1: acetic anhydride; G at 136℃; for 1h; Stage #2: With trifluoroacetic acid at 60 - 100℃;	A 96% B 86%

...Expand

: 108-24-7
acetic anhydride

: 118-00-3
G

: 6979-94-8
2-amino-6-hydroxyl-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

Conditions

Conditions	Yield
With dmap; triethylamine In acetonitrile at 20℃; for 0.5h;	96%
With dmap; triethylamine In acetonitrile at 20℃; for 0.666667h;	96%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 118-00-3
G

: 72409-21-3
5'-O-tert-butyldimethylsilylguanosine

Conditions

Conditions	Yield
With silver nitrate In tetrahydrofuran for 3h; Ambient temperature;	95%
silver nitrate In tetrahydrofuran for 1h;	95%
With dmap; triethylamine In dichloromethane; dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere;	87%

: 69304-37-6
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

: 118-00-3
G

: 69304-44-5
3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide for 0.75h; Ambient temperature;	95%
With 1H-imidazole In pyridine; N,N-dimethyl-formamide for 4h;	93%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; Large scale;	92%

: 85272-31-7
di-tert-butylsilyl bis(trifluoromethanesulfonate)

: 118-00-3
G

: 126628-29-3
2-amino-9-((4aR,6R,7R,7aS)-2,2-di-tert-butyl-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl)-1,9-dihydro-6H-purin-6-one

Conditions

Conditions	Yield
In N,N-dimethyl-formamide	95%
With 2,6-dimethylpyridine In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere;	95%
In N,N-dimethyl-formamide at 0℃; Inert atmosphere;	89%

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 118-00-3
G

: 1055407-32-3
N2-[(dimethylamino)methylene]guanosine

Conditions

Conditions	Yield
In methanol at 27℃; for 96h;	95%

: 75-21-8
oxirane

: 118-00-3
G

: 7-(2'-hydroxyethyl)guanine hydrochloride

Conditions

Conditions	Yield
Stage #1: oxirane; G With acetic acid at 100℃; for 0.5h; Stage #2: With hydrogenchloride for 1.5h; Heating;	95%

: 3375-31-3
palladium diacetate

: 118-00-3
G

: Pd(2+)*CH3COO(1-)*C10H12N5O5(1-)*3H2O=[Pd(CH3COO)(C10H12N5O5)]*3H2O

Conditions

Conditions	Yield
In water; acetone stirring (hot soln., 3 h), pptn.; centrifugation, washing (water, acetone), drying (air); elem. anal.;	95%

: 75-03-6
ethyl iodide

: 118-00-3
G

: 7-ethylguanine

Conditions

Conditions	Yield
Stage #1: ethyl iodide; G In N,N-dimethyl acetamide at 60℃; Inert atmosphere; Stage #2: With hydrogenchloride In N,N-dimethyl acetamide; water at 110℃; for 1h; Stage #3: With ammonia In N,N-dimethyl acetamide; water at 20℃;	95%
Stage #1: ethyl iodide; G In N,N-dimethyl acetamide at 60℃; Inert atmosphere; Stage #2: With hydrogenchloride In N,N-dimethyl acetamide; water at 110℃; for 1h;	95%

Guanosine Consensus Reports

Reported in EPA TSCA Inventory.

Guanosine Specification

The Guanosine, with the CAS registry number 118-00-3 and EINECS registry number 204-227-8, has the IUPAC name of 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one. It belongs to the following product categories: Pharmaceutical Intermediates; Purine; API intermediates; Biochemistry; Nucleosides and their analogs; Nucleosides, Nucleotides & Related Reagents; Bases & Related Reagents. And the molecular formula of the chemical is C₁₀H₁₃N₅O₅.

The Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a -N9-glycosidic bond, and is required for an RNA splicing reaction in mRNA. What's more, it is always used in herpes treatment.

The physical properties of Guanosine are as followings: (1)# of Rule of 5 Violations: 2; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1.284; (5)ACD/KOC (pH 7.4): 1.278; (6)#H bond acceptors: 10; (7)#H bond donors: 6; (8)#Freely Rotating Bonds: 5; (9)Polar Surface Area: 155.22 Å²; (10)Index of Refraction: 1.955; (11)Molar Refractivity: 60.811 cm³; (12)Molar Volume: 125.448 cm³; (13)Polarizability: 24.107×10^-24cm³; (14)Surface Tension: 123.824 dyne/cm; (15)Density: 2.258 g/cm³.

You should be cautious while dealing with this chemical. It is toxic if swallowed. Therefore, you had better take the following instructions: Avoid contact with skin and eyes; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible); Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).

You can still convert the following datas into molecular structure:
(1)SMILES: c1nc2c(=O)[nH]c(nc2n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N
(2)InChI: InChI=1/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
(3)InChIKey: NYHBQMYGNKIUIF-UUOKFMHZBU

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	500mg/kg (500mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	intravenous	180mg/kg (180mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03206,

Product Name

Guanosine

Synthetic route

Guanosine Consensus Reports

Guanosine Specification

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