J acid supplier | CasNO.87-02-5

Name
J acid
EINECS 201-718-9
CAS No. 87-02-5
Article Data9
CAS DataBase
Density 1.627 g/cm³
Solubility Soluble in hot water, soda ash and caustic soda
Melting Point
Formula C₁₀H₉NO₄S
Boiling Point
Molecular Weight 239.252
Flash Point
Transport Information UN 2585 8/PG 3
Appearance White needle crystal
Safety 26-27-36/37/39
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms 2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-;7-amino-4-hydroxynaphthalene-2-sulfonic acid;Kyselina 2-amino-5-naftol-7-sulfonova;Kyselina 6-amino-1-naftol-3-sulfonova;2-Amino-5-naphthol-7-sulfonic acid;Aminonaphthol sulfonic acid J;Isogamma acid;BRN 2217192;CCRIS 8989;NSC 31510;Kyselina I;
PSA 109.00000
LogP 3.03630

Synthetic route

: 118-33-2
6-amino-naphthalene-1,3-disulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

Conditions

Conditions	Yield
durch Alkalischmelze;
With alkali at 180℃;

: 86-66-8
naphthalene-1,3,6-trisulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide anschliessend Erhitzen mit wss. Ammoniak und Schwefeldioxid;

: 118-33-2
6-amino-naphthalene-1,3-disulfonic acid

alkali: alkali

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

Conditions

Conditions	Yield
at 160 - 180℃;

: 110-86-1
pyridine

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 108-24-7
acetic anhydride

: 1069138-84-6
7-(acetylamino)-4-acetyloxynaphthalene-2-sulfonic acid pyridinium salt

Conditions

Conditions	Yield
at 20℃; for 16h;	99%

...Expand

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: C20H13N3O8S2(2-)*2Na(1+)

Conditions

Conditions	Yield
Stage #1: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1h; Stage #2: 7-amino-4-hydroxy-2-naphthalenesulfonic acid In water at 0 - 5℃; for 2h; pH=8 - 9;	93.2%

: 32315-10-9
bis(trichloromethyl) carbonate

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 134-47-4
AMI-1

Conditions

Conditions	Yield
With sodium hydroxide at 60℃; for 6h; pH=7 - 8;	90%

: 32315-10-9
bis(trichloromethyl) carbonate

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4-hydroxy-7-{[(5-hydroxy-7-sulfo-(2-naphthyl))amino]carbonylamino}naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide; sodium acetate In tetrahydrofuran; water	88%
With sodium acetate In tetrahydrofuran; sodium hydroxide; water

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: C7H5F2NO

: C17H11F2N3O5S

Conditions

Conditions	Yield
Stage #1: C7H5F2NO With hydrogenchloride; sodium nitrite In water at 0 - 5℃; Stage #2: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With sodium carbonate In water at 0 - 5℃; for 0.666667h; pH=7.5 - 8.5;	85%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 1392848-70-2
diphenyl (4'-aminobiphenyl-4-ylamino)(pyridin-3-yl)methylphosphonate

: 1392848-75-7
7-amino-8-((4'-((diphenoxyphosphoryl)(pyridin-3-yl)methylamino)biphenyl-4-yl)diazenyl)-4-hydroxynaphthalene-2-sulfonic acid

Conditions

Conditions	Yield
Stage #1: diphenyl (4'-aminobiphenyl-4-ylamino)(pyridin-3-yl)methylphosphonate With hydrogenchloride; sodium nitrite In water at 0℃; Stage #2: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With sodium hydroxide In water at 0℃; for 0.5h;	83%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: C8H8FNO2

: C18H14FN3O6S

Conditions

Conditions	Yield
Stage #1: C8H8FNO2 With hydrogenchloride; sodium nitrite In water at 0 - 5℃; Stage #2: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With sodium carbonate In water at 0 - 5℃; for 0.666667h; pH=7.5 - 8.5;	83%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 3-{4-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazoline-6-diazonium

: 7-Amino-3-(3-{4-[(E)-2-(2,4-dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo)-4-hydroxy-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium carbonate; sodium chloride In water 1.) 0-5 deg C, 3 h; 2.) 60 deg C;	79%

: 2494-89-5
2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate

: 108-77-0
1,3,5-trichloro-2,4,6-triazine

: 88-21-1
2-amino-1-benzenesulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 90-20-0
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid

: 88-63-1
2,4-Diaminobenzenesulfonic acid

: C43H27ClN12O23S7(6-)*6Na(1+)

Conditions

Conditions	Yield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 7-amino-4-hydroxy-2-naphthalenesulfonic acid With sodium hydroxide In water at 0 - 5℃; pH=5.6 - 6.5; Stage #2: With sodium carbonate In water at 3 - 5℃; for 5h; Stage #3: 2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate; 2-amino-1-benzenesulfonic acid; 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid; 2,4-Diaminobenzenesulfonic acid Further stages;	77.1%

...Expand

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 103-72-0
phenyl isothiocyanate

: 4-hydroxy-7-(N'-phenyl-thioureido)-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran at 20℃; for 12h;	75%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 62-53-3
aniline

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

Conditions

Conditions	Yield
With sodium metabisulfite at 100 - 110℃; pH=4-6; Reagent/catalyst;	70.2%
With sodium disulfite

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 103-71-9
phenyl isocyanate

: 4-hydroxy-7-(3-phenyl-ureido)-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran at 20℃; for 24h;	70%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 74-89-5
methylamine

: 22346-43-6
2-(N-methylamino)-5-hydroxynaphthalene-7-sulfonic acid

Conditions

Conditions	Yield
With sodium metabisulfite at 100 - 110℃; pH=7 - 8; Reagent/catalyst;	68.5%

: 4-chloro-3-nitrophenyl hydroxyethyl sulfone

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4-(5-hydroxy-7-sulfonaphth-2-yl)-amino-3-nitrophenyl hydroxyethyl sulfone

Conditions

Conditions	Yield
In water	60.6%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-Diaminostilbene dihydrochloride

: C34H24N6O8S2(2-)*2Na(1+)

Conditions

Conditions	Yield
Stage #1: 4,4'-Diaminostilbene dihydrochloride diazotization; Stage #2: 7-amino-4-hydroxy-2-naphthalenesulfonic acid	43%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 1608997-54-1
C6H3ClIN2(1+)*Cl(1-)

: 1608997-57-4
C22H12Cl2I2N5O4S(1-)*Na(1+)

Conditions

Conditions	Yield
With sodium hydroxide In water at 0℃; for 2h; pH=9;	42%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 57-13-6
urea

: 71550-28-2
2-ureylen-di-N,N'-4-hydroxynaphthalene-2-sulphonic acid monosodium salt

Conditions

Conditions	Yield
Stage #1: 7-amino-4-hydroxy-2-naphthalenesulfonic acid; urea In water at 100℃; for 16h; Inert atmosphere; Stage #2: With hydrogenchloride In water at 100℃; for 17h; Inert atmosphere;	15%

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 121-88-0
2-Amino-5-nitrophenol

: C16H12N4O7S

Conditions

Conditions	Yield
Stage #1: 5-Nitro-2-aminophenol With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1h; Stage #2: With aminosulfonic acid In water for 0.05h; Stage #3: 7-amino-4-hydroxy-2-naphthalenesulfonic acid In water at 10℃; for 2h;	1.3%

: 75-15-0
carbon disulfide

: 90-51-7
6-amino-4-hydroxy-2-naphthalenesulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-6,7'-thioureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With ethanol; sodium carbonate; sulfur

...Expand

: 75-15-0
carbon disulfide

: 489-78-1
1-amino-5-hydroxynaphthalene-7-sulphonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-7,8'-thioureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium carbonate; sulfur

...Expand

: 75-15-0
carbon disulfide

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-7,7'-thioureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With ethanol; sodium carbonate; sulfur

: 75-44-5
phosgene

: 90-51-7
6-amino-4-hydroxy-2-naphthalenesulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-6,7'-ureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium carbonate

...Expand

: 75-44-5
phosgene

: 489-78-1
1-amino-5-hydroxynaphthalene-7-sulphonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-7,8'-ureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With water; sodium carbonate

...Expand

: 75-44-5
phosgene

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 98-25-9
1-methyl-2,6-diaminobenzene-4-sulphonic acid

: 2,6-bis-[N'-(5-hydroxy-7-sulfo-[2]naphthyl)-ureido]-toluene-4-sulfonic acid

Conditions

Conditions	Yield
With water; sodium carbonate

...Expand

: 75-44-5
phosgene

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 134-47-4
AMI-1

Conditions

Conditions	Yield
With sodium carbonate

: 75-44-5
phosgene

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 6421-85-8
4-hydroxy-7-ureido-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With ammonia; water; sodium carbonate at 40 - 50℃;

: 527-69-5
2-furancarbonyl chloride

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 109258-06-2
7-(furan-2-carbonylamino)-4-hydroxy-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With diethyl ether; sodium acetate; sodium carbonate Reagens 4: Wasser;;

: 2684-02-8
benzenediazonium

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 83006-40-0
7-amino-4-hydroxy-3-phenylazo-naphthalene-2-sulfonic acid

: 14368-49-1
p-nitrobenzenediazonium

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 88247-02-3
7,8-diamino-4-hydroxy-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With acetic acid Reduktion des entstandenen Monoazofarbstoffs mit Zinn und Salzsaeure;

: 463-71-8
thiophosgene

: 90-51-7
6-amino-4-hydroxy-2-naphthalenesulfonic acid

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 4,4'-dihydroxy-6,7'-thioureylene-bis-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium carbonate

...Expand

J acid Consensus Reports

Reported in EPA TSCA Inventory.

J acid Specification

The 7-Amino-4-hydroxy-2-naphthalene sulfonic acid with CAS registry number of 87-02-5 is also known as 2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-. The IUPAC name is 7-Amino-4-hydroxynaphthalene-2-sulfonic acid. It belongs to product categories of Intermediates of Dyes and Pigments. Its EINECS registry number is 201-718-9. In addition, the formula is C₁₀H₉NO₄S and the molecular weight is 239.25. This chemical is a white needle crystal and should be sealed in cool, clean and dark room.

Physical properties about 7-Amino-4-hydroxy-2-naphthalene sulfonic acid are: (1)ACD/LogP: -1.46; (2)ACD/LogD (pH 5.5): -4.93; (3)ACD/LogD (pH 7.4): -4.98; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 4; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.748; (12)Molar Refractivity: 59.8 cm³; (13)Molar Volume: 147 cm³; (14)Surface Tension: 86.4 dyne/cm; (15)Density: 1.627 g/cm³.

Preparation of 7-Amino-4-hydroxy-2-naphthalene sulfonic acid: it is prepared by reaction of 2-naphthylamine-1-acid. Firstly, 2-naphthaleneate-5,7-disulfonmonosodiumate is obtained by sulfonation and hydrolysis. Then the reactant is melted in alkali and acidified to get product.

7-Amino-4-hydroxy-2-naphthalene sulfonic acid is prepared by reaction of 2-naphthylamine-1-acid.

Uses of 7-Amino-4-hydroxy-2-naphthalene sulfonic acid: it is used as dye intermediate and also used to produce 7-amino-3-(3-{4-[2-(2,4-dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo)-4-hydroxy-naphthalene-2-sulfonic acid by reaction with 3-{4-[2-(2,4-dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazoline-6-diazonium. The reaction occurs with reagents Na₂CO₃, NaCl and solvent H₂O. The yield is about 79%.

7-Amino-4-hydroxy-2-naphthalene sulfonic acid is used as dye intermediate and also used to produce 7-amino-3-(3-{4-[2-(2,4-dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo)-4-hydroxy-naphthalene-2-sulfonic acid by reaction with 3-{4-[2-(2,4-dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazoline-6-diazonium.

When you are using this chemical, please be cautious about it. As a chemical, it can cause burns. During using it, wear suitable protective clothing, gloves and eye/face protection. After using it, take off immediately all contaminated clothing. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C1=CC2=C(C=C(C=C2C=C1N)S(=O)(=O)O)O
2. InChI: InChI=1S/C10H9NO4S/c11-7-1-2-9-6(3-7)4-8(5-10(9)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)
3. InChIKey: KYARBIJYVGJZLB-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	oral	11500mg/kg (11500mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1057, 1986.

Product Name

J acid

Synthetic route

J acid Consensus Reports

J acid Specification

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