L-Glutamic acid supplier

Name
L-Glutamic acid (alpha)
EINECS 200-293-7
CAS No. 56-86-0
Article Data429
CAS DataBase
Density 1.41 g/cm³
Solubility 7.5 g/L (20 °C) in water
Melting Point 205 °C (dec.)(lit.)
Formula C₅H₉NO₄
Boiling Point 333.783 °C at 760 mmHg
Molecular Weight 147.131
Flash Point 155.667 °C
Transport Information
Appearance White cryst. powder
Safety 24/25-36-26
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 1-Aminopropane-1,3-dicarboxylic acid;2-Aminopentanedioic acid;2-Aminopentanedioic acid, (S)-;AI3-18472;Acide glutamique;Acido glutamico;Acidum glutamicum;Acidum glutaminicum;Aciglut;CCRIS 7314;D-Glutamiensuur;EPA Pesticide Chemical Code 374350;FEMA No. 3285;Glusate;Glutacid;Glutamate, L-;Glutamic acid (H-3);Glutamic acid (VAN);Glutamic acid, (S)-;Glutamicol;Glutamidex;Glutaminic acid;Glutaminic acid (VAN);Glutaminol;Glutaton;L-2-Aminoglutaric acid;L-Glutaminic acid;NSC 143503;Pentanedioic acid, 2-amino-, (S)-;UNII-3KX376GY7L;alpha-Aminoglutaric acid;alpha-Aminoglutaric acid (VAN);
PSA 100.62000
LogP -0.03660

Synthetic route

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With dimethylsulfide; hydrogen fluoride; methoxybenzene at 0℃; for 1h; Product distribution; Rate constant; other concentration of reagents;	100%
With dimethylsulfide; trifluorormethanesulfonic acid; 30 (v/v); trifluoroacetic acid at 0℃; for 4h; Yield given;
With trifluoroacetic acid In dichloromethane at 20℃; Rate constant;
With recombinant Pseudomonas nitroreducens IFO12694 γ-glutamyltranspeptidase at 30℃; for 0.0333333h; pH=10.5; aq. buffer; Enzymatic reaction;
With E. coli BL21 Star (DE3) S30 extract In aq. buffer at 37℃; for 6h; pH=7.5;

: 13574-13-5
Boc-Glu(OBzl)-OH

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With Nafion H; dimethylsulfide; 3-methyl-phenol; trifluoroacetic acid for 3h;	100%
With dimethylsulfide; hydrogen fluoride at 0℃; for 2h; Product distribution; Var.: HF in anisole;	100%

: 23506-06-1
Z(OMe)-Glu(OBzl)-OH

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; diphenyl sulfide In trifluoroacetic acid at 0℃; for 0.5h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed.;	100%

: 73821-97-3
N-α-tert-butyloxycarbonyl-glutamic acid, γ-cyclohexyl ester

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With phenylthiotrimethylsilane; pertrimethylsilylated Nafion; 3-methyl-phenol; trifluoroacetic acid for 3h;	100%

: 91871-28-2
N-allyloxycarbonyl α-allyl-L-glutamate

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With diethylamine; tetrakis(triphenylphosphine) palladium(0) In dichloromethane at 20℃; for 3h; deallylation;	100%

: 5680-86-4
N-benzyloxycarbonyl-5-O-benzyl-L-glutamic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With hydrogen In ethanol for 1.33333h;	98%
With hydrogen; hydroxyapatite-bound Pd In methanol at 40℃; for 12h;	96%
With hydrogen In ethanol at 20℃; under 760.051 Torr; for 3h;	95%

: 132316-96-2
(S)-(N-benzyl-N-benzyloxycarbonyl)glutamic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With hydrogen; palladium dihydroxide In water; acetic acid for 45h; Ambient temperature;	97%

: 13726-84-6
Boc-Glu(OtBu)-OH

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With triethylsilane; trifluoroacetic acid In dichloromethane for 1.08333h; Ambient temperature;	96%

: 2419-94-5
Boc-Glu

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With tetradecyl(trihexyl)phosphonium bistriflamide; trifluoroacetic acid at 130℃; for 0.166667h; Ionic liquid;	96%

: 98-79-3
L-Pyroglutamic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With sodium hydroxide; zinc(II) sulfate In water at 105℃; for 50h; Product distribution; Mechanism; Heating; at pH 6.5; variation of amount of substrate and added salts, reaction time and temperature; further metal salts;	93.1%
Rate constant;
Multi-step reaction with 7 steps 1.1: 100 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH2Cl2 / 0 - 20 °C 2.1: 100 percent / 3-chloroperoxybenzoic acid / CH2Cl2 / 4 h / 0 °C 3.1: bis(cyclopentadienyl)zirconium dichloride; silver(I) perchlorate / CH2Cl2 / 48 h 4.1: 9.40 g / 4-(dimethylamino)pyridine / acetonitrile / 1.5 h / 20 °C 5.1: sodium bis(trimethylsilyl)amide; N,N'-dimethylpropyleneurea / tetrahydrofuran / 0.5 h / -78 °C 5.2: tetrahydrofuran / 2 h 6.1: 6.48 g / hydrogen peroxide / tetrahydrofuran / 2 h / 20 °C 7.1: hydrogen / palladium on carbon / methanol 7.2: 77 percent / hydrochloric acid / Heating View Scheme

: 71989-18-9
Fmoc-Glu(OtBu)-OH

A: 56-86-0
L-glutamic acid

B: 2419-56-9
L-glutamic acid 5-tert-butyl ester

Conditions

Conditions	Yield
Stage #1: Fmoc-Glu(OtBu)-OH With sodium azide In N,N-dimethyl-formamide at 50℃; for 4h; Stage #2: With piperidine In N,N-dimethyl-formamide	A n/a B 92%

: (S)-3-(5'-oxo-9λ4-boraspiro[bicyclo[3.3.1]nonane-9,2'-[1,3,2]oxazaborolidin]-4'-yl)propanoic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; water at 20℃; for 7h;	88%

: 328-50-7
α-ketoglutaric acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With 1,4-dihydronicotinamide adenine dinucleotide; ethanol; ammonium chloride; adenosine 5'-diphosphate; L-glutamic dehydrogenase at 30℃; for 2h; tris-acetate buffer, pH 8.5;	86%
With ammonium; nicotinamide adenine dinucleotide phosphate; 2-hydroxyethanethiol; GluDH enzymes Mechanism; Irradiation; Tris buffer, 0.1 M, pH 7.9; Ru(bpy)3(2+), 2.2E-5 M as sensitizer;
With L-alanin In water at 25℃; Thermodynamic data; Equilibrium constant; biochemical transamination reaction by alanine aminotransferase; further transamination reagents: L-tyrosine, L-phenylalanine and further enzyme; pH 6.60-7.37; standard molar enthalpy, entropy, and Gibbs energy changes;

: 111-26-2
hexan-1-amine

: 78641-66-4
(S)-2-(3,5-Dinitro-4-oxo-4H-pyridin-1-yl)-pentanedioic acid

A: 56-86-0
L-glutamic acid

B: 74197-48-1
1-hexyl-3,5-dinitro-4-pyridone

Conditions

Conditions	Yield
In pyridine Product distribution;	A 84% B n/a

...Expand

: 97347-35-8
Boc-Gln(Boc)-Otert.Bu

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With trifluoroacetic acid for 0.166667h; Ambient temperature;	79%

: (S)-5-((1R,5R)-5-Methyl-2,6,8-trioxa-bicyclo[3.2.1]oct-1-yl)-1,5-dihydro-pyrrol-2-one

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
Stage #1: (S)-5-((1R,5R)-5-Methyl-2,6,8-trioxa-bicyclo[3.2.1]oct-1-yl)-1,5-dihydro-pyrrol-2-one With hydrogenchloride Heating; Stage #2: With Dowex 50W-X8	77%

: 570429-70-8
(5S)-1-tert-butoxycarbonyl-5-(5-methyl-2,7,8-trioxabicyclo[3.2.1]oct-1-yl)-5H-pyrrolin-2-one

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
Stage #1: (5S)-1-tert-butoxycarbonyl-5-(5-methyl-2,7,8-trioxabicyclo[3.2.1]oct-1-yl)-5H-pyrrolin-2-one With hydrogen; palladium on activated charcoal In methanol Stage #2: With hydrogenchloride Heating;	77%

: 1155-62-0
N-benzyloxycarbonyl-L-glutamic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With boron trichloride In dichloromethane at 25℃; for 0.333333h;	71%
With sulfuric acid at 50℃; Rate constant; other reaction partner, other temperature;
With hydrogen; palladium on activated charcoal In dichloromethane at 20℃; for 24h; atmospheric pressure;	41 mg
With ethylenediaminetetraacetic acid; phenylmethylsulphonyl fluoride; water In aq. phosphate buffer at 30℃; Kinetics; Reagent/catalyst; Microbiological reaction; Enzymatic reaction;

: C5H9NO4*H3N*ClH

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane	68%

: 13726-85-7
Boc-Gln-OH

: 76-05-1
trifluoroacetic acid

A: 56-86-0
L-glutamic acid

B: 98-79-3
L-Pyroglutamic acid

Conditions

Conditions	Yield
at 20℃; for 0.25h;	A 61% B 18%

...Expand

: 23632-67-9
(S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With boron trichloride In dichloromethane at 25℃; for 0.333333h;	58%

: 1188-38-1
L-carglumic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
With NH4Cl-NH4OH buffer pH 8.5; nickel dichloride at 60℃; for 24h; N-carbamyl-L-amino acid aminohydrolase;	56%
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 1h;
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 1h; pH 7.5; enzymatic reaction;

: (S)-2-((R)-2-Allyloxy-1-phenyl-ethylamino)-pentanedinitrile

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
Stage #1: (S)-2-((R)-2-Allyloxy-1-phenyl-ethylamino)-pentanedinitrile With palladium dihydroxide; hydrogen In ethanol at 20℃; under 76000 Torr; Stage #2: With hydrogenchloride; water at 100℃;	20%

: 328-50-7
α-ketoglutaric acid

: 56-41-7
L-alanin

A: 56-86-0
L-glutamic acid

B: 127-17-3
2-oxo-propionic acid

Conditions

Conditions	Yield
Gleichgewicht;
im lebenden tierischen Organismus;

...Expand

: 328-50-7
α-ketoglutaric acid

: 61-90-5
L-leucine

A: 816-66-0
4-methyl-2-oxopentanoic acid

B: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
in Gegenwart von Enzym-Praeparaten aus tierischen Geweben;
in Gegenwart von Enzym-Praeparaten aus Pflanzen;
in Gegenwart von Enzym-Praeparaten aus Torulopsis utilis;
With Erwinia carotovora subsp. carotovora aromatic aminotransferase PAT1 Enzymatic reaction;

...Expand

: 328-50-7
α-ketoglutaric acid

: 498-40-8
L-Cysteic acid

A: 56-86-0
L-glutamic acid

B: 98022-26-5
sulfo-pyruvic acid

Conditions

Conditions	Yield
in Gegenwart von Transaminase-Praeparaten aus Herzmuskel;

...Expand

: 56-85-9
L-glutamine

: 50-99-7
D-glucose

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
Einwirkung von Streptococcus-Arten.Hydrolysis;
Einwirkung von Proteus vulgaris.Hydrolysis;
Einwirkung von Proteus morganii.Hydrolysis;
Einwirkung von Staphylococcus.Hydrolysis;
Einwirkung von Saccharomyces cerevisiae.Hydrolysis;

: 56-85-9
L-glutamine

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
enzymatische Hydrolyse;
With Tris-HCl buffer; N74D Escherichia coli asparagine synthetase B mutant; BIS-TRIS; magnesium chloride at 37℃; pH=6.5; Enzyme kinetics; Hydrolysis;
With potassium dihydrogenphosphate at 25℃; pH=5.14; Thermodynamic data; Equilibrium constant; Hydrolysis;

: 617-65-2
Glutamic acid

: 56-86-0
L-glutamic acid

Conditions

Conditions	Yield
nach Verfuetterung an Kaninchen findet sich im Harn;
Bei der Einw. des Schimmelpilzes Penicillium purpurogenum;
Einw. von Penicillium glaucum;

: 67-56-1
methanol

: 56-86-0
L-glutamic acid

: 1499-55-4
L-glutamic acid 5-methyl ester

Conditions

Conditions	Yield
With chloro-trimethyl-silane at 20℃; for 0.25h; Inert atmosphere;	100%
With chloro-trimethyl-silane at 20℃;	97%
With chloro-trimethyl-silane at 20℃; for 0.166667h;	97%

: 67-56-1
methanol

: 56-86-0
L-glutamic acid

: 6525-53-7, 16422-27-8, 40149-68-6
L-glutamic acid dimethyl ester

Conditions

Conditions	Yield
With thionyl chloride	100%
With chloro-trimethyl-silane at 0 - 10℃; for 15h;	99.1%
With thionyl chloride at 0 - 20℃; for 12.5h; Inert atmosphere;	95%

: 67-56-1
methanol

: 56-86-0
L-glutamic acid

: 23150-65-4
L-glutamic dimethyl ester hydrochloride

Conditions

Conditions	Yield
Stage #1: methanol With thionyl chloride at 0℃; for 0.5h; Stage #2: L-glutamic acid at 21℃; for 72h; Inert atmosphere;	100%
With chloro-trimethyl-silane at 20℃;	99%
With chloro-trimethyl-silane at 20℃; for 16h;	98%

: 56-86-0
L-glutamic acid

: 56892-87-6
4-{[N-[(2,4-diamino-6-pteridinyl)methyl]-N-methyl]amino}benzoyl azide

: 59-05-2
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

Conditions

Conditions	Yield
With 1,1,3,3-tetramethylguanidine In dimethyl sulfoxide at 25℃; for 1h; Acylation;	100%

: 75-77-4
chloro-trimethyl-silane

: 56-86-0
L-glutamic acid

: 23150-65-4
L-glutamic dimethyl ester hydrochloride

Conditions

Conditions	Yield
In methanol at 20℃; for 16h;	100%

: 56-86-0
L-glutamic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 2419-94-5
Boc-Glu

Conditions

Conditions	Yield
With triethylamine In water; N,N-dimethyl-formamide for 1h;	100%
With triethylamine In water; acetone at 25℃; for 4.5h;	90%
Stage #1: L-glutamic acid With sodium hydroxide In water pH=11; Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 20℃; Cooling; Stage #3: With hydrogenchloride In tetrahydrofuran; water pH=2;	89%

: 56-86-0
L-glutamic acid

: 7646-85-7
zinc(II) chloride

: 12275-14-8
zinc glutamate

Conditions

Conditions	Yield
With sodium hydroxide In water at 5 - 20℃; for 18h; Heating / reflux;	100%

: 56-86-0
L-glutamic acid

: copper dichloride

: 911657-08-4, 69720-87-2
Cu(L-glutamate)

Conditions

Conditions	Yield
With sodium hydroxide In water at 5 - 20℃; for 24h; Heating / reflux;	100%

: 56-86-0
L-glutamic acid

: magnesium L-glutamate hydrochloride

Conditions

Conditions	Yield
Stage #1: L-glutamic acid With magnesium oxide In water at 60℃; for 1h; Stage #2: With magnesium chloride In water	100%
Stage #1: L-glutamic acid With magnesium oxide In water at 60℃; for 1h; Stage #2: With magnesium bromide In water	100%

: 56-86-0
L-glutamic acid

: 17720-18-2
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate (S)-2-ammonio-4-carboxybutanoate

Conditions

Conditions	Yield
In water pH=3.52; Cooling with ice;	100%

: 59-67-6
nicotinic acid

: 56-86-0
L-glutamic acid

: L-glutamic acid nicotinate

Conditions

Conditions	Yield
In water for 0.166667h; pH=Ca. 2.8 - 3.3; Cooling with ice;	100%

: 56-86-0
L-glutamic acid

: amphotericin B N-(2-aminoethyl)amide

: amphamide

Conditions

Conditions	Yield
In water for 0.25h;	100%
In water at 20℃; for 0.25h;

: 21205-91-4
9-borabicyclo[3.3.1]nonane dimer

: 56-86-0
L-glutamic acid

: C13H22BNO4

Conditions

Conditions	Yield
In methanol at 55℃; for 3h; Inert atmosphere;	100%

: 56-86-0
L-glutamic acid

: 2052-49-5
tetra(n-butyl)ammonium hydroxide

: (S)-1,1-dinaphthalene-2,2'-dicarboxaldehyde

: C32H24N2O8(4-)*4C16H36N(1+)

Conditions

Conditions	Yield
Stage #1: L-glutamic acid; tetra(n-butyl)ammonium hydroxide In methanol Stage #2: (S)-1,1-dinaphthalene-2,2'-dicarboxaldehyde In methanol at 20℃; for 72h; Molecular sieve;	100%

...Expand

: 56-86-0
L-glutamic acid

: 6674-22-2
1,8-diazabicyclo[5.4.0]undec-7-ene

: C5H9NO4*C9H16N2

Conditions

Conditions	Yield
In neat (no solvent) for 0.166667h; Green chemistry;	99.5%

: 56-86-0
L-glutamic acid

: 67-63-0
isopropyl alcohol

: 25975-47-7
diisopropyl (S)-glutamate

Conditions

Conditions	Yield
With sulfuric acid In toluene for 24h; Heating;	99%
With acetyl chloride at 110℃; for 1h;
Reflux;

: 56-86-0
L-glutamic acid

: 541-41-3
chloroformic acid ethyl ester

: 501-52-0
3-Phenylpropionic acid

A: 5700-75-4
C8H13NO6

B: N-(3-phenylpropanoyl)-L-Glu-OH

Conditions

Conditions	Yield
Stage #1: chloroformic acid ethyl ester; 3-Phenylpropionic acid With triethylamine In tetrahydrofuran at 0℃; for 0.5h; Stage #2: L-glutamic acid With sodium hydroxide In tetrahydrofuran; water at 0℃; for 0.5h; pH=7.5;	A n/a B 99%

...Expand

: 56-86-0
L-glutamic acid

: 75-36-5
acetyl chloride

: 1118-89-4
diethyl-L-glutamate hydrochloride

Conditions

Conditions	Yield
In ethanol at 0℃; for 4h; Reflux;	99%

: 56-86-0
L-glutamic acid

: 100-51-6
benzyl alcohol

: 4561-10-8
L-glutamic acid dibenzyl ester hydrochloride

Conditions

Conditions	Yield
Stage #1: L-glutamic acid; benzyl alcohol With thionyl chloride at 80 - 85℃; for 5h; Stage #2: With hydrogenchloride at 20 - 25℃; for 0.5h; Concentration; Temperature; Reagent/catalyst;	98.7%
With thionyl chloride at 5℃; for 5.33333h; Heating;	85%
Stage #1: L-glutamic acid; benzyl alcohol at 20 - 90℃; Stage #2: With sodium carbonate In water pH=10; Stage #3: With hydrogenchloride In diethyl ether

: 56-86-0
L-glutamic acid

: 501-53-1
benzyl chloroformate

: 1155-62-0
N-benzyloxycarbonyl-L-glutamic acid

Conditions

Conditions	Yield
With triethylamine In methanol for 3h;	98%
With sodium hydroxide In water at 0 - 20℃; for 6.5h;	98%
In water at 0℃; for 2h;	96%

: 67-56-1
methanol

: 56-86-0
L-glutamic acid

: L-glutamic acid methyl ester hydrochloride

Conditions

Conditions	Yield
With thionyl chloride at 20℃; for 24h;	98%
With thionyl chloride Ambient temperature;	89%

: 64-17-5
ethanol

: 56-86-0
L-glutamic acid

: 1118-89-4
diethyl-L-glutamate hydrochloride

Conditions

Conditions	Yield
With thionyl chloride	98%
Stage #1: ethanol; L-glutamic acid With bis(trichloromethyl) carbonate at 70 - 75℃; for 5h; Stage #2: With hydrogenchloride at 20 - 25℃; for 0.5h;	98%
Stage #1: ethanol With thionyl chloride at -10 - 10℃; for 1h; Stage #2: L-glutamic acid at 20 - 80℃; for 2h;	77.76%

: 56-86-0
L-glutamic acid

: 21461-84-7
(2S)-tetrahydro-5-oxofuran-2-carboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite In water at 15℃; optical yield given as %ee;	98%
With hydrogenchloride; water; sodium nitrite at 0 - 20℃; for 18h;	92%
With hydrogenchloride; sodium nitrite In water at -5 - 20℃; Inert atmosphere;	91.6%

: 56-86-0
L-glutamic acid

: 108-24-7
acetic anhydride

: 1188-37-0
N-acetyl-(S)-glutamic acid

Conditions

Conditions	Yield
In water for 0.0666667h; Irradiation;	98%
at 0 - 20℃;	61%
With water	58%
With acetic acid Heating;

: 56-86-0
L-glutamic acid

: 121-90-4
m-nitrobenzoic acid chloride

: 5420-67-7
N-(m-nitrobenzoyl)-L-glutamic acid

Conditions

Conditions	Yield
With chloro-trimethyl-silane; triethylamine In dichloromethane at 25℃; for 4h;	98%
Stage #1: L-glutamic acid With sodium hydrogencarbonate In water Stage #2: m-nitrobenzoic acid chloride In water; benzene at 10℃; for 1h; Further stages.;
With sodium carbonate In 1,4-dioxane; water at 20℃; for 12h;

L-Glutamic acid Consensus Reports

Reported in EPA TSCA Inventory.

L-Glutamic acid Specification

1. Introduction of L-Glutamic acid

L-Glutamic acid, with the IUPAC Name of (2S)-2-Aminopentanedioic acid, is one kind of white cryst. powder. This chemical belongs to the Product Categories which include Food & Feed ADDITIVES; chiral; Glutamic acid [Glu, E]; Amino Acids and Derivatives; alpha-Amino Acids; Amino Acids; Biochemistry; for Resolution of Bases; Optical Resolution; Synthetic Organic Chemistry; Nutritional Supplements; Amino Acids; Chiral Compound; Glutamate receptor; Glutamate; fine chemicals; glutamic acid; amino acid; bio-chemical; chemicals; food additive; food additives; nutritional supplement; organic acids; pharmaceutical intermediate.

2. Properties of L-Glutamic acid

L-Glutamic acid has the following property datas: (1)Melting point: 205 °C; (2)Index of Refraction: 1.522; (3)Molar Refractivity: 31.83 cm3; (4)Molar Volume: 104.3 cm3; (5)Surface Tension: 69.2 dyne/cm; (6)Density: 1.409 g/cm3; (7)Flash Point: 155.7 °C; (8)Enthalpy of Vaporization: 63.39 kJ/mol; (9)Boiling Point: 333.8 °C at 760 mmHg; (10)Vapour Pressure: 2.55E-05 mmHg at 25 °C; (11)storage temp.: Store at RT.; (12)solubility: 1 M HCl: 100 mg/mL; (13)Water Solubility: 7.5 g/L (20 °C).

3. Structure Descriptors of L-Glutamic acid

You could convert the following datas into the molecular structure:
InChI: InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKey: InChIKey=WHUUTDBJXJRKMK-VKHMYHEASA-N
Smiles: [C@H](CCC(=O)O)(C(=O)O)N

4. Toxicity of L-Glutamic acid

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TDLo	intravenous	117mg/kg (117mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	American Journal of the Medical Sciences. Vol. 214, Pg. 281, 1947.
human	TDLo	oral	71mg/kg (71mg/kg)	BEHAVIORAL: HEADACHE	Science. Vol. 163, Pg. 826, 1969.
rabbit	LD50	oral	> 2300mg/kg (2300mg/kg)		FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.
rat	LD50	oral	> 30gm/kg (30000mg/kg)		FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.

5. Safety Information of L-Glutamic acid
Hazard Codes of L-Glutamic acid (CAS NO.56-86-0): Irritant

Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25: Avoid contact with skin and eyes.
S36: Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: LZ9700000
F: 10
Human systemic effects by ingestion and intravenous routes: headache and nausea or vomiting. When heated to decomposition it emits toxic fumes of NO_x.

6. Production of L-Glutamic acid

L-Glutamic acid can be obtained directly from fermentation of carbohydrates with Micrococcus glutarnicus or Brevihacterium divaricatum.

Product Name

L-Glutamic acid (alpha)

Synthetic route

L-Glutamic acid Consensus Reports

L-Glutamic acid Specification

Related Products

Hot Products