Nitrilotriacetic acid supplier

Name
Nitrilotriacetic acid
EINECS 205-355-7
CAS No. 139-13-9
Article Data37
CAS DataBase
Density 1.61 g/cm³
Solubility Insoluble. <0.01 g/100 mL at 23 ºC
Melting Point 246 ºC
Formula C₆H₉NO₆
Boiling Point 498.2 ºC at 760 mmHg
Molecular Weight 191.141
Flash Point 255.1 ºC
Transport Information
Appearance white powder
Safety 26-45-36/37/39-53
Risk Codes 40-36/37/38-45-20/21/22
Molecular Structure
Hazard Symbols Xn,T
Synonyms Aceticacid, nitrilotri- (8CI);Complexon I;N,N-Bis(carboxymethyl)glycine;NSC 2121;NTA;Nitrilo-2,2',2''-triacetic acid;Nitrilo-N,N,N-triacetic acid;Nitrilotris(methylenecarboxylic acid);Titriplex I;Tris(hydroxycarbonylmethyl)amine;Versene NTA acid;a,a',a''-Trimethylaminetricarboxylic acid;
PSA 115.14000
LogP -1.45780

Synthetic route

: 79-11-8
chloroacetic acid

: 56-40-6
glycine

A: 139-13-9
nitrilotriacetic acid

B: 142-73-4
iminodiacetic acid

Conditions

Conditions	Yield
With lithium hydroxide for 144h; Ambient temperature;	A 12.5 g B 39%
With lithium hydroxide for 6h; Ambient temperature;	A 12.5 g B 39%

...Expand

: 50-00-0
formaldehyd

: 19522-69-1
N-butylethylenediamine

: 143-33-9
sodium cyanide

A: 139-13-9
nitrilotriacetic acid

B: 73264-08-1
N-[2-(bis-carboxymethyl-amino)-ethyl]-N-butyl-glycine

Conditions

Conditions	Yield
With sodium hydroxide; tert-butyl alcohol

...Expand

: 50-00-0
formaldehyd

: 151-50-8
potassium cyanide

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With ammonia; water
With water

: 50-00-0
formaldehyd

: 151-50-8
potassium cyanide

A: 79-14-1
glycolic Acid

B: 139-13-9
nitrilotriacetic acid

C: 56-40-6
glycine

D: 142-73-4
iminodiacetic acid

...Expand

: 7327-60-8
nitrilotriacetonitrile

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; water
With barium dihydroxide

: 19247-05-3
N,N-dicarboxymethyl hydrazine

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With sulfuric acid at 150℃;

: 79-11-8
chloroacetic acid

: 56-40-6
glycine

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With potassium hydroxide at 80℃;

: 79-11-8
chloroacetic acid

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With ammonia; water anschliessend mit NaCN und Formaldehyd;
With ammonia
With ammonia; zinc(II) chloride
With ammonia

: 50-00-0
formaldehyd

: 143-33-9
sodium cyanide

: 56-40-6
glycine

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With sodium hydroxide

...Expand

: 64-69-7
Iodoacetic acid

: 56-40-6
glycine

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With potassium hydroxide at 80℃;

: 56-40-6
glycine

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With water; mercury dichloride at 37℃;

: 3926-62-3
sodium monochloroacetic acid

: 142-73-4
iminodiacetic acid

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With sodium hydroxide; nitric acid Kinetics; Rate constant; Thermodynamic data;
With sodium hydroxide; nitric acid

: ammonium hydroxide

: 79-11-8
chloroacetic acid

A: 139-13-9
nitrilotriacetic acid

B diglycolamic acid: diglycolamic acid

Conditions

Conditions	Yield
pH >10 sinken;

...Expand

: 7664-41-7
ammonia

: 79-11-8
chloroacetic acid

A: 139-13-9
nitrilotriacetic acid

B: 56-40-6
glycine

C diglycolamic acid: diglycolamic acid

...Expand

: 79-11-8
chloroacetic acid

zinc chloride ammonia: zinc chloride ammonia

A: 139-13-9
nitrilotriacetic acid

B: 56-40-6
glycine

C diglycolamic acid: diglycolamic acid

Conditions

Conditions	Yield
durch Schmelzen;

...Expand

: 7732-18-5
water

: 56-40-6
glycine

HgCl2: HgCl2

A: 139-13-9
nitrilotriacetic acid

B: 7664-41-7
ammonia

C HgCl: HgCl

D diglycolamic acid: diglycolamic acid

Conditions

Conditions	Yield
at 40℃;
at 70℃;

...Expand

: 7327-60-8
nitrilotriacetonitrile

aq. barium hydroxide solution: aq. barium hydroxide solution

: 139-13-9
nitrilotriacetic acid

chloroacetic acid <3 mol>: chloroacetic acid <3 mol>

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With sodium hydroxide; ammonia

: 64-69-7
Iodoacetic acid

: 56-40-6
glycine

diluted KOH: diluted KOH

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
reagiert analog mit Cystin und mit p-Phenylendiamin;

...Expand

: 19247-05-3
N,N-dicarboxymethyl hydrazine

sulfuric acid (30 percent ): sulfuric acid (30 percent )

A: 139-13-9
nitrilotriacetic acid

B: 56-40-6
glycine

Conditions

Conditions	Yield
beim Erhitzen;

...Expand

: 7647-01-0
hydrogenchloride

: 7327-60-8
nitrilotriacetonitrile

A: 139-13-9
nitrilotriacetic acid

B: 142-73-4
iminodiacetic acid

...Expand

: 50-00-0
formaldehyd

: 74-90-8
hydrogen cyanide

: 7732-18-5
water

A: 79-14-1
glycolic Acid

B: 139-13-9
nitrilotriacetic acid

C diglycolamic acid: diglycolamic acid

Conditions

Conditions	Yield
Reaktion von KCN;

...Expand

: 50-00-0
formaldehyd

: 74-90-8
hydrogen cyanide

: 7732-18-5
water

A: 79-14-1
glycolic Acid

B: 139-13-9
nitrilotriacetic acid

C: 56-40-6
glycine

D diglycolamic acid: diglycolamic acid

Conditions

Conditions	Yield
Reaktion von KCN;

...Expand

: 1155-64-2
N6-[(benzyloxy)carbonyl]-L-lysine

: 79-08-3
bromoacetic acid

: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; palladium-carbon In sodium hydroxide; water

: 773837-37-9
sodium cyanide

: 50-00-0
formaldehyd

: 32221-81-1
monosodium glutamate

A: N,N-bis(carboxymethyl)glutamic acid tetrasodium salt

B: 139-13-9
nitrilotriacetic acid

Conditions

Conditions	Yield
Stage #1: sodium cyanide; monosodium glutamate With sodium hydroxide In water at 97℃; for 0.166667h; Strecker Synthesis; Stage #2: formaldehyd In water at 97℃; for 0.5h; Strecker Synthesis; Stage #3: sodium cyanide In water at 110℃; for 2h; Strecker Synthesis;	A 22 %Chromat. B n/a

...Expand

: 139-13-9
nitrilotriacetic acid

: 5856-63-3
(2R)-2-aminobutan-1-ol

: 911838-01-2
(+)-N,N,N-tris{[4-(R)-ethyloxazolin-2-yl]methyl}amine

Conditions

Conditions	Yield
Stage #1: nitrilotriacetic acid; (2R)-2-aminobutan-1-ol In toluene for 24h; Reflux; Stage #2: at 125℃; for 9h;	98%

: 139-13-9
nitrilotriacetic acid

: 1604046-86-7
S-trityl-L-penicillamine amide

: C78H81N7O6S3

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetonitrile at 0 - 20℃; for 16h; Inert atmosphere;	98%

: 108-77-0
1,3,5-trichloro-2,4,6-triazine

: 139-13-9
nitrilotriacetic acid

: C21H18N6O18(6-)*3Cl(1-)*9Na(1+)

Conditions

Conditions	Yield
Stage #1: nitrilotriacetic acid With sodium hydroxide In water for 0.5h; Stage #2: 1,3,5-trichloro-2,4,6-triazine In water; acetonitrile at 0 - 80℃; for 12h; Temperature; Solvent;	98%

: 108-77-0
1,3,5-trichloro-2,4,6-triazine

: 139-13-9
nitrilotriacetic acid

: C9H6Cl2N4O6(2-)*Cl(1-)*3Na(1+)

Conditions

Conditions	Yield
Stage #1: nitrilotriacetic acid With sodium hydroxide In water for 0.5h; Stage #2: 1,3,5-trichloro-2,4,6-triazine In water; acetonitrile at 0℃; for 2h; Temperature; Solvent;	98%

: 108-77-0
1,3,5-trichloro-2,4,6-triazine

: 139-13-9
nitrilotriacetic acid

: C15H12ClN5O12(4-)*2Cl(1-)*6Na(1+)

Conditions

Conditions	Yield
Stage #1: nitrilotriacetic acid With sodium hydroxide In water for 0.5h; Stage #2: 1,3,5-trichloro-2,4,6-triazine In water; acetonitrile at 0 - 40℃; for 6h; Temperature; Solvent;	98%

: 139-13-9
nitrilotriacetic acid

: 4253-34-3
methyltriacetoxysilane

: 1-methylsilatrane-3,7,10-trione

Conditions

Conditions	Yield
at 90 - 100℃; under 2 Torr; for 2h;	97%

: 139-13-9
nitrilotriacetic acid

: 42428-34-2
Phenyl-triethoxygerman

: 67-68-5
dimethyl sulfoxide

: (1-phenyl-2,8,9-trioxa-5-aza-1-germatricyclo[3.3.3.0(1,5)]undecane-3,7,10-trione) * DMSO

Conditions

Conditions	Yield
In dimethyl sulfoxide byproducts: CH3CH2OH; heated with stirring at 80°C for 15 min; excess of DMSO removed at 50°C; cooled; filtered off; washed (benzene and ether) dried (vac.); elem.anal.;	97%

...Expand

: sodium [99Tc]pertechnetate

: 139-13-9
nitrilotriacetic acid

: 5704-04-1
N-[tris(hydroxymethyl)methyl]glycine

: (99m)Tc(HYNIC-Lys(OMe)-NIC)(tricine)

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride In water at 100℃; for 0.166667h; pH=5.0; Succinate buffer;	95%

...Expand

: chromium chloride hexahydrate

: 139-13-9
nitrilotriacetic acid

: 7732-18-5
water

: barium carbonate

: [barium-di-mu.-hydroxy-bis-(nitrilotriacetatochromium(III))] heptahydrate

Conditions

Conditions	Yield
With NH4OH In water H2O added to a mixt. of ligand and dispersed BaCO3 (1:1.5), warmed up to95°C, treated with CrCl3*6H2O (1.5 equiv.) in H2O, kept at 95.de gree.C, neutralized with concd.NH4OH to pH=6.5-7; filtered, concd., crystd. for 24 h, filtered, washed (cold H2O, EtOH, ether);	95%

...Expand

: 110-86-1
pyridine

: 139-13-9
nitrilotriacetic acid

: 10026-10-5
uranium(IV) chloride

: (Hpy)2[U(nitrilotriacetate)2]

Conditions

Conditions	Yield
In pyridine onto UCl4 and nitrilotriacetic acid pyridine was condensed at -70°C, react. mixt. was stirred at 60°C for 30 min and at 95°C for 12 h; ppt. was filtered, washed with hot pyridine and dried under vacuum at 25°C for 48 h; elem. anal.;	95%

...Expand

: tetrabutoxytitanium

: zinc(II) sulfate heptahydrate

: 139-13-9
nitrilotriacetic acid

: 7722-84-1
dihydrogen peroxide

: [Zn(water)5]2[Ti2O(peroxide)2(nitrilotriacetate)2]*7water

Conditions

Conditions	Yield
With NH3 In ammonia aq. NH3; addn. of 1 equiv. of Ti(IV) compd. to soln. of 1 equiv. of nitrilotriacetic acid in H2O, stirring overnight, addn. of aq. H2O2 at 0°C, filtration, adjusting pH to 4.0 by aq. NH3, addn. of 1 equiv. of Zn(II) compd., keeping at 4°C for 3 ds; isolation of crystals, washing with deionized water, drying in vac., elem. anal.;	95%

...Expand

: 139-13-9
nitrilotriacetic acid

: 100-46-9
benzylamine

: 17612-75-8
2,2',2"-nitrilotris-(N-phenylmethyl)-acetamide

Conditions

Conditions	Yield
at 150℃; for 0.75h; microwave irradiation;	94%
Microwave irradiation;

: 139-13-9
nitrilotriacetic acid

: 1067-21-6
triethylmethoxystannane

: 87010-46-6
tris(triethylstannyl) nitrilotrisacetate

Conditions

Conditions	Yield
In not given elem. anal.;	94%

: 139-13-9
nitrilotriacetic acid

: 95-54-5
1,2-diamino-benzene

: 64019-57-4
N,N',N''-tris(2-benzimidazolylmethyl)amine

Conditions

Conditions	Yield
In ethylene glycol at 200℃;	93%
at 170 - 180℃; for 1h;	90%
In diethylene glycol	85%

: basic nickel carbonate tetrahydrate

: 139-13-9
nitrilotriacetic acid

: 7732-18-5
water

: 53927-84-7
H[Ni(nitrilotriacetato)(H2O)3]

Conditions

Conditions	Yield
In acetonitrile refluxed for 1 h; concd. (vac.), crystd. from H2O;	92%

...Expand

: tetrabutoxytitanium

: nickel(II) chloride hexahydrate

: 139-13-9
nitrilotriacetic acid

: 7722-84-1
dihydrogen peroxide

: [Ni(water)5]2[Ti2O(peroxide)2(nitrilotriacetate)2]*7water

Conditions

Conditions	Yield
With NH3 In ammonia aq. NH3; addn. of 1 equiv. of Ti(IV) compd. to soln. of 1 equiv. of nitrilotriacetic acid in H2O, stirring overnight, addn. of aq. H2O2 at 0°C, filtration, adjusting pH to 4.0 by aq. NH3, addn. of 1 equiv. of Ni(II) compd., keeping at 4°C for 3 ds; isolation of crystals, washing with deionized water, drying in vac., elem. anal.;	92%

...Expand

: 139-13-9
nitrilotriacetic acid

: CysC(C6H5)3(NH2)

: NTA(CysC(C6H5)3NH2)3

Conditions

Conditions	Yield
With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;	92%

: 166737-85-5
(2R)-2-Amino-3-(tritylsulfanyl)propanamide

: 139-13-9
nitrilotriacetic acid

: C72H69N7O6S3

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water; N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;	92%

: 139-13-9
nitrilotriacetic acid

: 7474-78-4
orthaminic acid

: C24H21N7O9S3

Conditions

Conditions	Yield
In ethylene glycol	92%

: 139-13-9
nitrilotriacetic acid

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 51407-32-0
1,1',1''-tris<(trimethylsiloxy)carbonyl>trimethylamine

Conditions

Conditions	Yield
	90%

: 139-13-9
nitrilotriacetic acid

: 153960-24-8
(3-dimethylaminopropyl)phenoxydiphenylstannane

: 5-(3-dimethylaminopropyl)triptychoxazastannolidone

Conditions

Conditions	Yield
In N,N-dimethyl-formamide byproducts: C6H6, C6H5OH; stirred and heated to 140°C (1 h); ppt. filtered off, washed (CH2Cl2), dried, elem. anal.;	90%

: tetrabutoxytitanium

: cobalt(II) chloride hexahydrate

: 139-13-9
nitrilotriacetic acid

: 7722-84-1
dihydrogen peroxide

: [Co(water)5]2[Ti2O(peroxide)2(nitrilotriacetate)2]*7water

Conditions

Conditions	Yield
With NH3 In ammonia aq. NH3; addn. of 1 equiv. of Ti(IV) compd. to soln. of 1 equiv. of nitrilotriacetic acid in H2O, stirring overnight, addn. of aq. H2O2 at 0°C, filtration, adjusting pH to 4.0 by aq. NH3, addn. of 1 equiv. of Co(II) compd., keeping at 4°C for 3 ds; isolation of crystals, washing with deionized water, drying in vac., elem. anal.;	90%

...Expand

: tetrabutoxytitanium

: 139-13-9
nitrilotriacetic acid

: 7722-84-1
dihydrogen peroxide

: 6080-56-4
lead(II) acetate trihydrate

: [Pb(H2O)3]2[nitrilotriacetatoperoxotitanate]*4H2O

Conditions

Conditions	Yield
In water Ti(O(CH2)3CH3)4 added to aq. suspn. of ligand, stirred for 3 h, H2O2 added at room temp. with stirring, Pb(CH3CO2)2*3H2O added, stirred for 0.5 h in air; filtered, washed with H2O, EtOH, dried in air; elem. anal.;	90%

...Expand

: 139-13-9
nitrilotriacetic acid

: 1095-85-8
2-amino tritylthio ethane

: 1449654-31-2
C69H66N4O3S3

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃;	90%

: 139-13-9
nitrilotriacetic acid

: 1356855-78-1, 811431-04-6
fac-[ReI(OH2)3(CO)3](SO3CF3)

: 1310-73-2
sodium hydroxide

: Na[fac-Re(CO)3(NTA)]

Conditions

Conditions	Yield
In water at 20℃; for 24h; pH=6 - 7;	89%

...Expand

: malachite

: 139-13-9
nitrilotriacetic acid

: H[Cu(nitrilotriacetato)(H2O)3]

Conditions

Conditions	Yield
In acetonitrile refluxed for 3 h; filtered immediately, crystd.; elem. anal.;	88%

: 139-13-9
nitrilotriacetic acid

: 401792-02-7
2-(aminomethyl)-1,6-dimethyl-3-(phenylmethoxy)-4(1H)-pyridinone

: 1346019-42-8
C51H57N7O9

Conditions

Conditions	Yield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃;	88%

: 139-13-9
nitrilotriacetic acid

: 5865-92-9
Ethyl-triethoxygermanium

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: (1-ethyl-2,8,9-trioxa-5-aza-1-germatricyclo[3.3.3.0(1,5)]undecane-3,7,10-trione) * DMF

Conditions

Conditions	Yield
In N,N-dimethyl-formamide; benzene byproducts: CH3CH2OH; boiled for 2 h with distillation; cooled; filtered off; washed (benzene and ether); dried (vac.); elem.anal.;	87%

...Expand

: 110-86-1
pyridine

: iron(III) chloride hexahydrate

: 139-13-9
nitrilotriacetic acid

: dipyridinium iron(III) nitriloacetato dichloride monohydrate

Conditions

Conditions	Yield
In pyridine nitrilotriacetic acid dissolved in refluxing pyridine, cooled slightly, FeCl3*6H2O added with stirring, 1.5 h; pyridine removed by exhaustive rotary evapn. over 0.5-1 h at 80°C, oil layered with MeCN, left overnight, ppt. washed with THF, dried in air;	87%
In pyridine ligand dissolved in refluxing py, cooled, ferric chloride (1:1) added, stirred for 1.5 h, concd.; layered (CH3CN), crystd., stored overnight, filtered off, washed (CH3CN,THF), elem. anal.;	83%

...Expand

: 139-13-9
nitrilotriacetic acid

: 5865-91-8
Methyl-triaethoxy-germanium

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: (1-methyl-2,8,9-trioxa-5-aza-1-germatricyclo[3.3.3.0(1,5)]undecane-3,7,10-trione) * DMF

Conditions

Conditions	Yield
In N,N-dimethyl-formamide; benzene byproducts: CH3CH2OH; boiled for 2 h with distillation; cooled; filtered off; washed (benzene and ether); dried (vac.); TG; elem.anal.;	86%

...Expand

Nitrilotriacetic acid Chemical Properties

Molecular Structure:

Molecular Formula: C₆H₉NO₆
Molecular Weight: 191.1388
IUPAC Name: 2-[Bis(carboxymethyl)amino]acetic acid
Synonyms of Aminotriacetic acid (CAS NO.139-13-9): 4-04-00-02441 (Beilstein Handbook Reference) ; AI3-52483 ; Acetic acid, nitrilotri- ; BRN 1710776 ; CCRIS 436 ; CHEL 300 ; Complexon I ; EINECS 205-355-7 ; Glycine, N,N-bis(carboxymethyl)- ; HSDB 2853 ; Hampshire NTA acid ; Komplexon I ; Kyselina nitrilotrioctova ; Kyselina nitrilotrioctova [Czech] ; N,N-Bis(carboxymethyl)glycine ; NCI-C02766 ; NSC 2121 ; NTA ; Nitrilo-2,2',2''-triacetic acid ; Nitrilotriacetic acid ; Nitrilotriessigsaeure ; Titriplex I ; Tri(carboxymethyl)amine ; Triglycine ; Triglycollamic acid ; Trilon A ; Versene NTA acid ; alpha,alpha',alpha''-Trimethylaminetricarboxylic acid
CAS NO: 139-13-9
Classification Code: Chelating agents ; Mutation data ; Tumor data
Melting point: 245 °C
Index of Refraction: 1.557
Molar Refractivity: 38.26 cm³
Molar Volume: 118.7 cm³
Surface Tension: 86.4 dyne/cm
Density: 1.61 g/cm³
Flash Point: 255.1 °C
Enthalpy of Vaporization: 83.9 kJ/mol
Boiling Point: 498.2 °C at 760 mmHg
Vapour Pressure: 2.78E-11 mmHg at 25°C

Nitrilotriacetic acid Uses

Aminotriacetic acid (CAS NO.139-13-9) is a very good fixing agent in the dye industry.And it is worked as , in the styrene production, stabilize the agent role and the role of catalyst and complexing agents, etc in the production of polyurethane foam.

Nitrilotriacetic acid Production

Aminotriacetic acid (CAS NO.139-13-9) can be produced by the reaction of chloroacetic acid and sodium hydroxide.And then amino Tri-sodium chloride reaction and acidification the product is finished.

Nitrilotriacetic acid Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	325mg/kg (325mg/kg)	CRC Critical Reviews in Toxicology. Vol. 20, Pg. 83, 1989.
mouse	LD50	oral	3160mg/kg (3160mg/kg)	Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rat	LD50	oral	1100mg/kg (1100mg/kg)	Angewandte Chemie, International Edition in English. Vol. 14, Pg. 94, 1975.

Nitrilotriacetic acid Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 48 (1990),p. 181.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 48 (1990),p. 181.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 48 (1990),p. 181.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-6 ,1977. . Reported in EPA TSCA Inventory. Community Right-To-Know List.

Nitrilotriacetic acid Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x.
Safety Information of Aminotriacetic acid (CAS NO.139-13-9):
Hazard Codes: Harmful Xn, Toxic T
Risk Statements: 40-36/37/38-45-20/21/22
R40: Limited evidence of a carcinogenic effect.
R36/37/38: Irritating to eyes, respiratory system and skin.
R45: May cause cancer.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-45-36/37/39-53
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S53: Avoid exposure - obtain special instructions before use.
RIDADR: 2811
WGK Germany: 2
RTECS: AJ0175000
F: 21
HazardClass: 8
PackingGroup: II
HS Code: 29224995

Nitrilotriacetic acid Specification

Stability and Reactivity of Aminotriacetic acid (CAS NO.139-13-9).
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials.
Incompatibilities with Other Materials Metals, strong oxidizing agents, strong bases.
Hazardous Decomposition Products Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization Will not occur.
First Aid Measures of Aminotriacetic acid (CAS NO.139-13-9).
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Handling and Storage of Aminotriacetic acid (CAS NO.139-13-9).
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Store in a tightly closed container.

Product Name

Nitrilotriacetic acid

Synthetic route

Nitrilotriacetic acid Chemical Properties

Nitrilotriacetic acid Uses

Nitrilotriacetic acid Production

Nitrilotriacetic acid Toxicity Data With Reference

Nitrilotriacetic acid Consensus Reports

Nitrilotriacetic acid Safety Profile

Nitrilotriacetic acid Specification

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