Pentafluoropyridine supplier

Name
Pentafluoropyridine
EINECS 211-839-9
CAS No. 700-16-3
Article Data43
CAS DataBase
Density 1.63 g/cm³
Solubility Not miscible or difficult to mix in water.
Melting Point -42 °C
Formula C₅F₅N
Boiling Point 100.1 °C at 760 mmHg
Molecular Weight 169.054
Flash Point 23.9 °C
Transport Information UN 1993 3/PG 3
Appearance clear colourless liquid
Safety 26-28-24/25-16
Risk Codes 10-20/21/22-36/37/38
Molecular Structure
Hazard Symbols Xn,F,Xi
Synonyms 2,3,4,5,6-Pentafluoropyridine;Pyridine,pentafluoro- (6CI,7CI,8CI,9CI);
PSA 12.89000
LogP 1.77710

Synthetic route

: 2176-62-7
2,3,4,5,6-pentachloropyridine

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
With potassium fluoride; B(2,2-bis(hydroxymethyl)propionate(3-)) In 1-methyl-pyrrolidin-2-one at 180℃; for 3h; Inert atmosphere;	84%
With potassium fluoride at 480℃; for 2h; Product distribution; various temperature, reactant volume, F(1-) ion concentration and contact time;

: potassium fluoride

: 2176-62-7
2,3,4,5,6-pentachloropyridine

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
In neat (no solvent) molar ratio C5Cl5N/KF = 1/20.0, 500 °C, 18 h;;	83%
In neat (no solvent) molar ratio C5Cl5N/KF = 1/20.0, 500 °C, 18 h;;	83%
In neat (no solvent) weight-ratio KF/C5Cl5N = 8/3, 450 °C, 24 h;;	68.5%

: 57310-43-7
4-N,N-dichloroamino-2,3,5,6-tetrafluoropyridine

A: 675-14-9
trifluoro-[1,3,5]triazine

B: 52026-98-9
4-chloro-2,3,5,6-tetrafluoropyridine

C: 700-16-3
Pentafluoropyridine

D: 75-69-4
trichlorofluoromethane

E: 667-42-5
2-chloro-3,3-difluoro-acrylonitrile

F: 13177-77-0
tetrafluoropyrazine

Conditions

Conditions	Yield
at 550℃; under 2 Torr; Mechanism; vacuum pyrolysis, other fluoropyridine compounds;	A n/a B 75% C n/a D n/a E n/a F n/a

...Expand

: potassium fluoride

: 2176-62-7
2,3,4,5,6-pentachloropyridine

A: 700-16-3
Pentafluoropyridine

B: 1735-84-8
3-chloro-2,4,5,6-tetrafluoropyridine

C: 1737-93-5
3,5-dichloro-2,4,6-trifluoropyridine

Conditions

Conditions	Yield
In neat (no solvent) autoclave, 470 °C (12 h), 2-fold molar excess of KF;;	A 65% B 18% C 5%
In neat (no solvent) autoclave, 470 °C (12 h), 2-fold molar excess of KF;;	A 65% B 18% C 5%
In neat (no solvent) 450 °C, excess of KF;;	A 40% B n/a C n/a

...Expand

: 1737-93-5
3,5-dichloro-2,4,6-trifluoropyridine

A: 700-16-3
Pentafluoropyridine

B: 1735-84-8
3-chloro-2,4,5,6-tetrafluoropyridine

Conditions

Conditions	Yield
With potassium fluoride; tetraphenylphosphonium bromide In sulfolane at 200℃; for 7h; Fluorination;	A 21% B 61%
With potassium fluoride In sulfolane; chlorobenzene at 215℃; for 22h;
With potassium fluoride; tetraphenylphosphonium bromide In sulfolane; chlorobenzene at 215℃; for 22h;

: potassium fluoride

: C5Cl2F3N

A: 700-16-3
Pentafluoropyridine

B: C5ClF4N

Conditions

Conditions	Yield
In sulfolane 223-227 °C (10 h);;	A 21% B 50%
In sulfolane 223-227 °C (10 h);;	A 21% B 50%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 3512-16-1
2,3,4,5-tetrafluoropyridine

C: 700-16-3
Pentafluoropyridine

D: 371-77-7
N,N-Bis(trifluoromethyl)amine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 395 - 405℃; for 0.5h; Further byproducts given;	A 32.9% B 3.9% C 39.9% D 8.5%
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 5.3% C 13.6% D 8.2%

...Expand

: 110-89-4
piperidine

: 2176-62-7
2,3,4,5,6-pentachloropyridine

A: 700-16-3
Pentafluoropyridine

B: 1735-84-8
3-chloro-2,4,5,6-tetrafluoropyridine

C: 1737-93-5
3,5-dichloro-2,4,6-trifluoropyridine

D: 34415-32-2
2,3,5,6-tetrachloro-4-fluoropyridine

Conditions

Conditions	Yield
With cesium fluoride In N,N-dimethyl-formamide at 80℃; for 9h; Product distribution; other reagents;	A 2% B 4% C 9% D 39%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 1513-66-2
2,3-difluoropyridine

C: 700-16-3
Pentafluoropyridine

D: 371-77-7
N,N-Bis(trifluoromethyl)amine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 2.2% C 13.6% D 8.2%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 3512-18-3
2,3,6-trifluoropyridine

C: 3512-16-1
2,3,4,5-tetrafluoropyridine

D: 700-16-3
Pentafluoropyridine

E: 371-77-7
N,N-Bis(trifluoromethyl)amine

F: tetrafluoro-3-(fluoromethyl)pyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Product distribution; other reactor geometry, temperature, time;	A 35.3% B 3.2% C 5.3% D 13.6% E 8.2% F 2.7%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 3512-18-3
2,3,6-trifluoropyridine

C: 700-16-3
Pentafluoropyridine

D: 371-77-7
N,N-Bis(trifluoromethyl)amine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 3.2% C 13.6% D 8.2%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 1513-65-1
2,6-difluoro pyridine

C: 700-16-3
Pentafluoropyridine

D: 371-77-7
N,N-Bis(trifluoromethyl)amine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 1.6% C 13.6% D 8.2%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 700-16-3
Pentafluoropyridine

C: 371-77-7
N,N-Bis(trifluoromethyl)amine

D: 84477-04-3
2,3,4-trifluoropyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 13.6% C 8.2% D 2.3%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 700-16-3
Pentafluoropyridine

C: 371-77-7
N,N-Bis(trifluoromethyl)amine

D: 84476-99-3
2,5-difluoropyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 13.6% C 8.2% D 2.1%

...Expand

: 110-86-1
pyridine

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 700-16-3
Pentafluoropyridine

C: 371-77-7
N,N-Bis(trifluoromethyl)amine

D: tetrafluoro-3-(fluoromethyl)pyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given;	A 35.3% B 13.6% C 8.2% D 2.7%

...Expand

: 836-77-1
perfluoro-N-fluoropiperidine

: 7439-89-6
iron

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
In neat (no solvent) Defluorination with oxide-free Fe at 580-610 °C/ > 1 Torr (dwell time 17 s);;	26%
In neat (no solvent) Defluorination with oxide-free Fe at 580-610 °C/ > 1 Torr (dwell time 17 s);;	26%
In neat (no solvent) Defluorination with oxide-free Fe at 580-610 °C/ > 1 Torr (dwell time 1 s).;	> 20
In neat (no solvent) Defluorination with oxide-free Fe at 580-610 °C/ > 1 Torr (dwell time 1 s).;	> 20

: 836-77-1
perfluoro-N-fluoropiperidine

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
With steel wool In neat (no solvent) 550 °C (40 min), steel tube filled with steel wool;;	19%
With steel wool In neat (no solvent) 550 °C (40 min), steel tube filled with steel wool;;	19%
With steel wool In neat (no solvent) 600 °C (95 min), steel tube filled with steel wool;;	18%

: 836-77-1
perfluoro-N-fluoropiperidine

: 7440-02-0
nickel

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
In gaseous matrix Defluorination in N2 atmosphere (flow rate 4l/h) at 560 °C/760 Torr.;	12%

: 2176-62-7
2,3,4,5,6-pentachloropyridine

A: 700-16-3
Pentafluoropyridine

B: C5Cl3F2N

C: C5Cl4FN

D: C5ClF4N

Conditions

Conditions	Yield
With KF-KCl melt In neat (no solvent) Inlet of the formed C5F3Cl2N (3g/10 min) at 645 °C into the KF-KCl melt (carrier gas = Ar, flow rate 70 ml/min), yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 7% B n/a C n/a D n/a
With KF-KCl melt In neat (no solvent) Inlet of the formed C5F3Cl2N (3g/10 min) at 645 °C into the KF-KCl melt (carrier gas = Ar, flow rate 70 ml/min), yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 7% B n/a C n/a D n/a

...Expand

: 109-06-8
α-picoline

A: 700-16-3
Pentafluoropyridine

B: 371-77-7
N,N-Bis(trifluoromethyl)amine

C: 78159-15-6
1-pentafluoroethyl-octafluoropyrrolidine

D: tetrafluoro-2-difluoromethylpyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) at 270℃; Further byproducts given;	A 1.9 g B 8.8 g C 1.7 g D 2%

...Expand

: 2176-62-7
2,3,4,5,6-pentachloropyridine

A: 700-16-3
Pentafluoropyridine

B: C5Cl2F3N

C: C5Cl3F2N

D: C5Cl4FN

E: C5ClF4N

Conditions

Conditions	Yield
With KF-KCl melt In neat (no solvent) Fluorination at 740 .degree C., yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 0.5% B n/a C n/a D n/a E n/a
With KF-KCl melt In neat (no solvent) Fluorination at 720 .degree C., yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 0.1% B n/a C n/a D n/a E n/a
With KF-KCl melt In neat (no solvent) Fluorination at 720 .degree C., yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 0.1% B n/a C n/a D n/a E n/a
With KF-KCl melt In neat (no solvent) Fluorination at 740 .degree C., yields of C5FnCl5-nN (n= 1 to 5) are indicated for the fluorination of the temperature range 630 - 740 °C;;	A 0.5% B n/a C n/a D n/a E n/a

...Expand

: 110-86-1
pyridine

A: 700-16-3
Pentafluoropyridine

B: 54471-09-9
4H,5H-heptafluoro-2-azahex-2(Z),4(E)-diene

C: 54471-08-8
5H-decafluoro-2-azahex-2(Z)-ene

D: 54471-05-5
undecafluoro-2-azahex-2(Z)-ene

Conditions

Conditions	Yield
With potassium tetrafluorocobaltate In gaseous matrix at 215 - 225℃; 1.) 3.5-4 h; 2.) 2 h; Further byproducts given;

...Expand

: 109-06-8
α-picoline

A: 2344-10-7
perfluoro-N-ethylpyrrolidine

B: 3146-94-9
2,3,4,5-tetrafluoro-6-(trifluoromethylpyridine)

C: 700-16-3
Pentafluoropyridine

D: 371-77-7
N,N-Bis(trifluoromethyl)amine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) at 270℃; Further byproducts given. Title compound not separated from byproducts;	A n/a B 1.4 g C 1.9 g D 8.8 g

...Expand

: 109-06-8
α-picoline

A: 3146-94-9
2,3,4,5-tetrafluoro-6-(trifluoromethylpyridine)

B: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
iron 1.) fluorination 2.) defluorination, 525 deg C; Yield given. Yields of byproduct given;
iron 1.) fluorination, 2.) defluorination, 525 deg C; Yield given. Yields of byproduct given;

: 109-06-8
α-picoline

A: 3146-94-9
2,3,4,5-tetrafluoro-6-(trifluoromethylpyridine)

B: 700-16-3
Pentafluoropyridine

C: 371-77-7
N,N-Bis(trifluoromethyl)amine

D: 78159-15-6
1-pentafluoroethyl-octafluoropyrrolidine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) at 270℃; Further byproducts given;	A 1.4 g B 1.9 g C 8.8 g D 1.7 g

...Expand

: 109-06-8
α-picoline

A: 700-16-3
Pentafluoropyridine

B: 371-77-7
N,N-Bis(trifluoromethyl)amine

C: 78159-15-6
1-pentafluoroethyl-octafluoropyrrolidine

D: tetrafluoro-2-fluoromethylpyridine

Conditions

Conditions	Yield
With caesium tetrafluorocobaltate(III) at 270℃; Further byproducts given;	A 1.9 g B 8.8 g C 1.7 g D 0.72 g

...Expand

: C5F5N(1+)*AsF6(1-)

A: 700-16-3
Pentafluoropyridine

B: 51957-26-7
1-azaheptafluoro-1,3-cyclohexadiene

Conditions

Conditions	Yield
1) 0 deg C, 2) CH3CN; Multistep reaction;

: 56154-85-9
1-fluoromethyl-octafluoropyrrolidine

A: 3512-16-1
2,3,4,5-tetrafluoropyridine

B: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
iron at 520℃; Yield given. Yields of byproduct given;

: 56154-80-4
1-difluormethyl-octafluoropyrrolidine

: 700-16-3
Pentafluoropyridine

Conditions

Conditions	Yield
iron at 520℃; Yield given;

: 2314-97-8
iodotrifluoromethane

: 2,3,4,5,6-Pentafluoro-pyridine

A: 700-16-3
Pentafluoropyridine

B: C5F5N*CF3

C: 2314-97-8
trifluoro-iodo-methane radical anion

Conditions

Conditions	Yield
In gas at 36.9℃; Rate constant;

...Expand

: 700-16-3
Pentafluoropyridine

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 69585-26-8
4-pentafluorophenoxy-2,3,5,6-tetrafluoropyridine

Conditions

Conditions	Yield
With potassium fluoride; 18-crown-6 ether In acetonitrile at 80℃; for 1h; ratio of pentafluoropyridine and pentafluorophenol 1:0.1;	100%
With cesium fluoride In N,N-dimethyl-formamide at 80℃; for 1h; Product distribution; other reagents, time;	95%

: 700-16-3
Pentafluoropyridine

: 2875-18-5
2,3,5,6-tetrafluoropyridine

Conditions

Conditions	Yield
With [(bis(diisopropylphosphino)ethane)Ni(H)]2; triethylphosphine In 1,4-dioxane at 120℃; for 72h;	100%
With (1,3-dimethylimidazolin-2-ylidene)*AlH3 In benzene-d6 at 20℃; for 0.0833333h; Reagent/catalyst;	99%
With bis(cyclopentadienyl)dihydrozirconium; [{((2,6-dimethylphenyl)NC(methyl))2CH}AlH2] at 25℃; for 24h; Reagent/catalyst; Temperature; Inert atmosphere;	93%

: 700-16-3
Pentafluoropyridine

: 617-05-0
ethyl vanillate

: 199784-56-0
4-(2,3,5,6-tetrafluoropyridin-4-yl)oxy-3-methoxybenzoic acid, ethyl ester

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile for 12h;	100%

: 700-16-3
Pentafluoropyridine

: 142-25-6
N,N',N'-trimethylenediamine

: 1193367-04-2
C10H13F4N3

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0℃; regioselective reaction;	100%

: 700-16-3
Pentafluoropyridine

: 1446417-30-6
[Rh{Si(OEt)3}(PEt3)3]

: 1231760-58-9
[Rh(C6F5)(PEt3)3]

Conditions

Conditions	Yield
In (2)H8-toluene at -30.16℃; for 3h; Reagent/catalyst; Schlenk technique; Inert atmosphere;	100%

: 700-16-3
Pentafluoropyridine

: C30H70B2O4P3Rh

: C23H45F4NP3Rh

Conditions

Conditions	Yield
In benzene-d6 for 0.0833333h; Inert atmosphere;	100%

: 700-16-3
Pentafluoropyridine

: 951-87-1, 5700-60-7, 16635-95-3, 29841-69-8, 35132-20-8, 107133-00-6
meso-1,2-diphenyl-1,2-diaminoethane

: meso-N,N’-bis(2,3,5,6-tetrafluoropyridin-4-yl)-1,2-diphenylethane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 24h; Inert atmosphere; Reflux; regioselective reaction;	100%

: 700-16-3
Pentafluoropyridine

: 822-36-6
4-methyl-1H-imidazole

: 1-(2,3,5,6-tetrafluoropyridyl)-4-methylimidazole

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 20h;	100%

: 700-16-3
Pentafluoropyridine

: 110-89-4
piperidine

Conditions

Conditions	Yield
With water In aq. phosphate buffer at 25℃; for 7.5h; pH=2.7 - 3.2; Electrochemical reaction;	100%

: 700-16-3
Pentafluoropyridine

: 108-95-2
phenol

: 113521-62-3
2,3,5,6-tetrafluoro-4-phenoxypyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; regioselective reaction;	99.5%
Stage #1: phenol With cholin hydroxide In water at 20℃; for 0.25h; Stage #2: Pentafluoropyridine In water at 20℃; for 24h;	86%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 700-16-3
Pentafluoropyridine

: 2402-79-1
2,3,5,6-tetrachloropyridine

Conditions

Conditions	Yield
With hydrogen; potassium carbonate at 200℃; under 15001.5 Torr; for 2h; Autoclave;	99.2%

: 700-16-3
Pentafluoropyridine

: 1795-31-9
tris(trimethylsilyl) phosphite

: C11H18F4NO3PSi2

Conditions

Conditions	Yield
With nickel dichloride at 150℃; for 0.5h;	99%

: 700-16-3
Pentafluoropyridine

: N,N-bistrifluoromethylhydroxylamine sodium salt

: 78708-00-6
4-tetrafluoropyridine

Conditions

Conditions	Yield
In diethyl ether at 20℃; for 72h;	99%

: 110-91-8
morpholine

: 700-16-3
Pentafluoropyridine

: 185742-33-0
4-(2,3,5,6-tetrafluoropyridin-4-yl)morpholine

Conditions

Conditions	Yield
With triethylamine In dichloromethane at -7 - 20℃; Inert atmosphere; regioselective reaction;	99%
With triethylamine In tetrahydrofuran at 20℃; Inert atmosphere; regioselective reaction;	99%
In ethanol at 0℃; for 168h;	87%

: 700-16-3
Pentafluoropyridine

: 90-15-3
α-naphthol

: 901594-51-2
2,3,5,6-Tetrafluoro-4-(naphthalen-1-yloxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;	99%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 2767-91-1
4-morpholinopyridine

: 700-16-3
Pentafluoropyridine

: 943868-09-5
2',3',5',6'-tetrafluoro-4-(morpholin-4-yl)-[1,4]bipyridinyl-1-ylium fluoride

Conditions

Conditions	Yield
In ethyl acetate at 20℃; for 6h;	99%

: 700-16-3
Pentafluoropyridine

: 1309151-10-7
(2,4,6-triisopropylphenyl)ethynyl piperidine-1-carbodithioate

: 2-fluoro-2-(piperidin-1-yl)-4-(2,3,5,6-tetrafluoropyridin-4-yl)-5-(2,4,6-triisopropylphenyl)-1,3-dithiole

Conditions

Conditions	Yield
In 1,4-dioxane at 20℃; for 18h; Solvent; Inert atmosphere;	99%

: 700-16-3
Pentafluoropyridine

: 110-70-3
N,N`-dimethylethylenediamine

: 1256619-41-6
N,N’-dimethyl-N,N’-bis(2,3,5,6-tetrafluoropyridin-4-yl)-ethane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at -7 - 20℃; Inert atmosphere; regioselective reaction;	99%
With triethylamine In tetrahydrofuran Inert atmosphere; Reflux; regioselective reaction;	99%

: 700-16-3
Pentafluoropyridine

: 20439-47-8
(1R,2R)-1,2-diaminocyclohexane

: (R,R)-N,N’’-bis(2,3,5,6-tetrafluoropyridin-4-yl)cyclohexane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 24h; Inert atmosphere; Reflux; regioselective reaction;	99%

: 700-16-3
Pentafluoropyridine

: 540-38-5
4-Iodophenol

: 2,3,5,6-tetrafluoro-4-(4-iodophenoxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 16h;	99%

: 700-16-3
Pentafluoropyridine

: 626-02-8
3-Iodophenol

: 2,3,5,6-tetrafluoro-4-(3-iodophenoxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 16h;	99%

: 95-14-7
1,2,3-Benzotriazole

: 700-16-3
Pentafluoropyridine

: 39066-47-2
1-(tetrafluoro-4'-pyridyl)-benzotriazol-1,2,3=1-(Tetrafluor-4'-pyridyl)-benzotriazol-1,2,3

Conditions

Conditions	Yield
With copper 2-phenylcyclopropanecarboxylate; cetyltrimethylammonim bromide; potassium carbonate In toluene for 6h; Arylation; Heating;	98%

: 700-16-3
Pentafluoropyridine

: 109-76-2
Trimethylenediamine

: N1,N3-bis(perfluoropyridine-4-yl)propane-1,3-diamine

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 0.5h; Arylation;	98%
With triethylamine In tetrahydrofuran at 20℃; for 1h; Amination;	98%
In ethanol at 0℃; for 0.0833333h;	84%

: 700-16-3
Pentafluoropyridine

: 150-76-5
4-methoxy-phenol

: 901594-61-4
2,3,5,6-tetrafluoro-4-(4-methoxyphenoxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 16h;	98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 700-16-3
Pentafluoropyridine

: 135-19-3
β-naphthol

: 901594-53-4
2,3,5,6-tetrafluoro-4-[(naphthalen-2-yl)oxy]pyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;	98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 700-16-3
Pentafluoropyridine

: 208242-43-7
4-isocyano-1,1’-biphenyl

: (Z)-N-([1,1'-biphenyl]-4-yl)-2,4,5,6-tetrafluoronicotinimidoyl fluoride

Conditions

Conditions	Yield
In benzene at 35℃; Inert atmosphere; UV-irradiation; regioselective reaction;	98%

: 700-16-3
Pentafluoropyridine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (S,S)-N,N’-bis(2,3,5,6-tetrafluoropyridin-4-yl)-1,2-diphenylethane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 24h; Inert atmosphere; Reflux; regioselective reaction;	98%

: 2033-24-1
cycl-isopropylidene malonate

: 700-16-3
Pentafluoropyridine

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: C11H7F4NO4*C8H19N

Conditions

Conditions	Yield
In acetonitrile at 45℃; for 0.5h;	98%

...Expand

: 100-02-7
4-nitro-phenol

: 700-16-3
Pentafluoropyridine

: 83235-15-8
4-(4'-Nitrophenoxy)-2,3,5,6-tetrafluoropyridine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 16h;	97%
With potassium fluoride; 18-crown-6 ether In sulfolane at 80℃; for 1h;	84%
pyrographite; cesium fluoride In N,N-dimethyl-formamide at 80℃; for 5h;	97 % Chromat.

: 700-16-3
Pentafluoropyridine

: 100-51-6
benzyl alcohol

: 3,5,6-Trifluoropyridin-2,4-diol dibenzyl ether

Conditions

Conditions	Yield
Stage #1: benzyl alcohol With sodium hydride In tetrahydrofuran at 20℃; for 0.25h; Metallation; Stage #2: Pentafluoropyridine In tetrahydrofuran Etherification;	97%

Pentafluoropyridine Chemical Properties

Molecular structure of Pentafluoropyridine (CAS NO.700-16-3):

MF: C₅F₅N
MW: 169.052216 g/mol
EINECS: 211-839-9
Melting Point: -42
Density: 1.63 g/cm³
Flash Point: 23.9 °C
Enthalpy of Vaporization: 32.54 kJ/mol
Boiling Point: 100.1 °C at 760 mmHg
Vapour Pressure: 42.8 mmHg at 25°C
IUPAC Name: 2,3,4,5,6-pentafluoropyridine
Chemical Properties of Pentafluoropyridine (CAS NO.700-16-3): Clear colourless loquid
Product Categories: Pyridines, Pyrimidines, Purines and Pteredines ; Pyridine ; Fluoropyridines ; Halopyridines ; C5 ; Heterocyclic Building Blocks ; Pyridines

Pentafluoropyridine Safety Profile

Safety Information of Pentafluoropyridine (700-16-3):
Hazard Codes Xn,F,Xi
Xn: Harmful Xi: Irritant C: Corrosive
Risk Statements: 10-20/21/22-36/37/38
10: Flammable
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-28-24/25-16
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
24/25: Avoid contact with skin and eyes
16: Keep away from sources of ignition - No smoking
RIDADR UN 1993 3/PG 3
WGK Germany: 3
Hazard Note: Flammable/Irritant
HazardClass: 3
PackingGroup: III

Pentafluoropyridine Specification

Pentafluoropyridine , its CAS NO. is 700-16-3, the synonyms are 2,3,4,5,6- Pentafluoropyridine ; Pentafluoropyridine ; Perfluoropyridine ; Pentafluoropyridine, 99+% ; Pentafluoropyridine 99% ; 5-Chloro-2-caynopyridine .

Product Name

Pentafluoropyridine

Synthetic route

Pentafluoropyridine Chemical Properties

Pentafluoropyridine Safety Profile

Pentafluoropyridine Specification

Related Products

Hot Products