DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:102767-28-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWe are very compeitive on Levetiracetam.Our mfr is GMP certified for this item with CEP document. Product Name: Levetiracetam CAS: 102767-28-2 MF: C8H14N2O2
Cas:102767-28-2
Min.Order:1 Kilogram
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Type:Trading Company
inquiryItems Standard Result Appearance White or almost white powder White powder Assay 98.0%-102.0%
Cas:102767-28-2
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Manufacturers
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:102767-28-2
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inquirySpecifications 1.good quality 2.high puriy 3.best service 1.Base Date Name:Levetiracetam CAS No.:102767-28-2 Molecular formular:C8H14N2O2 Levetiracetam Chemica
Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
Cas:102767-28-2
Min.Order:10 Gram
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:102767-28-2
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White or almost white powder Storage:Store at RT. Package
Cas:102767-28-2
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FOB Price: $100.0 / 150.0
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inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:102767-28-2
Min.Order:1 Gram
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Type:Manufacturers
inquiry1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE Appearance:white crystalline powder Storage:in cool Package:as request Application:active pharmaceutical ingredient Transportation:Air / SEA BOTH OK Port:
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:102767-28-2
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryColorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:102767-28-2
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Type:Manufacturers
inquiryName:Levetiracetam CAS NO:102767-28-2 Grade:Medical scientific research and export Molecular formula:C8H14N2O2 Molecular weight:170.209 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability D
Cas:102767-28-2
Min.Order:25 Kilogram
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:102767-28-2
Min.Order:1 Metric Ton
FOB Price: $0.9 / 1.0
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:102767-28-2
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:102767-28-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:102767-28-2
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Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:102767-28-2
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Type:Trading Company
inquiryName: Levetiracetam Synonyms: (S)-2-(2-Oxopyrrolidin-1-yl)butanamide CAS no: 102767-28-2 MF: C8H14N2O2 MW: 170.21 Usage: It an anticonvulsant medication used to treat epilepsy. Appearance:White powder Storage:Store in cool and dry place, awa
1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;
Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua
Cas:102767-28-2
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1. We are one of the domestic largest manufacturers of API; 2. We are always supplier of products with higher quality and at more competitive price; 3. We are supplier of safe and ecofriendly products ; 4. We provide stable supply and efficie
Cas:102767-28-2
Min.Order:25 Kilogram
Negotiable
Type:Trading Company
inquiryWe are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of Levetiracetam from Wuhan, Hubei, China. It is made obtai
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:102767-28-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:102767-28-2
Min.Order:1 Kilogram
FOB Price: $160.0
Type:Trading Company
inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
Cas:102767-28-2
Min.Order:1 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiry1-((S)-1-carbamoylpropyl)-2-oxopyrrolidine-3-carboxylic acid methyl ester
levetiracetam
Conditions | Yield |
---|---|
With water; sodium chloride In N,N-dimethyl-formamide at 130 - 140℃; for 18h; Product distribution / selectivity; | 100% |
In 4-methyl-2-pentanone at 115 - 120℃; for 12h; Product distribution / selectivity; | 52% |
levetiracetam
Conditions | Yield |
---|---|
With C68H72Cl2Co2P4; hydrogen In methanol at 50℃; Reagent/catalyst; enantioselective reaction; | 99.9% |
levetiracetam
Conditions | Yield |
---|---|
With hydrogen; triethylamine; palladium on activated charcoal In ethanol under 2587.71 Torr; for 2h; | 91% |
(S)-2-amino-butanamide hydrochloride
4-Chlorobutanoyl chloride
levetiracetam
Conditions | Yield |
---|---|
Stage #1: (S)-2-amino-butanamide hydrochloride With tetrabutylammomium bromide; sodium sulfate In dichloromethane at 0℃; for 0.5h; Stage #2: 4-Chlorobutanoyl chloride With potassium hydroxide In dichloromethane at 0℃; for 7h; | 89% |
Stage #1: (S)-2-amino-butanamide hydrochloride; 4-Chlorobutanoyl chloride With potassium hydroxide; sodium sulfate In acetonitrile at 3 - 5℃; for 5h; Stage #2: With hydrogenchloride pH=6; Product distribution / selectivity; | 84% |
With potassium hydroxide; tetrabutylammomium bromide; sodium sulfate; molecular sieve In dichloromethane; ethyl acetate; toluene | 74.1% |
(S)-2-amino-butanamide
4-Chlorobutanoyl chloride
levetiracetam
Conditions | Yield |
---|---|
Stage #1: (S)-2-amino-butanamide With tetrabutylammomium bromide; potassium hydroxide In dichloromethane at -15 - -5℃; for 2.25h; Stage #2: 4-Chlorobutanoyl chloride In dichloromethane at -10 - -8℃; | 85% |
butyl 4-chlorobutyrate
(S)-2-amino-butanamide hydrochloride
levetiracetam
Conditions | Yield |
---|---|
With triethylamine; sodium iodide In isopropyl alcohol at 90℃; for 36h; Inert atmosphere; | 85% |
(S)-α-ethyl-2-oxo-1-pyrrolidineacetic acid (R)-α-methylbenzylamine salt
levetiracetam
Conditions | Yield |
---|---|
Stage #1: (S)-α-ethyl-2-oxo-1-pyrrolidineacetic acid (R)-α-methylbenzylamine salt With sodium hydroxide In water for 0.5h; Stage #2: With chloroformic acid ethyl ester In dichloromethane at -10℃; for 2h; Stage #3: With ammonia In dichloromethane at -15 - -10℃; for 2h; Solvent; Reagent/catalyst; | 85% |
Multi-step reaction with 3 steps 1.1: sodium hydroxide; water / 0.5 h / 0 - 10 °C 1.2: pH 4 - 5 2.1: toluene-4-sulfonic acid / 7 h / 60 °C 3.1: ammonia / 24 h / 0 - 10 °C View Scheme |
4-chloro-butyric acid ethyl ester
(S)-2-amino-butanamide hydrochloride
levetiracetam
Conditions | Yield |
---|---|
With sodium carbonate; sodium iodide In dimethyl sulfoxide at 90℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; | 84% |
isopropyl 4-chlorobutanoate
(S)-2-amino-butanamide hydrochloride
levetiracetam
Conditions | Yield |
---|---|
With sodium carbonate; sodium iodide In N,N-dimethyl-formamide at 110℃; for 12h; Inert atmosphere; | 83% |
levetiracetam
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 82% |
levetiracetam
Conditions | Yield |
---|---|
With sodium tetrahydroborate; ethanol for 3h; Reflux; | 81% |
levetiracetam
Conditions | Yield |
---|---|
With potassium hydroxide In dichloromethane at -5 - 0℃; for 3h; Large scale; | 80.6% |
allyl 4-chlorobutyrate
(S)-2-amino-butanamide hydrochloride
levetiracetam
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 50℃; for 36h; Inert atmosphere; | 80% |
methyl 4-chlorobutyrate
(S)-2-amino-butanamide hydrochloride
levetiracetam
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In dimethyl sulfoxide at 100℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; | 80% |
(S)-2-(4-chlorobutyramido)butanamide
levetiracetam
Conditions | Yield |
---|---|
With potassium tert-butylate In tetrahydrofuran at 0 - 5℃; Reagent/catalyst; | 78.9% |
With potassium hydroxide at 20 - 25℃; for 2.5h; | 76.4% |
With potassium hydroxide; potassium iodide In tert-butyl methyl ether at 20℃; for 4h; Product distribution / selectivity; | |
With potassium hydroxide In tert-butyl methyl ether at 20℃; for 4h; Product distribution / selectivity; |
(2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid
levetiracetam
Conditions | Yield |
---|---|
Stage #1: (2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid With thionyl chloride In methanol at 45℃; Stage #2: With ammonia In methanol at 20℃; under 2250.23 Torr; Product distribution / selectivity; | 78.4% |
Stage #1: (2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid With chloroformic acid ethyl ester; triethylamine In tetrahydrofuran at 0℃; for 0.5h; Stage #2: With ammonium hydroxide In tetrahydrofuran for 16h; | 75% |
Stage #1: (2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid With ammonium hydroxide; triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.5h; Stage #2: With ammonium hydroxide In tetrahydrofuran at 20℃; for 11h; | 72% |
(S)-methyl 2-(2-oxopyrrolidin-1-yl)-2-butanoate
levetiracetam
Conditions | Yield |
---|---|
With ammonia In methanol at 20℃; under 2250.23 Torr; Product distribution / selectivity; Autoclave; | 78.4% |
With ammonia; water at 0 - 20℃; for 14h; Product distribution / selectivity; | 62.2% |
levetiracetam
Conditions | Yield |
---|---|
With methanol; potassium borohydride In dichloromethane for 8h; Reflux; | 78% |
chloroformic acid ethyl ester
(2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid
levetiracetam
Conditions | Yield |
---|---|
With ammonia; triethylamine In molecular sieve; dichloromethane; ethyl acetate; toluene | 72.3% |
Conditions | Yield |
---|---|
Stage #1: (S)-(+)-amino butynamide tartarate With potassium carbonate; sodium sulfate In acetonitrile at 0 - 5℃; Stage #2: 4-Chlorobutanoyl chloride In acetonitrile at 0 - 25℃; for 5h; Stage #3: With sodium hydroxide In acetonitrile at 0 - 5℃; for 10h; | 67% |
Conditions | Yield |
---|---|
Stage #1: (2S)-2-(2-oxopyrrolidin-1-yl)butanoic acid With chloroformic acid ethyl ester; triethylamine In tetrahydrofuran at 0℃; for 0.5h; Stage #2: With ammonium hydroxide In tetrahydrofuran; water at 20℃; for 16h; | A n/a B 65% |
Conditions | Yield |
---|---|
Stage #1: (R)-2-pyrrolidone-N-butyric acid With chloroformic acid ethyl ester; triethylamine In tetrahydrofuran at 0℃; for 0.5h; Stage #2: With ammonium hydroxide In tetrahydrofuran; water at 20℃; for 16h; | A 63% B n/a |
levetiracetam
Conditions | Yield |
---|---|
With sulfuric acid; water In dichloromethane at 100℃; for 0.166667h; Reagent/catalyst; Temperature; | 50% |
levetiracetam
Conditions | Yield |
---|---|
With sodium periodate; (x)H2O*O4Ru In ethyl acetate at 20℃; for 0.5h; Solvent; Electrochemical reaction; | 49% |
2,5-dihydro-2,5-dimethoxyfuran
(S)-2-amino-butanamide
levetiracetam
Conditions | Yield |
---|---|
Stage #1: 2,5-dihydro-2,5-dimethoxyfuran; (S)-2-amino-butanamide With hydrogenchloride In water at 20℃; for 1.5h; Stage #2: With sodium carbonate In water pH=8 - 9; Stage #3: With hydrogen; 5%-palladium/activated carbon In ethanol; water for 0.583333h; | 13% |
1-((S)-1-hydroxybutane-2-yl)pyrrolidin-2-one
levetiracetam
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 90 percent / 2,2,6,6-tetramethyl-1-piperidinyloxy; sodium hypochlorite; sodium chlorite / acetonitrile; aq. phosphate buffer / 6 h / 25 °C / pH 6.8 2.1: ethyl chloroformate; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 2.2: 75 percent / ammonium hydroxide / tetrahydrofuran / 16 h View Scheme | |
Multi-step reaction with 3 steps 1.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium chlorite; sodium hypochlorite / acetonitrile; aq. phosphate buffer / 7 h / 35 °C / pH 6.7 1.2: 0.75 h / 20 °C / pH 8 1.3: pH 3 - 4 2.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere 3.1: ammonium hydroxide / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium chlorite; sodium hypochlorite / acetonitrile; aq. phosphate buffer / 7 h / 35 °C / pH 6.7 1.2: 0.75 h / 20 °C / pH 8 1.3: pH 3 - 4 2.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere 3.1: ammonium hydroxide / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: potassium hydroxide; tetrabutylammomium bromide; potassium permanganate / water; dichloromethane / 12.5 h / 20 °C 2: triethylamine; chloroformic acid ethyl ester; ammonium hydroxide / water; tetrahydrofuran / 12.5 h / 0 - 20 °C View Scheme |
(S)-1-(1-(benzyloxy)butan-2-yl)pyrrolidin-2-one
levetiracetam
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: 97 percent / hydrogen / Pd/C / methanol / 6 h / 760 Torr 2.1: 90 percent / 2,2,6,6-tetramethyl-1-piperidinyloxy; sodium hypochlorite; sodium chlorite / acetonitrile; aq. phosphate buffer / 6 h / 25 °C / pH 6.8 3.1: ethyl chloroformate; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 3.2: 75 percent / ammonium hydroxide / tetrahydrofuran / 16 h View Scheme | |
Multi-step reaction with 4 steps 1.1: palladium(II) hydroxide; hydrogen / methanol / 24 h / 20 °C / 3102.97 Torr 2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium chlorite; sodium hypochlorite / acetonitrile; aq. phosphate buffer / 7 h / 35 °C / pH 6.7 2.2: 0.75 h / 20 °C / pH 8 2.3: pH 3 - 4 3.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere 4.1: ammonium hydroxide / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 4 steps 1.1: palladium(II) hydroxide; hydrogen / methanol / 24 h / 20 °C / 3102.97 Torr 2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium chlorite; sodium hypochlorite / acetonitrile; aq. phosphate buffer / 7 h / 35 °C / pH 6.7 2.2: 0.75 h / 20 °C / pH 8 2.3: pH 3 - 4 3.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere 4.1: ammonium hydroxide / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere View Scheme |
(αS,3S)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl 2-(2-oxopyrrolidin-1-yl)butyrate
levetiracetam
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 140 mg / LiOH*H2O; H2O2 / tetrahydrofuran / 7 h / 0 °C 2.1: (C2H5)3N; ethyl chloroformate / tetrahydrofuran / 0.5 h / 0 °C 2.2: 65 percent / ammonium hydroxide / tetrahydrofuran; H2O / 16 h / 20 °C View Scheme |
(αR,3S)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl 2-(2-oxopyrrolidin-1-yl)butyrate
levetiracetam
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 141 mg / LiOH*H2O; H2O2 / tetrahydrofuran / 7 h / 0 °C 2.1: (C2H5)3N; ethyl chloroformate / tetrahydrofuran / 0.5 h / 0 °C 2.2: ammonium hydroxide / tetrahydrofuran; H2O / 16 h / 20 °C View Scheme |
levetiracetam
(2S)-2-(2-oxo-1-pyrrolidinyl)butanenitrile
Conditions | Yield |
---|---|
With pyridine; p-toluenesulfonyl chloride In dichloromethane at 20℃; for 20h; | 93% |
oxalyl dichloride
(Z)-4-hydroxybut-2-enyl 1-(nitrooxy)ethyl carbonate
levetiracetam
(Z)-4-((1-(nitrooxy)ethoxy)carbonyloxy)but-2-enyl (S)-2-(2-oxopyrrolidin-1-yl)butanoylcarbamate
Conditions | Yield |
---|---|
Stage #1: oxalyl dichloride; levetiracetam In 1,1-dichloroethane; dichloromethane for 8h; Reflux; Stage #2: (Z)-4-hydroxybut-2-enyl 1-(nitrooxy)ethyl carbonate In 1,1-dichloroethane; dichloromethane at 20℃; for 12h; | 30.6% |
Hexanoyl chloride
levetiracetam
Conditions | Yield |
---|---|
Stage #1: levetiracetam With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Stage #2: Hexanoyl chloride In tetrahydrofuran; mineral oil at 0 - 20℃; for 16h; | 21% |
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