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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Ethyl 4-Chlorobutyrate supplier in China

Cas:3153-36-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

EAST CHEMSOURCES LIMITED

Founded in 2008, East Chemsources Limited is a professional manufacturer and supplier in food and chemical field in China. Through more than ten years development, our company has developed from single product at first to provide solution to final

ETHYL 4-CHLOROBUTYRATE

Cas:3153-36-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chlorobutyric acid ethyl ester

Cas:3153-36-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--3153-36-4--ETHYL 4-CHLOROBUTYRATE in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business rela

TIANFUCHEM--3153-36-4--ETHYL 4-CHLOROBUTYRATE in stock

Cas:3153-36-4

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Butanoic acid,4-chloro-, ethyl ester

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

ethyl 4-chlorobutanoate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Ethyl 4-Chloro Butyrate

Cas:3153-36-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Ethyl 4-chlorobutyrate, 98%

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Ethyl 4-Chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 3153-36-4 with competitive price

Cas:3153-36-4

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

ETHYL 4-CHLOROBUTYRATE 3153-36-4

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Other

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

ETHYL 4-CHLOROBUTYRATE

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

Ethyl 4-chlorobutanoate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Other

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

1. Certificate Of Analysis (COA) 2. Material Safety Data Sheet (MSDS) 3. Route of synthesis (ROS) 4. Method of Aanlysis (MOA) 5. Nuclear Magnetic Resonance (NMR) 6. Packing pictures and loading video before loading 7. Free Sample 9. F

ETHYL 4-CHLOROBUTYRATE 3153-36-4 C6H11ClO2

Cas:3153-36-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

ethyl 4-chlorobutanoate

Cas:3153-36-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Watson International Ltd

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

ETHYL 4-CHLOROBUTYRATE

Cas:3153-36-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen BaiFuchem Co.,Ltd

BaiFuChem is a Professional chemical raw material supplier in China, our main products include Biochemical , Pharma Intermediate and Organic chemical etc. BaiFuChem have wealth of products,experience , expertise and state-of-the-art

Best price Ethyl 4-Chlorobutyrate

Cas:3153-36-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

ETHYL 4-CHLOROBUTYRATE

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou KieRay Chem Co.,Ltd.

Hangzhou KieRaychem Co.,Ltd.is located in Yuhang District of Hangzhou City and specialized in the chemical product customization, development, sales, import and export. Current business is focused on fine chemicals, pharmaceutical materials and int

ETHYL 4-CHLOROBUTYRATE

Cas:3153-36-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Share Chemical Co., Ltd

At Share Chemical Company, we scrupulously abide by our policy of “Excellent Quality at a Reasonable Price”. We strive to satisfy all of our customers by providing the finest quality products supported by the finest in customer servi

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Cerametek Materials(ShenZhen)Co., Ltd.

Cerametek Materials (CMT) is your industrial and R&D supplier: 1. Semiconductor materials: Compounds of II, III, IV, V, VI groups such as Metal Sulfides, Selenides, Tellurides, Arsenide, Antimonide, Phosphide... 2. Advanced ceramic and crys

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Other

inquiry

Zouping Mingxing Chemical Co.,Ltd.

Appearance:standard Storage:dry,cool Package:UN Drum Transportation:by sea or air

Ethyl 4-chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai AngewChem Co., Ltd.

Shanghai AngewChemCo., Ltd. is an innovative enterprise on fine chemicals and pharmaceuticals. Based on Shanghai R&D center and Hunan chemical manufacturing plant, we offer chemical research, process development, and large-scale production. Complete

Ethyl 4-chlorobutanoate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan MoonZY Biological Technology Co.,Ltd

instock with good quality and offer wholesale priceAppearance:standard Storage:Keep in a cool & dry place Package:Packing material and QTY as your request Application:Pharma;Industry;other application Transportation:Express or as your request Port:A

Ethyl 4-Chlorobutyrate

Cas:3153-36-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride for 16h; Heating;80%
With hydrogenchloride
With hydrogenchloride
cyclobutanone
1191-95-3

cyclobutanone

oxovanadium(V) ethoxydichloride
1801-77-0

oxovanadium(V) ethoxydichloride

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With lithium chloride In diethyl ether for 13h; Ambient temperature;43%
ethyl 4-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate

ethyl 4-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate; 4-tert-Butylcatechol; 2-methoxybenzo[d][1,3,2]dioxaborole; trans-di-O-tert-butyl hyponitrite In methanol; dichloromethane; benzene at 70℃; for 16h; Inert atmosphere;30%
1,4-dioxane
123-91-1

1,4-dioxane

4-ethoxy-butyryl chloride
14077-66-8

4-ethoxy-butyryl chloride

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
at 70℃; Geschwindigkeit der Umlagerung verschiedener Konz.;
at 100℃; Geschwindigkeit der Umlagerung verschiedener Konz.;
4-butanolide
96-48-0

4-butanolide

ethanol
64-17-5

ethanol

A

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

B

4-(4-chloro-butyryloxy)-butyric acid ethyl ester

4-(4-chloro-butyryloxy)-butyric acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride
4-Chlorobutyronitrile
628-20-6

4-Chlorobutyronitrile

ethanol
64-17-5

ethanol

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride
With sulfuric acid
With hydrogenchloride
With hydrogenchloride In dichloromethane at 8℃;
ethanol
64-17-5

ethanol

4-(4-nitrophenoxy)butanoic acid
28341-54-0

4-(4-nitrophenoxy)butanoic acid

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride zuletzt bei Siedetemperatur;
4-ethoxy-butyryl chloride
14077-66-8

4-ethoxy-butyryl chloride

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
at 100℃;
at 100℃;
at 50℃; Geschwindigkeit der Umlagerung;
at 100℃; Geschwindigkeit der Umlagerung;
4-ethoxybutanoic acid
10374-37-5

4-ethoxybutanoic acid

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride
Multi-step reaction with 2 steps
1: hydrogen; SOCl2
2: 100 °C / Geschwindigkeit der Umlagerung
View Scheme
Multi-step reaction with 2 steps
1: hydrogen; SOCl2
2: 100 °C
View Scheme
butanoic acid ethyl ester
105-54-4

butanoic acid ethyl ester

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With tetrachloromethane; sulfuryl dichloride; dibenzoyl peroxide
γ-chlorobutyric acid
627-00-9

γ-chlorobutyric acid

ethanol
64-17-5

ethanol

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With sulfuric acid
With thionyl chloride at 0℃; for 2h; Reflux;
With acetyl chloride at 20℃; for 24h; Inert atmosphere;
cyclobutanone
1191-95-3

cyclobutanone

oxovanadium(V) ethoxydichloride
1801-77-0

oxovanadium(V) ethoxydichloride

acrylonitrile
107-13-1

acrylonitrile

A

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

B

ethyl 6-chloro-6-cyanohexanoate
132960-08-8

ethyl 6-chloro-6-cyanohexanoate

Conditions
ConditionsYield
With copper dichloride 1.) dichloromethane, -75 deg C, 2.) a) -75 deg C, 2 h, b) room temperature, 14-19 h; Yield given. Multistep reaction. Yields of byproduct given;
cyclobutanone
1191-95-3

cyclobutanone

oxovanadium(V) ethoxydichloride
1801-77-0

oxovanadium(V) ethoxydichloride

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

A

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

B

ethyl 6-chloro-6-(methoxycarbonyl)heptanoate
132960-09-9

ethyl 6-chloro-6-(methoxycarbonyl)heptanoate

Conditions
ConditionsYield
With copper dichloride 1.) dichloromethane, -75 deg C, 2.) a) -75 deg C, 2 h, b) room temperature, 14-19 h; Yield given. Multistep reaction. Yields of byproduct given;
cyclobutanone
1191-95-3

cyclobutanone

oxovanadium(V) ethoxydichloride
1801-77-0

oxovanadium(V) ethoxydichloride

methacrylonitrile
126-98-7

methacrylonitrile

A

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

B

ethyl 6-chloro-6-cyanoheptanoate
132960-07-7

ethyl 6-chloro-6-cyanoheptanoate

Conditions
ConditionsYield
With copper dichloride Product distribution; multistep reaction; other olefins, or LiCl, other halogen source, other cyclic carbonyl compound; oxidative ring-opening reaction;
With copper dichloride 1.) dichloromethane, -75 deg C, 2 h, 2.) a) -75 deg C, 2 h, b) room temperature, 17 h; Yield given. Multistep reaction. Yields of byproduct given;
ethanol
64-17-5

ethanol

4-Chlorobutanoyl chloride
4635-59-0

4-Chlorobutanoyl chloride

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

tetrachloromethane
56-23-5

tetrachloromethane

sulfuryl dichloride
7791-25-5

sulfuryl dichloride

butanoic acid ethyl ester
105-54-4

butanoic acid ethyl ester

dibenzoyl peroxide
94-36-0

dibenzoyl peroxide

A

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

B

ethyl 2-chlorobutyrate
7425-45-8

ethyl 2-chlorobutyrate

C

3-chloro-butyric acid ethyl ester
7425-48-1

3-chloro-butyric acid ethyl ester

thionyl chloride
7719-09-7

thionyl chloride

4-ethoxybutanoic acid
10374-37-5

4-ethoxybutanoic acid

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

5,11,17,23-tetra-tert-butyl-25,27-di(3-ethoxycarbonylpropoxy)-26,28-dihydroxycalix[4]arene
205995-80-8

5,11,17,23-tetra-tert-butyl-25,27-di(3-ethoxycarbonylpropoxy)-26,28-dihydroxycalix[4]arene

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
With titanium(IV) chloride tetrahydrofuran In toluene for 24h; Inert atmosphere; Reflux;
ethyl 3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-propionate
302577-73-7

ethyl 3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-propionate

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: n-butyllithium / tetrahydrofuran; diethyl ether / 16 h / -100 - 20 °C / Inert atmosphere
2: trimethylsilyl trifluoromethanesulfonate; 4-tert-Butylcatechol; trans-di-O-tert-butyl hyponitrite; 2-methoxybenzo[d][1,3,2]dioxaborole / dichloromethane; benzene; methanol / 16 h / 70 °C / Inert atmosphere
View Scheme
ethyl acrylate
140-88-5

ethyl acrylate

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: copper(II) carbonate; copper(II) hydroxide; triphenylphosphine / water / 0.5 h / 20 °C / Inert atmosphere
1.2: 16 h / 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; diethyl ether / 16 h / -100 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate; 4-tert-Butylcatechol; trans-di-O-tert-butyl hyponitrite; 2-methoxybenzo[d][1,3,2]dioxaborole / dichloromethane; benzene; methanol / 16 h / 70 °C / Inert atmosphere
View Scheme
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

ethyl 2-(benzylamino)acetate
6436-90-4

ethyl 2-(benzylamino)acetate

4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester
63876-32-4

4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In toluene for 8h; Solvent; Reflux; Large scale;99.1%
With potassium carbonate In chloroform at 66 - 68℃; for 24h;
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

N-Methyl-N-methoxy-4-chlorobutanamide
64214-66-0

N-Methyl-N-methoxy-4-chlorobutanamide

Conditions
ConditionsYield
With trimethylaluminum In hexane; dichloromethane for 24h; Ambient temperature;99%
Stage #1: N,O-dimethylhydroxylamine*hydrochloride With dimethyl aluminium chloride In hexane; dichloromethane at 0 - 20℃; for 1h;
Stage #2: 4-chloro-butyric acid ethyl ester In dichloromethane for 1h;
82%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-(3,4-dichloro)phenylpiperazine
57260-67-0

1-(3,4-dichloro)phenylpiperazine

ethyl 4-[4-(3,4-dichlorophenyl)piperazin-1-yl]butanoate
1061701-06-1

ethyl 4-[4-(3,4-dichlorophenyl)piperazin-1-yl]butanoate

Conditions
ConditionsYield
With cesium hydroxide; sodium iodide at 50℃; for 0.266667h; Microwave irradiation; Neat (no solvent); chemoselective reaction;98%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-(2,5-dimethylphenyl)piperazine
1013-25-8

1-(2,5-dimethylphenyl)piperazine

ethyl 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butanoate
1061701-76-5

ethyl 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butanoate

Conditions
ConditionsYield
With cesium hydroxide; sodium iodide at 50℃; for 0.266667h; Microwave irradiation; Neat (no solvent); chemoselective reaction;97%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-[3-(trifluoromethyl)phenyl]piperazine hydrochloride

1-[3-(trifluoromethyl)phenyl]piperazine hydrochloride

ethyl 4-[4-(3-(trifluoromethyl)phenyl)piperazin-1-yl]butanoate
108786-32-9

ethyl 4-[4-(3-(trifluoromethyl)phenyl)piperazin-1-yl]butanoate

Conditions
ConditionsYield
With cesium hydroxide; sodium iodide at 50℃; for 0.266667h; Microwave irradiation; Neat (no solvent); chemoselective reaction;97%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

5-nitroguaiacol
636-93-1

5-nitroguaiacol

ethyl 4-(2-methoxy-5-nitrophenoxy) butyrate
1093798-74-3

ethyl 4-(2-methoxy-5-nitrophenoxy) butyrate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃;96%
With potassium carbonate In N,N-dimethyl-formamide at 60℃;
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1,2,3-trimethoxybenzene
621-23-8

1,2,3-trimethoxybenzene

1-(4-chlorobutyl)-2,4,6-trimethoxybenzene

1-(4-chlorobutyl)-2,4,6-trimethoxybenzene

Conditions
ConditionsYield
With dimethylethylsilane; (μ3,η2,η3,η5-acenaphthylene)Ru3(CO)7 at 20℃; for 5h; Inert atmosphere; Neat (no solvent);96%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

octyl alpha-D-glucopyranoside
29781-80-4

octyl alpha-D-glucopyranoside

Octyl 6-O-4-chlorobutanoyl-α-D-glucopyranoside

Octyl 6-O-4-chlorobutanoyl-α-D-glucopyranoside

Conditions
ConditionsYield
With zeolite CaA at 40℃; for 48h; SP 435 lipase;95%
at 40℃; for 6h; Product distribution; lipase from Candida antarctica; other lipases, times; also in the presence of zeolite CaA;
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

ethyl 4-azidobutyrate
51453-79-3

ethyl 4-azidobutyrate

Conditions
ConditionsYield
With sodium azide; 15-crown-5 In acetonitrile for 12h; Heating;95%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-(4-Fluorophenyl)piperazine
2252-63-3

1-(4-Fluorophenyl)piperazine

ethyl 4-<4-(4-fluorophenyl)-1-piperazinyl>butyrate
130933-88-9

ethyl 4-<4-(4-fluorophenyl)-1-piperazinyl>butyrate

Conditions
ConditionsYield
With cesium hydroxide; sodium iodide at 50℃; for 0.266667h; Microwave irradiation; Neat (no solvent); chemoselective reaction;95%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1,8-Naphthalimide
81-83-4

1,8-Naphthalimide

ethyl 4-(1,3-dioxo-2,3-dihydro-1H-benzo[d,e]isoquinolin-2-yl)butanoate
150705-10-5

ethyl 4-(1,3-dioxo-2,3-dihydro-1H-benzo[d,e]isoquinolin-2-yl)butanoate

Conditions
ConditionsYield
With caesium carbonate; sodium iodide In N,N-dimethyl-formamide at 70℃; for 0.166667h; Microwave irradiation;95%
4-Cyanochlorobenzene
623-03-0

4-Cyanochlorobenzene

4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

4-cyano-benzenebutanoic acid ethyl ester
131379-33-4

4-cyano-benzenebutanoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 4-chloro-butyric acid ethyl ester With tetrabutylammomium bromide; iodine; zinc In N,N-dimethyl acetamide at 80℃; for 12h;
Stage #2: 4-Cyanochlorobenzene; bis(triphenylphosphine)nickel(II) chloride In N,N-dimethyl acetamide Further stages.;
94%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

2-methoxyethyl 4-chlorobutanoate

2-methoxyethyl 4-chlorobutanoate

Conditions
ConditionsYield
With titanium(IV) isopropylate In toluene at 20℃; Dean-Stark;94%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1,3-dimethyl glycerol ether
623-69-8

1,3-dimethyl glycerol ether

1,3-dimethoxypropan-2-yl 4-chlorobutanoate

1,3-dimethoxypropan-2-yl 4-chlorobutanoate

Conditions
ConditionsYield
With titanium(IV) isopropylate In toluene at 20℃; Dean-Stark;94%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

4-chloro-1-butanol-1,1-d2
66502-79-2

4-chloro-1-butanol-1,1-d2

Conditions
ConditionsYield
With lithium aluminium deuteride In diethyl ether -15 deg C -> 15 deg C; 15 deg C , 30 min;93%
With lithium aluminium deuteride In diethyl ether at -10℃;
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

7-methyl-3,3-diphenylindoline

7-methyl-3,3-diphenylindoline

ethyl 4-(7-methyl-3,3-diphenylindolin-1-yl)butanoate

ethyl 4-(7-methyl-3,3-diphenylindolin-1-yl)butanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 6h;92%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

5-methoxy-2-(3-phenylisoxazol-5-yl)phenol
1186130-66-4

5-methoxy-2-(3-phenylisoxazol-5-yl)phenol

ethyl 4-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)butanoate
1186130-80-2

ethyl 4-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)butanoate

Conditions
ConditionsYield
With potassium carbonate In acetone Williamson type O-alkylation; Reflux;90.5%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1,4-bis(piperazin-1-yl)-2,3,5,6-tetrafluorobenzene

1,4-bis(piperazin-1-yl)-2,3,5,6-tetrafluorobenzene

4-(4-{4-[4-(3-ethoxycarbonyl-propyl)-piperazin-1-yl]-2,3,5,6-tetrafluoro-phenyl}-piperazin-1-yl)-butyric acid ethyl ester

4-(4-{4-[4-(3-ethoxycarbonyl-propyl)-piperazin-1-yl]-2,3,5,6-tetrafluoro-phenyl}-piperazin-1-yl)-butyric acid ethyl ester

Conditions
ConditionsYield
With triethylamine In dimethyl sulfoxide Heating;90%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

5,5'-dimethyl-2,2'-dipyridyl diselenide
496043-96-0

5,5'-dimethyl-2,2'-dipyridyl diselenide

ethyl 2-(5-methyl)pyridylselenobutanoate
1124321-70-5

ethyl 2-(5-methyl)pyridylselenobutanoate

Conditions
ConditionsYield
Stage #1: 5,5'-dimethyl-2,2'-dipyridyl diselenide With sodium tetrahydroborate In ethanol Inert atmosphere;
Stage #2: 4-chloro-butyric acid ethyl ester In ethanol at 10 - 20℃; for 0.25h; Inert atmosphere;
90%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

diphenyl diselenide
1666-13-3

diphenyl diselenide

ethyl 4-(phenylselanyl)butanoate
25059-06-7

ethyl 4-(phenylselanyl)butanoate

Conditions
ConditionsYield
Stage #1: diphenyl diselenide With sodium tetrahydroborate In ethanol for 0.166667h;
Stage #2: 4-chloro-butyric acid ethyl ester In ethanol at 55 - 60℃; for 1.5h;
89%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-(2-phenylethyl)-1H-imidazole
49823-14-5

1-(2-phenylethyl)-1H-imidazole

3-(4-ethoxy-4-oxobutyl)-1-phenethyl-1H-imidazol-3-ium chloride

3-(4-ethoxy-4-oxobutyl)-1-phenethyl-1H-imidazol-3-ium chloride

Conditions
ConditionsYield
In toluene at 80℃; for 0.333333h; Microwave irradiation; Green chemistry;89%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

phthalimide
136918-14-4

phthalimide

ethyl 4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanoate
10294-97-0

ethyl 4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)butanoate

Conditions
ConditionsYield
With caesium carbonate; sodium iodide In N,N-dimethyl-formamide at 70℃; for 0.166667h; Microwave irradiation;88%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

bis(diphenylmethyl) diselenide
24572-14-3

bis(diphenylmethyl) diselenide

ethyl 2-(diphenyl)methylselenobutanoate
1124321-77-2

ethyl 2-(diphenyl)methylselenobutanoate

Conditions
ConditionsYield
Stage #1: bis(diphenylmethyl) diselenide With sodium tetrahydroborate In ethanol Inert atmosphere;
Stage #2: 4-chloro-butyric acid ethyl ester In ethanol at 15 - 20℃; for 0.416667h; Inert atmosphere;
87%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

1-chloro-3-methoxy-benzene
2845-89-8

1-chloro-3-methoxy-benzene

ethyl 4-(3'-methoxyphenyl)butyrate
57816-01-0

ethyl 4-(3'-methoxyphenyl)butyrate

Conditions
ConditionsYield
With nickel(II) bromide dimethoxyethane; pyridine-2,6-bis(N-cyanocarboxamidine); lithium chloride; zinc In 1-methyl-pyrrolidin-2-one at 80℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere;87%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

3-hydroxy-1-isopropyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
371930-42-6

3-hydroxy-1-isopropyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile

ethyl 4-{[4-cyano-1-(propan-2-yl)-5,6,7,8-tetrahydroisoquinolin-3-yl]oxy}butanoate

ethyl 4-{[4-cyano-1-(propan-2-yl)-5,6,7,8-tetrahydroisoquinolin-3-yl]oxy}butanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 75 - 80℃; for 2h;87%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

1-(3-chloropropyl)cyclopropanol
174790-32-0

1-(3-chloropropyl)cyclopropanol

Conditions
ConditionsYield
Stage #1: 4-chloro-butyric acid ethyl ester; ethylmagnesium bromide With titanium(IV) isopropylate In diethyl ether at 20℃; for 0.5h;
Stage #2: With sulfuric acid In diethyl ether
86%
Stage #1: 4-chloro-butyric acid ethyl ester; ethylmagnesium bromide With titanium(IV) isopropylate In diethyl ether at 20℃; Kulinkovich Hydroxycyclopropanation;
Stage #2: With sulfuric acid In diethyl ether
86%
With titanium(IV) isopropylate In diethyl ether Ambient temperature;85%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

2,2'-dipyridyldiselenide
59957-75-4

2,2'-dipyridyldiselenide

ethyl 2-pyridylselenobutanoate
1124321-67-0

ethyl 2-pyridylselenobutanoate

Conditions
ConditionsYield
Stage #1: 2,2'-dipyridyldiselenide With sodium tetrahydroborate In ethanol Inert atmosphere;
Stage #2: 4-chloro-butyric acid ethyl ester In ethanol at 10 - 20℃; for 0.5h; Inert atmosphere;
86%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

bis(2-naphthyl) diselenide
17932-23-9

bis(2-naphthyl) diselenide

ethyl 2-naphthylselenobutanoate
23763-12-4

ethyl 2-naphthylselenobutanoate

Conditions
ConditionsYield
Stage #1: bis(2-naphthyl) diselenide With sodium tetrahydroborate In ethanol Inert atmosphere;
Stage #2: 4-chloro-butyric acid ethyl ester In ethanol at 30 - 35℃; for 1.41667h; Inert atmosphere;
86%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

5-chloro-2-benzoxazolinone
95-25-0

5-chloro-2-benzoxazolinone

ethyl 4-(5-chloro-2(3H)-benzoxazolon-3-yl)butanoate
659724-36-4

ethyl 4-(5-chloro-2(3H)-benzoxazolon-3-yl)butanoate

Conditions
ConditionsYield
Stage #1: 5-chloro-2-benzoxazolinone With sodium ethanolate In ethanol
Stage #2: 4-chloro-butyric acid ethyl ester In N,N-dimethyl-formamide at 80℃; for 8h;
85%
4-chloro-butyric acid ethyl ester
3153-36-4

4-chloro-butyric acid ethyl ester

4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

3-(4-piperidinyl)-1H-indole
17403-09-7

3-(4-piperidinyl)-1H-indole

4-{4-[1-(4-fluoro-benzyl)-1H-indol-3-yl]-piperidin-1-yl}-butyric acid

4-{4-[1-(4-fluoro-benzyl)-1H-indol-3-yl]-piperidin-1-yl}-butyric acid

Conditions
ConditionsYield
85%

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