As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiry4-Phenylbutyric acid Basic information Product Name: 4-Phenylbutyric acid Synonyms: TIMTEC-BB SBB008452;RARECHEM AL BO 0178;PHENYLBUTYRIC-4 ACID;PHENYLBUTYRIC ACID;GAMMA-PHENYL-N-BUTYRIC
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryProduct Name: 4-Phenylbutyric acid Synonyms: TIMTEC-BB SBB008452;RARECHEM AL BO 0178;PHENYLBUTYRIC-4 ACID;PHENYLBUTYRIC ACID;GAMMA-PHENYL-N-BUTYRIC ACID;GAMA-PHENYLBUTYRIC ACID;AKOS BBS-00003749;4-PHENYL-N-
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inquiryPacking: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
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inquiry4-Phenylbutyric acid CAS:1821-12-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter
Cas:1821-12-1
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By
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inquiryHebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all em
Cas:1821-12-1
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:1821-12-1
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inquiryProduct name: 4-Phenylbutyric Acid CAS No.:1821-12-1 Molecule Formula:C10H12O2 Molecule Weight:164.20 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS
Cas:1821-12-1
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inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
(Z)-1-chloro-4-phenylbut-1-en-1-yl acetate
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With lithium hydroxide In tetrahydrofuran; water at 20℃; for 3h; | 100% |
trans-styrylacetic acid
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; hydrogen at 20℃; for 18h; Sealed tube; | 99% |
With formaldehyd; palladium dichloride In sodium hydroxide at 65℃; Hydrogenation; | 98% |
With palladium on activated charcoal; hydrogen In methanol at 20℃; | 78% |
With hydroxylamine; Na3[Fe(CN)5NH3]*3H2O In 1,4-dioxane-d8; water-d2 at 80℃; pH=8; |
Conditions | Yield |
---|---|
With palladium on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr; for 1h; Schlenk technique; | 99% |
With palladium 10% on activated carbon; W(OTf)6; hydrogen at 50℃; under 760.051 Torr; for 12h; | 95% |
With palladium on activated carbon; W(OTf)6; hydrogen In acetic acid at 50℃; under 760.051 Torr; for 12h; | 95% |
With potassium fluoride; palladium diacetate; chlorobenzene In tetrahydrofuran; water at 20℃; for 1h; Inert atmosphere; chemoselective reaction; | 68% |
6-phenylhexane-1,2,3-triol
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With 1‐methyl‐2‐azaadamantane‐N‐oxyl; [bis(acetoxy)iodo]benzene; tetrabutylammomium bromide In water; acetonitrile at 0 - 20℃; for 2h; Inert atmosphere; | 99% |
With 1‐methyl‐2‐azaadamantane‐N‐oxyl; sodium hypochlorite; sodium chlorite In aq. phosphate buffer; acetonitrile at 20℃; for 3h; pH=6.8; Inert atmosphere; | 96% |
Conditions | Yield |
---|---|
With propan-1-ol; bis(1,5-cyclooctadiene)nickel (0); potassium tert-butylate; 4,4-dibenzyl-2-(pyridin-2-yl)-4,5-dihydrooxazole at 60℃; Sealed tube; regioselective reaction; | 99% |
Trifluoro-acetic acid 1-cyano-4-phenyl-1-(pyridin-2-ylsulfanyl)-butyl ester
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With potassium carbonate In water for 2h; | 98% |
With potassium carbonate In acetone at 25℃; for 12h; Yield given; |
2-(3-phenylpropyl)-1,3-dioxolane
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With Oxone; water In tetrahydrofuran at 0 - 20℃; for 12h; Hydrolysis; oxidation; | 98% |
1-(6H-Phenanthridin-5-yl)-4-phenyl-butan-1-one
A
phenanthridine
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With ammonium cerium(IV) nitrate In water; acetonitrile for 0.25h; Product distribution; deprotection; | A n/a B 97% |
Conditions | Yield |
---|---|
enzyme from Synechocystis sp. PCC 6803 In phosphate buffer at 30℃; for 12h; pH=7.2; | 97% |
With potassium phosphate buffer at 30℃; for 24h; Rhodococcus sp. AJ270 cells; | 89.2% |
With dipotassium hydrogenphosphate; phosphoric acid; water; nitrile aminohydrolase E.C. 3.5.5.1 at 25℃; pH=7.50; Thermodynamic data; |
4-phenyl-N-(quinolin-8-yl)butanamide
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol at 130℃; for 16h; | 97% |
Stage #1: 4-phenyl-N-(quinolin-8-yl)butanamide With ozone In dichloromethane at -78℃; Stage #2: With dimethylsulfide Stage #3: With dihydrogen peroxide; lithium hydroxide In tetrahydrofuran; water | 79% |
Conditions | Yield |
---|---|
Stage #1: succinylbenzene With hydrazine hydrate In diethylene glycol at 25℃; for 0.5h; Wolff-Kishner Reduction; Stage #2: With potassium hydroxide In diethylene glycol at 120 - 245℃; for 4.5h; | 95% |
With potassium hydroxide; hydrazine hydrate In diethylene glycol for 0.416667h; Wolff-Kishner reduction; Irradiation; | 90% |
With hydrogenchloride; mercury dichloride; zinc In toluene for 30h; Heating; | 89% |
Conditions | Yield |
---|---|
With air; potassium carbonate In water at 46.84℃; for 24h; | 95% |
Stage #1: 4-phenyl-butan-1-ol With Oxone; sodium ortho-iodobenzenesulfonate In acetonitrile at 70℃; for 1h; Stage #2: With water In acetonitrile for 5h; | 94% |
With potassium peroxymonosulfate; 2-Iodo-5-methylbenzenesulfonic acid In nitromethane at 70℃; for 8h; | 94% |
Conditions | Yield |
---|---|
With ethanol; sodium hydroxide at 50 - 60℃; for 0.666667h; Reagent/catalyst; Green chemistry; Large scale; | 94.4% |
With sodium hydroxide In ethanol at 50 - 60℃; for 0.666667h; Large scale; | 94.4% |
With sodium hydroxide In acetone at 25℃; Kinetics; Thermodynamic data; other temp., ΔH excit., ΔS excit.; |
Conditions | Yield |
---|---|
Stage #1: 4-butanolide; benzene; aluminum (III) chloride In benzene at 50 - 60℃; for 1.5h; Stage #2: With sodium hydroxide In water at 35℃; for 2h; pH=9 - 9.5; Stage #3: With hydrogenchloride In water | 93.7% |
With aluminium trichloride Product distribution; degree of isomerization of the alkyl chain; | 100 % Chromat. |
α-(trichloromethyl)benzenepropanol
4-Phenylbutyric acid
Conditions | Yield |
---|---|
Stage #1: α-(trichloromethyl)benzenepropanol With sodium hydroxide In tert-butyl alcohol at 30℃; for 0.166667h; Stage #2: With sodium tetrahydroborate In tert-butyl alcohol | 93% |
With sodium tetrahydroborate; diphenylselenide; sodium hydroxide In ethanol at 0 - 40℃; Inert atmosphere; | 90% |
2-(3-phenylpropylidene)-1,3-dithiane 1-oxide
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With hydrogenchloride In water; acetonitrile at 55 - 65℃; for 6h; | 91% |
Phosphoric acid 1-cyano-4-phenyl-1-(pyridin-2-ylsulfanyl)-butyl ester dimethyl ester
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With potassium hydroxide | 90% |
Trimethyl-(4-phenyl-butoxy)-silane
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With N-hydroxyphthalimide; oxygen; cobalt(II) benzoate In acetonitrile at 20℃; for 12h; | 90% |
Conditions | Yield |
---|---|
With hydrogenchloride In water; acetic acid at 95 - 110℃; for 20h; Heating / reflux; | 90% |
Multi-step reaction with 2 steps 1: KOH-solution 2: Erhitzen View Scheme | |
Stage #1: ethyl 2-(ethoxycarbonyl)-4-phenylbutanoate With hydrogenchloride; water In acetic acid at 95 - 110℃; for 20h; Stage #2: With sodium hydroxide In water Stage #3: With hydrogenchloride In water pH=1; Product distribution / selectivity; |
Acetic acid 1-cyano-4-phenyl-1-(pyridin-2-ylsulfanyl)-butyl ester
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With potassium carbonate In water | 89% |
With potassium carbonate In acetone at 25℃; for 12h; Yield given; |
1-iodo-butane
2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate
A
1-phenyloctan-4-one
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 5h; | A 87% B 10% |
Phosphoric acid 1-benzenesulfonyl-4-phenyl-1-(pyridin-2-ylsulfanyl)-butyl ester dimethyl ester
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With potassium hydroxide | 87% |
With potassium hydroxide In methanol Yield given; |
tert-butyldimethylsilyl 4-phenylbutyl ether
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With N-hydroxyphthalimide; oxygen; cobalt(II) benzoate In acetonitrile at 20℃; for 15h; | 86% |
1-chloro 4-iodobutane
2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate
A
8-Chloro-1-phenyl-octan-4-one
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 1h; | A 85% B 9% |
4-phenyl-1-iodobutane
2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate
A
1,8-diphenyloctan-4-one
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 5h; | A 85% B 10% |
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With ytterbium(III) triflate In nitromethane for 9h; Ambient temperature; | 85% |
4-iodobutyrophenone
2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate
A
1,8-Diphenyl-octane-1,5-dione
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 5h; | A 84% B 10% |
2-iodooctane
2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate
A
5-methyl-1-phenylundecan-4-one
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 5h; | A 83% B 9% |
7-phenylheptane-2,4-dione
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With ammonium cerium(IV) nitrate In acetonitrile at 20℃; for 4h; | 83% |
4-phenyl-butan-1-ol
A
3-benzyl propionaldehyde
B
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With tert.-butylnitrite; 2-azatricyclo[3.3.1.13,7]dec-2-yloxidanyl; oxygen; magnesium sulfate In acetonitrile at 50℃; for 2h; Reagent/catalyst; chemoselective reaction; | A 83% B 10% |
tryptamine
4-Phenylbutyric acid
N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide
Conditions | Yield |
---|---|
With Trimethyl borate In acetonitrile at 80℃; for 15h; | 100% |
With tris(2,2,2-trifluoroethyl) borate In acetonitrile at 80℃; for 15h; | 70% |
at 180℃; |
Conditions | Yield |
---|---|
With thionyl chloride for 4h; Heating; | 100% |
With sulfuric acid Reflux; | 96% |
With sulfuric acid for 2h; | 93% |
4-Phenylbutyric acid
phenylbutyric acid chloride
Conditions | Yield |
---|---|
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 23℃; | 100% |
With pyridine; thionyl chloride at 20 - 40℃; for 1.5h; | 98% |
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere; Schlenk technique; | 98% |
Conditions | Yield |
---|---|
With tetrachlorosilane; 4-(trifluoromethyl)benzoic anhydride; silver perchlorate In dichloromethane for 24h; Ambient temperature; | 100% |
With tetrachlorosilane; 4-(trifluoromethyl)benzoic anhydride; silver perchlorate In dichloromethane for 24h; Ambient temperature; | 100% |
With trifluorormethanesulfonic acid at 5 - 20℃; for 2h; Cyclization; acylation; | 98% |
rac-methylbenzylamine
4-Phenylbutyric acid
A
N-Octyl-4-phenyl-butyramide
B
N-benzyl-N-methyl-4-phenylbutanamide
C
4-phenyl-N-(1-phenylethyl)butanamide
Conditions | Yield |
---|---|
With potassium hydroxide; bis(o-nitrophenyl)phenylphosphonate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate other amines; multistep reaction; | A 88% B 95% C 100% |
4-Phenylbutyric acid
<γ,γ-D2>Benzolbutansaeure
Conditions | Yield |
---|---|
With hydrogen; water-d2; palladium on activated charcoal at 50℃; for 24h; | 100% |
With palladium 10% on activated carbon; hydrogen; water-d2 at 50℃; under 760.051 Torr; for 12h; | 84% |
With water-d2; sodium carbonate; Raney Co-Al at 90℃; for 2h; | |
With palladium 10% on activated carbon; hydrogen; water-d2 at 50℃; under 760.051 Torr; for 12h; Inert atmosphere; | |
With palladium 10% on activated carbon; hydrogen; water-d2 at 50℃; for 24h; Schlenk technique; |
Conditions | Yield |
---|---|
With [Cl(C6F13C2H4)2SnOSn(C2H4C6F13)2Cl]2 In various solvent(s) at 150℃; for 10h; | 100% |
tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene for 18h; Heating; | 99% |
With Iron(III) isopropoxide; N-butylpyridinium bis(trifluoromethanesulfonyl)imide; zirconium(IV) tetraisopropoxide In n-heptane for 8h; Kinetics; Product distribution; Further Variations:; Reagents; Solvents; Catalysts; Heating; | 99% |
Conditions | Yield |
---|---|
With silica gel-immobilized perchloric acid at 80℃; for 5h; Fischer esterification; Inert atmosphere; Neat (no solvent); | 100% |
tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene for 5h; Heating; | 94% |
With molecualar sevies 4A; tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene at 120℃; for 5h; | 94% |
4-Phenylbutyric acid
4-(cyclohexa-1,4-dien-1-yl)butanoic acid
Conditions | Yield |
---|---|
With ammonia; lithium In tert-butyl alcohol at -78℃; for 5h; Inert atmosphere; | 100% |
With ammonia; lithium; tert-butyl alcohol at -78℃; for 5h; | 100% |
With ethanol; sodium In diethyl ether; ammonia at -78℃; | 86% |
4-Phenylbutyric acid
1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(6-aminoindol-1-yl)-2-butyl]imidazole-4-carboxamide
1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(6-(4-phenylbutyrylamino)indol-1-yl)-2-butyl]imidazole-4-carboxamide
Conditions | Yield |
---|---|
Stage #1: 4-Phenylbutyric acid With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 20℃; for 0.666667h; Stage #2: 1-[(R)-1-(tert-butyldimethylsilyloxy)-4-(6-aminoindol-1-yl)-2-butyl]imidazole-4-carboxamide In dichloromethane at 20℃; for 4h; | 100% |
Conditions | Yield |
---|---|
With dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 3h; | 100% |
With Iron(III) isopropoxide; zirconium(IV) tetraisopropoxide In n-heptane for 15h; | 99% |
dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 3h; Product distribution / selectivity; | 99% |
4-Phenylbutyric acid
(2R,3S,4R,5R)-2-[(E)-3-aminoprop-1-enyl]-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Conditions | Yield |
---|---|
Stage #1: 4-Phenylbutyric acid With dmap; N-ethyl-N,N-diisopropylamine; diisopropyl-carbodiimide In tetrahydrofuran at 20℃; for 24h; Stage #2: With N-ethyl-N,N-diisopropylamine; cyanomethyl bromide In 1-methyl-pyrrolidin-2-one Stage #3: (2R,3S,4R,5R)-2-[(E)-3-aminoprop-1-enyl]-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-3,4-diol In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20℃; | 100% |
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile for 8h; Heating; | 100% |
4-Phenylbutyric acid
4-phenyl-1-[5-(3-piperidin-1-yl-propoxy)-2,3-dihydro-indol-1-yl]-butan-1-one
Conditions | Yield |
---|---|
Stage #1: 5-(3-piperidin-1-yl-propoxy)-2,3-dihydro-1H-indole dihydrochloride; 4-Phenylbutyric acid With N-cyclohexylcarbodiimide-N'-methyl polystyrene HL; benzotriazol-1-ol; triethylamine In chloroform; acetonitrile; tert-butyl alcohol at 20℃; Stage #2: With Silicycle triamine-3 In chloroform; acetonitrile; tert-butyl alcohol for 0.5 - 1h; | 100% |
Conditions | Yield |
---|---|
2-[(N,N-diisopropylamino)methyl]phenylboronic acid In toluene for 20h; Product distribution / selectivity; aza-Baeyer-Villiger Reaction; Heating / reflux; | 100% |
With carbon disulfide; dmap; aluminum oxide In acetonitrile at 200℃; under 37503.8 Torr; for 0.45h; Flow reactor; Green chemistry; | 97% |
methyl (L)-leucinate hydrochloride
4-Phenylbutyric acid
(S)-methyl 4-methyl-2-(4-phenylbutanamido)pentanoate
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 20℃; for 5h; Cooling with ice; | 100% |
Conditions | Yield |
---|---|
With 2,6-dimethylpyridine; dmap; di-tert-butyl dicarbonate In acetonitrile at 20 - 28℃; for 24h; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 25℃; for 2h; | 99.41% |
Conditions | Yield |
---|---|
With 3,4,5-trifluorophenylboronic acid In 1,3,5-trimethyl-benzene for 4h; Heating; | 99% |
With carbon disulfide; dmap; aluminum oxide In acetonitrile at 200℃; under 37503.8 Torr; for 0.45h; Flow reactor; Green chemistry; | 96% |
With boric acid In toluene for 15h; Dean-Stark; Reflux; Green chemistry; chemoselective reaction; | 92% |
Conditions | Yield |
---|---|
With dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 1h; | 99% |
dimesitylammonium pentafluorobenzenesulfonate In n-heptane at 80℃; for 1h; Product distribution / selectivity; | 99% |
iminodibenzyl pentafluorobenzenesulfonate In n-heptane at 115℃; for 1h; Product distribution / selectivity; | 98% |
Conditions | Yield |
---|---|
Stage #1: 4-Phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 60℃; for 0.25h; Stage #2: With iodine In tetrahydrofuran for 5h; Reagent/catalyst; | 99% |
Stage #1: 4-Phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 60℃; for 0.25h; Stage #2: With iodine In tetrahydrofuran for 5h; | 98.4% |
With C25H42N6Rh(1+)*CF3O3S(1-); phenylsilane In tetrahydrofuran at 30℃; for 20h; Inert atmosphere; | 96% |
Conditions | Yield |
---|---|
With 3,4,5-trifluorophenylboronic acid In 1,3,5-trimethyl-benzene for 14.5h; Heating; other solvent; | 99% |
With bis(methylcyclopentadienyl) tin 1.) p-xylene, r.t.; 2.) p-xylene, 9 h, reflux; Yield given. Multistep reaction; |
Conditions | Yield |
---|---|
tetrachlorobis(tetrahydrofuran)hafnium(IV) at 20℃; for 11h; | 99% |
With molecular sevies 4A; tetrachlorobis(tetrahydrofuran)hafnium(IV) at 20℃; for 11h; | 99% |
With sulfuric acid Reflux; | 97% |
3,5-dimethylpiperidine
4-Phenylbutyric acid
Conditions | Yield |
---|---|
With 3,4,5-trifluorophenylboronic acid In toluene for 16h; Heating; other reagents; | 99% |
With 3,5-di-C10F21-C6H3-B(OH)2; 4 A molecular sieve In toluene for 15h; Heating; | 95% |
With boric acid In toluene for 15h; Dean-Stark; Reflux; Green chemistry; chemoselective reaction; | 95% |
With triethoxyantimony In toluene Acylation; Heating; | 44% |
Conditions | Yield |
---|---|
With 3,5-di-C10F21-C6H3-B(OH)2; 4 A molecular sieve In toluene for 4h; Heating; | 99% |
With 4-(dihydroxyboranyl)-1-methylpyridin-1-ium iodide; 1-ethyl-3-methylimidazolium triflate In toluene for 5h; Heating; | 99% |
With boric acid In n-heptane for 15h; Solvent; Dean-Stark; Reflux; Green chemistry; chemoselective reaction; | 99% |
Conditions | Yield |
---|---|
With Iron(III) isopropoxide; zirconium(IV) tetraisopropoxide In n-heptane for 23h; | 99% |
tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene for 24h; Heating; | 94% |
zirconium(IV) oxychloride In n-heptane for 5h; Heating; |
Conditions | Yield |
---|---|
tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene for 24h; Heating; | 99% |
With molecualar sevies 4A; tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene at 120℃; for 24h; | 99% |
Conditions | Yield |
---|---|
tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene for 17h; Heating; | 99% |
With molecular sevies 4A; tetrachlorobis(tetrahydrofuran)hafnium(IV) In toluene at 120℃; for 17h; | 99% |
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