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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-butyne

Cas:107-00-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethyl acetylene

Cas:107-00-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:107-00-6

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:A colorless gas Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Intermediates Transportation:as

1-Butyne

Cas:107-00-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-Butyne

Cas:107-00-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-BUTYNE

Cas:107-00-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-butyne

Cas:107-00-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

1-butyneAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:Used in Synthesis, Pharmaceuticals and other fields Transportation:Sea/air/courier

1-butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory directly supply CAS 107-00-6 with competitive price

Cas:107-00-6

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highl

1-butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#107-00-6;CAT#A851051

Cas:107-00-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl

1-Butyne .

Cas:107-00-6

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Henan Fine Chemicals Co., Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom

1-butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Neway Chemicals Co., Ltd.

best price Appearance:gas

1-butyne

Cas:107-00-6

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemical Solution Industrial

fast delivery, competitive price, good quality, world class quality Storage:Storage in place with condition of being dry and ventilated Package:according to customer's requirement Application:raw material for production Transportation:by express, by

leading factory 1-butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Raymon Biotech Co., Ltd.

1-butyneAppearance:Pls see the Details Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shen

1-butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Skyrun Industrial Co.,Ltd

Price, Purity Application:reagent

CSR081605-62560

Cas:107-00-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

107-00-6

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changzhou Foreign Trade Corp

CFTC?PharmaChem?is?a?service?based?company?in?China,?a?pharmachem?division?of?Changzhou?Foreign?Trade?Corp.,supplying?raw?materials,?intermediates,?APIs?and?fine?chemicals?for?the?pharmaceutical?and?specialty?chemical?industries?worldwide. Applicatio

but-1-yne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Sigma-Aldrich Chemie GmbH

Package:100 g in Sure-Pac(TM)

1-Butyne

Cas:107-00-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

2-cyclohexylacetylene
931-48-6

2-cyclohexylacetylene

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl-3-cyclohexylprop-2-yn-1-amine

N-benzyl-3-cyclohexylprop-2-yn-1-amine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 97%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

4-methylpentyne
7154-75-8

4-methylpentyne

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl-5-methylhex-2-yn-1-amine

N-benzyl-5-methylhex-2-yn-1-amine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 95%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

2,2-dimethyl-3-butyne
917-92-0

2,2-dimethyl-3-butyne

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl 4,4-dimethyl-pent-2-ynylamine
1610010-33-7

N-benzyl 4,4-dimethyl-pent-2-ynylamine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 95%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

hex-1-yne
693-02-7

hex-1-yne

A

but-1-yne
107-00-6

but-1-yne

B

N-benzylhept-2-yn-1-amine
1379038-80-8

N-benzylhept-2-yn-1-amine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 87%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

4-Phenyl-1-butyne
16520-62-0

4-Phenyl-1-butyne

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl-5-phenylpent-2-yn-1-amine

N-benzyl-5-phenylpent-2-yn-1-amine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 87%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

Cyclopropylacetylene
6746-94-7

Cyclopropylacetylene

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl 3-cyclopropyl-prop-2-ynylamine

N-benzyl 3-cyclopropyl-prop-2-ynylamine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 80%
triphenylphosphoranylidene-2-butanone
19753-66-3

triphenylphosphoranylidene-2-butanone

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
at 750℃; under 0.01 Torr;78%
at 750℃;78%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

phenylacetylene
536-74-3

phenylacetylene

A

but-1-yne
107-00-6

but-1-yne

B

N-(3-phenylprop-2-ynyl)benzenemethanamine
40032-57-3

N-(3-phenylprop-2-ynyl)benzenemethanamine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 75%
N-benzyl-N-pent-2-ynylamine

N-benzyl-N-pent-2-ynylamine

1-ethynyl-4-fluorobenzene
766-98-3

1-ethynyl-4-fluorobenzene

A

but-1-yne
107-00-6

but-1-yne

B

N-benzyl-3-(4-fluorophenyl)prop-2-yn-1-amine

N-benzyl-3-(4-fluorophenyl)prop-2-yn-1-amine

Conditions
ConditionsYield
With Lu(N(SiMe3)2)3 In toluene at 130℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;A n/a
B 70%
2-propynyl chloride
624-65-7

2-propynyl chloride

dimethyldiazene

dimethyldiazene

A

but-1-yne
107-00-6

but-1-yne

B

2,3-dimethylbutene
590-19-2

2,3-dimethylbutene

Conditions
ConditionsYield
at 20℃; under 50 Torr; Kinetics; radical cross-combination reaction; Photolysis;A 60%
B 40%
crushed scrap tires

crushed scrap tires

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
at 750℃; Formation of xenobiotics;0.012%
3-buten-1-yne
689-97-4

3-buten-1-yne

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With nickel Hydrogenation;
1-butylene
106-98-9

1-butylene

butene-2
107-01-7

butene-2

A

but-1-yne
107-00-6

but-1-yne

B

dimethylacetylene
503-17-3

dimethylacetylene

ethyl bromide
74-96-4

ethyl bromide

sodium acetylide
1066-26-8

sodium acetylide

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With ammonia
diethyl sulfate
64-67-5

diethyl sulfate

sodium acetylide
1066-26-8

sodium acetylide

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With ammonia
With diphenylether at 130 - 190℃;
With xylene
With tetrahydrofuran; N,N-dimethyl-formamide; benzene at 0℃;
In 5,5-dimethyl-1,3-cyclohexadiene at 90℃;
dimethylacetylene
503-17-3

dimethylacetylene

cefaloridine
50-59-9

cefaloridine

A

but-1-yne
107-00-6

but-1-yne

B

2,3-dimethylbutene
590-19-2

2,3-dimethylbutene

Conditions
ConditionsYield
at 280℃;
dimethylacetylene
503-17-3

dimethylacetylene

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With sodium Zers. der gebildeten Natrium-Verbindung mit Wasser;
2-bromobutene
23074-36-4

2-bromobutene

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With potassium carbonate at 100℃;
With potassium hydroxide at 120 - 125℃;
4-methoxy-but-2-yne
2768-41-4

4-methoxy-but-2-yne

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With sodium amide
2,3-dibromobutane
5408-86-6

2,3-dibromobutane

A

but-1-yne
107-00-6

but-1-yne

B

dimethylacetylene
503-17-3

dimethylacetylene

Conditions
ConditionsYield
With potassium hydroxide; diethylene glycol at 180℃;
(E)/(Z)-1-bromo-1-butene
31844-98-1

(E)/(Z)-1-bromo-1-butene

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With potassium hydroxide; ethanol at 180℃;
2,3-dimethylbutene
590-19-2

2,3-dimethylbutene

cefaloridine
50-59-9

cefaloridine

A

but-1-yne
107-00-6

but-1-yne

B

buta-1,3-diene
106-99-0

buta-1,3-diene

Conditions
ConditionsYield
at 330℃;
2,3-dimethylbutene
590-19-2

2,3-dimethylbutene

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With diethyl ether; sodium Zers. der gebildeten Natrium-Verbindung mit Wasser;
2,3-dimethylbutene
590-19-2

2,3-dimethylbutene

A

but-1-yne
107-00-6

but-1-yne

B

butene-2
107-01-7

butene-2

Conditions
ConditionsYield
With sodium at 60℃;
2,2-dichlorobutane
4279-22-5

2,2-dichlorobutane

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With potassium hydroxide at 130 - 135℃; unter Druck, Erwaermen des Destillates mit Natrium unter Druck auf 100grad;
With vaseline oil; sodium amide at 170 - 219℃;
but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With potassium hydroxide at 130 - 135℃; unter Druck, Erwaermen des Destillates mit Natrium unter Druck auf 100grad;
N-(2-hydroxy-butyl)-N-nitroso-benzamide
99841-48-2

N-(2-hydroxy-butyl)-N-nitroso-benzamide

but-1-yne
107-00-6

but-1-yne

sodium acetylide
1066-26-8

sodium acetylide

ethyl iodide
75-03-6

ethyl iodide

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With ammonia at -40℃;
butanone
78-93-3

butanone

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With phosphorus pentachloride; potassium carbonate
acetylene
74-86-2

acetylene

but-1-yne
107-00-6

but-1-yne

Conditions
ConditionsYield
With iron sulfide at 300 - 310℃;
but-1-yne
107-00-6

but-1-yne

methyloxirane
75-56-9, 16033-71-9

methyloxirane

(R,S)-4-Heptyn-2-ol
19781-81-8

(R,S)-4-Heptyn-2-ol

Conditions
ConditionsYield
With n-butyllithium In N,N,N,N,N,N-hexamethylphosphoric triamide 1.)-20 deg C, 30 min., 2.)R.T.;100%
46%
but-1-yne
107-00-6

but-1-yne

triphenylstannane
892-20-6

triphenylstannane

crotyltriphenylstannane
41391-52-0, 466696-60-6, 63787-69-9

crotyltriphenylstannane

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile) In tetrahydrofuran 70°C, 3 h, 5:1;;100%
With azobisisobutyronitrile In tetrahydrofuran 70°C, 3 h, 5:1;;100%
With azo-bis-isobutyric acid dinitrile In tetrahydrofuran reaction for 3 h at 70°C in presence of azoisobutyric acid dinitrile;;
but-1-yne
107-00-6

but-1-yne

5-fluoro-2-iodoaniline

5-fluoro-2-iodoaniline

2-but-1-ynyl-5-fluoro-phenylamine
1158918-72-9

2-but-1-ynyl-5-fluoro-phenylamine

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at 20℃; for 3h; Inert atmosphere;100%
but-1-yne
107-00-6

but-1-yne

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2-[(1E)-but-1-en-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1301680-12-5

2-[(1E)-but-1-en-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
With zirconocene dichloride; lithium triethylborohydride; triethylamine In tetrahydrofuran at -78 - 20℃; Inert atmosphere;100%
Stage #1: but-1-yne; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: With bis(pentamethylcyclopentadienyl)zirconium(IV) dichloride; lithium triethylborohydride; triethylamine In tetrahydrofuran at -78 - 20℃; for 20h;
65%
With bis(cyclohexanyl)borane In neat (no solvent) at -78 - 0℃; for 6h; Glovebox; Inert atmosphere; enantioselective reaction;
but-1-yne
107-00-6

but-1-yne

N-(1-ethylpropyl)-2-iodo-4-nitroaniline
150057-74-2

N-(1-ethylpropyl)-2-iodo-4-nitroaniline

(2-But-1-ynyl-4-nitro-phenyl)-(1-ethyl-propyl)-amine
150057-82-2

(2-But-1-ynyl-4-nitro-phenyl)-(1-ethyl-propyl)-amine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide for 20h; Ambient temperature;99%
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

but-1-yne
107-00-6

but-1-yne

pent-2-yn-1-ol
6261-22-9

pent-2-yn-1-ol

Conditions
ConditionsYield
With paraformaldehyde In tetrahydrofuran; hexane99%
but-1-yne
107-00-6

but-1-yne

(S)-2-[(4-methoxybenzyloxy)methyl]oxirane
80910-01-6, 108836-41-5, 134733-19-0, 144069-33-0

(S)-2-[(4-methoxybenzyloxy)methyl]oxirane

(S)-1-(4-methoxybenzyloxy)hept-4-yn-2-ol
1099777-06-6

(S)-1-(4-methoxybenzyloxy)hept-4-yn-2-ol

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1.5h; Inert atmosphere;
Stage #2: (S)-2-[(4-methoxybenzyloxy)methyl]oxirane With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;
99%
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78 - -30℃; for 0.5h; Inert atmosphere;
Stage #2: With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -30℃; for 0.166667h; Inert atmosphere;
Stage #3: (S)-2-[(4-methoxybenzyloxy)methyl]oxirane In tetrahydrofuran; hexane at -78℃; for 2h; Inert atmosphere; regioselective reaction;
95%
but-1-yne
107-00-6

but-1-yne

methyl 6-bromo-5-fluoropyridine-2-carboxylate
1210419-26-3

methyl 6-bromo-5-fluoropyridine-2-carboxylate

methyl 6-but-1-yn-1-yl-5-fluoropyridine-2-carboxylate

methyl 6-but-1-yn-1-yl-5-fluoropyridine-2-carboxylate

Conditions
ConditionsYield
Stage #1: methyl 6-bromo-5-fluoropyridine-2-carboxylate With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In 1,4-dioxane at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: but-1-yne In 1,4-dioxane at 60℃; for 3h; Sonogashira Cross-Coupling;
99%
but-1-yne
107-00-6

but-1-yne

2,3-dimethyl-2,3-butane diol
76-09-5

2,3-dimethyl-2,3-butane diol

(Z)-2-(2-bromobut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

(Z)-2-(2-bromobut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
Stage #1: but-1-yne With Bromoform In dichloromethane at -78 - 20℃; Inert atmosphere; Schlenk technique;
Stage #2: 2,3-dimethyl-2,3-butane diol In dichloromethane at -78 - 20℃; Inert atmosphere; Schlenk technique;
99%
but-1-yne
107-00-6

but-1-yne

sec-Butyl-(2-iodo-4-nitro-phenyl)-amine
174275-08-2

sec-Butyl-(2-iodo-4-nitro-phenyl)-amine

sec-Butyl-(2-but-1-ynyl-4-nitro-phenyl)-amine
174275-10-6

sec-Butyl-(2-but-1-ynyl-4-nitro-phenyl)-amine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In N,N-dimethyl-formamide for 20h; Ambient temperature;98%
but-1-yne
107-00-6

but-1-yne

N-benzyl-6-chloro-5-iodo-2-(methylthio)-pyrimidin-4-amine
1034619-80-1

N-benzyl-6-chloro-5-iodo-2-(methylthio)-pyrimidin-4-amine

N-benzyl-5-(but-1-ynyl)-6-chloro-2-(methylthio)-pyrimidin-4-amine
1034619-81-2

N-benzyl-5-(but-1-ynyl)-6-chloro-2-(methylthio)-pyrimidin-4-amine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 55℃; for 1.5h; Sonogashira coupling; Inert atmosphere;98%
but-1-yne
107-00-6

but-1-yne

4β-azido-4-deoxy-4′-demethylepipodophyllotoxin
117604-05-4

4β-azido-4-deoxy-4′-demethylepipodophyllotoxin

4'-O-demethyl-4β-[4-(ethyl)-1,2,3-triazol-1-yl]-4-desoxypodophyllotoxin
1310548-37-8

4'-O-demethyl-4β-[4-(ethyl)-1,2,3-triazol-1-yl]-4-desoxypodophyllotoxin

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; L-ascorbic acid sodium salt In water; tert-butyl alcohol at 0 - 20℃;98%
4-toluenesulfonyl azide
941-55-9

4-toluenesulfonyl azide

but-1-yne
107-00-6

but-1-yne

C11H13N3O2S

C11H13N3O2S

Conditions
ConditionsYield
In toluene at 0℃; for 6h; Inert atmosphere;98%
With copper(I) thiophene-2-carboxylate In 1,2-dichloro-ethane at 20℃; for 6h; Glovebox;
but-1-yne
107-00-6

but-1-yne

methyl chloroformate
79-22-1

methyl chloroformate

methyl pent-2-ynoate
24342-04-9

methyl pent-2-ynoate

Conditions
ConditionsYield
With n-butyllithium In diethyl ether 1.) -80 deg C, 30 min, 2.) warm to room temperature;97%
Stage #1: but-1-yne With n-butyllithium
Stage #2: methyl chloroformate
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: methyl chloroformate In tetrahydrofuran at -78℃; for 3h; Inert atmosphere;
but-1-yne
107-00-6

but-1-yne

N-methoxy-N-methyl-hex-5-enamide
122334-35-4

N-methoxy-N-methyl-hex-5-enamide

dec-9-en-3-yn-5-one
1244781-31-4

dec-9-en-3-yn-5-one

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78 - 0℃;
Stage #2: N-methoxy-N-methyl-hex-5-enamide In tetrahydrofuran; hexane at -78 - -10℃;
97%
but-1-yne
107-00-6

but-1-yne

(S)-Propylene oxide
16088-62-3

(S)-Propylene oxide

(S)-(+)-hept-4-yn-2-ol
90192-96-4

(S)-(+)-hept-4-yn-2-ol

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -50 - 0℃; for 0.5h; Inert atmosphere;
Stage #2: (S)-Propylene oxide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -20 - 20℃; for 16.5h;
96%
With n-butyllithium In N,N,N,N,N,N-hexamethylphosphoric triamide 1.)-20 deg C, 30 min., 2.)R.T.;87%
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium 1) THF, -40 to 0 deg C, 2) -20 to 0 deg C; Yield given. Multistep reaction;
With n-butyllithium In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide at -50 - 0℃; for 16h; Inert atmosphere;
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In tetrahydrofuran at -78 - 20℃; for 16h; Inert atmosphere;
but-1-yne
107-00-6

but-1-yne

phenyldimethylsilyl chloride
768-33-2

phenyldimethylsilyl chloride

1-dimethyl(phenyl)silylbut-1-yne
146758-90-9

1-dimethyl(phenyl)silylbut-1-yne

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane 1.) -45 deg C, 1 h, 2.) -45 to 20 deg C, 1 h;96%
With n-butyllithium 1.) hexane, THF, 0 deg C, 30 min, 2.) reflux, 18 h; Yield given. Multistep reaction;
but-1-yne
107-00-6

but-1-yne

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

4-but-1-ynyl-benzaldehyde
652974-14-6

4-but-1-ynyl-benzaldehyde

Conditions
ConditionsYield
With copper(l) iodide; tris(dibenzylideneacetone)dipalladium (0); triphenylphosphine; triethylamine at 80℃; for 24h; Sonogashira cross-coupling reaction;96%
but-1-yne
107-00-6

but-1-yne

2-(1H-pyrrol-1-yl)aniline
6025-60-1

2-(1H-pyrrol-1-yl)aniline

4-ethyl-4-methyl-4,5-dihydro-pyrrolo[1,2-a]quinoxaline

4-ethyl-4-methyl-4,5-dihydro-pyrrolo[1,2-a]quinoxaline

Conditions
ConditionsYield
With tetrafluoroboric acid diethyl ether; dodecacarbonyl-triangulo-triruthenium In benzene at 95℃; for 24h;96%
but-1-yne
107-00-6

but-1-yne

4β-azido-4-deoxypodophyllotoxin
155252-34-9

4β-azido-4-deoxypodophyllotoxin

4β-[4-(ethyl)-1,2,3-triazol-1-yl]-4-desoxypodophyllotoxin
1310548-29-8

4β-[4-(ethyl)-1,2,3-triazol-1-yl]-4-desoxypodophyllotoxin

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; L-ascorbic acid sodium salt In water; tert-butyl alcohol at 0 - 20℃;96%
but-1-yne
107-00-6

but-1-yne

2-bromo-5-((tert-butyldimethylsilyl)oxy)cyclopent-1-ene-1-carbaldehyde

2-bromo-5-((tert-butyldimethylsilyl)oxy)cyclopent-1-ene-1-carbaldehyde

1-(2-bromo-5-((tert-butyldimethylsilyl)oxy)-cyclopent-1-en-1-yl)pent-2-yn-1-ol

1-(2-bromo-5-((tert-butyldimethylsilyl)oxy)-cyclopent-1-en-1-yl)pent-2-yn-1-ol

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78 - -30℃; for 0.5h; Inert atmosphere;
Stage #2: 2-bromo-5-((tert-butyldimethylsilyl)oxy)cyclopent-1-ene-1-carbaldehyde In tetrahydrofuran; hexane at -78℃; for 2h; Inert atmosphere;
96%
but-1-yne
107-00-6

but-1-yne

(R)-propylene oxide
15448-47-2

(R)-propylene oxide

(R)-(-)-Heptyn-2-ol
90192-97-5

(R)-(-)-Heptyn-2-ol

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78 - 0℃; for 1h;
Stage #2: (R)-propylene oxide With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran; hexane at -20 - 20℃; for 17h;
95%
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In tetrahydrofuran at -78 - 20℃; for 12h;95%
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: (R)-propylene oxide With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone In tetrahydrofuran; hexane at -30 - 20℃; for 18h; Inert atmosphere;
85%
With n-butyllithium In N,N,N,N,N,N-hexamethylphosphoric triamide 1.)-20 deg C, 30 min., 2.)R.T.;81%
With n-butyllithium In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide at -50 - 0℃; for 16h; Inert atmosphere;
but-1-yne
107-00-6

but-1-yne

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

2-methyl-2-(1-methylenepropyl)malonic acid diethyl ester

2-methyl-2-(1-methylenepropyl)malonic acid diethyl ester

Conditions
ConditionsYield
With In(OSO2CF3)3 at 110℃;95%
but-1-yne
107-00-6

but-1-yne

12-bromo-1-(2-tetrahydropyranyloxy)-(Z)-11-dodecene
127022-43-9

12-bromo-1-(2-tetrahydropyranyloxy)-(Z)-11-dodecene

A

octa-3,5-diyne
16387-70-5

octa-3,5-diyne

B

2-[((Z)-Hexadec-11-en-13-ynyl)oxy]-tetrahydro-pyran
127022-44-0

2-[((Z)-Hexadec-11-en-13-ynyl)oxy]-tetrahydro-pyran

Conditions
ConditionsYield
With propylamine; copper(l) iodide; diisobutylaluminium hydride; bis-triphenylphosphine-palladium(II) chloride In toluene 1.) room temperature, 12 h, 2.) 50 deg C, 4 h;A n/a
B 94%
but-1-yne
107-00-6

but-1-yne

paraformaldehyde-d2
1664-98-8

paraformaldehyde-d2

<1,1-2H2>pent-2-yn-1-ol
115150-62-4

<1,1-2H2>pent-2-yn-1-ol

Conditions
ConditionsYield
Stage #1: but-1-yne With ethyl bromide; magnesium In tetrahydrofuran at -5 - 30℃; Inert atmosphere;
Stage #2: paraformaldehyde-d2 In tetrahydrofuran for 3h; Reflux;
Stage #3: With sulfuric acid In tetrahydrofuran; water Cooling with ice;
94%
Stage #1: but-1-yne With ethylmagnesium bromide In tetrahydrofuran at -5 - 30℃; for 1.25h;
Stage #2: paraformaldehyde-d2 In tetrahydrofuran for 3h; Reflux;
but-1-yne
107-00-6

but-1-yne

tert-butyldimethylsilyl (S)-glycidyl ether
78906-15-7, 114413-26-2, 124150-87-4, 123237-62-7

tert-butyldimethylsilyl (S)-glycidyl ether

C13H26O2Si
1365694-18-3

C13H26O2Si

Conditions
ConditionsYield
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran at -78℃; for 0.25h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl (S)-glycidyl ether With boron trifluoride diethyl etherate In tetrahydrofuran at -78℃; for 3h; Inert atmosphere;
94%
Stage #1: but-1-yne With n-butyllithium In tetrahydrofuran at -78℃; for 0.25h;
Stage #2: tert-butyldimethylsilyl (S)-glycidyl ether With boron trifluoride diethyl etherate In tetrahydrofuran at -78℃; for 3h;
94%
With n-butyllithium; boron trifluoride diethyl etherate In tetrahydrofuran at -78℃;84%
but-1-yne
107-00-6

but-1-yne

4,4-diethyl-1,2-dithiolane
41174-10-1

4,4-diethyl-1,2-dithiolane

2,6,6-Triethyl-6,7-dihydro-5H-[1,4]dithiepine

2,6,6-Triethyl-6,7-dihydro-5H-[1,4]dithiepine

Conditions
ConditionsYield
With potassium tert-butylate In tert-butyl alcohol under 760 Torr; for 48h; Ambient temperature;93%

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