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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (S)-Methyl Oxazaborolidine supplier in China

Cas:112022-81-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

(S)-2-methyl-CBS-oxazaborolidine

Cas:112022-81-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (S)-Methyl Oxazaborolidine

Cas:112022-81-8

Min.Order:1

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

(S)-2-Methyl-CBS-oxazaborolidine

Cas:112022-81-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(S)-Methyl oxazaborolidine

Cas:112022-81-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole / LIDE PHARMA- Factory supply / Best price

Cas:112022-81-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Competitve Price in stock CAS 112022-81-8 with competitive price

Cas:112022-81-8

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Hangzhou Maytime Bio-Tech Co.,Ltd.

Top supplier for S-2-meyl-CBS-oxazaborolidine CAS:112022-81-8 with high quality and competitive price. Appearance:white to off-white solid Storage:store in well closed container Package:25kgs/fiber drum Application:used as pharmaceutical intermed

S-2-meyl-CBS-oxazaborolidine CAS:112022-81-8

Cas:112022-81-8

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole,tetrahydro-1-methyl-3,3-diphenyl-, (3aS)- 112022-81-8

Cas:112022-81-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole CAS: 112022-81-8 MF: C18H20BNO MW: 277.17 EINECS: 601-150-5 Mol File: 112022-81-8.mol (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Struct

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Organic Synthesis, (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole CAS:112022-81-8

Cas:112022-81-8

Min.Order:1 Kilogram

FOB Price: $136.0 / 142.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole,tetrahydro-1-methyl-3,3-diphenyl-, (3aS)-

Cas:112022-81-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole,tetrahydro-1-methyl-3,3-diphenyl-, (3aS)-

Cas:112022-81-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

(S)-5,5-Diphenyl-2-Methyl-3,4-Propano-1,3,2-Oxazaborolidine

Cas:112022-81-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

(S)-2-methyl-CBS-oxazaborolidine(solid)

Cas:112022-81-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(S)-METHYL OXAZABOROLIDINE

Cas:112022-81-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(S)-3,3-Diphenyl-1-methylpyrrolidino[1.2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(S)-2-Methyl-CBS-oxazaborolidine

Cas:112022-81-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

(S)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Cas:112022-81-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality (S)-Methyl Oxazaborolidine

Cas:112022-81-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

99% purity of (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole/(S)-2-methyl-CBS-oxazaborolidine CAS NO.112022-81-8

Cas:112022-81-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white or cream white solid Storage:In Room Temperature Package:1kg/bag,or as your request Application:For medicine , pesticide intermediates Transportation: as your request Port:

(S)-2-Methyl-CBS-oxazaborolidine

Cas:112022-81-8

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(S)-2-Methyl-CBS-oxazaborolidine

Cas:112022-81-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Cas:112022-81-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methylbis(diisopropylamino)borane
151293-60-6

methylbis(diisopropylamino)borane

(R)-α,α-diphenylprolinol
22348-32-9

(R)-α,α-diphenylprolinol

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In tetrahydrofuran; toluene reflux for 30 min; solvents are removed;89%
methylboronic acid

methylboronic acid

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In toluene byproducts: H2O; refluxing of pyrrolidine deriv. and methylboronic acid in toluene for 3 h; evapn. of solvent in vac.;86%
With 4 A molecular sieve In toluene byproducts: H2O; react. of pyrrolidine deriv. and methylboronic acid in toluene at 23°C in presence of molecular sieves within 1,5 h; evapn. of solvent in vac.;86%
dihydroxy-methyl-borane
13061-96-6

dihydroxy-methyl-borane

(R)-α,α-diphenylprolinol
22348-32-9

(R)-α,α-diphenylprolinol

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In n-heptane at 40℃; Solvent; Temperature; Inert atmosphere; Reflux; Large scale;83%
dihydroxy-methyl-borane
13061-96-6

dihydroxy-methyl-borane

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In toluene for 3h; Heating;
With 4 A molecular sieve In toluene for 15h; Heating;
In toluene for 14h; Cyclization; Heating;
Trimethylboroxine
823-96-1

Trimethylboroxine

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In toluene at 20℃; for 0.6h;
In toluene
In toluene at 20 - 155℃;
C22H30BNO2

C22H30BNO2

methyldi-n-butoxyborane
86595-28-0

methyldi-n-butoxyborane

A

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

B

butan-1-ol
71-36-3

butan-1-ol

Conditions
ConditionsYield
In toluene for 4h; Heating / reflux;
6-phenylsulfanyl-3,4-dihydro-2H-naphthalen-1-one
149915-80-0

6-phenylsulfanyl-3,4-dihydro-2H-naphthalen-1-one

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(R)-6-phenylsulfanyl-1,2,3,4-tetrahydro-naphthalen-1-ol
895534-20-0

(R)-6-phenylsulfanyl-1,2,3,4-tetrahydro-naphthalen-1-ol

Conditions
ConditionsYield
Stage #1: 6-phenylsulfanyl-3,4-dihydro-2H-naphthalen-1-one; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole With borane N,N-diethylaniline complex In toluene at 30 - 32℃; for 3h;
Stage #2: With hydrogenchloride; methanol; water In toluene for 0.666667h;
98%
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

2,2,2-trifluoro-1-(1,1'-biphenyl-2-yl)ethanone
302912-29-4

2,2,2-trifluoro-1-(1,1'-biphenyl-2-yl)ethanone

1-([1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethan-1-ol
945978-45-0

1-([1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethan-1-ol

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; toluene96%
With hydrogenchloride In tetrahydrofuran; toluene96%
dimethyl sulfide borane
13292-87-0

dimethyl sulfide borane

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(3aS)-1-methyl-3, 3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole borane complex

(3aS)-1-methyl-3, 3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole borane complex

Conditions
ConditionsYield
In toluene vac. transferring of toluene onto (S)-2-methyl-CBS-oxazaborolidine; addn. of BH3*SMe2 by syringe at -78°C; stirring at room temp. for 2 hand then at -10°C for 5 h; vac. transferring of pentane; pptn., filtration, washing with pentane; removal of volatiles in vac., drying overnight;91%
BH3.S(CH3)2

BH3.S(CH3)2

(S)-oxazaborolidine

(S)-oxazaborolidine

diethyl ether
60-29-7

diethyl ether

2-pentyl-2-cyclopenten-1-one
25564-22-1

2-pentyl-2-cyclopenten-1-one

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

A

(+)-(1R)-2-pentyl-1-cyclopenten-1-ol

(+)-(1R)-2-pentyl-1-cyclopenten-1-ol

B

(R)-2-pentyl-2-cyclopentenol
202530-97-0

(R)-2-pentyl-2-cyclopentenol

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; methanol; tolueneA n/a
B 89%
Sn(C4H9)3(CH3)2C3HO
160539-64-0

Sn(C4H9)3(CH3)2C3HO

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Sn(C4H9)3(CH3)2C3H2(OH)

Sn(C4H9)3(CH3)2C3H2(OH)

Conditions
ConditionsYield
With benzo[1,3,2]dioxaborole In toluene -30°C to -20°C;85%
C20H16O7

C20H16O7

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

C20H18O7

C20H18O7

Conditions
ConditionsYield
Stage #1: (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole With dimethylsulfide borane complex In tetrahydrofuran; toluene at 0℃; for 0.25h;
Stage #2: C20H16O7 In tetrahydrofuran at -78 - 20℃; for 1h; stereoselective reaction;
85%
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
With water77%
3-Nitroacetophenone
121-89-1

3-Nitroacetophenone

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(R)-1-(3-nitrophenyl)ethanol
76116-24-0

(R)-1-(3-nitrophenyl)ethanol

Conditions
ConditionsYield
Stage #1: (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole With borane Ν,Ν-diethylaniline complex In toluene at 30℃; for 0.333333h; Inert atmosphere;
Stage #2: 3-Nitroacetophenone In toluene at 30℃; for 5.5h;
74%
1-(3-Bromophenyl)ethanone
2142-63-4

1-(3-Bromophenyl)ethanone

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
With dimethyl sulfide borane In tetrahydrofuran; toluene at 30℃; for 7h;54%
borane-THF

borane-THF

3-(2-bromoacetyl)pyridine hydrobromide
17694-68-7

3-(2-bromoacetyl)pyridine hydrobromide

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(1R)-2-bromo-1-(3-pyridinyl)-1-ethanol
391906-07-3

(1R)-2-bromo-1-(3-pyridinyl)-1-ethanol

Conditions
ConditionsYield
In tetrahydrofuran; methanol34%
In tetrahydrofuran; methanol27%
2-Chloro-4'-fluoroacetophenone
456-04-2

2-Chloro-4'-fluoroacetophenone

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran
aqueous potassium carbonate

aqueous potassium carbonate

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

[3-Hydroxy-3-(3-pyridinyl)propyl]carbamic acid, 1,1-dimethylethyl ester
357405-01-7

[3-Hydroxy-3-(3-pyridinyl)propyl]carbamic acid, 1,1-dimethylethyl ester

Conditions
ConditionsYield
With hydrogenchloride; borane In tetrahydrofuran; methanol; toluene928 mg (73%)
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

4-chloro-1-(4-methylphenyl)butan-1-one
38425-26-2

4-chloro-1-(4-methylphenyl)butan-1-one

R-α-(3-Chloropropyl)-4-methyl-benzenemethanol
357443-51-7

R-α-(3-Chloropropyl)-4-methyl-benzenemethanol

Conditions
ConditionsYield
In tetrahydrofuran; methanol
{1-[4-(6-Methoxy-pyridin-3-yl)-2-oxo-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

{1-[4-(6-Methoxy-pyridin-3-yl)-2-oxo-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

dimethyl sulfide borane
13292-87-0

dimethyl sulfide borane

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

{1-[2(R)-Hydroxy-4-(6-methoxy-pyridin-3-yl)-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl }-carbamic Acid Tert-butyl Ester

{1-[2(R)-Hydroxy-4-(6-methoxy-pyridin-3-yl)-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl }-carbamic Acid Tert-butyl Ester

Conditions
ConditionsYield
In tetrahydrofuran; methanol; dichloromethane; toluene
{1-[4-(2-methyl-pyrimidin-5-yl)-2-oxo-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

{1-[4-(2-methyl-pyrimidin-5-yl)-2-oxo-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

dimethyl sulfide borane
13292-87-0

dimethyl sulfide borane

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

{1-[2-Hydroxy-4-(2-methyl-pyrimidin-5-yl)-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

{1-[2-Hydroxy-4-(2-methyl-pyrimidin-5-yl)-but-3-enyl]-5(R)-methyl-2-oxo-pyrrolidin-3(S)-yl}-carbamic Acid Tert-butyl Ester

Conditions
ConditionsYield
In tetrahydrofuran; methanol; dichloromethane; toluene
borane-THF

borane-THF

2,4-dichlorophenacyl bromide
2631-72-3

2,4-dichlorophenacyl bromide

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(S)-2-bromo-1-(2,4-dichlorophenyl)ethan-1-ol
187164-20-1

(S)-2-bromo-1-(2,4-dichlorophenyl)ethan-1-ol

Conditions
ConditionsYield
In tetrahydrofuran; methanol
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

5-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepine-4,8-dione
191591-86-3

5-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepine-4,8-dione

(+)-5-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-8-hydroxy-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepin-4-one

(+)-5-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-8-hydroxy-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepin-4-one

Conditions
ConditionsYield
In toluene
(E)-(phenylsulfinyl)but-3-en-2-one
33944-98-8

(E)-(phenylsulfinyl)but-3-en-2-one

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(R,E)-4-phenylthio-3-buten-2-ol

(R,E)-4-phenylthio-3-buten-2-ol

2,2,2-trifluoro-1-(4-fluorophenyl)ethanone
655-32-3

2,2,2-trifluoro-1-(4-fluorophenyl)ethanone

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

2,2,2-trifluoro-1-(4-fluorophenyl)ethanol
17556-41-1, 50562-19-1, 131832-02-5

2,2,2-trifluoro-1-(4-fluorophenyl)ethanol

Conditions
ConditionsYield
With benzo[1,3,2]dioxaborole In dichloromethane at -78℃;n/a
borane
13283-31-3

borane

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Conditions
ConditionsYield
In tetrahydrofuran react. of oxazaborolidine deriv. and BH3 in soln.; not isolated;
isopropyl 7-{(4R)-4-[(1E)-4,4-difluoro-3-oxo-4-phenylbut-1-en-1-yl]-2-oxo-1,3-oxazinan-3-yl}heptanoate
768400-09-5

isopropyl 7-{(4R)-4-[(1E)-4,4-difluoro-3-oxo-4-phenylbut-1-en-1-yl]-2-oxo-1,3-oxazinan-3-yl}heptanoate

isopropyl 7-[(4R)-4-formyl-2-oxo-1,3-oxazinan-3-yl]heptanoate
768400-08-4

isopropyl 7-[(4R)-4-formyl-2-oxo-1,3-oxazinan-3-yl]heptanoate

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

isopropyl 7-{(4R)-4-[(1E)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-yl]-2-oxo-1,3-oxanzinan-3-yl}heptanoate

isopropyl 7-{(4R)-4-[(1E)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-yl]-2-oxo-1,3-oxanzinan-3-yl}heptanoate

Conditions
ConditionsYield
Stage #1: isopropyl 7-{(4R)-4-[(1E)-4,4-difluoro-3-oxo-4-phenylbut-1-en-1-yl]-2-oxo-1,3-oxazinan-3-yl}heptanoate; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole With benzo[1,3,2]dioxaborole In toluene at -78℃; for 1h;
Stage #2: isopropyl 7-[(4R)-4-formyl-2-oxo-1,3-oxazinan-3-yl]heptanoate In toluene at -78℃; for 1h;
Stage #3: With hydrogenchloride In water; toluene
(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

(S)-methyloxazaborolidine

(S)-methyloxazaborolidine

Conditions
ConditionsYield
With dimethylsulfide borane complex In toluene at 20℃; for 0.5h;
1-(4′-fluoro[1,1′-biphenyl]-2-yl)ethan-1-one
552885-75-3

1-(4′-fluoro[1,1′-biphenyl]-2-yl)ethan-1-one

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole
112022-81-8

(S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole

A

C14H13FO

C14H13FO

B

C14H13FO

C14H13FO

Conditions
ConditionsYield
Stage #1: (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole With borane-THF In tetrahydrofuran at -30℃; for 1h; Inert atmosphere;
Stage #2: 1-(4′-fluoro[1,1′-biphenyl]-2-yl)ethan-1-one In tetrahydrofuran at -30℃; for 1h; Overall yield = 86 %; Overall yield = 1.8 g;
A n/a
B n/a

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