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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2,4,5-Trifluoro-3-methoxybenzoic acid Manufacturer/High quality/Best price/In stock

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,4,5-Trifluoro-3-Methoxybenzoic Acid supplier in China

Cas:112811-65-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or light yellow crystalline powder Storage:cool dry place Package:25kg/drum Application:pharmaceutical inte

Manufacturer high quality 2,4,5-Trifluoro-3-methoxybenzoic acid Cas 112811-65-1 with good price

Cas:112811-65-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 112811-65-1 Benzoic acid,2,4,5-trifluoro-3-methoxy-

Cas:112811-65-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2,4,5-Trifluoro-3-methoxybenzoic acid Manufacturer/High quality/Best price/In stock

Cas:112811-65-1

Min.Order:1 Gram

FOB Price: $1.0 / 99.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 112811-65-1 with best quality

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

2,4,5-Trifluoro-3-methoxybenzoic acid CAS112811-65-1

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

ame 2,4,5-Trifluoro-3-methoxybenzoic acid Other name 3-Methoxy-2,4,5-trifluorobenzoic acid ;2,4,5-Trifluoro-m-anisic Acid CAS

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,2,4,5-trifluoro-3-methoxy- 112811-65-1

Cas:112811-65-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 2,4,5-Trifluoro-3-methoxybenzoic acid CAS:112811-65-1

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $42.0 / 48.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

2,4,5-Trifluoro-3-methoxybenzoic acid CAS:112811-65-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qu

2,4,5-Trifluoro-3-methoxybenzoic acid CAS:112811-65-1

Cas:112811-65-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,2,4,5-trifluoro-3-methoxy-

Cas:112811-65-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoic acid,2,4,5-trifluoro-3-methoxy-

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,4,5-Trifluoro-3-Methoxybenzoic Acid

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2,4,5-TRIFLUORO-3-METHOXYBENZOIC ACID

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,4,5-Trifluoro-3-Methoxybenzoic Acid

Cas:112811-65-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,4,5-Trifluoro-3-methoxybenzoicacid

Cas:112811-65-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

2,4,5-Trifluoro-3-methoxybenzoic acid Basic information Product Name: 2,4,5-Trifluoro-3-methoxybenzoic acid Synonyms: 3-Methoxyl-2,4,5-TrfluorbenzylAcid;3-METHOXY-2,4,5-TRIFLUOROBENZOYL CHLORIDE;3-Methoxy-2,4,5-trifluoroenzoic acid;2,4,5-Tetra

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

2,4,5-Trifluoro-3-methoxybenzoic Acid

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Trading Company

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Benzoic acid,2,4,5-trifluoro-3-methoxy-

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,4,5-Trifluoro-3-methoxybenzoic acid

Cas:112811-65-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white to light yellow crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Interme

2,4,5-Trifluoro-3-methoxybenzoic acid supplier in China

Cas:112811-65-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Synthetic route

Tri-n-octylamine
1116-76-3

Tri-n-octylamine

4-methoxy-3,5,6-trifluorophthalic acid
28889-41-0

4-methoxy-3,5,6-trifluorophthalic acid

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With sodium hydroxide87%
2,4,5-trifluoro-3-hydroxybenzoic acid
116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With potassium dihydrogenphosphate; N-ethyl-N,N-diisopropylamine In water at 170℃; for 8h; Reagent/catalyst; Solvent; Temperature; Autoclave;85.2%
Stage #1: 2,4,5-trifluoro-3-hydroxybenzoic acid; carbonic acid dimethyl ester With sodium hydroxide at 55 - 60℃; for 2h; pH=8 - 10; Large scale;
Stage #2: With hydrogenchloride In water at 35℃; Large scale;
85%
methyl 3-methoxy-2,4,5-trifluorobenzoate
136897-64-8

methyl 3-methoxy-2,4,5-trifluorobenzoate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol for 3h; Ambient temperature;61%
With sodium hydroxide In methanol
2,4,5-trifluoro-3-methoxy-benzamide
112811-64-0

2,4,5-trifluoro-3-methoxy-benzamide

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With sodium hydroxide In water
With sulfuric acid
With sulfuric acid at 100℃; for 3.5h;
3-methoxy-2,4,5-trifluorobenzonitrile
112811-63-9

3-methoxy-2,4,5-trifluorobenzonitrile

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water
Multi-step reaction with 2 steps
1: sulfuric acid; water / 1 h / 110 °C
2: sulfuric acid / 3.5 h / 100 °C
View Scheme
1-bromo-2,4,5-trifluoro-3-methoxybenzene
13332-24-6

1-bromo-2,4,5-trifluoro-3-methoxybenzene

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1-methyl-pyrrolidin-2-one / 4.5 h / 140 - 150 °C
2: sulfuric acid; water / 1 h / 110 °C
3: sulfuric acid / 3.5 h / 100 °C
View Scheme
N-methyl-tetrafluorophthalimide
33795-85-6

N-methyl-tetrafluorophthalimide

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / 10 h / Reflux
1.2: 8 h / 70 - 105 °C
2.1: 2 h / 35 - 80 °C / pH 8.55 - > 12 / Alkaline conditions
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide; zinc(II) chloride / water / 8 h / 100 °C / Large scale
2: hydrogenchloride / Reflux
3: sodium hydroxide / 2 h / 55 - 60 °C / pH 8 - 10
4: hydrogenchloride / water
View Scheme
Multi-step reaction with 3 steps
1.1: water; zinc(II) chloride; sodium hydroxide / 8 h / 100 °C / Large scale
2.1: hydrogenchloride / water / Reflux
3.1: sodium hydroxide / 2 h / 55 - 60 °C / pH 8 - 10 / Large scale
3.2: 35 °C / Large scale
View Scheme
2,4,5-trifluoro-3-hydroxybenzoic acid
116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
at 35 - 80℃; for 2h; pH=8.55 - > 12; Temperature; pH-value; Alkaline conditions;
3,4,5,6-tetrafluorophthalic acid
652-03-9

3,4,5,6-tetrafluorophthalic acid

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 9 h / 90 °C
1.2: 7 h / 140 °C / 7500.75 Torr / pH 1
2.1: N-ethyl-N,N-diisopropylamine; potassium dihydrogenphosphate / water / 8 h / 170 °C / Autoclave
View Scheme
C8F3O5(3-)*3Na(1+)

C8F3O5(3-)*3Na(1+)

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / Reflux
2: sodium hydroxide / 2 h / 55 - 60 °C / pH 8 - 10
3: hydrogenchloride / water
View Scheme
2,4,5-trifluoro-3-hydroxybenzoic acid
116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / 2 h / 55 - 60 °C / pH 8 - 10
2: hydrogenchloride / water
View Scheme
C8H4F3O3(1-)*Na(1+)

C8H4F3O3(1-)*Na(1+)

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Conditions
ConditionsYield
With hydrogenchloride In water818.86 mg
3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

2,4,5-trifluoro-3-methoxybenzoyl chloride
112811-66-2

2,4,5-trifluoro-3-methoxybenzoyl chloride

Conditions
ConditionsYield
With thionyl chloride for 2h; Reflux;100%
With thionyl chloride; sodium chloride In ethyl acetate Reflux;98%
With phosgene In dichloromethane at 40℃; for 5h; Solvent; Temperature;98.7%
3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

2,4,5-trifluoro-3-methoxy-benzamide
112811-64-0

2,4,5-trifluoro-3-methoxy-benzamide

Conditions
ConditionsYield
Stage #1: 3-methoxy-2,4,5-trifluorobenzoic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1.5h;
Stage #2: With ammonia In dichloromethane at 0℃; for 2h;
100%
Multi-step reaction with 2 steps
1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 20 h / 20 °C
2: ammonia / tetrahydrofuran / 1.17 h / -50 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
2: ammonium hydroxide / dichloromethane / 2.5 h / 0 - 20 °C
View Scheme
ethanol
64-17-5

ethanol

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

ethyl 2,4,5-trifluoro-3-methoxybenzoate
351354-45-5

ethyl 2,4,5-trifluoro-3-methoxybenzoate

Conditions
ConditionsYield
With sulfuric acid at 80℃; for 18h;99%
With sulfuric acid at 80℃; for 18h;99%
With sulfuric acid for 20h; Heating / reflux;91%
2-methoxyphenyl 2-chloroacetate
30287-15-1

2-methoxyphenyl 2-chloroacetate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

C17H12ClF3O5
1434871-02-9

C17H12ClF3O5

Conditions
ConditionsYield
With methanesulfonic acid; phosphorus pentoxide at 50℃; for 14h; Friedel-Crafts Acylation; Inert atmosphere;90%
With eaton’s reagent at 60℃;90%
triphenyltin chloride
639-58-7

triphenyltin chloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(triphenyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]

[(triphenyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; triphenyltin chloride added to mixt. (in 1:1:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;88%
trimethyltin(IV)chloride
1066-45-1

trimethyltin(IV)chloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(trimethyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]n
919299-24-4

[(trimethyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]n

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; trimethyltin chloride added to mixt. (in 1:1:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;87%
dimethyltin dichloride
753-73-1

dimethyltin dichloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(dimethyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

[(dimethyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; dimethyltin dichloride added to mixt. (in 2:2:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;85%
dibenzyltin(IV) dichloride
3002-01-5

dibenzyltin(IV) dichloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(dibenzyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

[(dibenzyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; dibenzyltin dichloride added to mixt. (in 2:2:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;85%
diphenyltin(IV) dichloride
1135-99-5

diphenyltin(IV) dichloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(diphenyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

[(diphenyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; diphenyltin dichloride added to mixt. (in 2:2:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;83%
ethyl (E)-3-(dimethylamino)acrylate
1117-37-9

ethyl (E)-3-(dimethylamino)acrylate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

Ethyl 3-dimethylamino-2-(3-methoxy-2,4,5-trifluorobenzoyl) acrylate
121577-35-3

Ethyl 3-dimethylamino-2-(3-methoxy-2,4,5-trifluorobenzoyl) acrylate

Conditions
ConditionsYield
With thionyl chloride; triethylamine In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; toluene81.6%
6-chloronicotinylaldehyde
23100-12-1

6-chloronicotinylaldehyde

12-(tert-butoxycarbonylamino)dodecylisocyanide
1026147-10-3

12-(tert-butoxycarbonylamino)dodecylisocyanide

2,4-Dimethoxybenzylamine
20781-20-8

2,4-Dimethoxybenzylamine

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

tert-butyl 12-(2-(N-(2,4-dimethoxybenzyl)-2,4,5-trifluoro-3-methoxybenzamido)-2-(6-chloropyridin-3-yl)acetamido)dodecylcarbamate
1026147-15-8

tert-butyl 12-(2-(N-(2,4-dimethoxybenzyl)-2,4,5-trifluoro-3-methoxybenzamido)-2-(6-chloropyridin-3-yl)acetamido)dodecylcarbamate

Conditions
ConditionsYield
Stage #1: 6-chloronicotinylaldehyde; 2,4-Dimethoxybenzylamine at 20℃; for 0.416667h;
Stage #2: 12-(tert-butoxycarbonylamino)dodecylisocyanide; 3-methoxy-2,4,5-trifluorobenzoic acid at 60℃; for 0.5h; Further stages.;
81%
dibutyltin chloride
683-18-1

dibutyltin chloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(di-n-butyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

[(di-n-butyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))2]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; di-n-butyltin dichloride added to mixt. (in 2:2:1molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;80%
di(n-butyl)tin oxide
818-08-6

di(n-butyl)tin oxide

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

C64H88F12O14Sn4*C64H88F12O14Sn4

C64H88F12O14Sn4*C64H88F12O14Sn4

Conditions
ConditionsYield
In ethanol at 50 - 65℃; for 18h; Temperature; Time;80%
tributyltin chloride
1461-22-9

tributyltin chloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(tri-n-butyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]n
919299-25-5

[(tri-n-butyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]n

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; tri-n-butyltin chloride added to mixt. (in 1:1:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;78%
tribenzyltin(IV) chloride
3151-41-5

tribenzyltin(IV) chloride

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

[(tribenzyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]

[(tribenzyltin)(2,4,5-trifluoro-3-methoxybenzoic acid(-H)(1-))]

Conditions
ConditionsYield
With sodium ethoxide In benzene (N2); organic ligand, sodium ethoxide added in benzene to a Schlenk flask; stirred for 10 min; tribenzyltin chloride added to mixt. (in 1:1:1 molar ratio); stirred for 12 h at 40°C; filtered; filtrate gradually evapd.; recrystallized from ether-petroleum; elem. anal.;77%
N-(2,6-dimethoxyphenyl)acetamide
131157-26-1

N-(2,6-dimethoxyphenyl)acetamide

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

C18H16F3NO5
1434871-04-1

C18H16F3NO5

Conditions
ConditionsYield
With methanesulfonic acid; phosphorus pentoxide at 50℃; for 14h; Friedel-Crafts Acylation; Inert atmosphere;76%
piperonal
120-57-0

piperonal

12-(tert-butoxycarbonylamino)dodecylisocyanide
1026147-10-3

12-(tert-butoxycarbonylamino)dodecylisocyanide

2,4-Dimethoxybenzylamine
20781-20-8

2,4-Dimethoxybenzylamine

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

tert-butyl 12-(2-(N-(2,4-dimethoxybenzyl)-2,4,5-trifluoro-3-methoxybenzamido)-2-(benzo[d][1,3]dioxol-5-yl)acetamido)dodecylcarbamate
1026147-16-9

tert-butyl 12-(2-(N-(2,4-dimethoxybenzyl)-2,4,5-trifluoro-3-methoxybenzamido)-2-(benzo[d][1,3]dioxol-5-yl)acetamido)dodecylcarbamate

Conditions
ConditionsYield
Stage #1: piperonal; 2,4-Dimethoxybenzylamine at 20℃; for 0.416667h;
Stage #2: 12-(tert-butoxycarbonylamino)dodecylisocyanide; 3-methoxy-2,4,5-trifluorobenzoic acid at 60℃; for 0.6h; Further stages.;
74%
3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-butyl (2,4,5-trifluoro-3-methoxyphenyl)carbamate

tert-butyl (2,4,5-trifluoro-3-methoxyphenyl)carbamate

Conditions
ConditionsYield
With diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine In toluene at 0 - 100℃; for 16h;74%
2,6-dimethoxyphenyl chloroacetate
1440-81-9

2,6-dimethoxyphenyl chloroacetate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

(2,3-dihydroxy-4-methoxyphenyl)(2,4,5-trifluoro-3-methoxyphenyl)methanone
1434871-03-0

(2,3-dihydroxy-4-methoxyphenyl)(2,4,5-trifluoro-3-methoxyphenyl)methanone

Conditions
ConditionsYield
With methanesulfonic acid; phosphorus pentoxide at 50℃; for 12h; Friedel-Crafts Acylation; Inert atmosphere;71%
1-methyl-pyrrolidin-2-one
872-50-4

1-methyl-pyrrolidin-2-one

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

2,3,6-trifluoroanisole
4920-34-7

2,3,6-trifluoroanisole

Conditions
ConditionsYield
In water70%
6-chloronicotinylaldehyde
23100-12-1

6-chloronicotinylaldehyde

12-(tert-butoxycarbonylamino)dodecylisocyanide
1026147-10-3

12-(tert-butoxycarbonylamino)dodecylisocyanide

4-methoxy-aniline
104-94-9

4-methoxy-aniline

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

tert-butyl 12-(2-(6-chloropyridin-3-yl)-2-(2,4,5-trifluoro-3-methoxy-N-(4-methoxyphenyl)benzamido)acetamido)dodecylcarbamate
1026147-25-0

tert-butyl 12-(2-(6-chloropyridin-3-yl)-2-(2,4,5-trifluoro-3-methoxy-N-(4-methoxyphenyl)benzamido)acetamido)dodecylcarbamate

Conditions
ConditionsYield
Stage #1: 6-chloronicotinylaldehyde; 4-methoxy-aniline at 20℃; for 0.333333h;
Stage #2: 12-(tert-butoxycarbonylamino)dodecylisocyanide; 3-methoxy-2,4,5-trifluorobenzoic acid at 60℃; for 0.7h; Further stages.;
61%
europium(III) nitrate hexahydrate

europium(III) nitrate hexahydrate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

3C8H4F3O3(1-)*H2O*Eu(3+)

3C8H4F3O3(1-)*H2O*Eu(3+)

Conditions
ConditionsYield
With sodium hydroxide In methanol; water pH=6;55.29%
gadolinium(III) nitrate hexahydrate

gadolinium(III) nitrate hexahydrate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

3C8H4F3O3(1-)*H2O*Gd(3+)

3C8H4F3O3(1-)*H2O*Gd(3+)

Conditions
ConditionsYield
With sodium hydroxide In methanol; water pH=6;53.08%
piperonal
120-57-0

piperonal

12-(tert-butoxycarbonylamino)dodecylisocyanide
1026147-10-3

12-(tert-butoxycarbonylamino)dodecylisocyanide

4-methoxy-aniline
104-94-9

4-methoxy-aniline

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

tert-butyl 12-(2-(benzo[d][1,3]dioxol-5-yl)-2-(2,4,5-trifluoro-3-methoxy-N-(4-methoxyphenyl)benzamido)acetamido)dodecylcarbamate
1026147-22-7

tert-butyl 12-(2-(benzo[d][1,3]dioxol-5-yl)-2-(2,4,5-trifluoro-3-methoxy-N-(4-methoxyphenyl)benzamido)acetamido)dodecylcarbamate

Conditions
ConditionsYield
Stage #1: piperonal; 4-methoxy-aniline at 20℃; for 0.333333h;
Stage #2: 12-(tert-butoxycarbonylamino)dodecylisocyanide; 3-methoxy-2,4,5-trifluorobenzoic acid at 60℃; for 0.7h; Further stages.;
53%
terbium(III) nitrate hexahydrate

terbium(III) nitrate hexahydrate

3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

3C8H4F3O3(1-)*Tb(3+)*H2O

3C8H4F3O3(1-)*Tb(3+)*H2O

Conditions
ConditionsYield
With sodium hydroxide In methanol; water pH=6;46.05%
3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-2-methylsulfanyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
922492-57-7

ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-2-methylsulfanyl-4-oxo-1,4-dihydroquinoline-3-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: oxalyl chloride; DMF / CH2Cl2 / 20 °C
2.1: n-BuLi / hexane; tetrahydrofuran / -78 °C
2.2: hexane; tetrahydrofuran; CH2Cl2 / -78 - 10 °C
3.1: sodium hydride / dimethylformamide / 0 - 20 °C
3.2: 92 percent / dimethylformamide / 24 h / 20 °C
4.1: sodium hydride / dimethylformamide / 75 °C
View Scheme
Multi-step reaction with 4 steps
1.1: thionyl chloride; sodium chloride / ethyl acetate / 4 h / Reflux; Inert atmosphere
2.1: magnesium chloride / ethyl acetate / 0.5 h / 20 °C / Inert atmosphere
2.2: 0.5 h / 20 °C / Inert atmosphere
2.3: 2 h / Inert atmosphere; Reflux
3.1: potassium hydroxide; tetrabutylammomium bromide / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere
3.2: 16 h / 0 - 20 °C / Inert atmosphere
3.3: 3 h / Inert atmosphere
4.1: potassium tert-butylate / toluene / 16 h / Inert atmosphere; Reflux
View Scheme
3-methoxy-2,4,5-trifluorobenzoic acid
112811-65-1

3-methoxy-2,4,5-trifluorobenzoic acid

ethyl 1-cyclopropyl-6,7-difluoro-2-methanesulfinyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
922492-58-8

ethyl 1-cyclopropyl-6,7-difluoro-2-methanesulfinyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: oxalyl chloride; DMF / CH2Cl2 / 20 °C
2.1: n-BuLi / hexane; tetrahydrofuran / -78 °C
2.2: hexane; tetrahydrofuran; CH2Cl2 / -78 - 10 °C
3.1: sodium hydride / dimethylformamide / 0 - 20 °C
3.2: 92 percent / dimethylformamide / 24 h / 20 °C
4.1: sodium hydride / dimethylformamide / 75 °C
5.1: m-chloroperbenzoic acid / CH2Cl2 / 20 °C
View Scheme

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