Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------
Cas:115375-60-5
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:115375-60-5
Min.Order:1
Negotiable
Type:Other
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:115375-60-5
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o
Cas:115375-60-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:115375-60-5
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:115375-60-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry(3β)-Androsta-5,16-diene-3,17-diol 3-Acetate 17-(Trifluoromethanesulfonate) CAS:115375-60-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chem
Cas:115375-60-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:115375-60-5
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:115375-60-5
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:115375-60-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Other
inquiryJinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands
Cas:115375-60-5
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Sealed in a cool ,dry and microtherm place , avoid light . Package: 1g/bag, 5g/bag, 10g/bag, 100g/bag, 1kg/bag or as per your request Application:It
Cas:115375-60-5
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryBOC Sciences is committed to supplying cost-effective products and services. We provide Abiraterone Related Compound 4 (Prasterone Acetate Triflate). An impurity of Abiraterone, a steroid hormone involved in the steroidogenesis of progesterone, min
Cas:115375-60-5
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquirybest seller Application:API
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Manufacturers
inquiryfactory?direct?sale Application:healing drugs
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Trading Company
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirybest seller Application:API
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Trading Company
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry115375-60-5 Application:intermediate
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGood Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
best seller Application:API
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Trading Company
inquirybulk?production Application:Pharmaceutical intermediates
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Trading Company
inquirybest seller Application:API
Cas:115375-60-5
Min.Order:0
Negotiable
Type:Trading Company
inquiryiodomethyl (2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide Basic information Product Name: iodomethyl (2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-
Cas:115375-60-5
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryWuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization..Company has strong ability of research and development
Cas:115375-60-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquirytrifluoromethylsulfonic anhydride
prasterone acetate
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: prasterone acetate With potassium carbonate In toluene; benzene at 25℃; for 0.5h; Stage #2: trifluoromethylsulfonic anhydride In toluene; benzene at -18 - -15℃; for 20.33h; Reagent/catalyst; Solvent; Temperature; | 96% |
Stage #1: prasterone acetate With potassium carbonate In toluene; benzene at 25℃; for 0.5h; Stage #2: trifluoromethylsulfonic anhydride In toluene; benzene at -18 - -15℃; for 20.33h; | 96% |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In dichloromethane at 20℃; for 0.0833333h; Stage #2: With 2-methoxypyridine In dichloromethane at 20 - 30℃; for 2.5h; Reagent/catalyst; | 93% |
N,N-phenylbistrifluoromethane-sulfonimide
prasterone acetate
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: prasterone acetate With potassium hexamethylsilazane In tetrahydrofuran at -78℃; for 1h; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78℃; for 2h; | 85% |
Stage #1: prasterone acetate With potassium hexamethylsilazane In tetrahydrofuran for 0.5h; Inert atmosphere; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran for 8h; Inert atmosphere; | 70% |
With potassium hexamethylsilazane In tetrahydrofuran; toluene at -80 - 0℃; for 4h; | 850 mg |
With potassium hexamethylsilazane In tetrahydrofuran; toluene at -80 - 5℃; for 2.5h; | 64.8 g |
trifluoromethylsulfonic anhydride
prasterone acetate
A
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
B
androsta-3,5,16-trien-17-yl trifluoromethanesulfonate
Conditions | Yield |
---|---|
With 2,6-di-tert-butyl-4-methylpyridine In dichloromethane for 12h; | A 58% B 10% |
With 2,6-di-tert-butyl-4-methylpyridine In dichloromethane for 3 - 16h; Product distribution / selectivity; | |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate With 2,6-dimethylpyridine In ethyl acetate for 0.25h; Stage #2: With 2,6-dimethylpyridine In ethyl acetate for 2h; Product distribution / selectivity; |
trifluoromethylsulfonic anhydride
prasterone acetate
A
dehydroepiandrosterone
B
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In 2-Methylpentane for 0.25h; Stage #2: With triethylamine In 2-Methylpentane for 2h; Product distribution / selectivity; | |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In ethyl acetate for 0.25h; Stage #2: With 1,4-diaza-bicyclo[2.2.2]octane In ethyl acetate for 2h; Product distribution / selectivity; | |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In 1,2-dichloro-ethane for 0.25h; Stage #2: With sodium hydride In 1,2-dichloro-ethane for 2h; Product distribution / selectivity; | |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate for 0.25h; Stage #2: With triethylamine for 2h; Product distribution / selectivity; |
trifluoromethylsulfonic anhydride
prasterone acetate
A
dehydroepiandrosterone
B
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
C
androsta-3,5,16-trien-17-yl trifluoromethanesulfonate
Conditions | Yield |
---|---|
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In dichloromethane for 0.25h; Stage #2: With pyridine In dichloromethane for 2h; Product distribution / selectivity; | |
Stage #1: trifluoromethylsulfonic anhydride; prasterone acetate In ethyl acetate for 0.25h; Stage #2: With pyridine In ethyl acetate for 2h; Product distribution / selectivity; |
dehydroepiandrosterone
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 2 h / 105 - 110 °C / Inert atmosphere 2.1: potassium carbonate / toluene; benzene / 0.5 h / 25 °C 2.2: 20.33 h / -18 - -15 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: pyridine; dmap / 0.25 h / 20 °C 1.2: 6 h / 20 °C 2.1: triethylamine / dichloromethane / 2 h / 0 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: pyridine / 20 °C 2.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C 2.2: 2 h / -78 °C View Scheme |
prasterone acetate
1,1,1-trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)-sulfonyl)methanesulfonamide
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With potassium tert-butylate In tetrahydrofuran at -80 - -70℃; for 2h; Reagent/catalyst; Large scale; | 112 kg |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
3-Diethylboranylpyridine
abiraterone acetate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In tetrahydrofuran at 65℃; for 4h; Reflux; | 95% |
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In tetrahydrofuran; water for 1h; Reflux; | 95% |
With bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate In tetrahydrofuran; water at 60℃; for 1h; | 94% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
phenylboronic acid
17-phenylandrosta-5,6-dien-3β-ol 3-acetate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: phenylboronic acid With sodium carbonate In water at 75℃; Catalytic behavior; Reagent/catalyst; Time; Suzuki Coupling; Inert atmosphere; Green chemistry; | 92% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Suzuki Coupling; Inert atmosphere; | 85% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 85% |
With bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate In tetrahydrofuran; water at 60℃; for 23h; Suzuki Coupling; Inert atmosphere; | 70% |
5-methoxy-3-pyridinylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: 5-methoxy-3-pyridinylboronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 88% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
3-Diethylboranylpyridine
abiraterone acetate
Conditions | Yield |
---|---|
With sodium carbonate In tetrahydrofuran; bis(triphenylphosphine)palladium(II)-chloride | 84% |
3-fluorophenylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: 3-fluorophenylboronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 83% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 52% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 52% |
5-fluoropyridine-3-boronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: 5-fluoropyridine-3-boronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 83% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
pyrimidine 5-boronic acid
3β-acetoxy-17-(pyrimidin-5-yl)androsta-5,16-diene
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: pyrimidine 5-boronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 83% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
ethyl vinyl ether
A
(Z/E)-3β-Acetoxypregna-5,17(20)-dien-21-al
B
16-dehydropregnenolone acetate
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); triethylamine In dimethyl sulfoxide at 60℃; for 4h; | A 8% B 82% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
5-methylpyridine-3-boronic acid
C27H35NO2
Conditions | Yield |
---|---|
With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane; water at 80℃; for 1h; Suzuki Coupling; Inert atmosphere; | 82% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
(6-fluoropyridin-3-yl)boronic acid
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: (6-fluoropyridin-3-yl)boronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 81% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
3-pyridylboronic acid
abiraterone acetate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: 3-pyridylboronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 79% |
With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane; water at 80℃; for 1h; Suzuki Coupling; Inert atmosphere; | 73% |
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In water at -5 - 5℃; Inert atmosphere; Reflux; | 4.5 g |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
(meta-(trifluoromethyl)phenyl)boronic acid
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: [3-(trifluoromethyl) phenyl] boronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 79% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 61% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 61% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.25h; Inert atmosphere; | 61% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
(2-tert-butoxy-2-oxoethyl)zinc(II) bromide
((3S,8R,9S,10R,13S,14S)-3-Acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-acetic acid tert-butyl ester
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; diisobutylaluminium hydride In tetrahydrofuran; toluene 1.) 0 deg C, 5 min, 2.) room temperature, overnight; | 77% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With borane-THF In tetrahydrofuran at -10 - 20℃; for 8h; Inert atmosphere; Stage #2: With sodium perborate In tetrahydrofuran; water at 0 - 20℃; | 76% |
o-fluorophenylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With copper(l) iodide; palladium dichloride In water at 20℃; for 0.0833333h; Suzuki Coupling; Inert atmosphere; Green chemistry; Stage #2: o-fluorophenylboronic acid With sodium carbonate In water at 75℃; Suzuki Coupling; Inert atmosphere; Green chemistry; | 75% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 68% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 68% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
3,4-Dimethoxyphenylboronic acid
Conditions | Yield |
---|---|
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 65% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 65% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.25h; Inert atmosphere; | 65% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
ethyl vinyl ether
A
16-dehydropregnenolone acetate
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); triethylamine In dimethyl sulfoxide at 60℃; for 4h; | A 62% B 11% |
4-methylphenylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 58% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 58% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.25h; Inert atmosphere; | 58% |
4-Bromophenylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.25h; Inert atmosphere; | 58% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 53% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 53% |
4-fluoroboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 100℃; for 6h; Suzuki Coupling; Inert atmosphere; | 57% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.08333h; Inert atmosphere; | 57% |
With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride In toluene at 20 - 100℃; for 6.25h; Inert atmosphere; | 57% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
A
3β-acetoxyandrost-5,16-diene
Conditions | Yield |
---|---|
With [(Pd(PPh3)2)n]; diisobutylaluminium hydride; tert-butyl 2-bromozincpropionate In tetrahydrofuran; toluene 1.) 0 deg C, 5 min, 2.) room temperature, overnight; | A 54% B 9% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With pyridine; ozone In methanol; dichloromethane at -78 - 20℃; Stage #2: With dimethylsulfide In methanol; dichloromethane at -78℃; for 0.5h; | 53% |
4-carboxyphenylboronic acid
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane; water at 80 - 85℃; Inert atmosphere; | 53% |
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
Stage #1: 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate With borane-THF In tetrahydrofuran at 0℃; for 4h; Inert atmosphere; Stage #2: With sodium perborate tetrahydrate; water In tetrahydrofuran at 0 - 20℃; for 18h; Inert atmosphere; | 28% |
vinyl acetate
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
A
Acetic acid (Z)-2-((3S,8R,9S,10R,13S,14S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-vinyl ester
B
Acetic acid (E)-2-((3S,8R,9S,10R,13S,14S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-vinyl ester
Conditions | Yield |
---|---|
With triethylamine; palladium diacetate; triphenylphosphine In N,N-dimethyl-formamide at 60℃; for 9h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
α-picoline
3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate
Conditions | Yield |
---|---|
With n-butyllithium; bis(triphenylphosphine)palladium(II)-chloride; zinc(II) chloride Multistep reaction; |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View