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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyrimidine,2-chloro-4-phenyl- 13036-50-5

Cas:13036-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-CHLORO-4-PHENYLPYRIMIDINE CAS:13036-50-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

2-CHLORO-4-PHENYLPYRIMIDINE CAS:13036-50-5

Cas:13036-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyrimidine,2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyrimidine,2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-CHLORO-4-PHENYLPYRIMIDINE Basic information Product Name: 2-CHLORO-4-PHENYLPYRIMIDINE Synonyms: 2-chloro-4-phenyl-pyrimidin;2-CHLORO-4-PHENYLPYRIMIDINE;Pyrimidine, 2-chloro-4-phenyl-;2-Chloro-4-phenylpyrimidine95% CAS: 13036-50-5 MF: C1

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-chloro-4-phenylpyrimidine cas no. 13036-50-5 98%

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Pyrimidine,2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pyrimidine,2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:off-white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as prima

Pyrimidine, 2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2-CHLORO-4-PHENYLPYRIMIDINEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

13036-50-5

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei youze Biotechnology Co.,Ltd

Our Advantage 1.Best quality with competitive price. 2.Quick shipping,delivery on time. 3.We have a pharmaceutical raw material production plant and a reagent R&D center. 4.Support multiple trading methods and payment.We support wire transfer

Factory direct sale Top quality 2-Chloro-4-phenylpyrimidine CAS.13036-50-5

Cas:13036-50-5

Min.Order:1 Kilogram

FOB Price: $6.8 / 8.6

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

2-Chloro-4-phenylpyrimidine CAS NO.13036-50-5

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changzhou Pesan Chemical Co.,Ltd

Strong R&D strength and team We have a R&D team with around 30 R&D personnel.All of our employees have chemical backgrounds and have worked in the chemical industry for many years.Our laboratory can synthesize target products with wei

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Other

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl

2-Chloro-4-phenylpyrimidine

Cas:13036-50-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Trading Company

inquiry

Shandong Bolode Bio-Technology Co., LTD

productName Pyrimidine,2-chloro-4-phenyl- Synonyms 2-Chloro-4… Package:Aluminum foil bag or according to custom's requirement Application:Organic intermediates Transportation:Ship it by express. Port:China

Pyrimidine,2-chloro-4-phenyl-

Cas:13036-50-5

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

2-CHLORO-4-PHENYLPYRIMIDINE

Cas:13036-50-5

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

phenylboronic acid
98-80-6

phenylboronic acid

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium carbonate In ethanol; water at 70℃; for 10h; Catalytic behavior; Suzuki-Miyaura Coupling;87%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene for 4h; Inert atmosphere; Reflux;86%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene for 4h; Inert atmosphere; Reflux;86%
bromobenzene
108-86-1

bromobenzene

sodium 2-chloropyrimidine-4-sulfinate

sodium 2-chloropyrimidine-4-sulfinate

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate In 1,4-dioxane at 100℃; for 18h; Inert atmosphere;84%
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

phenylboronic acid
98-80-6

phenylboronic acid

A

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

B

2,4-diphenylpyrimidine
25095-48-1

2,4-diphenylpyrimidine

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In methanol; benzene for 4h; Phenylation; Heating;A 80%
B 10%
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

phenylzinc(II) bromide
38111-44-3

phenylzinc(II) bromide

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 50℃;64%
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 50℃;
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 50℃;
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

tributylphenylstannane
960-16-7

tributylphenylstannane

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 80℃; for 10h;60%
N-(1-phenylethylidene)cyanamide
34441-01-5

N-(1-phenylethylidene)cyanamide

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Stage #1: N,N-dimethyl-formamide With trichlorophosphate at 20℃; for 0.166667h; Vilsmeier Reaction;
Stage #2: N-(1-phenylethylidene)cyanamide at 20 - 130℃; for 1.5h;
60%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

phenylmagnesium chloride
100-59-4

phenylmagnesium chloride

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
In tetrahydrofuran at 25℃; for 8h;49%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

phenylboronic acid
98-80-6

phenylboronic acid

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With manganese(III) triacetate dihydrate In ethanol at 170℃; for 0.166667h; Microwave irradiation; regioselective reaction;48%
2-Amino-4-phenylpyrimidine 1-Oxide
80830-43-9

2-Amino-4-phenylpyrimidine 1-Oxide

A

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

B

2-chloro-4-phenylpyrimidine 1-oxide
85658-58-8

2-chloro-4-phenylpyrimidine 1-oxide

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite at 0℃; for 2h;A 12%
B 46%
With hydrogenchloride; lithium chloride; sodium nitrite In acetic acidA 12%
B 46%
4-phenylpyrimidin-2-amine
2305-87-5

4-phenylpyrimidin-2-amine

A

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

B

2-hydroxy-4-phenylpyrimidine
38675-31-9

2-hydroxy-4-phenylpyrimidine

Conditions
ConditionsYield
With hydrogenchloride; lithium chloride; sodium nitrite In acetic acidA 35%
B 20%
4-phenyl-1H-pyrimidin-2-one
38675-31-9

4-phenyl-1H-pyrimidin-2-one

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With trichlorophosphate
2,4-dichloro-6-phenyl-pyrimidine
26032-72-4

2,4-dichloro-6-phenyl-pyrimidine

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With ammonia; zinc
4-phenylpyrimidin-2-amine
2305-87-5

4-phenylpyrimidin-2-amine

A

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

B

2-hydroxy-4-phenylpyrimidine
38675-31-9

2-hydroxy-4-phenylpyrimidine

C

5-bromo-2-amino-4-phenylpyrimidine
85658-55-5

5-bromo-2-amino-4-phenylpyrimidine

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 0 - 5℃; Product distribution; Mechanism; other acids; other temepratures;
2-Amino-4-phenylpyrimidine 1-Oxide
80830-43-9

2-Amino-4-phenylpyrimidine 1-Oxide

A

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

B

2-chloro-4-phenylpyrimidine 1-oxide
85658-58-8

2-chloro-4-phenylpyrimidine 1-oxide

C

5-chloro-2-amino-4-phenylpyrimidine 1-oxide
85658-57-7

5-chloro-2-amino-4-phenylpyrimidine 1-oxide

D

5-bromo-2-amino-4-phenylpyrimidine 1-oxide
85658-56-6

5-bromo-2-amino-4-phenylpyrimidine 1-oxide

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 0 - 5℃; Product distribution; Mechanism; other acids; other temepratures;
2-Chloro-6-phenyl-1,6-dihydro-pyrimidine

2-Chloro-6-phenyl-1,6-dihydro-pyrimidine

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; diethyl ether for 0.0833333h; Ambient temperature; Yield given;
phenyllithium
591-51-5

phenyllithium

2-<5-chloro-1(3)H-benzimidazol-2-yl>-3-hydroxy-inden-1-one

2-<5-chloro-1(3)H-benzimidazol-2-yl>-3-hydroxy-inden-1-one

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diethyl ether / 1 h / 1.) -30 deg C, 30 min, 2.) 0 deg C, 30 min
2: 2,3-dichloro-5,6-dicyanobenzoquinone / diethyl ether; tetrahydrofuran / 0.08 h / Ambient temperature
View Scheme
4-phenylpyrimidin-2-amine
2305-87-5

4-phenylpyrimidin-2-amine

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous H2SO4; aqueous NaNO2
2: POCl3
View Scheme
6-phenyluracil
13345-09-0

6-phenyluracil

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: POCl3
2: zinc-powder; aq.-ethanolic NH3
View Scheme
2-methylthio-6-phenyl-3,4-dihydropyrimidin-4-one
56035-29-1

2-methylthio-6-phenyl-3,4-dihydropyrimidin-4-one

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aqueous H2SO4 / 140 - 150 °C
2: POCl3
3: zinc-powder; aq.-ethanolic NH3
View Scheme
3-Oxo-3-phenylpropanal
15397-33-8

3-Oxo-3-phenylpropanal

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine
2: aqueous H2SO4; aqueous NaNO2
3: POCl3
View Scheme
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

phenyllithium
591-51-5

phenyllithium

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
With bunazosin In tetrahydrofuran at -78 - 0℃; for 3h;
acetophenone oxime
613-91-2

acetophenone oxime

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 0 °C
2.1: fac-tris(2-(4'-tert-butyl)phenylpyridine)iridium(III); tetrakis(acetonitrile)copper(I)tetrafluoroborate; 1,10-Phenanthroline / chlorobenzene / 24 h / 25 °C / Inert atmosphere; Sealed tube; Irradiation
3.1: trichlorophosphate / 0.17 h / 20 °C
3.2: 1.5 h / 20 - 130 °C
View Scheme
1-phenylethan-1-one O-(4-(trifluoromethyl)benzoyl) oxime

1-phenylethan-1-one O-(4-(trifluoromethyl)benzoyl) oxime

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: fac-tris(2-(4'-tert-butyl)phenylpyridine)iridium(III); tetrakis(acetonitrile)copper(I)tetrafluoroborate; 1,10-Phenanthroline / chlorobenzene / 24 h / 25 °C / Inert atmosphere; Sealed tube; Irradiation
2.1: trichlorophosphate / 0.17 h / 20 °C
2.2: 1.5 h / 20 - 130 °C
View Scheme
acetophenone
98-86-2

acetophenone

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydroxylamine hydrochloride; sodium acetate / methanol / 75 °C
2.1: triethylamine / dichloromethane / 0 °C
3.1: fac-tris(2-(4'-tert-butyl)phenylpyridine)iridium(III); tetrakis(acetonitrile)copper(I)tetrafluoroborate; 1,10-Phenanthroline / chlorobenzene / 24 h / 25 °C / Inert atmosphere; Sealed tube; Irradiation
4.1: trichlorophosphate / 0.17 h / 20 °C
4.2: 1.5 h / 20 - 130 °C
View Scheme
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

4-phenyl-1H-pyrimidin-2-one
38675-31-9

4-phenyl-1H-pyrimidin-2-one

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 1h;100%
With hydrogenchloride In water Reflux;55%
With hydrogenchloride In water for 1h; Reflux;
With hydrogenchloride In water for 1h; Reflux;
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

(±)-trans-methyl 2-(((6-(5-(aminomethyl)-1-methyl-1H-1,2,3-triazol-4-yl)-2-methylpyridin-3-yl)oxy)methyl)cyclobutanecarboxylate

(±)-trans-methyl 2-(((6-(5-(aminomethyl)-1-methyl-1H-1,2,3-triazol-4-yl)-2-methylpyridin-3-yl)oxy)methyl)cyclobutanecarboxylate

(±)-(1R,2R)-2-(((2-methyl-6-(1-methyl-5-(((4-phenylpyrimidin-2-yl)amino)methyl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)methyl)cyclobutanecarboxylic acid

(±)-(1R,2R)-2-(((2-methyl-6-(1-methyl-5-(((4-phenylpyrimidin-2-yl)amino)methyl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)methyl)cyclobutanecarboxylic acid

Conditions
ConditionsYield
Stage #1: 2-chloro-4-phenylpyrimidine; (±)-trans-methyl 2-(((6-(5-(aminomethyl)-1-methyl-1H-1,2,3-triazol-4-yl)-2-methylpyridin-3-yl)oxy)methyl)cyclobutanecarboxylate With N-ethyl-N,N-diisopropylamine In butan-1-ol at 180℃; for 1.33333h;
Stage #2: With lithium hydroxide monohydrate; water In tetrahydrofuran; methanol at 20℃;
97%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-fluoro-4-phenylpyrimidine
38953-34-3

2-fluoro-4-phenylpyrimidine

Conditions
ConditionsYield
With 18-crown-6 ether; tetramethlyammonium chloride; cesium fluoride In acetonitrile at 60℃; for 16h; Glovebox;97%
With tetramethylammonium fluoride In dimethyl sulfoxide at 80℃; for 24h; Inert atmosphere; Sealed tube;90%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-(4-methylpiperazin-1-yl)-4-phenylpyrimidine

2-(4-methylpiperazin-1-yl)-4-phenylpyrimidine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 90℃; for 1.5h; Inert atmosphere;95%
In N,N-dimethyl-formamide at 90℃; for 1.5h; Inert atmosphere;95%
In ethanol for 0.5h; Heating;
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-Cyclopropyl-4,5-dihydro-1H-imidazol
109152-85-4

2-Cyclopropyl-4,5-dihydro-1H-imidazol

C16H16N4
1375748-11-0

C16H16N4

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 100℃; Buchwald-Hartwig arylation; Inert atmosphere;92%
4,4,5,5,-tetramethyl-2-[4-(phenylmethoxy)phenyl]-1,3,2-dioxaborolane

4,4,5,5,-tetramethyl-2-[4-(phenylmethoxy)phenyl]-1,3,2-dioxaborolane

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-(4-(benzyloxy)phenyl)-4-phenylpyrimidine
1351933-85-1

2-(4-(benzyloxy)phenyl)-4-phenylpyrimidine

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; lithium hydroxide In 1,4-dioxane; water at 80℃; for 0.5h; Suzuki-Miyaura cross-coupling; Inert atmosphere;89%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

5-(1H-imidazol-1-yl)-2-methylaniline

5-(1H-imidazol-1-yl)-2-methylaniline

N-(5-(1H-imidazol-1-yl)-2-methylphenyl)-4-phenylpyrimidin-2-amine

N-(5-(1H-imidazol-1-yl)-2-methylphenyl)-4-phenylpyrimidin-2-amine

Conditions
ConditionsYield
With potassium hexamethylsilazane In tetrahydrofuran at 100℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube; Green chemistry;89%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-hydroxy-4-phenylpyrimidine
38675-31-9

2-hydroxy-4-phenylpyrimidine

Conditions
ConditionsYield
With acetylhydroxamic acid; potassium carbonate In dimethyl sulfoxide at 80℃; for 12h; Sealed tube;87%
With hydrogenchloride; water at 100℃; for 1h;
With hydrogenchloride; water at 100℃; for 1h;
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

4-nitrophenylboronic acid
24067-17-2

4-nitrophenylboronic acid

2-(4-nitrophenyl)-4-phenylpyrimidine
1351665-18-3

2-(4-nitrophenyl)-4-phenylpyrimidine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; acetonitrile at 90℃;84%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

tri-n-butyl(vinyl)tin
7486-35-3

tri-n-butyl(vinyl)tin

4-phenyl-2-vinylpyrimidine

4-phenyl-2-vinylpyrimidine

Conditions
ConditionsYield
With palladium diacetate; triphenylphosphine In tetrahydrofuran for 18h; Reflux;83%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

sodium methylate
124-41-4

sodium methylate

2-methoxy-4-phenylpyrimidine
78009-15-1

2-methoxy-4-phenylpyrimidine

Conditions
ConditionsYield
for 4h; Heating;80%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-amino-N-(4-methoxybenzyl)-N-methylacetamide hydrochloride

2-amino-N-(4-methoxybenzyl)-N-methylacetamide hydrochloride

N-(4-methoxybenzyl)-N-methyl-2-((4-phenylpyrimidin-2-yl)amino)acetamide

N-(4-methoxybenzyl)-N-methyl-2-((4-phenylpyrimidin-2-yl)amino)acetamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 95℃; for 16h; Inert atmosphere;80%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

3-amino-1-ethylazepan-2-one hydrochloride

3-amino-1-ethylazepan-2-one hydrochloride

1-ethyl-3-((4-phenylpyrimidin-2-yl)amino)azepan-2-one

1-ethyl-3-((4-phenylpyrimidin-2-yl)amino)azepan-2-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 95℃; for 16h; Inert atmosphere;79%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

4-aminophenylacetic acid
1197-55-3

4-aminophenylacetic acid

2-(4-(4-phenylpyrimidin-2-ylamino)phenyl)acetic acid
1129540-67-5

2-(4-(4-phenylpyrimidin-2-ylamino)phenyl)acetic acid

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; water at 160℃; for 10h; Microwave irradiation; in a seal tube;77%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-amino-1-(morpholin-4-yl)ethanone hydrochloride
24152-96-3

2-amino-1-(morpholin-4-yl)ethanone hydrochloride

1-morpholino-2-((4-phenylpyrimidin-2-yl)amino)ethanone

1-morpholino-2-((4-phenylpyrimidin-2-yl)amino)ethanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 100℃; for 12h; Inert atmosphere; Sealed tube;74.5%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

1-butyn-4-ol
927-74-2

1-butyn-4-ol

2-but-3-ynyloxy-4-phenylpyrimidine
1356542-31-8

2-but-3-ynyloxy-4-phenylpyrimidine

Conditions
ConditionsYield
Stage #1: 3-Butyn-1-ol With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: 2-chloro-4-phenylpyrimidine In tetrahydrofuran at 20℃;
71%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

m-aminobenzenesulfonamide
98-18-0

m-aminobenzenesulfonamide

3-[(4-phenylpyrimidin-2-yl)amino]benzene-1-sulfonamide

3-[(4-phenylpyrimidin-2-yl)amino]benzene-1-sulfonamide

Conditions
ConditionsYield
With acetic acid In butan-1-ol at 110℃; for 21h;70%
With trifluoroacetic acid In isopropyl alcohol for 18h; Sealed tube; Heating;39%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-amino-N,N-dimethylpropanamide hydrochloride
1219200-57-3

2-amino-N,N-dimethylpropanamide hydrochloride

N,N-dimethyl-2-((4-phenylpyrimidin-2-yl)amino)propanamide

N,N-dimethyl-2-((4-phenylpyrimidin-2-yl)amino)propanamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 100℃; for 16h; Inert atmosphere;69%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

(2-phenylvinyl)tributylstannane
66680-87-3, 66680-88-4, 79159-76-5

(2-phenylvinyl)tributylstannane

4-phenyl-2-(β-styryl)pyrimidine

4-phenyl-2-(β-styryl)pyrimidine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In N,N-dimethyl-formamide at 100℃; for 10h;68%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-amino-1-(4-benzylpiperazin-1-yl)ethanone dihydrochloride

2-amino-1-(4-benzylpiperazin-1-yl)ethanone dihydrochloride

1-(4-benzylpiperazin-1-yl)-2-((4-phenylpyrimidin-2-yl)amino)ethanone

1-(4-benzylpiperazin-1-yl)-2-((4-phenylpyrimidin-2-yl)amino)ethanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 110℃; for 16h; Inert atmosphere;68%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

C30H19N3

C30H19N3

C40H25N5

C40H25N5

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 12h; Inert atmosphere; Heating;65%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

2-amino-N,N-dimethyl-acetamide hydrochloride
72287-77-5

2-amino-N,N-dimethyl-acetamide hydrochloride

N,N-dimethyl-2-((4-phenylpyrimidin-2-yl)amino)acetamide

N,N-dimethyl-2-((4-phenylpyrimidin-2-yl)amino)acetamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 100℃; for 16h; Inert atmosphere;63%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

4-(2-(2-pyridinyl)ethenyl)phenol
1209-03-6

4-(2-(2-pyridinyl)ethenyl)phenol

4-phenyl-2-(4-(2-(2-pyridinyl)ethenyl)phenoxy)pyrimidine

4-phenyl-2-(4-(2-(2-pyridinyl)ethenyl)phenoxy)pyrimidine

Conditions
ConditionsYield
With copper; caesium carbonate In N,N-dimethyl-formamide at 110℃; for 6h; Inert atmosphere;63%
2-Amino-4-methylpyridine
695-34-1

2-Amino-4-methylpyridine

2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

N-(4-methylpyridin-2-yl)-4-phenylpyrimidin-2-amine
1236002-80-4

N-(4-methylpyridin-2-yl)-4-phenylpyrimidin-2-amine

Conditions
ConditionsYield
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 160℃; for 6h; Buchwald-Hartwig reaction; Inert atmosphere;62%
2-chloro-4-phenylpyrimidine
13036-50-5

2-chloro-4-phenylpyrimidine

N-(4-aminophenyl)-4-methoxybenzenesulfonamide
91807-29-3

N-(4-aminophenyl)-4-methoxybenzenesulfonamide

4-methoxy-N-(4-((4-phenylpyrimidin-2-yl)amino)phenyl)benzenesulfonamide

4-methoxy-N-(4-((4-phenylpyrimidin-2-yl)amino)phenyl)benzenesulfonamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 80℃;62%

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