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Dayang Chem (Hangzhou) Co.,Ltd.

img _fcksaAppearance:yellowish to pale orange crystals or cryst. powder Storage:Store in dry, dark and ventilated place. Package:according to the clients requirement Application:Pharmaceutical Intermediates Transportation:by sea or by air Port:Shan

2-Chloropyrimidine TOP1 supplier

Cas:1722-12-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product informations Product Name 2-Chloropyrimidine CAS No. 1722-12-9 Appearan

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

2-Chloropyrimidine TOP1 supplier

Cas:1722-12-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-chloropyrimidine

Cas:1722-12-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 2-Chloropyrimidine 1722-12-9 ISO Manufacturer

Cas:1722-12-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--1722-12-9--2-Chloropyrimidine factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business rel

TIANFUCHEM--1722-12-9--2-Chloropyrimidine factory price

Cas:1722-12-9

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

High CAS 1722-12-9 with best price

Cas:1722-12-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2-Chloropyrimidine/ LIDE PHARMA- Factory supply / Best price

Cas:1722-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Name: 2-Chloropyrimidine Synonyms: 2-Chloro Pyridine CAS:1722-12-9 MF: C4H3ClN2 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Syntheses Material Intermediates Transportation:By

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white to light yellow crystalline powder Storage:Store in se

2-Chloropyrimidine crystalline powder CAS 1722-12-9

Cas:1722-12-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hangzhou Think Chemical Co. Ltd

2-chloropyrimidine (CAS: 1722-12-9) Name 2-Chloropyrimidine Molecular Structure Molecular Formula C4H3ClN2 Molecular Weight 114.53 CAS Registry Numb

2-chloropyrimidine

Cas:1722-12-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Chloropyrimidine 1722-12-9

Cas:1722-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2-Chloropyrimidine 99%

Cas:1722-12-9

Min.Order:1 Kilogram

FOB Price: $132.0 / 150.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

2-Chloropyrimidine TOP1 supplier CAS NO.1722-12-9

Cas:1722-12-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Chloropyrimidine CAS: 1722-12-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte

2-Chloropyrimidine CAS: 1722-12-9

Cas:1722-12-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhengzhou Yuanli Biological Technology Co., Ltd.

Product Name: 2-Chloropyrimidine CAS No.:1722-12-9 MF:C7H12CIN3 MW:173.64 Assay : 98% Packaging: 1kg/Bag, 25kg/Drum or depends on your requirements. Shipping: Timely delivery after your payment Superiority : ISO certificate 2. Pow

98% 2-Chloropyrimidine factory supply

Cas:1722-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

2-Chloropyrimidine 1722-12-9

Cas:1722-12-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS1722-12-9 2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

2-Chloropyrimidine CAS 1722-12-9 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality contro

2-Chloropyrimidine CAS 1722-12-9

Cas:1722-12-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Chloropyrimidine

Cas:1722-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2-CHLOROPYRIMIDINE

Cas:1722-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-hydroxypyrimidine
557-01-7

2-hydroxypyrimidine

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With trichlorophosphate Chlorination;70%
2-sulfanylpyrimidine
131242-36-9

2-sulfanylpyrimidine

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
Stage #1: 2-sulfanylpyrimidine With trichloroisocyanuric acid; water; benzyltrimethylammonium chloride In acetonitrile at -30 - -25℃; for 0.5h;
Stage #2: With isobutylamine In acetonitrile Further stages.;
70%
With hydrogenchloride; sodium hypochlorite In dichloromethane; water
With thionyl chloride; dihydrogen peroxide In water; acetonitrile at 25℃;
(2-chloropyrimidin-5-yl)boronic acid
1003845-06-4

(2-chloropyrimidin-5-yl)boronic acid

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With 2-bromo-pyridine; tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; toluene Reflux;65%
triisobutylaluminum
100-99-2

triisobutylaluminum

5-Bromo-2-chloropyrimidine
32779-36-5

5-Bromo-2-chloropyrimidine

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-chloro-5-isobutylpyrimidine

2-chloro-5-isobutylpyrimidine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 24h; Heating;A 30%
B 50%
triethylaluminum
97-93-8

triethylaluminum

5-Bromo-2-chloropyrimidine
32779-36-5

5-Bromo-2-chloropyrimidine

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-chloro-5-ethylpyrimidine
111196-81-7

2-chloro-5-ethylpyrimidine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 24h; Heating;A 30%
B 42%
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

triethylaluminum
97-93-8

triethylaluminum

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-chloro-4-ethylpyrimidine
188707-99-5

2-chloro-4-ethylpyrimidine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 24h; Heating;A 25%
B 37%
2-aminopyrimidine
109-12-6

2-aminopyrimidine

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite In water at -15 - 0℃; for 2.25h;34%
With hydrogenchloride; sodium nitrite
With hydrogenchloride; zinc(II) chloride; sodium nitrite In dichloromethane; water
With hydrogenchloride; zinc(II) chloride; sodium nitrite In dichloromethane; water
With hydrogenchloride; copper dichloride; sodium nitrite In dichloromethane
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With zinc
With potassium acetate; palladium diacetate; bis(pinacol)diborane; tricyclohexylphosphine In 1,4-dioxane at 110℃; for 0.166667h; Inert atmosphere;
With hydrogen In methanol; ethanol at 20℃;
2-pyrimidinone hydrochloride
38353-09-2

2-pyrimidinone hydrochloride

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate
With trichlorophosphate
1-methyl-1H-pyrazole
930-36-9

1-methyl-1H-pyrazole

chloroform
67-66-3

chloroform

A

1H-pyrrole-2-carbonitrile
4513-94-4

1H-pyrrole-2-carbonitrile

B

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

C

5-chloronicotinonitrile
51269-82-0

5-chloronicotinonitrile

Conditions
ConditionsYield
at 550 - 555℃; Yield given. Title compound not separated from byproducts;
at 550 - 555℃; Title compound not separated from byproducts;
1-benzylpyrazole
10199-67-4

1-benzylpyrazole

chloroform
67-66-3

chloroform

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-phenylpyrimidine
7431-45-0

2-phenylpyrimidine

C

α-carboline
244-76-8

α-carboline

Conditions
ConditionsYield
at 550 - 555℃; Title compound not separated from byproducts;
chloroform
67-66-3

chloroform

1-benzhydryl-1H-pyrazole

1-benzhydryl-1H-pyrazole

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-phenylpyrimidine
7431-45-0

2-phenylpyrimidine

Conditions
ConditionsYield
at 550 - 555℃; Title compound not separated from byproducts;
chloroform
67-66-3

chloroform

CDD3502

CDD3502

A

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

B

2-phenylpyrimidine
7431-45-0

2-phenylpyrimidine

Conditions
ConditionsYield
at 550 - 555℃; Title compound not separated from byproducts;
chloroform
67-66-3

chloroform

1-(pyridin-4-ylmethyl)-1H-pyrazol-5-amine
202344-41-0

1-(pyridin-4-ylmethyl)-1H-pyrazol-5-amine

A

NH-pyrazole
288-13-1

NH-pyrazole

B

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

C

9H-pyrrolo[2,3-b:5,4-c']dipyridine

9H-pyrrolo[2,3-b:5,4-c']dipyridine

Conditions
ConditionsYield
at 550 - 555℃; Title compound not separated from byproducts;
at 550 - 555℃;
chloroform
67-66-3

chloroform

1-(4-chlorobenzyl)pyrazole
202344-37-4

1-(4-chlorobenzyl)pyrazole

A

NH-pyrazole
288-13-1

NH-pyrazole

B

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

C

7-chloro-9H-pyrido[2,3-b]indole

7-chloro-9H-pyrido[2,3-b]indole

D

2-(4-chlorophenyl)pyrimidine
191212-20-1

2-(4-chlorophenyl)pyrimidine

Conditions
ConditionsYield
at 550 - 555℃; Title compound not separated from byproducts;
1-(pyridin-4-ylmethyl)-1H-pyrazol-5-amine
202344-41-0

1-(pyridin-4-ylmethyl)-1H-pyrazol-5-amine

A

NH-pyrazole
288-13-1

NH-pyrazole

B

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

C

9H-pyrrolo[2,3-b:5,4-c']dipyridine

9H-pyrrolo[2,3-b:5,4-c']dipyridine

Conditions
ConditionsYield
With chloroform at 550 - 555℃; Title compound not separated from byproducts;
1-(4-chlorobenzyl)pyrazole
202344-37-4

1-(4-chlorobenzyl)pyrazole

A

NH-pyrazole
288-13-1

NH-pyrazole

B

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

C

7-chloro-9H-pyrido[2,3-b]indole

7-chloro-9H-pyrido[2,3-b]indole

D

2-(4-chlorophenyl)pyrimidine
191212-20-1

2-(4-chlorophenyl)pyrimidine

Conditions
ConditionsYield
With chloroform at 550 - 555℃; Title compound not separated from byproducts;
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

ammonia
7664-41-7

ammonia

benzene
71-43-2

benzene

zinc-powder

zinc-powder

aqueous NaCl

aqueous NaCl

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

zinc-powder

zinc-powder

aqueous NH4Cl

aqueous NH4Cl

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-Amino-4,6-dichloropyrimidine
56-05-3

2-Amino-4,6-dichloropyrimidine

4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With potassium carbonate In ethanol
2-Amino-4,6-dichloropyrimidine
56-05-3

2-Amino-4,6-dichloropyrimidine

2-(4-Methoxyphenyl)ethanol
702-23-8

2-(4-Methoxyphenyl)ethanol

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With NaH In tetrahydrofuran
2-Amino-4,6-dichloropyrimidine
56-05-3

2-Amino-4,6-dichloropyrimidine

1-(2-Chloroethyl)-4-methoxybenzene
18217-00-0

1-(2-Chloroethyl)-4-methoxybenzene

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With Na2S In water; N,N-dimethyl-formamide
2-chloro-4-(2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridin-5-yl)pyrimidine

2-chloro-4-(2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridin-5-yl)pyrimidine

Allyl chloroformate
2937-50-0

Allyl chloroformate

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
With sodium bicarbonate; trifluoroacetic acid In dichloromethane
pyrimidine-2-sulfonyl chloride

pyrimidine-2-sulfonyl chloride

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

Conditions
ConditionsYield
In chloroform-d1; water at 20℃;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
23978-55-4

1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

7,16-Di-pyrimidin-2-yl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane
130536-58-2

7,16-Di-pyrimidin-2-yl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 100℃; under 6000480 Torr; for 96h;100%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

allylmagnesium bromide
1730-25-2

allylmagnesium bromide

4-allyl-2-chloro-3,4-dihydropyrimidine
123703-54-8

4-allyl-2-chloro-3,4-dihydropyrimidine

Conditions
ConditionsYield
In tetrahydrofuran for 0.25h; Ambient temperature;100%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

ethanol
64-17-5

ethanol

2-ethoxy pyrimidine
3739-82-0

2-ethoxy pyrimidine

Conditions
ConditionsYield
With NmN'''-(butane-1,4-diyl)bisguanidine for 16h; Heating;100%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

tert.-butyl lithium
594-19-4

tert.-butyl lithium

4-(tert-butyl)-2-chloropyrimidine
66522-06-3

4-(tert-butyl)-2-chloropyrimidine

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In diethyl ether at -30 - 0℃; for 1h;100%
With acetic acid; bunazosin In tetrahydrofuran at -78℃; for 3h;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

benzoimidazole
51-17-2

benzoimidazole

1-(pyrimidin-2-yl)-1H-benzo[d]imidazole

1-(pyrimidin-2-yl)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride; 2-aminopyrimidine-4,6-diol; copper(I) bromide at 145 - 150℃; for 24h;100%
With potassium carbonate In dimethyl sulfoxide at 70℃; for 24h; Inert atmosphere;95%
With 1-methyl-3-(2-pyridinyl)-3,4,5,6-tetrahydropyrimidin-3-ium hexafluorophosphate; potassium tert-butylate; palladium diacetate In 1,2-dimethoxyethane at 100℃; for 0.666667h; Buchwald-Hartwig Coupling; Microwave irradiation;93%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-methylimidazole
693-98-1

2-methylimidazole

2-(2-methyl-1H-imidazol-1-yl)pyrimidine

2-(2-methyl-1H-imidazol-1-yl)pyrimidine

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride; 2-aminopyrimidine-4,6-diol; copper(I) bromide at 145 - 150℃; for 24h;100%
With copper(I) oxide; 1,10-Phenanthroline; tetrabutyl ammonium fluoride at 140 - 145℃; for 24h;98%
Stage #1: 2-methylimidazole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: 2-chloropyrimidine In N,N-dimethyl-formamide; mineral oil at 130℃;
89%
With potassium phosphate; benzoin oxime; copper diacetate In dimethyl sulfoxide at 80℃; Inert atmosphere;80%
With copper; caesium carbonate; methyl-alpha-D-glucopyranoside In water; dimethyl sulfoxide at 110℃; for 14h; Sealed tube; Green chemistry;80%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-pivaloylaminophenyl boronic acid
146140-95-6

2-pivaloylaminophenyl boronic acid

2,2-dimethyl-N-(2-pyrimidin-2-yl-phenyl)-propionamide
797047-16-6

2,2-dimethyl-N-(2-pyrimidin-2-yl-phenyl)-propionamide

Conditions
ConditionsYield
Stage #1: 2-chloropyrimidine; tetrakis(triphenylphosphine) palladium(0) In glyco dimethyl ether at 15 - 25℃; for 0.333333 - 0.5h;
Stage #2: 2-pivaloylaminophenyl boronic acid With sodium carbonate In 1,2-dimethoxyethane; water at 78 - 83℃; for 3h; Heating / reflux;
100%
With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water at 20 - 83℃;
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 0 - 83℃; for 4.33333 - 5.5h; Heating / reflux;
With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 83℃; for 11h;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-pyrimidinylhydrazine
7504-94-1

2-pyrimidinylhydrazine

Conditions
ConditionsYield
With potassium carbonate; hydrazine hydrate at 100℃; for 0.5h;99.8%
With hydrazine In pyridine at 25℃; for 1.5h;95%
With hydrazine hydrate In ethanol Reflux;87%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

phenol
108-95-2

phenol

2-phenoxypyrimidine
18213-90-6

2-phenoxypyrimidine

Conditions
ConditionsYield
With potassium phosphate; bis(η3-allyl-μ-chloropalladium(II)); 1,2-bis(diphenylphosphino)-1'-(diisopropylphosphino)-3',4-di-tert-butyl ferrocene In toluene at 115℃; for 20h; Inert atmosphere;99%
With copper; caesium carbonate In N,N-dimethyl-formamide at 100℃; for 0.166667h; Ullmann ether synthesis; microwave irradiation;97%
With 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate; copper(l) chloride In 1-methyl-pyrrolidin-2-one at 120℃; for 24h; Ullmann coupling; Inert atmosphere;65%
1H-imidazole
288-32-4

1H-imidazole

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-(1H-imidazol-1-yl)pyrimidine
134914-65-1

2-(1H-imidazol-1-yl)pyrimidine

Conditions
ConditionsYield
With potassium carbonate In neat (no solvent) at 160℃; for 3h; Schlenk technique; Inert atmosphere;99%
With copper(l) iodide; caesium carbonate In N,N-dimethyl-formamide at 20 - 100℃; for 24.5h;97%
With copper(l) iodide; caesium carbonate In N,N-dimethyl-formamide at 120℃; for 40h;97%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

para-methylphenylmagnesium bromide
4294-57-9

para-methylphenylmagnesium bromide

2-p-tolyl-pyrimidine
77232-13-4

2-p-tolyl-pyrimidine

Conditions
ConditionsYield
With N-heterocyclic carbene-based nickel(II) complex In tetrahydrofuran at 20℃; for 12h; Kumada reaction;99%
With chloro(1,3-bis(pyridin-2-ylmethyl)imidazolylidene)nickel(II) hexafluorophosphate In tetrahydrofuran at 20℃; for 12h; Kumada-Corriu coupling reaction; Inert atmosphere;99%
With C16H16Cl2CoN8(1+)*F6P(1-) In tetrahydrofuran at 20℃; for 2h; Kumada-Corriu cross-coupling;97%
With (IPr)Ni(π-allyl)Cl In tetrahydrofuran at 20℃; for 24h; Kumada Cross-Coupling; Inert atmosphere;74%
With [Ni(1-(1-ethyl-benzimidazol-2-ylmethyl)-3-mesitylimidazolin-2-ylidene)2][Cl]2; sodium acetate In tetrahydrofuran at 20℃; Kumada-Corriu coupling reaction; Inert atmosphere;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

p-tolylzinc(II) chloride
90252-89-4

p-tolylzinc(II) chloride

2-p-tolyl-pyrimidine
77232-13-4

2-p-tolyl-pyrimidine

Conditions
ConditionsYield
With C21H18N8Ni2O(2+)*2F6P(1-) In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 20 - 80℃; Negishi coupling reaction;99%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

m-tolylboronic acid
17933-03-8

m-tolylboronic acid

2-(3-methylphenyl)-pyrimidine

2-(3-methylphenyl)-pyrimidine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃; Suzuki coupling reaction;99%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃; Suzuki coupling;93%
Suzuki coupling;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

3-(pyrimidin-2-ylamino)propan-1-ol
959052-29-0

3-(pyrimidin-2-ylamino)propan-1-ol

Conditions
ConditionsYield
In ethanol for 18h; Reflux; Inert atmosphere;99%
With triethylamine In butan-1-ol at 125℃; for 1h; Temperature; Inert atmosphere; Microwave irradiation;87%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

tert-butyl 2-[(R)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
1414782-20-9

tert-butyl 2-[(R)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate

tert-butyl 2-[(R)-5-(pyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
1334785-04-4

tert-butyl 2-[(R)-5-(pyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane; water Suzuki Coupling; Inert atmosphere; Heating;99%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In water at 100℃; for 18h; Suzuki Coupling;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-(Trimethylsilyl)ethanol
2916-68-9

2-(Trimethylsilyl)ethanol

2-(2-(trimethylsilyl)ethoxy)pyrimidine

2-(2-(trimethylsilyl)ethoxy)pyrimidine

Conditions
ConditionsYield
Stage #1: 2-(Trimethylsilyl)ethanol With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: 2-chloropyrimidine In tetrahydrofuran at 25℃; for 24h;
99%
4,4-ethylenedioxycyclohexan-1-ol
22428-87-1

4,4-ethylenedioxycyclohexan-1-ol

2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-(1,4-dioxaspiro[4.5]decan-8-yloxy)pyrimidine
1361390-86-4

2-(1,4-dioxaspiro[4.5]decan-8-yloxy)pyrimidine

Conditions
ConditionsYield
Stage #1: 4,4-ethylenedioxycyclohexan-1-ol With 1H-imidazole; sodium hydride In N,N-dimethyl acetamide; mineral oil at 20℃; for 0.5h; Cooling with ice;
Stage #2: 2-chloropyrimidine In N,N-dimethyl acetamide; mineral oil at 20 - 60℃; for 3.5h;
98.59%
Stage #1: 4,4-ethylenedioxycyclohexan-1-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: 2-chloropyrimidine In N,N-dimethyl-formamide; mineral oil at 0 - 70℃; for 17h;
97%
Stage #1: 4,4-ethylenedioxycyclohexan-1-ol With sodium hydride In N,N-dimethyl-formamide for 0.333333h;
Stage #2: 2-chloropyrimidine at 20 - 100℃; for 9.5h;
Stage #1: 4,4-ethylenedioxycyclohexan-1-ol With sodium hydride In N,N-dimethyl-formamide for 0.333333h;
Stage #2: 2-chloropyrimidine In N,N-dimethyl-formamide at 100℃; for 9h;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

benzylamine
100-46-9

benzylamine

2-(benzylamino)pyrimidine
4214-59-9

2-(benzylamino)pyrimidine

Conditions
ConditionsYield
With cesium acetate; copper In dimethyl sulfoxide at 110℃; for 24h; Inert atmosphere;98%
at 100℃; for 0.1h; microwave irradiation;91%
With triethylamine In ethanol at 120℃; for 0.0833333h; Microwave irradiation;89%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

(2-propoxyphenyl)boronic acid
134896-34-7

(2-propoxyphenyl)boronic acid

2-(2-Propoxyphenyl)pyrimidine
134896-36-9

2-(2-Propoxyphenyl)pyrimidine

Conditions
ConditionsYield
<1,4-bis-(diphenylphosphine)butane>palladium(II)98%
With sodium carbonate; [1,4-bis(diphenylphosphino)butane] palladium(ll) dichloride In ethanol; toluene for 24h; Heating;98%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

2-(2-methylphenyl)pyrimidine
188527-65-3

2-(2-methylphenyl)pyrimidine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃; Suzuki coupling reaction;98%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃; Suzuki coupling;93%
With Tedicyp; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)) In xylene at 130℃; for 20h; Suzuki cross-coupling reaction;87%
Suzuki coupling;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

5-( 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one

5-( 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one

5-(pyrimidin-2-yl)-2,3-dihydro-1H-inden-1-one
1334784-74-5

5-(pyrimidin-2-yl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,2-dimethoxyethane; water at 20 - 95℃; Inert atmosphere;98%
With sodium carbonate In 1,2-dimethoxyethane at 95℃; Suzuki Coupling; Inert atmosphere;41%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

thiophenol
108-98-5

thiophenol

2-(pyrimidinylthio)benzene
14080-18-3

2-(pyrimidinylthio)benzene

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); 1,1',3,3'-tetrakis(diphenylphosphino)ferrocene; sodium t-butanolate In toluene for 17h; Catalytic behavior; Inert atmosphere; Schlenk technique; Heating;98%
With fac-tris[2-phenylpyridinato-C2,N]iridium(III); caesium carbonate In N,N-dimethyl-formamide at 25℃; for 18h; Schlenk technique; Inert atmosphere; Irradiation;83%
Stage #1: 2-chloropyrimidine With tris-(dibenzylideneacetone)dipalladium(0); triethylamine In toluene at 115℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #2: thiophenol In toluene at 115℃; for 24h; Reagent/catalyst; Time; Inert atmosphere; Schlenk technique;
72%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

1-Piperonylpiperazine
32231-06-4

1-Piperonylpiperazine

piribedil
3605-01-4

piribedil

Conditions
ConditionsYield
With C50H61Cl2N3Pd; potassium tert-butylate In 1,4-dioxane at 100℃; for 2h;98%
With C48H55ClN2Pd; sodium t-butanolate In 1,2-dimethoxyethane at 20℃; for 16h; Inert atmosphere; Sealed tube;98%
With potassium carbonate In tetrahydrofuran for 2h; Reflux;44%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

1H-Pyrazolo[3,4-b]pyridine
271-73-8

1H-Pyrazolo[3,4-b]pyridine

1-(pyrimidin-2-yl)-1H-pyrazolo[3,4-b]pyridine

1-(pyrimidin-2-yl)-1H-pyrazolo[3,4-b]pyridine

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; zinc diacetate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere;98%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

N,N-dimethyloctanamide
7378-99-6

N,N-dimethyloctanamide

A

2-(dimethylamino)pyrimidine
5621-02-3

2-(dimethylamino)pyrimidine

B

Methyl-octyl-pyrimidin-2-yl-amine
141193-16-0

Methyl-octyl-pyrimidin-2-yl-amine

Conditions
ConditionsYield
In tetrahydrofuran at 100℃; under 6000480 Torr; for 96h;A 2%
B 97%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

phenylboronic acid
98-80-6

phenylboronic acid

2-phenylpyrimidine
7431-45-0

2-phenylpyrimidine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃; Suzuki coupling reaction;97%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane at 90℃;95%
With oxygen; palladium diacetate; sodium carbonate In 1,4-dioxane at 90℃; Suzuki Coupling;93%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

2-fluoropyrimidine
31575-35-6

2-fluoropyrimidine

Conditions
ConditionsYield
With hydrogen fluoride at 50℃; for 1h; other aromatic halides, var. temp., also with HF-base systems;97%
With hydrogen fluoride at 50℃; for 1h;97%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

1-aza-18-crown-6
33941-15-0

1-aza-18-crown-6

16-(pyrimidin-2-yl)-1,4,7,10,13-pentaoxa-16-azacyclooctadecane

16-(pyrimidin-2-yl)-1,4,7,10,13-pentaoxa-16-azacyclooctadecane

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 100℃; under 6000480 Torr; for 96h;97%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

1-amino-2-propene
107-11-9

1-amino-2-propene

2-(prop-2-enylamino)pyrimidine
5176-93-2

2-(prop-2-enylamino)pyrimidine

Conditions
ConditionsYield
for 3h; Reflux;97%
at 20℃; for 2h;95%
for 2h; Heating; Yield given;
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

sodium thiophenolate
930-69-8

sodium thiophenolate

2-(pyrimidinylthio)benzene
14080-18-3

2-(pyrimidinylthio)benzene

Conditions
ConditionsYield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 85℃; for 0.00833333h; microwave irradiation;97%
In ethanol for 4h; Heating;14%

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