Items Standard Result Appearance Colorless to light yellow transparent liquid Conform Purity (GC)
Cas:141942-85-0
Min.Order:1 Gram
FOB Price: $2.0 / 5.0
Type:Manufacturers
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:141942-85-0
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Type:Manufacturers
inquiryAssay: 99% up; Stable supply with over 50Mt annually; Appearance:Transparent to light-yellow liquid Storage:room temprature Package:25kg/drum Application:Intermediate of Atrovastatin Calcium Port:Beijing/Shanghai/Shenzhen/Hangzhou
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $28.0 / 45.0
Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:141942-85-0
Min.Order:1
Negotiable
Type:Other
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:141942-85-0
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:141942-85-0
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryCHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $2.0 / 3.0
Type:Trading Company
inquiryProduct Name: Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Synonyms: (R)-(-)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-(-)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE;(R)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE;
Cas:141942-85-0
Min.Order:1 Gram
FOB Price: $8900.0
Type:Lab/Research institutions
inquiryAbout Product Technical Details Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Chemical Properties alpha -5 º (neat) Boiling point 2
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $1.0 / 3.0
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryProduct Name:Ethyl (R)-(-)-4-cyano-3-hydroxybutyate CAS No.:141942-85-0 EINECS: 430-220-6 Molecular Formula: C7H11NO3 Molecular Weight: 157.17 Appearance:Colorless liquid Appearance: Colorless Transparent Liquid Storage: Preserve in well-clos
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta
Cas:141942-85-0
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:141942-85-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $76.0 / 80.0
Type:Trading Company
inquiryEthyl (R)-(-)-4-cyano-3-hydroxybutyate CAS:141942-85-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high q
Cas:141942-85-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:141942-85-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:141942-85-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProduct Name: Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Synonyms: (R)-(-)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-4-CYANO-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-(-)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE;(R)-ETHYL 4-CYANO-3-HYDROXYBUTYRATE;(S)-4-CYANO
Cas:141942-85-0
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:141942-85-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryAppearance:Colorless to yellowish transparent liq... Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application: Pharmaceutical intermediates Transportation:Common products:
Cas:141942-85-0
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:141942-85-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:141942-85-0
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryFactory direct sales, accept customization. Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it
Cas:141942-85-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:141942-85-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci
Cas:141942-85-0
Min.Order:1 Kilogram
FOB Price: $150.0 / 180.0
Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:141942-85-0
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiry(3R)-4-cyano-3-hydroxybutyric acid ethyl esterAppearance:Colorless to light yellow liquid Storage:Kept in a cool, dry and ventilated place Package:according to customers' requirements Application:research chemicals Transportation:By air(EMS or EUB or
Cas:141942-85-0
Min.Order:1 Gram
Negotiable
Type:Other
inquirySuperior quality, moderate price & quick delivery. Appearance:Colorless to light yellow transparent liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:For
Cas:141942-85-0
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryethyl (2-chloroaceto)acetate
sodium cyanide
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With glucose dehydrogenase; ketoreductase In acetic acid butyl ester; water at 30 - 40℃; for 16h; Product distribution / selectivity; Aqueous phosphate buffer; | 98% |
sodium cyanide
(S)-4-bromo-3-hydroxy-butyric acid ethyl ester
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
at 50℃; for 3h; | 95% |
In N,N-dimethyl-formamide at 20℃; | 50% |
sodium cyanide
ethyl (S)-4-chloro-3-hydroxybutanoate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sulfuric acid; sodium hydroxide In water at 40℃; pH=7.3; Enzymatic reaction; | 93% |
With halohydrindehalogenase from parvibaculum lavamentivorans at 40℃; for 14h; pH=8; Kinetics; Enzymatic reaction; | 85% |
In water; N,N-dimethyl-formamide at 50℃; for 3h; | 70% |
(R)-3-hydroxy-4-cyano-butyric acid
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sulfuric acid In ethanol | 90% |
cyanoacetoacetic acid ethyl ester
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With D-glucose In phosphate buffer at 30℃; for 24h; pH=7; | 83.1% |
sodium cyanide
(S)-4-iodo-3-hydroxy-butyric acid ethyl ester
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
In ethanol; water at 45℃; for 3h; | 81% |
(S)-4-bromo-3-hydroxybutyric acid,ethyl ester
sodium cyanide
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
In water at 25 - 35℃; for 7.33h; pH=8 - 9.5; | 80% |
sodium cyanide
ethyl (S)-4-chloro-3-hydroxybutanoate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With acetic acid In water at 105 - 110℃; for 0.02125h; | 80% |
With sodium dihydrogen phosphate monohydrate In formamide at 65℃; for 1.25h; | 76.4% |
In water at 105℃; for 0.0133333h; | 67.4% |
ethanol
(R)-3-hydroxy-4-cyano-butyric acid
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sulfuric acid at 80℃; for 1h; | 62% |
hydrogenchloride In diethyl ether; ethanol at 20℃; for 30h; | |
With hydrogenchloride In diethyl ether; ethanol at 20℃; for 30h; Inert atmosphere; | |
With hydrogenchloride In diethyl ether at 20℃; for 30h; Inert atmosphere; |
ethanol
(R)-3-hydroxy-4-cyano-butyric acid
A
(R)-ethyl 4-cyano-3-hydroxybutyrate
B
(S)-3-hydroxy-4-cyanobutyric acid ethyl ester
Conditions | Yield |
---|---|
With hydrogenchloride at 20℃; for 0.5h; Title compound not separated from byproducts.; |
3-hydroxyglutaronitrile
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: nitrilase III; phosphate buffer / 22 h / 22 °C / pH 7 2: HCl / 0.5 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: water / 22 h / 22 °C / pH 7 2: hydrogenchloride / ethanol; diethyl ether / 30 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: water; A190H / aq. phosphate buffer / 21 °C / pH 7 / Enzymatic reaction 2: hydrogenchloride / diethyl ether / 30 h / 20 °C / Inert atmosphere View Scheme |
ethanol
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sulfuric acid at 0℃; for 1h; Heating / reflux; Neat (no solvent); |
(R)-potassium 3-hydroxy-4-cyano-butyrate
ethanol
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sulfuric acid at 0℃; | n/a |
diethyl sulfate
(S)-(-)-methyl-(3-hydroxy-4-bromo)-butanoate
(R)-3-hydroxy-4-cyano-butyric acid
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With hydrogenchloride; calcium hydroxide; sodium bicarbonate; calcium chloride; triethylamine In water; ethyl acetate |
(S)-4-bromo-3-hydroxy-butyric acid ethyl ester
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With NaCN In ethanol; water | 29.8 g (95%) |
sodium cyanide
ethyl (S)-4-chloro-3-hydroxybutanoate
A
(E)-ethyl 4-hydroxybut-2-enoate
B
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
In water at 55℃; for 3h; pH=8.5 - 9; Product distribution / selectivity; |
hydrogen cyanide
ethyl (S)-4-chloro-3-hydroxybutanoate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
Stage #1: hydrogen cyanide With halohydrin dehalogenase In water at 40℃; for 0.5h; pH=7; Stage #2: ethyl (S)-4-chloro-3-hydroxybutanoate In water for 21h; pH=7; Product distribution / selectivity; |
sodium cyanide
(S)-4-bromo-3-hydroxy-butyric acid ethyl ester
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
In ethanol; water |
sodium cyanide
ethyl (-)-(2S)-oxirane-2-acetate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With ammonia; nickel dichloride In aq. phosphate buffer; water at 30℃; pH=8; Kinetics; Enzymatic reaction; |
sodium cyanide
ethyl (2-chloroaceto)acetate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With vector pACYCDuet-RB and vector pET30-halohydrin dehalogenase in Escherichia coli BL21 (DE3) In aq. buffer at 30℃; for 2h; pH=7; Enzymatic reaction; stereoselective reaction; | n/a |
sodium cyanide
ethyl (2-chloroaceto)acetate
A
(R)-ethyl 4-cyano-3-hydroxybutyrate
B
(S)-3-hydroxy-4-cyanobutyric acid ethyl ester
Conditions | Yield |
---|---|
With vector pCDFDuet-HF and vector pET30-(S)-alcohol dehydrogenase in Escherichia coli BL21(DE3) In aq. buffer at 30℃; for 10h; pH=7; Enzymatic reaction; stereoselective reaction; | A n/a B n/a |
With halohydrin dehalogenase; NAD; magnesium chloride; alcohol dehydrogenase In tert-butyl methyl ether at 40℃; under 760.051 Torr; for 10h; pH=8; Solvent; Reagent/catalyst; Concentration; Time; Electrolysis; Sealed tube; Inert atmosphere; Enzymatic reaction; | A n/a B n/a |
ethyl (S)-4-chloro-3-hydroxybutanoate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With sodium cyanide; halohydrin dehalogenase In aq. phosphate buffer at 30℃; for 4h; pH=8; Enzymatic reaction; |
ethyl (2-chloroaceto)acetate
A
(E)-ethyl 4-hydroxybut-2-enoate
B
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: ketoreductase / acetic acid butyl ester; water / 11 h / pH 7 2: water / 3 h / 55 °C / pH 8.5 - 9 View Scheme |
ethyl (2-chloroaceto)acetate
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: ketoreductase / acetic acid butyl ester; water / 11 h / pH 7 2: water / 3 h / 55 °C / pH 8 View Scheme |
O-(4-methoxybenzyl)-trichloroacetimidate
(R)-ethyl 4-cyano-3-hydroxybutyrate
ethyl (R)-4-cyano-3-[(4-methoxybenzyl)oxy]butanoate
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane; cyclohexane at 25℃; for 3h; | 99% |
(R)-ethyl 4-cyano-3-hydroxybutyrate
(R)-ethyl-5-amino-3-hydroxy-5-oxopentanoate
Conditions | Yield |
---|---|
With Wilkinson's catalyst; 2,2-dimethylpropionaldehyde oxime In toluene at 110℃; for 4h; | 99% |
(R)-ethyl 4-cyano-3-hydroxybutyrate
4-hydroxy-δ-valerolactam
Conditions | Yield |
---|---|
With platinum(IV) oxide; hydrogen In methanol | 99% |
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With hydrazine In ethanol for 2h; | 98% |
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol for 10h; | 83% |
With ammonium hydroxide In methanol |
(R)-ethyl 4-cyano-3-hydroxybutyrate
methyl iodide
Conditions | Yield |
---|---|
With silver(l) oxide at 20℃; | 63.1% |
(R)-ethyl 4-cyano-3-hydroxybutyrate
1,2-dibromomethane
Conditions | Yield |
---|---|
Stage #1: 1,2-dibromomethane With lithium diisopropyl amide In tetrahydrofuran at -90℃; for 0.0666667h; Inert atmosphere; Flow reactor; Stage #2: (R)-ethyl 4-cyano-3-hydroxybutyrate In tetrahydrofuran at -90℃; Inert atmosphere; Flow reactor; | 22% |
t-butyl lithioacetate
(R)-ethyl 4-cyano-3-hydroxybutyrate
tert-butyl (5R)-6-cyano-5-hydroxy-3-carbonylhexanoate
Conditions | Yield |
---|---|
In tetrahydrofuran; hexane Yield given; |
(R)-ethyl 4-cyano-3-hydroxybutyrate
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran | |
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; |
(R)-ethyl 4-cyano-3-hydroxybutyrate
(R)-3-hydroxy-4-cyano-butyric acid
Conditions | Yield |
---|---|
With sodium hydroxide at 20℃; for 2h; | |
With sodium hydroxide; water for 2h; |
(R)-ethyl 4-cyano-3-hydroxybutyrate
[3-((R)-4-Cyano-3-hydroxy-butyrylamino)-propyl]-carbamic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aq. NaOH / 2 h / 20 °C 2: 64 percent / 1-hydroxybenzotriazole hydrate; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; aq. NaH2PO4 / dimethylformamide; tetrahydrofuran / 16 h / 20 °C / pH 5.7 - 6.0 View Scheme |
(R)-ethyl 4-cyano-3-hydroxybutyrate
(3-{(R)-4-Cyano-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-butyrylamino}-propyl)-carbamic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: aq. NaOH / 2 h / 20 °C 2: 64 percent / 1-hydroxybenzotriazole hydrate; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; aq. NaH2PO4 / dimethylformamide; tetrahydrofuran / 16 h / 20 °C / pH 5.7 - 6.0 3: 63 percent / N,N-diisopropylethylamine / CH2Cl2 / 3 h / 20 °C View Scheme |
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