Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:143491-57-0
Min.Order:1 Kilogram
FOB Price: $350.0
Type:Trading Company
inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:143491-57-0
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Powder Storage:-20°C Freezer Package:1kg/foil bag;
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Min.Order:25 Kilogram
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Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:143491-57-0
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryCHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis
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Min.Order:1 Kilogram
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Type:Trading Company
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Min.Order:1 Kilogram
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Type:Trading Company
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.
Cas:143491-57-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry[English Name] Emtricitabine [Test Method]HPLC [Purity]≥99% [CAS No.] 143491-57-0 [Mol. Formula]C8H10FN3O3S [Purity]> 99% by HPLC [Packaging]Package and quantity according to customer's detail requirement [Remark] In stock,
1.In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem (China) Co.,Ltd is Sp
Cas:143491-57-0
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:143491-57-0
Min.Order:10 Gram
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Type:Trading Company
inquiryProduct Name: Emtricitabine CAS: 143491-57-0 MF: C8H10FN3O3S MW: 247.25 EINECS: 604-363-1 Mol File: 143491-57-0.mol Emtricitabine Structure Emtricitabine Chemical Properties Melting point 136-140°C alpha D25 -133.60&de
Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA
Cas:143491-57-0
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryEmtricitabine CAS:143491-57-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedia
Cas:143491-57-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful
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Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:143491-57-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
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Cas:143491-57-0
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
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Min.Order:100 Milligram
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Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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Min.Order:0 Metric Ton
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inquiryNewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:143491-57-0
Min.Order:4 Kilogram
Negotiable
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Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:143491-57-0
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiry2',3'-dideoxy-5-fluoro-3'-thiacytidine hydrochloride
emtricitabine
Conditions | Yield |
---|---|
With triethylamine In methanol at 15 - 60℃; | 93.2% |
With triethylamine In methanol at 25 - 65℃; for 0.25h; Heating / reflux; | 82% |
With tributyl-amine In dichloromethane at 25 - 35℃; for 5.5h; | |
Amberlite LA2 liquid ion-exchange resin; | 25 g |
emtricitabine
Conditions | Yield |
---|---|
With triethylamine In ethanol at 50℃; for 1h; | 91.88% |
emtricitabine
Conditions | Yield |
---|---|
With Isopropyl acetate; triethylamine at 15 - 30℃; for 4h; Reagent/catalyst; | 90% |
In acetone for 2h; Reflux; | 87% |
emtricitabine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In methanol at 15 - 60℃; | 88.9% |
emtricitabine
Conditions | Yield |
---|---|
Stage #1: (+/-)-cis-2',3'-dideoxy-5-fluoro-3'-thiacytidine With 1,1'-bi-2-naphthol In methanol Reflux; Stage #2: With hydrogenchloride In water; ethyl acetate for 0.5h; pH=2 - 3; | 88.9% |
emtricitabine
Conditions | Yield |
---|---|
With methanol; potassium carbonate at 0 - 25℃; for 3h; | 87.34% |
emtricitabine
Conditions | Yield |
---|---|
With potassium carbonate In methanol at 0 - 25℃; for 3h; | 86% |
With potassium carbonate In methanol at 0 - 25℃; for 3.5h; | 82% |
emtricitabine
Conditions | Yield |
---|---|
Stage #1: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-[5-fluoro-2-oxo-4-(phenylcarboxamido)-1,2-dihydro-1-pyrimidinyl]-1,3-oxathiolane-2-carboxylate With methanol at 40℃; Inert atmosphere; Stage #2: With sodium tetrahydroborate; dipotassium hydrogenphosphate; water; sodium hydroxide In methanol at 20℃; for 1h; diastereoselective reaction; | 75% |
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathialane-2-carboxylate
emtricitabine
Conditions | Yield |
---|---|
With sodium tetrahydroborate; dipotassium hydrogenphosphate; water; sodium hydroxide In ethanol at 20℃; Temperature; | 70% |
Stage #1: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathiolane-2-carboxylate With sodium tetrahydroborate In methanol at -5℃; for 5h; Inert atmosphere; Stage #2: With isopropyl alcohol In water at 60℃; for 1h; Stage #3: With methanol In water Product distribution / selectivity; | 65% |
With methanol; sodium tetrahydroborate at -7 - -5℃; for 6h; Product distribution / selectivity; Inert atmosphere; | 65% |
emtricitabine
Conditions | Yield |
---|---|
With ammonia Ambient temperature; Yield given; |
(-)-(2R,5S)-5-fluoro-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N4-benzoylcytosine
emtricitabine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetra-n-butylammonium fluoride / tetrahydrofuran / 4 h / Ambient temperature 2: methanolic NH3 / Ambient temperature View Scheme |
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-[1,3]-oxathiolan-5-yl]-(1H)-pyrimidin-2-one monosuccinate
emtricitabine
Conditions | Yield |
---|---|
With triethylamine In isopropyl alcohol at 20℃; for 5h; |
5-(4-acetylamino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid 2-isopropyl-5-methyl-cyclohexyl ester
emtricitabine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: methanesulfonic acid / methanol / 4 h 1.2: 0.17 h 2.1: sodium hydroxide; dipotassium hydrogenphosphate; sodium tetrahydroborate / water; industrially methylated spirit / 4 h / 18 - 22 °C 2.2: 22 - 42 °C 3.1: triethylamine / isopropyl alcohol; water / 6 h / 6 - 20 °C View Scheme |
4-amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolane-5-yl)-1H-pyrimidin-2-one 2-fluorobenzoic acid salt
emtricitabine
Conditions | Yield |
---|---|
With triethylamine In water; isopropyl alcohol at 6 - 20℃; for 6h; |
emtricitabine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: (S)-2-phenylglycine / methanol / Reflux 1.2: 8 h / 20 °C 2.1: 1,1'-bi-2-naphthol / methanol / Reflux 2.2: 0.5 h / pH 2 - 3 View Scheme |
N,N-dimethyl-formamide dimethyl acetal
emtricitabine
Conditions | Yield |
---|---|
In methanol at 20℃; for 21h; | 100% |
emtricitabine
Conditions | Yield |
---|---|
With hydrogenchloride In isopropyl alcohol at 10 - 20℃; for 2h; Solvent; Temperature; | 93.6% |
tert-butyldimethylsilyl chloride
emtricitabine
4-amino-1-((2R,5S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 18h; | 90% |
With 1H-imidazole In tetrahydrofuran at 20℃; for 2h; Concentration; Inert atmosphere; Cooling; |
emtricitabine
isobutyl chloroformate
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 3.5h; Inert atmosphere; | 83% |
emtricitabine
methyl chloroformate
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere; | 68% |
dodecyl 1H-imidazole-1-carboxylate
emtricitabine
Conditions | Yield |
---|---|
With pyridine; potassium hydroxide In dichloromethane at 20℃; for 18h; Inert atmosphere; | 67% |
emtricitabine
carbonochloridic acid, butyl ester
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 3.5h; Inert atmosphere; | 60% |
emtricitabine
Conditions | Yield |
---|---|
Stage #1: emtricitabine With tert-butylmagnesium chloride In tetrahydrofuran at 0℃; for 0.5h; Stage #2: C17H21F5NO8P In tetrahydrofuran at 0 - 20℃; for 20h; | 53% |
tetra(n-butyl)ammonium hydroxide
emtricitabine
Conditions | Yield |
---|---|
Stage #1: emtricitabine With trichlorophosphate at 0℃; for 1h; Inert atmosphere; Stage #2: With water for 1h; Cooling with ice; Stage #3: tetra(n-butyl)ammonium hydroxide In water pH=7.0; | 36% |
Conditions | Yield |
---|---|
With copper(l) iodide; 9-azabicyclo<3.3.1>nonane-N-oxyl; oxygen; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl-formamide at 20℃; under 760.051 Torr; for 4h; Sealed tube; | 35% |
emtricitabine
Allyl chloroformate
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 15h; Inert atmosphere; | 23% |
emtricitabine
Conditions | Yield |
---|---|
With hydroxylamine hydrochloride In water for 24h; pH=6.0; | 16% |
emtricitabine
salicylic acid
Conditions | Yield |
---|---|
In water at 80℃; | 13% |
emtricitabine
(-)-5'-O-(t-butyldimethylsilyl)-N4-(4,4'-dimethoxytrityl)-5-fluoro-2',3'-dideoxy-3'-thiacytidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1H-imidazole / N,N-dimethyl-formamide / 18 h / 20 °C 2: pyridine / 0 - 20 °C View Scheme |
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