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Cas:147-94-4
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inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
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inquiryItems Standard Result Description White crystalline powder Off-white crystalline powder Solubility
Cas:147-94-4
Min.Order:1 Gram
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inquiryHubei Vanz Pharm Co. Ltd. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. We export to many countries and area with very competitive price, high quality, good ser
Factory supply Cytarabine CAS 147-94-4 with fast delivery Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives,
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Chinese Name: Ara Chinese Synonyms: 1-beta-D-arabinofuranosyl-4 - amino -2 (1H) - pyrimidinone; cytarabine; cytosine-β-D-furan arabinoside; cytosine arabinose; cytosine Arabic glycoside; arabinofuranosyl cytosine; cytosine arabino; 1-BETA-D
Cas:147-94-4
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Name:Cytosine-1-beta-D-arabinofuranoside CAS:147-94-4 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security witho
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WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiry1. Superior quality 2.Competitive price 3. Good service 4. Stock availability 5. Flexible payment Cytarabine CAS: 147-94-4 Appearance:Almost white to white crystalline powder Assay: NLT 99.0% Packing: 1kg/aluminum tin
HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting
Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
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inquiryBeluga chemical professional supply High quality Cytarabine CAS 147-94-4 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China and ex
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Min.Order:1 Gram
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Min.Order:1 Kilogram
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Min.Order:10 Gram
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inquiryCytarabine CAS: 147-94-4 Specification Items Standard Result Description White crystalline powder Off-white crystalline powder Solubility Freely
PRODUCT DETAILS
Cas:147-94-4
Min.Order:500 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With ammonia at 25℃; | 88% |
With ammonia for 16h; Ambient temperature; Yield given; |
ancitabine hydrochloride
arabinosyl cytosine
Conditions | Yield |
---|---|
In ethanol; water | 83% |
With potassium hydroxide In water for 0.333333h; Ambient temperature; pH=10.3; |
4-azido-ara-C
arabinosyl cytosine
Conditions | Yield |
---|---|
With hydrogen; palladium dichloride In methanol under 2585.7 Torr; for 30h; Ambient temperature; | 21% |
4-Amino-1-((2R,3S,4R,5R)-4-bromo-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; hydrochloride
A
cyclocitidine
B
arabinosyl cytosine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water-d2 for 168h; or 1-(3-iodo-3-deoxy-β-D-xylofuranosyl)cytosine hydrochloride (2c); |
cyclocitidine
arabinosyl cytosine
Conditions | Yield |
---|---|
With sodium hydroxide In methanol for 1h; Heating; Yield given; | |
With water In various solvent(s) at 40℃; Rate constant; other reagents, solvents; |
[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-carbamic acid methyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-carbamic acid ethyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-carbamic acid propyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-carbamic acid 2-methoxy-ethyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-carbamic acid octyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
benzyl 1-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylcarbamate
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid methyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid ethyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid propyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid pentyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid octyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid benzyl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
C37H57N3O7
arabinosyl cytosine
Conditions | Yield |
---|---|
With phosphate buffer; water; porcine liver esterase In ethanol at 37℃; Rate constant; |
arabinosyl cytosine
Conditions | Yield |
---|---|
With d(4)-methanol at 22℃; the rate of release of ara-C; other ara-C derivatives, other reagents, var. pH; |
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid benzyl ester
A
succinic acid monobenzyl ester
B
arabinosyl cytosine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; sodium carbonate at 25℃; Rate constant; various pH; |
arabinosyl cytosine
Conditions | Yield |
---|---|
With water Hydrolysis.wss.Loesung; |
arabinosyl cytosine
Conditions | Yield |
---|---|
In water; isopropyl alcohol G-values; Irradiation; |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 2.) 4-chlorophenyl dichlorophosphate / 1.) pyridine, 0 deg C, 12 h, 2.) pyridine, room temperature, 24 h 2: LiN3 / dimethylformamide / 3 h / 50 °C 3: 72 percent / 1N HCl / methanol / 26 h / Ambient temperature 4: 21 percent / H2 / PdCl2 / methanol / 30 h / 2585.7 Torr / Ambient temperature View Scheme | |
Multi-step reaction with 4 steps 1: 34.7 g / pyridine / 5 h / Ambient temperature 2: 89 percent / acetonitrile / 1.5 h / Ambient temperature 3: aq.ammonia / dioxane / 6 h / Ambient temperature 4: methanolic ammonia / 16 h / Ambient temperature View Scheme |
4-(1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl)pyrimidine-2(1H)one
arabinosyl cytosine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: LiN3 / dimethylformamide / 3 h / 50 °C 2: 72 percent / 1N HCl / methanol / 26 h / Ambient temperature 3: 21 percent / H2 / PdCl2 / methanol / 30 h / 2585.7 Torr / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 1: aq.ammonia / dioxane / 6 h / Ambient temperature 2: methanolic ammonia / 16 h / Ambient temperature View Scheme |
Acetic acid (2R,3S,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(4-azido-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester
arabinosyl cytosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 72 percent / 1N HCl / methanol / 26 h / Ambient temperature 2: 21 percent / H2 / PdCl2 / methanol / 30 h / 2585.7 Torr / Ambient temperature View Scheme |
2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl-4-thiouridine
arabinosyl cytosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90 percent / dimethyldioxirane, NH3 / acetone; CH2Cl2 / 25 °C 2: 88 percent / 2N methanol. NH3 / 25 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: triethylamine / H2O / 5 h / 70 °C 2: 34.7 g / pyridine / 5 h / Ambient temperature 3: 89 percent / acetonitrile / 1.5 h / Ambient temperature 4: aq.ammonia / dioxane / 6 h / Ambient temperature 5: methanolic ammonia / 16 h / Ambient temperature View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: diphenyl carbonate, sodium hydrogen carbonate / hexamethylphosphoric acid triamide / 0.33 h / 150 °C 2: triethylamine / H2O / 5 h / 70 °C 3: 34.7 g / pyridine / 5 h / Ambient temperature 4: 89 percent / acetonitrile / 1.5 h / Ambient temperature 5: aq.ammonia / dioxane / 6 h / Ambient temperature 6: methanolic ammonia / 16 h / Ambient temperature View Scheme |
1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil
arabinosyl cytosine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 89 percent / acetonitrile / 1.5 h / Ambient temperature 2: aq.ammonia / dioxane / 6 h / Ambient temperature 3: methanolic ammonia / 16 h / Ambient temperature View Scheme |
N,N-dimethyl-formamide dimethyl acetal
arabinosyl cytosine
N4-<(dimethylamino)methylene>arabinocytidine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 100% |
In N,N-dimethyl-formamide | 100% |
acetic anhydride
arabinosyl cytosine
N4-acetyl-1-<2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl>cytosine
Conditions | Yield |
---|---|
With dmap; triethylamine In N,N-dimethyl-formamide at 20℃; for 8h; | 100% |
Conditions | Yield |
---|---|
With cytidine deaminase enzyme In aq. phosphate buffer at 37℃; for 0.0833333h; pH=7; Enzymatic reaction; | 99% |
cytidine deaminase ( EC 3.5.4.5 ) at 37℃; for 48h; pH=6.8 with acetic acid; | |
With sodium hydroxide at 90.1℃; Rate constant; Mechanism; various reagent concentration, decomposition to nonchromophoric products; |
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
arabinosyl cytosine
1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]cytosine
Conditions | Yield |
---|---|
In pyridine for 1h; Ambient temperature; | 98% |
With pyridine at 20℃; for 4h; | 90% |
With pyridine at 25℃; for 2h; | 70% |
In pyridine for 3h; Ambient temperature; |
tert-butyldimethylsilyl chloride
arabinosyl cytosine
1-[2',3',5'-tris-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl]cytosine
Conditions | Yield |
---|---|
With pyridine; silver nitrate; triethylamine In tetrahydrofuran at 20℃; for 26h; silylation; | 98% |
With 1H-imidazole; dmap In N,N-dimethyl-formamide at 63℃; Cooling with ice; Inert atmosphere; | 90% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; | 85% |
acetyl chloride
arabinosyl cytosine
1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)cytosine hydrochloride
Conditions | Yield |
---|---|
With acetic acid In chloroform | 96% |
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 2 - 25℃; for 4h; | 96% |
With hydrogenchloride In diethyl ether |
Conditions | Yield |
---|---|
In ethanol at 65℃; for 4h; | 96% |
trityl chloride
arabinosyl cytosine
1-(5'-o-trityl-β-D-arabinofuranosyl)cytosine
Conditions | Yield |
---|---|
With pyridine at 20℃; for 20h; Inert atmosphere; regioselective reaction; | 95.2% |
With pyridine In water at 30℃; for 22h; Inert atmosphere; | 95.2% |
4,4'-dimethoxytrityl chloride
arabinosyl cytosine
4-Amino-1-{(2R,3S,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3,4-dihydroxy-tetrahydro-furan-2-yl}-1H-pyrimidin-2-one
Conditions | Yield |
---|---|
With pyridine In N,N-dimethyl-formamide at -5℃; for 1h; | 95% |
tert-butyldimethylsilyl chloride
arabinosyl cytosine
1-[3',5'-di(O-tert-butyldimethylsilyl)-β-D-arabinofuranosyl]cytosine
Conditions | Yield |
---|---|
With 3-picoline-N-oxide; silver nitrate In tetrahydrofuran for 2h; Ambient temperature; | 95% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 14h; | 92% |
With 1H-imidazole In N,N-dimethyl-formamide; toluene at -5 - 5℃; |
3-Acryloylamino-propionic acid pentafluorophenyl ester
arabinosyl cytosine
N-{2-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-ylcarbamoyl]-ethyl}-acrylamide
Conditions | Yield |
---|---|
With TEA In pyridine at 80℃; for 12h; | 95% |
benzoic acid anhydride
arabinosyl cytosine
1-(β-D-arabinofuranosyl)-N4-benzoylcytosine
Conditions | Yield |
---|---|
In ethanol for 4h; Heating; | 95% |
tert-butyldimethylsilyl chloride
arabinosyl cytosine
1-[5'-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl]cytosine
Conditions | Yield |
---|---|
With pyridine; 1H-imidazole at 20℃; for 3h; | 95% |
With pyridine Cooling with ice; Inert atmosphere; | 85.4% |
With pyridine; 1H-imidazole In 1,4-dioxane |
N,N-diisopropylformamide dimethyl acetal
arabinosyl cytosine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 93% |
In N,N-dimethyl-formamide | 93% |
O-(2,4-dinitrophenyl)hydroxylamine
arabinosyl cytosine
3-amino-1-β-D-arabinofuranosylcytosine hydrochloride
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 12h; Ambient temperature; | 93% |
N-(dimethoxymethyl)morpholine
arabinosyl cytosine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 93% |
In N,N-dimethyl-formamide | 93% |
Succinic acid 5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl ester pentafluorophenyl ester
arabinosyl cytosine
N-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-succinamic acid 5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl ester
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 72h; Ambient temperature; | 93% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 90% |
In N,N-dimethyl-formamide | 90% |
tert-butyldimethylsilyl chloride
arabinosyl cytosine
A
1-[3',5'-di(O-tert-butyldimethylsilyl)-β-D-arabinofuranosyl]cytosine
B
4-Amino-1-[(2R,3S,4R,5R)-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidin-2-one
Conditions | Yield |
---|---|
With 4-methylpyridine-1-oxide; silver nitrate In 1,2-dimethoxyethane for 2h; | A 90% B 5% |
With silver nitrate; triethylamine In 1,2-dimethoxyethane for 3h; Ambient temperature; | A 5% B 90% |
With triethylamine; silver nitrate In 1,2-dimethoxyethane for 3h; | A 5% B 90% |
mono-4-methoxytrityl chloride
arabinosyl cytosine
4-Amino-1-{(2R,3S,4S,5R)-3,4-dihydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidin-2-one
Conditions | Yield |
---|---|
With pyridine at 50℃; | 90% |
With pyridine for 22h; Ambient temperature; | 79% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 89% |
In N,N-dimethyl-formamide | 89% |
Conditions | Yield |
---|---|
Stage #1: ursodeoxycholic acid With triethylamine; isobutyl chloroformate In N,N-dimethyl-formamide at -15℃; for 0.25h; Inert atmosphere; Stage #2: arabinosyl cytosine With triethylamine In N,N-dimethyl-formamide at -15 - 20℃; for 0.5h; Inert atmosphere; | 87% |
Stage #1: ursodeoxycholic acid With triethylamine; isobutyl chloroformate In N,N-dimethyl-formamide at -15℃; for 0.0833333h; Stage #2: arabinosyl cytosine With triethylamine In N,N-dimethyl-formamide at -15 - 20℃; for 2.5h; |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide Ambient temperature; | 85% |
In N,N-dimethyl-formamide at 20℃; | 85% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 8h; Ambient temperature; | 85% |
In N,N-dimethyl-formamide | 85% |
N,N-dibutylformamide dimethyl acetal
arabinosyl cytosine
N4-[(dibutylamino)methylidene]arabinocytidine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide | 85% |
arabinosyl cytosine
Conditions | Yield |
---|---|
With pyridine at 20℃; for 72h; | 83% |
3-(tert-butyloxycarbonylamino)propionic acid
arabinosyl cytosine
tert-butyl 3-(1-((3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylamino)-3-oxopropylcarbamate
Conditions | Yield |
---|---|
Stage #1: 3-(tert-butyloxycarbonylamino)propionic acid With chloroformic acid ethyl ester; triethylamine In N,N-dimethyl-formamide at -15℃; for 0.5h; Stage #2: arabinosyl cytosine In N,N-dimethyl-formamide at -15 - 20℃; | 82% |
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