As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryItems Standard Result Assay 99.9%min 99.9% Hangzhou Dingyan Chem is a leading manufacturer and supplier of che
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inquirySpongouridine CAS 3083-77-0 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
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inquiry1-beta-D-Arabinofuranosyluracil Basic information Product Name: 1-beta-D-Arabinofuranosyluracil Synonyms: 1--D-Arabinofuranosyl-2,4(1H,3H)-pyrimidinedione;NSC 68928;1-BETA-D-ARABINOFURANOSYLURACIL;1-(β-D-Arabinopyranosyl)uracil;uracilarabi
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inquiry1-beta-D-Arabinofuranosyluracil CAS:3083-77-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:3083-77-0
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inquiryPRODUCT DETAILS
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inquirysuperior quality moderate price & quick delivery Appearance:White to Off-White Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Antivira
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
Cas:3083-77-0
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:3083-77-0
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inquiryNewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:3083-77-0
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inquiry1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil
araU
Conditions | Yield |
---|---|
With keratinase from Paecilomyces marquandii for 216h; pH=8; aq. phosphate buffer; Enzymatic reaction; | 100% |
Conditions | Yield |
---|---|
With cytidine deaminase enzyme In aq. phosphate buffer at 37℃; for 0.0833333h; pH=7; Enzymatic reaction; | 99% |
cytidine deaminase ( EC 3.5.4.5 ) at 37℃; for 48h; pH=6.8 with acetic acid; | |
With sodium hydroxide at 90.1℃; Rate constant; Mechanism; various reagent concentration, decomposition to nonchromophoric products; |
Conditions | Yield |
---|---|
With trifluoroacetic acid In N,N-dimethyl-formamide at 80℃; for 10h; | 95% |
With trifluoroacetic acid In N,N-dimethyl-formamide at 80℃; | 95% |
Stage #1: 2,2'-Anhydrouridine With sodium hydroxide; water at 20℃; for 18 - 20h; Stage #2: With hydrogenchloride; water pH=~ 6.5; | 88% |
2,2'-Anhydrouridine 3'-carbamate
araU
Conditions | Yield |
---|---|
With water; triethylamine at 60℃; for 48h; | 90% |
2,2''-anhydro-1-(3'',5''-di-O-acetyl-β-D-arabinofuranosyl)uracil
araU
Conditions | Yield |
---|---|
With sodium hydroxide for 4h; Ambient temperature; | 68% |
1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one
araU
Conditions | Yield |
---|---|
Stage #1: 1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one With hydrogenchloride; water at 80℃; for 2h; Stage #2: With sodium hydroxide pH=Ca. 7; | 68% |
Conditions | Yield |
---|---|
With bis(phenyl) carbonate; copper; sodium hydrogencarbonate In N,N-dimethyl-formamide at 140 - 150℃; for 45h; | 58.5% |
Multi-step reaction with 2 steps 1: 80 percent / diphenyl carbonate; NaHCO3 / dimethylformamide / 1.67 h / 140 °C 2: 95 percent / TFA / dimethylformamide / 10 h / 80 °C View Scheme | |
Multi-step reaction with 2 steps 1: 79 percent / (C6H5O)2CO / dimethylformamide 2: 61 percent / LiOH View Scheme |
diiminosuccinonitrile
uridine
A
2,2'-Anhydrouridine
B
araU
C
2,2'-Anhydrouridine 3'-carbamate
D
1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-pyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With diiminosuccinonitrile; Imidazole-HCl buffer at 2℃; for 96h; Further byproducts given; | A 10% B n/a C 54% D 5% |
araU
Conditions | Yield |
---|---|
Stage #1: C15H24N2O6 With diethylamino-sulfur trifluoride In dichloromethane Stage #2: With hydrogenchloride In methanol; water | 53% |
bromocyane
uridine
A
2,2'-Anhydrouridine
B
araU
C
2,2'-Anhydrouridine 3'-carbamate
D
Uridine 3'-carbamate
Conditions | Yield |
---|---|
With triethylamine In water at 2℃; for 0.75h; Further byproducts given; | A 4% B 13% C 37% D 27% |
bromocyane
uridine
A
2,2'-Anhydrouridine
B
araU
C
2,2'-Anhydrouridine 3'-carbamate
D
Uridine 3'-carbamate
E
2'-O-carbamoyluridine
F
1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-pyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With triethylamine In water at 2℃; for 0.75h; or with diiminosuccinonitrile; | A 2% B 13% C 37% D 27% E 2% F 4% |
bromocyane
uridine
A
araU
B
2,2'-Anhydrouridine 3'-carbamate
C
Uridine 3'-carbamate
D
1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-pyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With triethylamine In water at 2℃; for 0.75h; Further byproducts given; | A 13% B 37% C 27% D 4% |
uridine
A
araU
B
2,2'-Anhydrouridine 3'-carbamate
C
Uridine 3'-carbamate
D
1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-pyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With bromocyane; triethylamine In water at 2℃; for 45h; Further byproducts given; | A 13% B 37% C 27% D 4% |
Conditions | Yield |
---|---|
With bis(phenyl) carbonate; copper; sodium hydrogencarbonate In N,N,N,N,N,N-hexamethylphosphoric triamide at 150℃; for 20h; | A 30% B 35% |
diiminosuccinonitrile
uridine-5'-monophosphate sodium
A
2,2'-Anhydrouridine
B
araU
C
2,2'-Anhydrouridine 3'-carbamate
D
Uridine 3'-carbamate
Conditions | Yield |
---|---|
With Imidazole hydrochloride at 2℃; for 72h; Further byproducts given; | A 21% B 6% C 32% D 8% |
diiminosuccinonitrile
uridine-5'-monophosphate sodium
A
2,2'-Anhydrouridine
B
araU
C
2,2'-Anhydrouridine 3'-carbamate
D
Uridine 3'-carbamate
E
2'-O-carbamoyluridine
F
1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxotetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-pyrimidine-2,4(1H,3H)-dione
Conditions | Yield |
---|---|
With bovine alkaline phosphatase or with BrCN; | A 21% B 6% C 32% D 8% E 2% F 3% |
Conditions | Yield |
---|---|
With bis(phenyl) carbonate; copper; sodium hydrogencarbonate In N,N-dimethyl-formamide at 140 - 150℃; |
ara-UpUpU
araU
Conditions | Yield |
---|---|
With snake venom diasterease Product distribution; |
O2,2'-anhydro-1-(β-D-arabinofuranosyl)uracil
araU
Conditions | Yield |
---|---|
With sodium hydroxide In water Ambient temperature; |
Conditions | Yield |
---|---|
With water at 90℃; Rate constant; pH 3.63; |
ara-UpU
araU
Conditions | Yield |
---|---|
With snake venom diasterease Product distribution; |
B
araU
Conditions | Yield |
---|---|
Stage #1: 1-(2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl)-5-trimethylstannyl pyrimidine-2,4(3H)-dione With hexamethyldistannane; bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 100℃; for 2h; Stage #2: With sodium methylate In methanol at 0℃; for 7h; Stage #3: With sodium hydroxide; sodium (¹²⁵I)iodide; acetic acid; dihydrogen peroxide In chloroform for 0.0166667h; Further stages.; |
araU
Conditions | Yield |
---|---|
With sodium methylate In methanol at 0℃; for 7h; |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: NaH, H2(17)O (54.75percent) / dimethylformamide 2: CF3COOH (90percent) 3: 79 percent / (C6H5O)2CO / dimethylformamide 4: 61 percent / LiOH View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: CF3COOH (90percent) 2: 79 percent / (C6H5O)2CO / dimethylformamide 3: 61 percent / LiOH View Scheme | |
Multi-step reaction with 5 steps 1: pyridine 2: aqueous acetic acid 3: pyridine 4: methanol. NH3 5: aqueous H2SO4 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 83 percent / Et3N / methanol; H2O 2: 79 percent / (C6H5O)2CO / dimethylformamide 3: 61 percent / LiOH View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: H2(17)O (54.75percent) / CHCl3 2: 83 percent / Et3N / methanol; H2O 3: 79 percent / (C6H5O)2CO / dimethylformamide 4: 61 percent / LiOH View Scheme |
ancitabine hydrochloride
araU
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 2 M KOH / H2O / 0.33 h / Ambient temperature; pH=10.3 2: cytidine deaminase ( EC 3.5.4.5 ) / 48 h / 37 °C / pH=6.8 with acetic acid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / H2O / 1.33 h / 2 °C 2: 90 percent / H2O, triethylamine / 48 h / 60 °C View Scheme |
araU
acetic anhydride
1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil
Conditions | Yield |
---|---|
With dmap | 100% |
With dmap; triethylamine In acetonitrile at 20℃; | 96% |
With pyridine at 4℃; for 24h; | 91% |
Conditions | Yield |
---|---|
With uridine phosphorylase; disodium hydrogen arsenate heptahydrate; Escherichia coli purine nucleoside phosphorylase for 48h; Enzymatic reaction; | 99% |
Conditions | Yield |
---|---|
With uridine phosphorylase; disodium hydrogen arsenate heptahydrate; Escherichia coli purine nucleoside phosphorylase for 48h; Enzymatic reaction; | 98% |
araU
tert-butyldimethylsilyl chloride
1-[(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
Conditions | Yield |
---|---|
With silver nitrate; triethylamine In 1,2-dimethoxyethane for 5h; Ambient temperature; | 96% |
With triethylamine; silver nitrate In 1,2-dimethoxyethane for 5h; | 96% |
Conditions | Yield |
---|---|
Stage #1: araU With magnesium(II) chloride hexahydrate; recombinant E. coli uridine phosphorylase In aq. phosphate buffer at 40℃; for 72h; pH=7.0; Stage #2: With ammonium hydroxide; barium(II) acetate In aq. phosphate buffer at 4℃; pH=8.0; | A 96% B n/a |
benzoyl cyanide
araU
1-(tri-O-benzoyl-β-D-arabinofuranosyl)-1H-pyrimidine-2,4-dione
Conditions | Yield |
---|---|
With triethylamine In acetonitrile for 2h; Ambient temperature; | 95% |
para-chlorotoluene
araU
1-(2,3,5-tri-O-p-toluyl-β-D-arabinofuranosyl)uracil
Conditions | Yield |
---|---|
In pyridine 1.) 0 degC to R.T., 2.) 50 degC, 2 h; | 95% |
araU
tert-butyldimethylsilyl chloride
1-<3,5-bis-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl>-uracil
Conditions | Yield |
---|---|
With 3-picoline-N-oxide; silver nitrate In tetrahydrofuran for 2h; Ambient temperature; | 95% |
With 3-picoline-N-oxide; silver nitrate In tetrahydrofuran for 1.5h; | 95% |
Conditions | Yield |
---|---|
With N-Bromosuccinimide; sodium azide In 1,2-dimethoxyethane; water at 25℃; for 24h; | 95% |
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione In N,N-dimethyl-formamide at 25℃; for 1h; | 65% |
With N-Bromosuccinimide In ethanol; chloroform; N,N-dimethyl-formamide |
Conditions | Yield |
---|---|
With potassium dihydrogenphosphate; uridine phosphorylase; disodium hydrogen arsenate heptahydrate; Escherichia coli purine nucleoside phosphorylase In aq. phosphate buffer at 52 - 55℃; for 168h; pH=7; Enzymatic reaction; | 95% |
Conditions | Yield |
---|---|
With uridine phosphorylase; disodium hydrogen arsenate heptahydrate; Escherichia coli purine nucleoside phosphorylase In aq. phosphate buffer at 52℃; for 16h; pH=7; Enzymatic reaction; | 93% |
Conditions | Yield |
---|---|
With phosphate buffer; cell paste of Enterobacter aerogenes AJ 11125 at 60℃; for 15h; pH 7.0; several purine bases also investigated; | 92% |
With phosphate buffer; cell paste of Enterobacter aerogenes AJ 11125 at 60℃; for 15h; pH 7.0; | 92% |
With potassium dihydrogenphosphate at 60℃; for 15h; Enterobacter aerogenes AJ 11125, pH 7.0; | 87% |
Conditions | Yield |
---|---|
With uridine phosphorylase; disodium hydrogen arsenate heptahydrate; Escherichia coli purine nucleoside phosphorylase In aq. phosphate buffer at 52℃; pH=7; Enzymatic reaction; | 92% |
4,4'-dimethoxytrityl chloride
araU
1-{(2R,3S,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3,4-dihydroxy-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione
Conditions | Yield |
---|---|
With pyridine at -5℃; for 1h; | 90% |
araU
tert-butyldimethylsilyl chloride
A
1-<3,5-bis-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl>-uracil
B
1-[(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
C
1-[(2R,3S,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide for 40h; Product distribution; further solvents, reaction times, reagents, reagents and catalyst concentration,; | A 6% B 2% C 90% |
With 1H-imidazole In N,N-dimethyl-formamide for 40h; | A 6% B 2% C 90% |
araU
mono-4-methoxytrityl chloride
5'-O-monomethoxytritylarabinouridine
Conditions | Yield |
---|---|
With pyridine at 50℃; | 90% |
araU
1-(β-D-arabinofuranosyl)-5,6-dihydrouracil
Conditions | Yield |
---|---|
With hydrogen; Rh on carbon In water under 2400.2 Torr; for 16h; Ambient temperature; | 90% |
Conditions | Yield |
---|---|
With sodium azide; Iodine monochloride In acetonitrile at 25℃; for 36h; | 90% |
With ammonium cerium (IV) nitrate; iodine; acetic acid at 80℃; for 1h; | 82% |
With iodine; nitric acid In chloroform | 62% |
Multi-step reaction with 3 steps 1: 89 percent / pyridine / 0.5 h / 20 °C 2: 70 percent / I2; ceric(IV) ammonium nitrate / acetonitrile / 1 h / 80 °C 3: 80 percent / NaOMe / methanol / 0.5 h / 20 °C View Scheme | |
With iodine; nitric acid In chloroform |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; | 90% |
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
araU
5',3'-O-(tetraisopropyldisiloxane-1,3-di-yl)-1-β-D-arabinofuranosyl-uracil
Conditions | Yield |
---|---|
With pyridine at 0 - 20℃; | 89% |
With pyridine at 5 - 22℃; under 24 Torr; for 3h; regioselective reaction; | 86% |
With pyridine at 0 - 20℃; | 60.3% |
With pyridine | |
With pyridine |
araU
acetic anhydride
1-(2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl)-5-iodo-pyrimidine-2,4(3H)-dione
Conditions | Yield |
---|---|
Stage #1: araU; acetic anhydride With pyridine Stage #2: With ammonium cerium(IV) nitrate; iodine In acetonitrile | 88% |
Conditions | Yield |
---|---|
With phosphate buffer; cell paste of Enterobacter aerogenes AJ 11125 at 60℃; for 15h; pH 7.0; | 83% |
With dipotassium hydrogenphosphate; sodium azide; purine nucleoside phodphorylase ( EC 2.4.2.1 ); uridine phosphorylase ( EC 2.4.2.3 ) at 37℃; for 288h; pH=7.1; Yield given; | |
With potassium phosphate; Geobacillus thermoglucosidasius purine nucleoside phosphorylase; Thermus thermophilus pyrimidine nucleoside phosphorylase In water at 70℃; for 3h; pH=7; Enzymatic reaction; |
Conditions | Yield |
---|---|
In tetrahydrofuran at 60℃; for 7h; lipase from Candida antarctica (CAL SP435L); | 81% |
N-Acetylimidazole
araU
1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 4h; pH=8; | 78% |
Conditions | Yield |
---|---|
In 1,4-dioxane for 3h; Ambient temperature; Lipase SP435; | A 77% B 3% |
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