1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
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inquiryProduct Name: 2,4-dichloro-benzo[4,5]thieno[3,2-d]pyrimidine Synonyms: 2,4-dichloro-benzo[4,5]thieno[3,2-d]pyrimidine;2,4-dichlorobenzo[4,5]thieno[3,2-d]pyridine;2,4-Dichloro-[1]benzothieno[3,2-d]pyrimidine
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inquiry2,4-dichloro-benzo[4,5]thieno[3,2-d]pyrimidine CAS:160199-05-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing i
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inquirySuperiority Product Detail Minimum Order Qty.
Cas:160199-05-3
Min.Order:100 Kilogram
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:160199-05-3
Min.Order:10 Gram
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inquiryour strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery
Cas:160199-05-3
Min.Order:1 Gram
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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Min.Order:1 Kilogram
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inquiryWe are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)
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inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
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inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
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Min.Order:1 Kilogram
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inquiryOur company advantages: 1 The highest quality with the competitive price. 2、 Professional human services. 3、 The fastest and safest delivery service. 4、Our old customers all around the world. 5、 The high purity products. 6、We have a suf
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Type:Trading Company
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:160199-05-3
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inquiry2,4-dichlorobenzo[4,5]thieno[3,2-d]pyrimidine Name:2,4-dichlorobenzo[4,5]thieno[3,2-d]pyrimidine CAS No.:160199-05-3 Purity:99.50% Appearance:Detailed see specifications Storage:keep sealed and keep from direct light Package:
Cas:160199-05-3
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHigh quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
Cas:160199-05-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryStock products, own laboratoryAppearance:Off-white to gray solid powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:160199-05-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re
Cas:160199-05-3
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Type:Other
inquiryTAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp
Cas:160199-05-3
Min.Order:0
Negotiable
Type:Manufacturers
inquiry1.High purity, like 99%, 99.9%, 99.95%, 99.99%, 99.999%2.Quality control, test sample before shipping and keep sample for 3 years after shipping;3. Prompt shipment with professional documents;4. Packing as your request, with photo before shipment;5.
Cas:160199-05-3
Min.Order:0
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Type:Lab/Research institutions
inquiryfactory?direct?sale Application:healing drugs
Cas:160199-05-3
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Type:Lab/Research institutions
inquiryAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:160199-05-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryWe product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate
Cas:160199-05-3
Min.Order:0
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Type:Trading Company
inquiryfactory?direct?sale Application:healing drugs
Cas:160199-05-3
Min.Order:0
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Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
Cas:160199-05-3
Min.Order:0
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Type:Lab/Research institutions
inquiryexcellent quality and reliable supplierAppearance:COA mentioned Storage:COA mentioned Package:Standard or custom package Application:pharmaceutical raw materails Transportation:sea/air /courier Port:China main port
Cas:160199-05-3
Min.Order:0
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Type:Lab/Research institutions
inquirybulk?production Application:Pharmaceutical intermediates
Cas:160199-05-3
Min.Order:0
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Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:160199-05-3
Min.Order:0
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inquiryBest Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP
Cas:160199-05-3
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inquiry(benzo-1H-thieno[3,2-d]pyrimidine-2,4-dione)
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With trichlorophosphate | 85% |
With trichlorophosphate for 6h; Reflux; | 85% |
With trichlorophosphate for 6h; Reflux; | 85% |
2-fluorobenzonitrile
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: potassium tert-butylate / N,N-dimethyl-formamide 2: 2 h / 200 °C 3: trichlorophosphate View Scheme |
3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 2 h / 200 °C 2: trichlorophosphate View Scheme | |
Multi-step reaction with 2 steps 1: 2 h / 200 °C 2: trichlorophosphate / 6 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 1: 2 h / 200 °C 2: trichlorophosphate / 8 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 1: 2 h / 200 °C 2: trichlorophosphate / 7.5 h / Reflux View Scheme |
salicylonitrile
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylamine / dimethyl sulfoxide / 3 h / 100 °C 2: 2 h / 200 °C 3: trichlorophosphate / 6 h / Reflux View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
12,12-dimethyl-10,12-dihydro-10-azaindeno[2,1-b]fluorene
Conditions | Yield |
---|---|
With bis(tri-t-butylphosphine)palladium(0); sodium t-butanolate In 5,5-dimethyl-1,3-cyclohexadiene for 4h; Reflux; | 90% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 9h; Inert atmosphere; Heating; | 85% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
phenylboronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 7h; Inert atmosphere; Heating; | 83% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 9h; Inert atmosphere; Heating; | 83% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 7h; Heating; | 83% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 9h; Inert atmosphere; Heating; | 81% |
N-phenyl-9H-carbazol-3-boronic acid
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In tetrahydrofuran; water at 80℃; | 80% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
(9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In 1,4-dioxane; water at 80℃; | 78% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
9‐{[1,1'‐biphenyl]‐4‐yl}carbazol‐3‐ylboronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In tetrahydrofuran; water at 80℃; | 75% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
9,9-dimethyl-9H-fluoren-2-yl-2-boronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 3h; Suzuki Coupling; Reflux; | 74% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 12h; Reflux; | 71% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 12h; Reflux; | 71% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
9-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-9H-carbazole
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water for 6h; Reflux; Inert atmosphere; | 70% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
9‐{[1,1'‐biphenyl]‐4‐yl}carbazol‐3‐ylboronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; Alkaline conditions; | 70% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
3-Biphenylboronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 55℃; for 12h; Inert atmosphere; | 69% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; | 69% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; | 67% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; ethanol; water at 120℃; Alkaline conditions; | 65% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
9H-carbazole
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; | 60% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
4,4,5,5-tetramethyl-2-(naphthalen-2-yl)-1,3,2-dioxaborolane
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 6h; | 45% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 6h; | 45% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80 - 90℃; | 45% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80 - 90℃; | 45% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
1-naphthylboronic acid pinacol ester
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water | 45% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃; | 44% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃; | 44% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
4,4,5,5-tetramethyl-2-{8-oxatricyclo[7.4.02,7,]trideca-1(9),2,4,6,10,12-hexaen-4-yl}-1,3,2-dioxaborolane
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃; | 43% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃; | 43% |
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃; | 43% |
Conditions | Yield |
---|---|
Suzuki Coupling; | 35% |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
dimethyl amine
2-chloro-4-dimethylamino-benzo[4,5]thieno[3,2-d]pyrimidine
Conditions | Yield |
---|---|
In 1,4-dioxane; ethanol; water at 40℃; for 1h; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran; water / 80 - 90 °C / Alkaline conditions 2: tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate / toluene / 100 °C View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran; water / 80 - 90 °C / Alkaline conditions 2: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; tri-tert-butyl phosphine / toluene / 100 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 12 h / Reflux; Inert atmosphere 2: tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate / toluene; 5,5-dimethyl-1,3-cyclohexadiene / 15 h / Reflux; Inert atmosphere View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran; water / 80 - 90 °C / Alkaline conditions 2: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; tri-tert-butyl phosphine / toluene / 100 °C View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran; water / 80 - 90 °C / Alkaline conditions 2: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; tri-tert-butyl phosphine / toluene / 100 °C View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran; water / 80 - 90 °C / Alkaline conditions 2: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; tri-tert-butyl phosphine / toluene / 100 °C View Scheme |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
4-biphenylboronic acid
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran Reflux; |
2,4-dichlorobenzo[4,5]thiophene[3,2-d]pyrimidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane; water / 12 h / 55 °C / Inert atmosphere 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane; water / 12 h / Inert atmosphere; Reflux View Scheme |
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