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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-(4-OCTYLPHENYL)ETHANOL

Cas:162358-05-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(4-Octylphenyl)-ethanol

Cas:162358-05-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--2-(4-OCTYLPHENYL)ETHANOL

Cas:162358-05-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-(4-OCTYLPHENYL)ETHANOL

Cas:162358-05-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-(4-OCTYLPHENYL)ETHANOL CAS:162358-05-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2-(4-OCTYLPHENYL)ETHANOL CAS:162358-05-6

Cas:162358-05-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Benzeneethanol, 4-octyl

Cas:162358-05-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-(4-OCTYLPHENYL)ETHANOL

Cas:162358-05-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermediates T

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 2-(4-Ocytlphenyl)Ethanol CAS No.:162358-05-6 Molecule Formula:C16H26O Molecule Weight:234.37 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING IT

Best Quality 2-(4-Ocytlphenyl)Ethanol

Cas:162358-05-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

162358-05-6 CAS NO.162358-05-6

Cas:162358-05-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-(4-OCTYLPHENYL)ETHANOL

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

162358-05-6

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2-(4-Octylphenyl)ethanolAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

162358-05-6

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

Benzeneethanol, 4-octyl

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

Benzeneethanol, 4-octyl manufacturer

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-(4-Octylphenyl)ethanol

Cas:162358-05-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-(4-(oct-1-yn-1-yl)phenyl)-1-ethanol

2-(4-(oct-1-yn-1-yl)phenyl)-1-ethanol

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃; for 17h;98%
acetic acid 2-(4-octylphenyl)ethyl ester
162358-04-5

acetic acid 2-(4-octylphenyl)ethyl ester

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; for 8h;93%
With sodium methylate In methanol for 6h; Reflux;92%
With sodium methylate In methanol for 6h; Reflux;92%
1-bromo-octane
111-83-1

1-bromo-octane

C28H25BrO

C28H25BrO

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Stage #1: 1-bromo-octane With iodine; magnesium In tetrahydrofuran for 1h; Inert atmosphere; Reflux;
Stage #2: C28H25BrO With pyridine; dmap; sodium hydroxide Heating;
Stage #3: With palladium 10% on activated carbon; hydrogen In tetrahydrofuran at 120℃; for 4h;
80%
1-bromo-octane
111-83-1

1-bromo-octane

4-(2-hydroxyethyl)benzyl bromide
96044-43-8

4-(2-hydroxyethyl)benzyl bromide

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Stage #1: 1-bromo-octane With iodine; magnesium In diethyl ether for 1h; Inert atmosphere; Reflux;
Stage #2: 4-(2-hydroxyethyl)benzyl bromide With sodium hydroxide In tetrahydrofuran at 110℃; for 4h; Temperature;
75%
octylmagnesium bromide
17049-49-9

octylmagnesium bromide

acetic acid 2-[4-(trifluoromethanesulfonyloxy)phenyl]ethyl ester
712223-57-9

acetic acid 2-[4-(trifluoromethanesulfonyloxy)phenyl]ethyl ester

A

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

B

acetic acid 2-(4-octylphenyl)ethyl ester
162358-04-5

acetic acid 2-(4-octylphenyl)ethyl ester

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; iron(III)-acetylacetonate In tetrahydrofuran for 1h;A 20%
B 64%
1-Chlorooctane
111-85-3

1-Chlorooctane

4-(2-hydroxyethyl)benzyl bromide
96044-43-8

4-(2-hydroxyethyl)benzyl bromide

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Stage #1: n-chlorooctane With iodine; magnesium In tetrahydrofuran for 1h; Inert atmosphere; Reflux;
Stage #2: 4-(2-hydroxyethyl)benzyl bromide With sodium hydroxide In tetrahydrofuran at 120℃; for 4h;
20%
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 98 percent / NaHSO4 on silica / hexane / 26 h / Heating
2: 94 percent / pyridine / CH2Cl2 / 1 h / 20 °C
3: 20 percent / Fe(acac)3; NMP / tetrahydrofuran / 1 h
View Scheme
2-(4-hydroxyphenyl)ethyl acetate
58556-55-1

2-(4-hydroxyphenyl)ethyl acetate

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 94 percent / pyridine / CH2Cl2 / 1 h / 20 °C
2: 20 percent / Fe(acac)3; NMP / tetrahydrofuran / 1 h
View Scheme
n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 43 percent / AlCl3 / 1,2-dichloro-ethane / 3 h / 20 °C
2: triethylsilane; TFA / 1,2-dichloro-ethane / 3 h / 20 °C
3: 3.40 g / NaOMe; MeOH / 2 h / Heating
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1 h / 20 °C
1.2: 12 h / 20 °C
2.1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
3.1: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1 h / 20 °C
1.2: 12 h / 20 °C
2.1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
3.1: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / 0 - 20 °C
2: triethylsilane; trifluoroacetic acid / 20 °C
3: sodium methylate / methanol / 3 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / 0.01 h / 0.25 - 0.3 °C
1.2: 0 h / 0.2 - 0.5 °C
2.1: sodium hydroxide / water; methanol / 1.5 h / 0.1 - 0.3 °C
3.1: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
4.1: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
View Scheme
acetic acid phenethyl ester
103-45-7

acetic acid phenethyl ester

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 43 percent / AlCl3 / 1,2-dichloro-ethane / 3 h / 20 °C
2: triethylsilane; TFA / 1,2-dichloro-ethane / 3 h / 20 °C
3: 3.40 g / NaOMe; MeOH / 2 h / Heating
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1 h / 20 °C
1.2: 12 h / 20 °C
2.1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
3.1: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1 h / 20 °C
1.2: 12 h / 20 °C
2.1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
3.1: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / 0.01 h / 0.25 - 0.3 °C
1.2: 0 h / 0.2 - 0.5 °C
2.1: sodium hydroxide / water; methanol / 1.5 h / 0.1 - 0.3 °C
3.1: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
4.1: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
View Scheme
2-(4-octanoylphenyl)ethyl acetate
162358-03-4

2-(4-octanoylphenyl)ethyl acetate

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylsilane; TFA / 1,2-dichloro-ethane / 3 h / 20 °C
2: 3.40 g / NaOMe; MeOH / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
2: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: trifluoroacetic acid; triethylsilane / 3 h / 20 °C
2: sodium methylate / methanol / 6 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: triethylsilane; trifluoroacetic acid / 20 °C
2: sodium methylate / methanol / 3 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / water; methanol / 1.5 h / 0.1 - 0.3 °C
2: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
3: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
View Scheme
4-iodophenethyl alcohol
52914-23-5

4-iodophenethyl alcohol

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); copper(l) iodide; triethylamine / 17 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 17 h / 20 °C
View Scheme
n-octyne
629-05-0

n-octyne

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); copper(l) iodide; triethylamine / 17 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 17 h / 20 °C
View Scheme
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

4-octylphenethyl methanesulfonate
162358-06-7

4-octylphenethyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;95%
With triethylamine In dichloromethane at 20℃; for 5h;95%
With triethylamine In dichloromethane for 1h;
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate
162358-08-9

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: Et3N / CH2Cl2 / 1 h
2.1: 5.37 g / LiI / tetrahydrofuran / 4 h / 20 °C
3.1: NaH / dimethylformamide / 30 h
3.2: 82 percent / dimethylformamide / 1 h / 50 - 60 °C
View Scheme
Multi-step reaction with 3 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 61 percent / ethanol / 3 h / 65 °C
View Scheme
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 0.5 h
1.2: 3 h / 0 - 20 °C
2.1: sodium iodide / tetrahydrofuran / 20 °C
3.1: caesium carbonate / dimethyl sulfoxide / 3 h / 60 °C / Inert atmosphere
3.2: 60 - 80 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
2.2: 0.4 - 0.45 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 0 - 30 °C / Inert atmosphere
2: tetra-(n-butyl)ammonium iodide; sodium iodide / 3 h / Inert atmosphere
3: tetra-(n-butyl)ammonium iodide; caesium carbonate / dimethyl sulfoxide / 25 - 85 °C / Inert atmosphere
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

1-(2-iodoethyl)-4-octylbenzene
162358-07-8

1-(2-iodoethyl)-4-octylbenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Et3N / CH2Cl2 / 1 h
2: 5.37 g / LiI / tetrahydrofuran / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: Et3N / CH2Cl2 / 1 h / 20 °C
2: 16.0 g / NaI / butan-2-one / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 0.5 h
1.2: 3 h / 0 - 20 °C
2.1: sodium iodide / tetrahydrofuran / 20 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

fingolimod
162359-55-9

fingolimod

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 61 percent / ethanol / 3 h / 65 °C
4.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
5.1: 8.25 g / pyridine / 16 h / 20 °C
6.1: 2 N aq. LiOH / methanol / 2 h / Heating
View Scheme
Multi-step reaction with 4 steps
1.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
2.2: 0.4 - 0.45 °C / Inert atmosphere
3.1: calcium chloride / water; isopropyl alcohol / 0 h / 0.2 - 0.3 °C
3.2: 0.01 h / 0 - 0.5 °C
3.3: 0 h / 0.15 - 0.5 °C
4.1: sodium hydroxide / water; methanol / 2 h / Reflux
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-amino-2-hydroxymethyl-4-(4-octyl-phenyl)-butyric acid
296282-46-7

2-amino-2-hydroxymethyl-4-(4-octyl-phenyl)-butyric acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 75 percent / ethanol / 3 h / 65 °C
4.1: 54 percent / LiBH4 / tetrahydrofuran / 6 h / Heating
5.1: 66 percent / aq. HCl; AcOH / 7 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

3-isocyanato-3-[2-(4-octyl-phenyl)-ethyl]-dihydro-furan-2-one

3-isocyanato-3-[2-(4-octyl-phenyl)-ethyl]-dihydro-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
8.1: benzene / 1 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-amino-2-[2-(4-octylphenyl)ethyl]butane-1,4-diol

2-amino-2-[2-(4-octylphenyl)ethyl]butane-1,4-diol

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
8.1: benzene / 1 h / Heating
9.1: benzene / 7 h / Heating
10.1: LiBH4 / tetrahydrofuran / 0.5 h / Heating
11.1: pyridine / 13 h / 20 °C
12.1: Me3SiI / CH2Cl2 / 7 h
12.2: pyridine / 13 h
13.1: 2 M aq. LiOH / tetrahydrofuran; methanol / 2 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

N-[1-cyano-1-hydroxymethyl-3-(4-octylphenyl)propyl]acetamide
296282-78-5

N-[1-cyano-1-hydroxymethyl-3-(4-octylphenyl)propyl]acetamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 75 percent / ethanol / 3 h / 65 °C
4.1: 54 percent / LiBH4 / tetrahydrofuran / 6 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid
1027589-49-6

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-amino-2-[2-(4-octylphenyl)ethyl]pentane-1,5-diol

2-amino-2-[2-(4-octylphenyl)ethyl]pentane-1,5-diol

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: 76 percent / dimethylformamide / 3 h
4.1: KOH / ethanol / 6 h / 50 °C
5.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
6.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
7.1: benzene / 1 h / Heating
8.1: benzene / 7 h / Heating
9.1: LiBH4 / tetrahydrofuran / 3 h / Heating
10.1: 5 N aq. KOH / tetrahydrofuran; methanol / 13 h / Heating
11.1: HCl; MeOH / diethyl ether / 0.5 h
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide
249289-10-9

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 61 percent / ethanol / 3 h / 65 °C
4.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: triethylamine / dichloromethane / 0.5 h
1.2: 3 h / 0 - 20 °C
2.1: sodium iodide / tetrahydrofuran / 20 °C
3.1: caesium carbonate / dimethyl sulfoxide / 3 h / 60 °C / Inert atmosphere
3.2: 60 - 80 °C
4.1: sodium tetrahydroborate / methanol / 20 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid ethyl ester
1027929-75-4

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carbonyl azide

3-[2-(4-octyl-phenyl)-ethyl]-2-oxo-tetrahydro-furan-3-carbonyl azide

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

ethyl 2-acetamido-2-cyano-4-(4-octylphenyl)butyrate
296282-66-1

ethyl 2-acetamido-2-cyano-4-(4-octylphenyl)butyrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 75 percent / ethanol / 3 h / 65 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]-γ-butyrolactone
177259-57-3

2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]-γ-butyrolactone

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
8.1: benzene / 1 h / Heating
9.1: benzene / 7 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]butane 1,4-diol
177258-50-3

2-Methoxycarbonylamino-2-[2-(4-octylphenyl)ethyl]butane 1,4-diol

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
8.1: benzene / 1 h / Heating
9.1: benzene / 7 h / Heating
10.1: LiBH4 / tetrahydrofuran / 0.5 h / Heating
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
3.2: 61 percent / ethanol / 3 h / 65 °C
4.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
5.1: 8.25 g / pyridine / 16 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
2.2: 0.4 - 0.45 °C / Inert atmosphere
3.1: calcium chloride / water; isopropyl alcohol / 0 h / 0.2 - 0.3 °C
3.2: 0.01 h / 0 - 0.5 °C
3.3: 0 h / 0.15 - 0.5 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

C24H34O6

C24H34O6

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
View Scheme
2-(4-Octylphenyl)ethyl alcohol
162358-05-6

2-(4-Octylphenyl)ethyl alcohol

3-Acetamido-3-acetoxymethyl-5-(4-octylphenyl)pentyl acetate
177259-09-5

3-Acetamido-3-acetoxymethyl-5-(4-octylphenyl)pentyl acetate

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1.1: Et3N / CH2Cl2 / 1 h / 20 °C
2.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
3.1: NaH / dimethylformamide / 0.5 h
3.2: dimethylformamide / 3 h
4.1: 1 N aq. HCl / methanol / 5 h
5.1: 0.25 N aq. NaOH / acetone / 1.5 h / 20 °C
6.1: Et3N / tetrahydrofuran / 0.25 h / -5 °C
7.1: aq. NaN3 / tetrahydrofuran / 1 h / 0 °C
8.1: benzene / 1 h / Heating
9.1: benzene / 7 h / Heating
10.1: LiBH4 / tetrahydrofuran / 0.5 h / Heating
11.1: pyridine / 13 h / 20 °C
12.1: Me3SiI / CH2Cl2 / 7 h
12.2: pyridine / 13 h
View Scheme

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