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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

High purity 2-Amino-2',5-dichlorobenzophenone 98% TOP1 supplier in China

Cas:2958-36-3

Min.Order:100 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Amino-2',5-Dichloro Benzophenone supplier in China

Cas:2958-36-3

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Amino-2',5-Dichloro Benzophenone

Cas:2958-36-3

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

2-Amino-2',5-dichlorobenzophenone -- CHemwill

Cas:2958-36-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2-Amino-2',5-dichlorobenzophenone / LIDE PHARMA- Factory supply / Best price

Cas:2958-36-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2-Amino-2',5-dichlorobenzophenone-

Cas:2958-36-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 2958-36-3 with best quality

Cas:2958-36-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: 2-Amino-2,5-Dichloro Benzophenone Synonyms: 2-Amino-2',5-dichlorobenzophenone CAS: 2958-36-3 MF: C13H9Cl2NO Appearance: White powder Storage:Store in cool and dry place, away from sun light. Package:25KG/Drum Application:Organic Chemical

2-Amino-2,5-Dichloro Benzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Amino-2',5-dichlorobenzophenone 2958-36-3

Cas:2958-36-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Amino-5,2'-Dichloro Benzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(2-AMINO-5-CHLOROPHENYL)(2-CHLOROPHENYL)METHANONE

Cas:2958-36-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

2-Amino-2',5-dichlorobenzophenoneAppearance:Pls see the Details Storage:Keep away of light, hot, water, Store in dry, dark and ventilated place Package:according to customers' requirements Application:Steroids, Cosmetics Ingredients, APIs, Intermedia

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:yellow crystals powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Amino-2',5-dichlorobenzophenone Basic information Product Name: 2-Amino-2',5-dichlorobenzophenone Synonyms: (2-AMINO-5-CHLOROPHENYL)(2-CHLOROPHENYL)METHANONE;2'-AMINO-5'-CHLOROBENZOYL-2-CHLOROBENZENE;2-AMINO-5-CHLORO-2'-C

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:Light yellow to yellow crystal powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(2-amino-5-chlorophenyl)-(2-chlorophenyl)methanone cas no. 2958-36-3 98%

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Amino-2',5-dichlorobenzophenone

Cas:2958-36-3

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

5-chloro-3-(2-chlorophenyl)-2,1-benzisoxazole
77792-52-0

5-chloro-3-(2-chlorophenyl)-2,1-benzisoxazole

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With iron; acetic acid In ethanol; water at 60 - 70℃; for 2h;92%
2-amino-5-chlorobenzonitrile
5922-60-1

2-amino-5-chlorobenzonitrile

2-Chlorobenzeneboronic acid
3900-89-8

2-Chlorobenzeneboronic acid

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With 5,5'-dimethyl-2,2'-bipyridine; methanesulfonic acid; palladium(II) trifluoroacetate; water In 2-methyltetrahydrofuran at 80℃; for 36h; Schlenk technique;52%
o-chlorobenzoyl chloride
609-65-4

o-chlorobenzoyl chloride

4-chloro-aniline
106-47-8

4-chloro-aniline

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
(i) ZnCl2, (ii) aq. HCl, (iii) H2SO4; Multistep reaction;
With sulfuric acid; acetic acid; zinc(II) chloride 2) H2O, reflux, 18 h; Yield given. Multistep reaction;
With zinc(II) chloride at 200 - 230℃; for 3h;
N-[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-acetimidic acid ethyl ester

N-[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-acetimidic acid ethyl ester

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In xylene
lorazepam
846-49-1

lorazepam

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With hydrogenchloride for 0.5h; Heating; acid hydrolysis;
With hydroxypropyl-α-cyclodextrin In water for 0.75h; Heating;
lormetazepam
848-75-9

lormetazepam

A

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

B

lorazepam
846-49-1

lorazepam

Conditions
ConditionsYield
With hydrogenchloride multistep reaction: biotransformation, acid hydrolysis;
lormetazepam
848-75-9

lormetazepam

A

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

B

2',5-dichloro-2-methylaminobenzophenone
5621-86-3

2',5-dichloro-2-methylaminobenzophenone

Conditions
ConditionsYield
With hydrogenchloride multistep reaction: acid hydrolysis, photolysis;
ortho-chlorobenzoic acid
118-91-2

ortho-chlorobenzoic acid

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: SOCl2 / Heating
2.1: ZnCl2 / 2 h / 205 °C
2.2: 7- percent H2SO4 / 8 h / Heating
View Scheme
2-Chlorophenylacetonitrile
2856-63-5

2-Chlorophenylacetonitrile

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 12 percent / KOH, K2CO3, H2O / benzene; methanol / 2 h / Ambient temperature
2: 92 percent / Fe/AcOH / H2O; ethanol / 2 h / 60 - 70 °C
View Scheme
4-chlorobenzonitrile
100-00-5

4-chlorobenzonitrile

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 12 percent / KOH, K2CO3, H2O / benzene; methanol / 2 h / Ambient temperature
2: 92 percent / Fe/AcOH / H2O; ethanol / 2 h / 60 - 70 °C
View Scheme
tert-butyl [4-chloro-2-(2-chlorobenzoyl)phenyl]carbamate

tert-butyl [4-chloro-2-(2-chlorobenzoyl)phenyl]carbamate

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water Reflux;
Stage #1: tert-butyl [4-chloro-2-(2-chlorobenzoyl)phenyl]carbamate With hydrogenchloride; water In ethanol Reflux;
Stage #2: With sodium hydrogencarbonate In ethanol; water pH=8;
N-(t-butoxycarbonyl)-4-chloroaniline
18437-66-6

N-(t-butoxycarbonyl)-4-chloroaniline

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1.25 h / -40 °C / Inert atmosphere
2.1: hydrogenchloride; water / ethanol / Reflux
2.2: pH 8
View Scheme
4-chloro-aniline
106-47-8

4-chloro-aniline

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / toluene / 20 °C
2.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
2.2: 1.25 h / -40 °C / Inert atmosphere
3.1: hydrogenchloride; water / ethanol / Reflux
3.2: pH 8
View Scheme
N-methyl-N-methyloxy-2-amino-5-chlorobenzamide
150879-48-4

N-methyl-N-methyloxy-2-amino-5-chlorobenzamide

2-bromo-1-chlorobenzene
694-80-4

2-bromo-1-chlorobenzene

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
With n-butyllithium In tetrahydrofuran at -78℃; Inert atmosphere;
5-Chloroisatoic anhydride
4743-17-3

5-Chloroisatoic anhydride

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / ethanol / 0.17 h / 20 °C
1.2: 1.5 h / Reflux
2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine / ethanol; water / 0.17 h / 25 °C
1.2: 1.5 h / Reflux
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
View Scheme
5-chloroanthranilic acid
635-21-2

5-chloroanthranilic acid

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
1.2: Inert atmosphere; Reflux
2.1: n-butyllithium / tetrahydrofuran / -78 °C / Inert atmosphere
View Scheme
chloroacetyl chloride
79-04-9

chloroacetyl chloride

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2-chloroacetamido-2’,5-dichlorobenzophenone
14405-03-9

2-chloroacetamido-2’,5-dichlorobenzophenone

Conditions
ConditionsYield
In toluene at 10 - 20℃; for 3.5h;98.1%
With potassium carbonate In ethyl acetate at 10 - 20℃; for 1h; Cooling with ice;96.21%
In toluene for 0.0416667h; Microwave irradiation;88%
With N-ethyl-N,N-diisopropylamine In toluene at 10 - 20℃; for 3.5h;
dimethyl sulfate
77-78-1

dimethyl sulfate

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2',5-dichloro-2-methylaminobenzophenone
5621-86-3

2',5-dichloro-2-methylaminobenzophenone

Conditions
ConditionsYield
With sodium hydroxide; tetrabutylammomium bromide In tetrahydrofuran at 60℃; for 1h;98%
With tetrabutylammomium bromide; sodium hydroxide In tetrahydrofuran at 20℃; for 1h;
phenylacetylene
536-74-3

phenylacetylene

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2-phenyl-4-(2'-chlorophenyl)-6-chloroquinoline

2-phenyl-4-(2'-chlorophenyl)-6-chloroquinoline

Conditions
ConditionsYield
With propylphosphonium tetrachloroindate ionic liquid supported on nanosilica In neat (no solvent) at 110℃; for 0.583333h;98%
With indium(III) triflate at 110℃; for 0.075h; microwave irradiation;96%
With potassium dodeca tungstocobaltate trihydrate at 110℃; for 0.166667h; Microwave irradiation; neat (no solvent);96%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

(2-azido-5-chlorophenyl)(2-chlorophenyl)methanone

(2-azido-5-chlorophenyl)(2-chlorophenyl)methanone

Conditions
ConditionsYield
Stage #1: (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone With acetic acid; sodium nitrite In water at 0℃; for 1h;
Stage #2: With sodium azide In water for 1h;
98%
Stage #1: (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone With acetic acid; sodium nitrite In water at 0℃; for 1h; Inert atmosphere;
Stage #2: With sodium azide In water at 0 - 20℃; Inert atmosphere;
79%
Stage #1: (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone With hydrogenchloride; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: With sodium azide In water at 20℃; for 4h;
46%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

acetylacetone
123-54-6

acetylacetone

1-[6-chloro-4-(2-chlorophenyl)-2-methylquinolin-3-yl]ethan-1-one

1-[6-chloro-4-(2-chlorophenyl)-2-methylquinolin-3-yl]ethan-1-one

Conditions
ConditionsYield
With 1,3-dimethylimidazolium sulfate monomethyl ester; L-proline at 90℃; for 0.583333h; Knoevenagel Condensation; Green chemistry;96%
With Nd(NO3)3*6H2O In ethanol at 20℃; Friedlander reaction;94%
With phosphoric acid In ethanol for 12h; Reflux;93%
cyclohexane-1,2-dione
765-87-7

cyclohexane-1,2-dione

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

7-chloro-9-(2'-chlorophenyl)-2,3-dihydroacridin-4(1H)-one

7-chloro-9-(2'-chlorophenyl)-2,3-dihydroacridin-4(1H)-one

Conditions
ConditionsYield
With indium(III) chloride; 1-butyl-3-methylimidazolium Tetrafluoroborate at 100℃; for 2h;96%
With sulfuric acid; silica gel In methanol for 2h; Friedlaender Quinoline Synthesis; Reflux;93%
With eaton’s reagent In neat (no solvent) at 90℃; for 3h;86%
dimethylglyoxal
431-03-8

dimethylglyoxal

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2-acetyl-6-chloro-4-(2'-chlorophenyl)-quinoline

2-acetyl-6-chloro-4-(2'-chlorophenyl)-quinoline

Conditions
ConditionsYield
With indium(III) triflate; 1-butyl-3-methylimidazolium Tetrafluoroborate at 100℃; for 2h; Reagent/catalyst; Temperature; Solvent; Friedlaender Quinoline Synthesis; Ionic liquid;96%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2-amino-5-chloro-α-(2'-chlorophenyl)benzyl alcohol
74067-45-1

2-amino-5-chloro-α-(2'-chlorophenyl)benzyl alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol for 1.5h; Heating;95%
With sodium tetrahydroborate In methanol for 2h; Heating / reflux;91%
With sodium tetrahydroborate In ethanol
methyl 3-cyclopropyl-3-oxopropanoate
32249-35-7

methyl 3-cyclopropyl-3-oxopropanoate

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chloro-phenyl)-2-cyclopropyl-quinoline-3-carboxylic acid methyl ester

6-chloro-4-(2-chloro-phenyl)-2-cyclopropyl-quinoline-3-carboxylic acid methyl ester

Conditions
ConditionsYield
With aminosulfonic acid at 70℃; for 1h; Product distribution; Further Variations:; Solvents; Temperatures; time; Friedlander condensation;95%
With aminosulfonic acid at 70℃; for 1h; Friedlander condensation;95%
N-phthaloylglycine chloride
6780-38-7

N-phthaloylglycine chloride

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

5,2'-dichloro-2-(phtalimidoacetamido)benzophenone

5,2'-dichloro-2-(phtalimidoacetamido)benzophenone

Conditions
ConditionsYield
In chloroform for 6h; Heating;94%
2-Bromoacetyl bromide
598-21-0

2-Bromoacetyl bromide

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

2-(2-bromo-acetylamino)-5,2'-dichloro-benzophenone
5504-92-7

2-(2-bromo-acetylamino)-5,2'-dichloro-benzophenone

Conditions
ConditionsYield
With potassium carbonate In dichloromethane; water at 0℃; for 1h;94%
In diethyl ether at 10℃; for 2h;
In acetonitrile chemoselective reaction;
With sodium carbonate In dichloromethane; water at 0℃; for 2h;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

ethyl 6-chloro-4-(2-chlorophenyl)-2-methyl-3-quinolinecarboxylate

ethyl 6-chloro-4-(2-chlorophenyl)-2-methyl-3-quinolinecarboxylate

Conditions
ConditionsYield
With nickel(II) oxide In ethanol for 3h; Friedlaender Quinoline Synthesis; Reflux; Green chemistry;94%
With aminosulfonic acid at 70℃; for 1.25h; Friedlander condensation;91%
With Nd(NO3)3*6H2O In ethanol at 20℃; Friedlander reaction;87%
1,3-cylohexanedione
504-02-9

1,3-cylohexanedione

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

7-chloro-9-(2'-chlorophenyl)-3,4-dihydroacridin-1(2H)-one

7-chloro-9-(2'-chlorophenyl)-3,4-dihydroacridin-1(2H)-one

Conditions
ConditionsYield
With nickel(II) oxide In ethanol for 3h; Friedlaender Quinoline Synthesis; Reflux; Green chemistry;93%
With sulfuric acid; silica gel In methanol for 2h; Friedlaender Quinoline Synthesis; Reflux;93%
With aminosulfonic acid at 70℃; for 0.75h; Friedlander condensation;89%
5-(trifluoromethyl)-cyclohexane-1,3-dione
124612-15-3

5-(trifluoromethyl)-cyclohexane-1,3-dione

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

7-chloro-9-(2-chlorophenyl)-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one
1052719-52-4

7-chloro-9-(2-chlorophenyl)-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one

Conditions
ConditionsYield
With hydrogenchloride In water at 60 - 75℃; for 0.5h;93%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

4-n-methylphenylacetylene
766-97-2

4-n-methylphenylacetylene

6-chloro-4-(2-chlorophenyl)-2-(p-tolyl)quinoline
1285610-45-8

6-chloro-4-(2-chlorophenyl)-2-(p-tolyl)quinoline

Conditions
ConditionsYield
With potassium dodeca tungstocobaltate trihydrate at 110℃; for 0.25h; Microwave irradiation; neat (no solvent);93%
acetone
67-64-1

acetone

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chlorophenyl)-2-methylquinoline

6-chloro-4-(2-chlorophenyl)-2-methylquinoline

Conditions
ConditionsYield
With Nafion NR50 In ethanol at 200℃; for 1h; Microwave irradiation;93%
cyclohexanone
108-94-1

cyclohexanone

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

7-chloro-9-(2-chlorophenyl)-1,2,3,4-tetrahydroacridine

7-chloro-9-(2-chlorophenyl)-1,2,3,4-tetrahydroacridine

Conditions
ConditionsYield
With o-benzenedisulfonimide at 80℃; for 4h; Friedlaender synthesis; Neat (no solvent);92%
With 1,3,5-trichloro-2,4,6-triazine In ethanol for 0.833333h; Friedlander annulation; Heating;82%
With metal organic framework of 1,3-bis(carboxymethyl)imidazolium barium-1 complex In neat (no solvent) at 80℃; Microwave irradiation;81%
With silver dodecatungstophosphate In ethanol for 5.5h; Heating;80%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

acetylenedicarboxylic acid diethyl ester
762-21-0

acetylenedicarboxylic acid diethyl ester

diethyl 4-(2-chlorophenyl)-6-chloroquinoline-2,3-dicarboxylate
1220115-68-3

diethyl 4-(2-chlorophenyl)-6-chloroquinoline-2,3-dicarboxylate

Conditions
ConditionsYield
With indium(III) chloride at 80℃; for 0.833333h; regioselective reaction;92%
Stage #1: acetylenedicarboxylic acid diethyl ester With pyridine at 0 - 10℃; for 0.25h;
Stage #2: (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone at 20℃; for 14h;
86%
With β‐cyclodextrin In water at 65 - 75℃; for 6h;78%
formaldehyd
50-00-0

formaldehyd

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

N-[4-chloro-2-(2-chlorobenzoyl)phenyl]formamide
53960-31-9

N-[4-chloro-2-(2-chlorobenzoyl)phenyl]formamide

Conditions
ConditionsYield
In toluene Reflux;92%
1-methylcyclohexan-4-one
589-92-4

1-methylcyclohexan-4-one

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

C20H17Cl2N

C20H17Cl2N

Conditions
ConditionsYield
With 1,3-bis(carboxymethyl)-1H-imidazol-3-ium chloride In neat (no solvent) at 100℃; for 16h;92%
1-phenyl-2-tosylethanone
31378-03-7

1-phenyl-2-tosylethanone

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chlorophenyl)-2-phenyl-3-tosylquinoline

6-chloro-4-(2-chlorophenyl)-2-phenyl-3-tosylquinoline

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane at 150℃; for 1h; Microwave irradiation;92%
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

methyl iodide
74-88-4

methyl iodide

2',5-dichloro-2-methylaminobenzophenone
5621-86-3

2',5-dichloro-2-methylaminobenzophenone

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide Ambient temperature;91%
With potassium carbonate In N,N-dimethyl-formamide at 30℃; for 5h; Concentration; Solvent; Temperature;
1-phenyl-3-dimethylaminoprop-2-enone
1201-93-0

1-phenyl-3-dimethylaminoprop-2-enone

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

3-((4-chloro-2-(2-chlorobenzoyl)phenyl)amino)-1-phenylprop-2-en-1-one

3-((4-chloro-2-(2-chlorobenzoyl)phenyl)amino)-1-phenylprop-2-en-1-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In water at 20℃; for 0.333333h; Sonication; chemoselective reaction;91%
n-hexan-2-one
591-78-6

n-hexan-2-one

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chloro-phenyl)-2-methyl-3-propyl-quinoline

6-chloro-4-(2-chloro-phenyl)-2-methyl-3-propyl-quinoline

Conditions
ConditionsYield
With aminosulfonic acid at 70℃; for 1.25h; Friedlander condensation;90%
2-chloro-benzaldehyde
89-98-5

2-chloro-benzaldehyde

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

A

C20H11Cl3N2
1283752-29-3

C20H11Cl3N2

B

6-chloro-2-(2-chlorophenyl)-4-(2-chlorophenyl)-1,2-dihydroquinazoline
1283752-22-6

6-chloro-2-(2-chlorophenyl)-4-(2-chlorophenyl)-1,2-dihydroquinazoline

Conditions
ConditionsYield
With urea at 140℃; under 8175.82 Torr; for 0.0666667h; Neat (no solvent); Microwave irradiation; Closed vessel;A n/a
B 90%
3-Trifluoromethylbenzaldehyde
454-89-7

3-Trifluoromethylbenzaldehyde

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chlorophenyl)-2-(3-(trifluoromethyl)phenyl)quinazoline
1372890-88-4

6-chloro-4-(2-chlorophenyl)-2-(3-(trifluoromethyl)phenyl)quinazoline

Conditions
ConditionsYield
With Maltose; N,N'-Dimethylurea; ammonium acetate; ammonium chloride at 90℃; for 4h;90%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

methyl 6-chloro-4-(2-chlorophenyl)-2-methylquinoline-3-carboxylate
1309781-28-9

methyl 6-chloro-4-(2-chlorophenyl)-2-methylquinoline-3-carboxylate

Conditions
ConditionsYield
With 1,3-bis(carboxymethyl)-1H-imidazol-3-ium chloride In neat (no solvent) at 100℃; for 16h;90%
dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

dimethyl 4-(2-chlorophenyl)-6-chloroquinoline-2,3-dicarboxylate
1220115-67-2

dimethyl 4-(2-chlorophenyl)-6-chloroquinoline-2,3-dicarboxylate

Conditions
ConditionsYield
With tert-butylammonium hexafluorophosphate(V); calcium(II) trifluoromethanesulfonate In neat (no solvent) at 110℃; for 4.5h; Green chemistry; regioselective reaction;89%
With propylphosphonium tetrachloroindate ionic liquid supported on nanosilica In neat (no solvent) at 110℃; for 0.333333h;88%
Stage #1: dimethyl acetylenedicarboxylate With pyridine at 0 - 10℃; for 0.25h;
Stage #2: (2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone at 20℃; for 15h;
85%
With β‐cyclodextrin In water at 65 - 75℃; for 6h;82%
1-ethynyl-3-methoxybenzene
768-70-7

1-ethynyl-3-methoxybenzene

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone
2958-36-3

(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

6-chloro-4-(2-chlorophenyl)-2-(3-methoxyphenyl)-quinoline
1093059-25-6

6-chloro-4-(2-chlorophenyl)-2-(3-methoxyphenyl)-quinoline

Conditions
ConditionsYield
With potassium dodeca tungstocobaltate trihydrate at 110℃; for 0.166667h; Microwave irradiation; neat (no solvent);89%

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