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Hubei Vanz Pharm Co.,Ltd

Product advantage: Guaranteed quality Good pice Well packed Service advantage: Pre-sale service 1. Technical consultancy, to help customer know about the properties, features, quality, production and supply of the product they wa

Factory bulk supply high quality nootropic Phenibut powder

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $120.0 / 150.0

Type:Manufacturers

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Hubei Yuanmeng Biological Technology Co., Ltd.

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

99% Phenibut Hydrochloride CAS 3060-41-1 with Best Price

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $23.0 / 27.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Amino-4-phenylbutyric acid hydrochloride supplier in China

Cas:3060-41-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

β-(Aminomethyl)-benzenepropionic acid hydrochloride

Cas:3060-41-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:PHENIBUT CAS:3060-41-1 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability Produ

Factory bulk supply high quality nootropic Phenibut powder

Cas:3060-41-1

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--3060-41-1--3-Amino-4-phenylbutyric acid hydrochloride in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established sta

TIANFUCHEM--3060-41-1--3-Amino-4-phenylbutyric acid hydrochloride in stock

Cas:3060-41-1

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

3-Amino-4-phenylbutyric acid hydrochloride/ LIDE PHARMA- Factory supply / Best price

Cas:3060-41-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

3-Amino-4-Phenylbutyric Acid Hydrochloride CAS 3060-41-1

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $4.0 / 6.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenepropanoic acid, b-(aminomethyl)-, hydrochloride(1:1) 3060-41-1

Cas:3060-41-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Appearance:White Powder Storage:2 Years Package: according to customers' requirements Application:Phenibut is a derivative of the naturally occurring inhibitory neurotransmitter GABA Transportation:International express delivery Port: China main p

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $130.0 / 135.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Amino-4-phenylbutyric acid hydrochloride CAS:3060-41-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

3-Amino-4-phenylbutyric acid hydrochloride CAS:3060-41-1

Cas:3060-41-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phenibut Raw Powder

Cas:3060-41-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenepropanoic acid, b-(aminomethyl)-, hydrochloride(1:1)

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ShangHai Soyoung Biotechnology Inc

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye

Phenibut 3060-41-1 4-Amino-3-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:25 Kilogram

FOB Price: $120.0

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Fenibut

Cas:3060-41-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

High quality 3-Amino-4-phenylbutyric acid hydrochloride supplier in China

Cas:3060-41-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

High Quality 3-Amino-4-phenylbutyric acid hydrochloride 3060-41-1 In Stock

Cas:3060-41-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

High Purity 3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chemic

Benzenepropanoic acid, b-(aminomethyl)-, hydrochloride(1:1)

Cas:3060-41-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Amino-4-phenylbutyric acid HCl

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

High quality Phenibut

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Amino-4-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU CLAKE BIOTECH CO.,LTD

1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE Appearance:white crystalline powder Storage:in cool Package:as request Application:active pharmaceutical ingredient Transportation:Air / SEA BOTH OK Port:any po

Phenibut

Cas:3060-41-1

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-Amino-3-phenylbutyric acid hydrochloride

Cas:3060-41-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

C11H11N3O3

C11H11N3O3

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: C11H11N3O3 In tetrahydrofuran at 60℃; for 3h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 1.5h; Inert atmosphere;
91%
C17H19NO2*ClH

C17H19NO2*ClH

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr;90%
4-phenylpyrrolidin-2-one
1198-97-6

4-phenylpyrrolidin-2-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride; water for 12h; Reflux;88%
With hydrogenchloride In water for 12h; Reflux;88%
With hydrogenchloride In water for 16h; Sealed tube; Reflux;65%
With hydrogenchloride; water In water for 16h; Reflux;55%
diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate

diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate With hydrogenchloride In water at 120℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #2: In water at 120℃; for 0.333333h; Inert atmosphere; Schlenk technique;
88%
C13H17NO3

C13H17NO3

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride In water for 8h; Reflux;87%
diethyl 2-(3-nitrophenylethyl)malonate
71639-13-9

diethyl 2-(3-nitrophenylethyl)malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In isopropyl alcohol at 50℃; under 6840 - 7600 Torr; for 3h;2.85 g
3-chloro-5-hydroxy-4-phenylfuran-2(5H)-one

3-chloro-5-hydroxy-4-phenylfuran-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: acetic acid / chloroform / 1 h / 0 - 20 °C
1.2: 20 °C
2.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
3.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
4.1: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
3-chloro-1-(2,4-dimethoxybenzyl)-4-phenyl-1H-pyrrol-2(5H)-one

3-chloro-1-(2,4-dimethoxybenzyl)-4-phenyl-1H-pyrrol-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
2: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
3: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
3-chloro-4-phenyl-1H-pyrrol-2(5H)-one

3-chloro-4-phenyl-1H-pyrrol-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
2: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
phenylboronic acid
98-80-6

phenylboronic acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: cesium fluoride; tetrabutyl-ammonium chloride; bis-triphenylphosphine-palladium(II) chloride / toluene; water / 18 h / 20 °C / Inert atmosphere
2.1: acetic acid / chloroform / 1 h / 0 - 20 °C
2.2: 20 °C
3.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
4.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
5.1: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
ethyl 3-phenyl-4-nitrobutanoate
41441-40-1

ethyl 3-phenyl-4-nitrobutanoate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
2: hydrogenchloride; water / 12 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
2: hydrogenchloride / water / 12 h / Reflux
View Scheme
(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride; water / 12 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 24 h / 25 °C
2: calcined hydrotalcite / 24 h / Reflux
3: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: hydrogenchloride / water / 12 h / Reflux
View Scheme
2,2-dimethyl-5-(2-nitro-1-phenyleth-1-yl)-1,3-dioxane-4,6-dione
864294-75-7

2,2-dimethyl-5-(2-nitro-1-phenyleth-1-yl)-1,3-dioxane-4,6-dione

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
5-benzylidene Meldrum's acid
1214-54-6

5-benzylidene Meldrum's acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 6 h / 90 °C
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
benzaldehyde
100-52-7

benzaldehyde

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: calcined hydrotalcite / ethanol / 2 h / 90 °C
2: calcined hydrotalcite / 6 h / 90 °C
3: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 5 steps
1.1: calcined hydrotalcite / ethanol / 24 h / Reflux
1.2: calcined hydrotalcite / 24 h / Reflux; Enzymatic reaction
2.1: triethylamine / dichloromethane / 24 h / 25 °C
3.1: calcined hydrotalcite / 24 h / Reflux
4.1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
5.1: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 6 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: calcined hydrotalcite / ethanol / 24 h / Reflux
3: triethylamine / dichloromethane / 24 h / 25 °C
4: calcined hydrotalcite / 24 h / Reflux
5: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
6: hydrogenchloride / water / 12 h / Reflux
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: triethylamine / dichloromethane / 24 h / 25 °C
3: calcined hydrotalcite / 24 h / Reflux
4: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
5: hydrogenchloride / water / 12 h / Reflux
View Scheme
α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester
62384-61-6

α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester With hydrogen In methanol at 38 - 42℃; under 11251.1 - 30003 Torr; for 7h; Michael Addition;
Stage #2: With hydrogenchloride In water at 90 - 100℃; for 1h; Reagent/catalyst;
methyl cinnamate
103-26-4

methyl cinnamate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: methanol / 9 h / 20 °C
2.1: palladium 10% on activated carbon; hydrogen / butan-1-ol / 18 h / 20 °C / 22502.3 Torr
3.1: sodium hydroxide / water / 1 h / 60 °C
3.2: 3 h / 5 - 20 °C / pH 4
View Scheme
4-amino-3-phenylbutanoic acid methyl ester
84872-79-7

4-amino-3-phenylbutanoic acid methyl ester

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: 4-amino-3-phenylbutanoic acid methyl ester With sodium hydroxide In water at 60℃; for 1h;
Stage #2: With hydrogenchloride In water at 5 - 20℃; for 3h; pH=4;
53 g
3-phenylglutaric acid anhydride
4160-80-9

3-phenylglutaric acid anhydride

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydroxylamine hydrochloride; sodium hydroxide / isopropyl alcohol; water / 4 h / 60 - 65 °C
2: triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran / 20 h / 0 - 20 °C
3: triethylamine / 5 h / Reflux
4: hydrogenchloride / water / 8 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: trimethylsilylazide / chloroform / 1.5 h / -20 °C / Inert atmosphere
1.2: 0.25 h / -20 °C / Inert atmosphere
2.1: tetrahydrofuran / 3 h / 60 °C / Inert atmosphere
2.2: 1.5 h / 20 °C / Inert atmosphere
View Scheme
1-hydroxy-4-phenylpiperidine-2,6-dione

1-hydroxy-4-phenylpiperidine-2,6-dione

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran / 20 h / 0 - 20 °C
2: triethylamine / 5 h / Reflux
3: hydrogenchloride / water / 8 h / Reflux
View Scheme
nitromethane
75-52-5

nitromethane

benzaldehyde
100-52-7

benzaldehyde

diethyl malonate
105-53-3

diethyl malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: nitromethane; benzaldehyde In ethanol at -5℃;
Stage #2: With sodium methylate In ethanol for 2h;
Stage #3: diethyl malonate Reagent/catalyst; Further stages;
127 g
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

4-phenyl-1-(trimethylsilyl)-2-pyrrolidinone
106869-48-1

4-phenyl-1-(trimethylsilyl)-2-pyrrolidinone

Conditions
ConditionsYield
for 3h; Heating;99%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

4-((tert-butoxycarbonyl)amino)-3-phenylbutanoic acid
189014-01-5

4-((tert-butoxycarbonyl)amino)-3-phenylbutanoic acid

Conditions
ConditionsYield
With sodium hydroxide; sodium hydrogencarbonate In tert-butyl alcohol at 0 - 20℃; pH 10;95%
6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid

6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

(+/-)-4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-phenylbutanoic acid

(+/-)-4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-phenylbutanoic acid

Conditions
ConditionsYield
Stage #1: 6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: (±)-3-carboxy-2-phenylpropan-1-aminium chloride In N,N-dimethyl-formamide at 60℃;
90%
1-bromomethyl-1,2-dicarba-closo-dodecaborane(12)
19496-84-5

1-bromomethyl-1,2-dicarba-closo-dodecaborane(12)

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

C13H25B10NO2

C13H25B10NO2

Conditions
ConditionsYield
With triethylamine; 1-butyl-2,3-methylimidazolium tetrafluoroborate at 60 - 70℃; for 6h; Reagent/catalyst; Temperature;90%
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

4-(1H-tetrazol-1-yl)-3-phenylbutanoic acid

4-(1H-tetrazol-1-yl)-3-phenylbutanoic acid

Conditions
ConditionsYield
With sodium azide; acetic acid at 100℃; for 7h;31%
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

(3-Hydroxycarbamoyl-2-phenyl-propyl)-carbamic acid tert-butyl ester
189014-03-7

(3-Hydroxycarbamoyl-2-phenyl-propyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / NaHCO3, NaOH / 2-methyl-propan-2-ol / 0 - 20 °C / pH 10
2: 63 percent / N,N'-dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 1.) 0 deg C, 2 h, 2.) 6 deg C, 20 h
3: 93 percent / NH2OH / methanol / 1.) room temperature, 3 h, 2.) 6 deg C, 48 h
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

4-tert-Butoxycarbonylamino-3-phenyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester
189014-02-6

4-tert-Butoxycarbonylamino-3-phenyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / NaHCO3, NaOH / 2-methyl-propan-2-ol / 0 - 20 °C / pH 10
2: 63 percent / N,N'-dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 1.) 0 deg C, 2 h, 2.) 6 deg C, 20 h
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

4-Amino-N-hydroxy-3-phenyl-butyramide; hydrochloride

4-Amino-N-hydroxy-3-phenyl-butyramide; hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 95 percent / NaHCO3, NaOH / 2-methyl-propan-2-ol / 0 - 20 °C / pH 10
2: 63 percent / N,N'-dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 1.) 0 deg C, 2 h, 2.) 6 deg C, 20 h
3: 93 percent / NH2OH / methanol / 1.) room temperature, 3 h, 2.) 6 deg C, 48 h
4: 68 percent / HCl / dioxane / 0.25 h
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

methyl-2-oxo-4-phenylpyrrolidine-1-acetate
68497-63-2

methyl-2-oxo-4-phenylpyrrolidine-1-acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / 3 h / Heating
2: 94 percent / Me3SiOTf / 0.5 h / 150 - 155 °C
View Scheme
C11H11N3O3

C11H11N3O3

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: C11H11N3O3 In tetrahydrofuran at 60℃; for 3h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 1.5h; Inert atmosphere;
91%
C17H19NO2*ClH

C17H19NO2*ClH

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr;90%
4-phenylpyrrolidin-2-one
1198-97-6

4-phenylpyrrolidin-2-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride; water for 12h; Reflux;88%
With hydrogenchloride In water for 12h; Reflux;88%
With hydrogenchloride In water for 16h; Sealed tube; Reflux;65%
With hydrogenchloride; water In water for 16h; Reflux;55%
diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate

diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: diethyl 2-(2-((tert-butoxycarbonyl)amino)-1-phenylethyl)malonate With hydrogenchloride In water at 120℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #2: In water at 120℃; for 0.333333h; Inert atmosphere; Schlenk technique;
88%
C13H17NO3

C13H17NO3

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride In water for 8h; Reflux;87%
diethyl 2-(3-nitrophenylethyl)malonate
71639-13-9

diethyl 2-(3-nitrophenylethyl)malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In isopropyl alcohol at 50℃; under 6840 - 7600 Torr; for 3h;2.85 g
3-chloro-5-hydroxy-4-phenylfuran-2(5H)-one

3-chloro-5-hydroxy-4-phenylfuran-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: acetic acid / chloroform / 1 h / 0 - 20 °C
1.2: 20 °C
2.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
3.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
4.1: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
3-chloro-1-(2,4-dimethoxybenzyl)-4-phenyl-1H-pyrrol-2(5H)-one

3-chloro-1-(2,4-dimethoxybenzyl)-4-phenyl-1H-pyrrol-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
2: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
3: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
3-chloro-4-phenyl-1H-pyrrol-2(5H)-one

3-chloro-4-phenyl-1H-pyrrol-2(5H)-one

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
2: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
phenylboronic acid
98-80-6

phenylboronic acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: cesium fluoride; tetrabutyl-ammonium chloride; bis-triphenylphosphine-palladium(II) chloride / toluene; water / 18 h / 20 °C / Inert atmosphere
2.1: acetic acid / chloroform / 1 h / 0 - 20 °C
2.2: 20 °C
3.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C
4.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
5.1: hydrogenchloride; water / water / 16 h / Reflux
View Scheme
ethyl 3-phenyl-4-nitrobutanoate
41441-40-1

ethyl 3-phenyl-4-nitrobutanoate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
2: hydrogenchloride; water / 12 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
2: hydrogenchloride / water / 12 h / Reflux
View Scheme
(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride; water / 12 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 24 h / 25 °C
2: calcined hydrotalcite / 24 h / Reflux
3: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: hydrogenchloride / water / 12 h / Reflux
View Scheme
2,2-dimethyl-5-(2-nitro-1-phenyleth-1-yl)-1,3-dioxane-4,6-dione
864294-75-7

2,2-dimethyl-5-(2-nitro-1-phenyleth-1-yl)-1,3-dioxane-4,6-dione

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
5-benzylidene Meldrum's acid
1214-54-6

5-benzylidene Meldrum's acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 6 h / 90 °C
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
benzaldehyde
100-52-7

benzaldehyde

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: calcined hydrotalcite / 24 h / Reflux
2: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
3: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: calcined hydrotalcite / ethanol / 2 h / 90 °C
2: calcined hydrotalcite / 6 h / 90 °C
3: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 5 steps
1.1: calcined hydrotalcite / ethanol / 24 h / Reflux
1.2: calcined hydrotalcite / 24 h / Reflux; Enzymatic reaction
2.1: triethylamine / dichloromethane / 24 h / 25 °C
3.1: calcined hydrotalcite / 24 h / Reflux
4.1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
5.1: hydrogenchloride / water / 12 h / Reflux
View Scheme
Multi-step reaction with 6 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: calcined hydrotalcite / ethanol / 24 h / Reflux
3: triethylamine / dichloromethane / 24 h / 25 °C
4: calcined hydrotalcite / 24 h / Reflux
5: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
6: hydrogenchloride / water / 12 h / Reflux
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: calcined hydrotalcite / ethanol / 24 h / Reflux
2: triethylamine / dichloromethane / 24 h / 25 °C
3: calcined hydrotalcite / 24 h / Reflux
4: nickel(II) chloride hexahydrate; sodium tetrahydroborate / ethanol / 2 h / 0 °C
5: hydrogenchloride / water / 12 h / Reflux
View Scheme
α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester
62384-61-6

α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: α-phenyl-β-benzoyl-γ-nitrobutyrate ethyl ester With hydrogen In methanol at 38 - 42℃; under 11251.1 - 30003 Torr; for 7h; Michael Addition;
Stage #2: With hydrogenchloride In water at 90 - 100℃; for 1h; Reagent/catalyst;
methyl cinnamate
103-26-4

methyl cinnamate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: methanol / 9 h / 20 °C
2.1: palladium 10% on activated carbon; hydrogen / butan-1-ol / 18 h / 20 °C / 22502.3 Torr
3.1: sodium hydroxide / water / 1 h / 60 °C
3.2: 3 h / 5 - 20 °C / pH 4
View Scheme
4-amino-3-phenylbutanoic acid methyl ester
84872-79-7

4-amino-3-phenylbutanoic acid methyl ester

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: 4-amino-3-phenylbutanoic acid methyl ester With sodium hydroxide In water at 60℃; for 1h;
Stage #2: With hydrogenchloride In water at 5 - 20℃; for 3h; pH=4;
53 g
3-phenylglutaric acid anhydride
4160-80-9

3-phenylglutaric acid anhydride

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydroxylamine hydrochloride; sodium hydroxide / isopropyl alcohol; water / 4 h / 60 - 65 °C
2: triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran / 20 h / 0 - 20 °C
3: triethylamine / 5 h / Reflux
4: hydrogenchloride / water / 8 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: trimethylsilylazide / chloroform / 1.5 h / -20 °C / Inert atmosphere
1.2: 0.25 h / -20 °C / Inert atmosphere
2.1: tetrahydrofuran / 3 h / 60 °C / Inert atmosphere
2.2: 1.5 h / 20 °C / Inert atmosphere
View Scheme
1-hydroxy-4-phenylpiperidine-2,6-dione

1-hydroxy-4-phenylpiperidine-2,6-dione

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran / 20 h / 0 - 20 °C
2: triethylamine / 5 h / Reflux
3: hydrogenchloride / water / 8 h / Reflux
View Scheme
nitromethane
75-52-5

nitromethane

benzaldehyde
100-52-7

benzaldehyde

diethyl malonate
105-53-3

diethyl malonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

Conditions
ConditionsYield
Stage #1: nitromethane; benzaldehyde In ethanol at -5℃;
Stage #2: With sodium methylate In ethanol for 2h;
Stage #3: diethyl malonate Reagent/catalyst; Further stages;
127 g
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

4-phenyl-1-(trimethylsilyl)-2-pyrrolidinone
106869-48-1

4-phenyl-1-(trimethylsilyl)-2-pyrrolidinone

Conditions
ConditionsYield
for 3h; Heating;99%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

4-((tert-butoxycarbonyl)amino)-3-phenylbutanoic acid
189014-01-5

4-((tert-butoxycarbonyl)amino)-3-phenylbutanoic acid

Conditions
ConditionsYield
With sodium hydroxide; sodium hydrogencarbonate In tert-butyl alcohol at 0 - 20℃; pH 10;95%
6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid

6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

(+/-)-4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-phenylbutanoic acid

(+/-)-4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-phenylbutanoic acid

Conditions
ConditionsYield
Stage #1: 6-bromo-3-methyl-2-phenylquinoline-4-carboxylic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: (±)-3-carboxy-2-phenylpropan-1-aminium chloride In N,N-dimethyl-formamide at 60℃;
90%
1-bromomethyl-1,2-dicarba-closo-dodecaborane(12)
19496-84-5

1-bromomethyl-1,2-dicarba-closo-dodecaborane(12)

(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

C13H25B10NO2

C13H25B10NO2

Conditions
ConditionsYield
With triethylamine; 1-butyl-2,3-methylimidazolium tetrafluoroborate at 60 - 70℃; for 6h; Reagent/catalyst; Temperature;90%
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

4-(1H-tetrazol-1-yl)-3-phenylbutanoic acid

4-(1H-tetrazol-1-yl)-3-phenylbutanoic acid

Conditions
ConditionsYield
With sodium azide; acetic acid at 100℃; for 7h;31%
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

(3-Hydroxycarbamoyl-2-phenyl-propyl)-carbamic acid tert-butyl ester
189014-03-7

(3-Hydroxycarbamoyl-2-phenyl-propyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / NaHCO3, NaOH / 2-methyl-propan-2-ol / 0 - 20 °C / pH 10
2: 63 percent / N,N'-dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 1.) 0 deg C, 2 h, 2.) 6 deg C, 20 h
3: 93 percent / NH2OH / methanol / 1.) room temperature, 3 h, 2.) 6 deg C, 48 h
View Scheme
(±)-3-carboxy-2-phenylpropan-1-aminium chloride
3060-41-1

(±)-3-carboxy-2-phenylpropan-1-aminium chloride

4-tert-Butoxycarbonylamino-3-phenyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester
189014-02-6

4-tert-Butoxycarbonylamino-3-phenyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / NaHCO3, NaOH / 2-methyl-propan-2-ol / 0 - 20 °C / pH 10
2: 63 percent / N,N'-dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 1.) 0 deg C, 2 h, 2.) 6 deg C, 20 h
View Scheme

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